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  1. 761

    Association of Depression with Age at Natural Menopause: A Cross-Sectional Analysis with NHANES Data by An S, Ren S, Ma J, Zhang Y

    Published 2025-01-01
    “…Shuaiqi An,1,* Shiyan Ren,1,* Jiawen Ma,1 Yizhou Zhang1,2 1School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Zhejiang Famous Chinese Medicine Clinic, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yizhou Zhang, School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China, Email zhangyizhou2005@126.comPurpose: To evaluate the association between depression and age of natural menopause in American women.Patients and Methods: This cross-sectional study utilized eight cycles of the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2023. …”
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  2. 762

    Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections by Yan T, Wang Q, Ma C, Teng X, Gong Z, Chu W, Zhou Q, Liu Z

    Published 2025-02-01
    “…Tao Yan,1,2 Qiuyan Wang,2 Chengcheng Ma,2 Xuan Teng,2 Zhen Gong,2 Wenwen Chu,2 Qiang Zhou,2 Zhou Liu1 1Department of Clinical Laboratory Center, Anhui Chest Hospital, Hefei, 230031, People’s Republic of China; 2Department of Clinical Laboratory, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of ChinaCorrespondence: Zhou Liu, Department of Clinical Laboratory Center, Anhui Chest Hospital, Hefei, People’s Republic of China, Email liuzhou0112@ahmu.edu.cnPurpose: Klebsiella pneumoniae is a globally prevalent pathogen responsible for severe hospital- and community-acquired infections, and presents significant challenges for clinical management. …”
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  3. 763

    The Mediating Role of Cognitive Reappraisal on Bedtime Procrastination and Sleep Quality in Higher Educational Context: A Three-Wave Longitudinal Study by Zhang Y, Rehman S, Addas A, Ahmad M, Khan A

    Published 2025-01-01
    “…Yuan Zhang,1 Shazia Rehman,2 Abdullah Addas,3,4 Mehmood Ahmad,5 Ayesha Khan6 1College of Art, Nanyang Vocational College of Agriculture, Nan Yang, Henan, 47300, People’s Republic of China; 2Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, People’s Republic of China; 3Department of Civil Engineering, College of Engineering, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia; 4Landscape Architecture Department, Faculty of Architecture and Planning, King Abdulaziz University, Jeddah, 21589, Saudi Arabia; 5Department of Pharmacology and Toxicology, Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan; 6Department of Applied Psychology, Faculty of Social Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, PakistanCorrespondence: Shazia Rehman, Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, People’s Republic of China, Tel +86-13308429613, Email rehmanshazia.malik@gmail.comBackground: While bedtime procrastination is commonly associated with adverse outcomes such as poor sleep quality, the mechanisms mediating these effects remain underexplored. …”
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  4. 764
  5. 765

    Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment by Tian Z, Wang X, Chen S, Guo Z, Di J, Xiang C

    Published 2025-02-01
    “…Zui Tian,* Xudong Wang,* Shuai Chen,* Zijian Guo, Jingkai Di, Chuan Xiang Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuan Xiang, Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China, Email chuanxiang@sxmu.edu.cnAbstract: Macrophage immunotherapy is an emerging therapeutic approach designed for modulating the immune response to alleviate disease symptoms. …”
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  6. 766
  7. 767

    Antimicrobial Activity and Metabolomic Analysis of Linalool Against Pathogenic Bacteria Methicillin-Resistant Staphylococcus aureus by Long N, Qiu M, Zuo Y, Deng H

    Published 2025-02-01
    “…Nana Long,1,2 Min Qiu,2 Youwei Zuo,1 Hongping Deng1 1Center for Biodiversity Conservation and Utilization, School of Life Sciences, Southwest University, Beibei, Chongqing, People’s Republic of China; 2School of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence: Hongping Deng, Email denghp@swu.edu.cnPurpose: The purpose of this study was to evaluate the antibacterial activity and mechanism of linalool against Methicillin-resistant Staphylococcus aureus (MRSA).Methods: The determination of the antibacterial activity of linalool against clinically isolated MRSA strains was based on the minimum inhibitory concentration (MIC) and growth curve analysis. …”
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  8. 768

    Research Progress on Biomaterials for Spinal Cord Repair by Liao Z, Bao Q, Saijilahu, Chimedtseren C, Tumurbaatar K, Saijilafu

    Published 2025-02-01
    “…Zhenglie Liao,1,* Qianyi Bao,1,* Saijilahu,2 Chimedragchaa Chimedtseren,3 Khaliunaa Tumurbaatar,3 Saijilafu1 1Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, People’s Republic of China; 2Tongliao Centers for Disease Control and Prevention, Tongliao, Inner Mongolia, People’s Republic of China; 3Institute of Traditional Medicine and Technology of Mongolia, Ulaanbaatar city, Mongolia*These authors contributed equally to this workCorrespondence: Saijilafu, Email saijlf@hzcu.edu.cnAbstract: Spinal cord injury (SCI) is a very destructive disease of the central nervous system that often causes irreversible nerve damage. …”
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  9. 769

    Advances in Focal Segmental Glomerulosclerosis Treatment From the Perspective of the Newest Mechanisms of Podocyte Injury by Zhu Y, Xu G

    Published 2025-02-01
    “…Yan Zhu,1,2 Gaosi Xu1,2 1Department of Nephrology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang City, Jiangxi Province, People’s Republic of China; 2Jiangxi Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang City, Jiangxi Province, People’s Republic of ChinaCorrespondence: Gaosi Xu, Email gaosixu@163.comAbstract: Podocyte injury was widely recognized as a fundamental mechanism driving the progression of focal segmental glomerulosclerosis (FSGS). …”
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  10. 770
  11. 771

    Diabetic Ketoacidosis in Klinefelter Syndrome Sans Malignancy with Unusually Elevated Levels of CEA: A Case Report by Wo X, Yu X, Miao L, Mao Y, Tang K

    Published 2025-01-01
    “…Xinxin Wo, Xiaoyan Yu, Lingling Miao, Yushan Mao, Keke Tang Department of Endocrinology, The First Affiliated Hospital of Ningbo University, Ningbo University, Ningbo, People’s Republic of ChinaCorrespondence: Keke Tang, Department of Endocrinology, The First Affiliated Hospital of Ningbo University, Ningbo University, Ningbo, People’s Republic of China, Email lcyxtkk@126.comPurpose: Klinefelter’s syndrome (KS) is the most common sex chromosome disorder in the male population and is characterized by the presence of one or more X chromosomes. …”
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  12. 772

    Nanoparticle Therapies: Targeted Treatment for Bladder Cancer With Reduced Side Effects [Letter] by Sun J

    Published 2025-01-01
    “…Jingguo Sun Cheeloo College of Medicine, Shandong University, Jinan, Shandong, People’s Republic of ChinaCorrespondence: Jingguo Sun, Email 17863956872@163.com…”
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  13. 773

    The Substantial Role of Cell and NanoparticleSurface Properties in the Antibacterial Potential of Spherical Silver Nanoparticles [Letter] by Shen D

    Published 2025-01-01
    “…Danfeng Shen Department of General Surgery, Taicang Affiliated Hospital of Soochow University, Suzhou, 215400, People’s Republic of ChinaCorrespondence: Danfeng Shen, Email danfengsh@hotmail.com…”
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  14. 774

    Organ Function Preservation in Locally Advanced Low Rectal Cancer Through Total Neoadjuvant Therapy: A Case Report and Literature Review by Liu F, Yu L, Zhao Y, Li G, He X

    Published 2025-01-01
    “…Fengyuan Liu,* Li Yu,* Yuanyuan Zhao,* Guoliang Li,* Xinjia He* Department of Radiation Oncology, The Affiliated Hospital of Qingdao University Qingdao, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guoliang Li; Xinjia He, Department of Radiation Oncology, The Affiliated Hospital of Qingdao University Qingdao, Shandong, People’s Republic of China, Email liguoliang@qdu.edu.cn; hexinjia1974@163.comAbstract: Locally advanced rectal cancer (LARC) is a common malignancy that is often managed with neoadjuvant radiotherapy to downstage the tumor and increase the rate of complete response. …”
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  15. 775

    Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation by Liu H, Mei M, Zhong H, Lin S, Luo J, Huang S, Zhou J

    Published 2025-01-01
    “…Hong Liu,1,* Manxue Mei,1,* Hua Zhong,2 Shuyin Lin,1 Jiahui Luo,1 Sirong Huang,1 Jiuyao Zhou1 1Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China; 2Department of Gerontology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiuyao Zhou, Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China, Email yaoli@gzucm.edu.cn, zhoujiuyao@vip.tom.comBackground: Chronic kidney disease (CKD) is a progressive condition that arises from diverse etiological factors, resulting in structural alterations and functional impairment of the kidneys. …”
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  16. 776

    Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 by An W, Luo J, Zhang C, Xiao Q

    Published 2025-01-01
    “…Weiwei An,1,2 Jun Luo,3 Cheng Zhang,3 Qingzhong Xiao2 1Laboratory of Cardiovascular Science, Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, United Kingdom; 3Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of ChinaCorrespondence: Qingzhong Xiao, Centre for Clinical Pharmacology and Precision Medicine, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Heart Centre Charterhouse Square, London, EC1M 6BQ, United Kingdom, Tel +44(0)2078826584, Email q.xiao@qmul.ac.uk Cheng Zhang, Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email zhangcs05223@163.comBackground: Aortic aneurysm and dissection (AAD) represent a highly lethal cardiovascular condition. …”
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  17. 777

    Predictive Value of NT-proBNP for Functional Outcome of Ischemic Stroke Without Cardiac Disease: A Prospective, Observational Study by Liu R, Chen G, Zhao N, Yue W

    Published 2025-01-01
    “…Ran Liu,1 Guojuan Chen,2 Na Zhao,1 Wei Yue1 1Department of Neurology, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin Huanhu Hospital, Tianjin, 300350, People’s Republic of China; 2Department of Neurology, Tangshan Gongren Hospital, Tangshan, People’s Republic of ChinaCorrespondence: Wei Yue, Department of Neurology, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin Huanhu Hospital, No. 6 Jizhao Road, Shuanggang Town, Jinnan District, Tianjin, 300350, People’s Republic of China, Email hhyuewei2021@163.comPurpose: Our study aimed to evaluate the prognostic value of NT-proBNP in predicting adverse outcomes among patients with anterior circulation infarction (ACI) and posterior circulation infarction (PCI), specifically in those without pre-existing cardiac comorbidities.Patients and Methods: This single-center, prospective observational study enrolled patients with acute ischemic stroke (AIS) within 7 days of symptom onset. …”
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  18. 778

    Impact of Antimicrobial Stewardship and Infection Prevention and Control Programmes on Antibiotic Usage and A. baumannii resistance: A 2016–2023 Multicentre Prospective Study by Liu L, Liu B, Li L, Li Y, Zhou X, Li Q

    Published 2025-02-01
    “…Lei Liu,1,2,* Bin Liu,1,2,* Liang Li,1,2 Yu Li,3 Xiangdong Zhou,1,2 Qi Li1,2 1Department of Respiratory Medicine, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan, People’s Republic of China; 2Hainan Province Clinical Medical Center of Respiratory Disease, Haikou, Hainan, People’s Republic of China; 3Department of Respiratory Medicine, The Fourth Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li, Email lqlq198210@sina.comObjective: This study assesses the efficacy of antimicrobial stewardship (AMS) and infection prevention and control programmes (IPCP) in guiding the use of antibiotics and the control of A. baumannii (AB) resistance at multiple medical centres.Methods: We evaluated the effectiveness of the policy on antibiotic consumption and AB resistance by determining the relationship between the defined daily doses (DDD) for antibiotics – or alcohol-based hand gel (ABHG) consumption – and the incidence of carbapenem-resistant AB (CR-AB), multidrug-resistant AB (MDR-AB) and extensively drug-resistant AB (XDR-AB) at two medical centers from 2016– 2023.Results: In total, 4057 AB isolates were collected; 64.95% of the AB isolates were CR, 59.48% were MDR and 1.41% were XDR. …”
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  19. 779

    N-2-Hydroxypropyl Trimethyl Ammonium Chloride Chitosan-Aluminum Nano-Adjuvant Elicit Strong Immune Responses in Porcine Epidemic Diarrhea Inactivated Vaccine by Jin Z, Liu J, Guo S, Xu S, Gong X, Zhang C, Zhao K

    Published 2025-01-01
    “…Zheng Jin,1 Jiali Liu,1 Sihan Guo,2 Shangen Xu,1 Xiaochen Gong,1,3 Chunjing Zhang,3 Kai Zhao1,2 1Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, Taizhou Key Laboratory of Biomedicine and Advanced Dosage Forms, School of Life Sciences, Taizhou University, Taizhou, Zhejiang, 318000, People’s Republic of China; 2Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150080, China; Key Laboratory of Microbiology, College of Heilongjiang Province, School of Life Sciences, Heilongjiang University, Harbin, Heilongjiang, 150080, People’s Republic of China; 3School of Medical Technology, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, People’s Republic of ChinaCorrespondence: Kai Zhao; Chunjing Zhang, Email zybin395@126.com; cjzhang2005@163.comBackground: Porcine epidemic diarrhea virus (PEDV) inactivated vaccine lacks an effective vaccine adjuvant as an immune activator. …”
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  20. 780

    Predictors and Prognostic Effects of Perioperative Myocardial Injury After Transcatheter Aortic Valve Replacement According to VARC-3 Criteria by Hu X, Zhao Z, Wang C, Feng D, Chen Y, Niu G, Zhou Z, Zhang H, Li Z, Ye Y, Wang M, Wu Y

    Published 2025-02-01
    “…Xiangming Hu,1,* Zhenyan Zhao,1,* Can Wang,1,* Dejing Feng,1 Yang Chen,2 Guannan Niu,1 Zheng Zhou,1 Hongliang Zhang,1 Zhe Li,1 Yunqing Ye,1 Moyang Wang,1 Yongjian Wu1 1Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 2Department of Cardiology, Peking University People’s Hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Moyang Wang; Yongjian Wu, Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, People’s Republic of China, Email wangmoyang1983@vip.sina.com; fuwaiwyj@163.comPurpose: The impact of periprocedural myocardial injury (PPMI) according to VARC-3 criteria in patients undergoing transcatheter aortic valve replacement (TAVR) remains unclear. …”
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