Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction by Li T, Yang B, Liu X, Shi D, Wang Z, Chen Y, Shen C

“…Taixi Li,1,* Boshen Yang,1,* Xijian Liu,2 Dongmei Shi,1 Zhixiang Wang,1 Yizhi Chen,1 Chengxing Shen1 1Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China; 2School of Chemistry and Chemical Engineering, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent Equipment, Shanghai University of Engineering Science, Shanghai, 201620, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chengxing Shen, Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China, Email shencx@sjtu.edu.cnPurpose: Myocardial ischemia-reperfusion (IR) injury, a significant challenge in cardiovascular treatment, is primarily driven by ferroptosis and mitochondrial dysfunction. …”
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Dynamic Impact of the Sleep Disorder, Depression and Anxiety on the Cognitive Function in the First-Episode Depressive Patients by Zhang W, Zhou N, Li J

“…Wenqiong Zhang,1,* Nan Zhou,1,* Jie Li2 1Department of Mood Disorders, Tianjin Anding Hospital, Tianjin City, 300222, People’s Republic of China; 2The Dean’s Office, Tianjin Anding Hospital, Tianjin City, 300222, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jie Li, The Dean’s Office, Tianjin Anding Hospital, No. 13, Liulin Road, Hexi District, Tianjin City, 300222, People’s Republic of China, Tel +86-022-88188326, Email jielimd859@163.comBackground: Sleep disorder is closely related to depressive and anxious status as well as cognitive symptoms.Materials and Methods: A total of 173 cases with the first-episode major depressive disorder (MDD) were involved in this study. …”
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Causal Association Between Skin Microbiota and Malignant Melanoma: Genetic Insights From Mendelian Randomization by Li X, Wu S, Pan Y, Wu Z, Du Z, Xie W, Zhou Q

“…Xianglong Li,1 Shuang Wu,2 Yujie Pan,3 Ziyan Wu,3 Zhong Du,1 Wanying Xie,1 Qingyu Zhou1 1Department of Medical and Radiation Oncology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Critical Care, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 3School of Medicine, Yichun University, Yichun, People’s Republic of ChinaCorrespondence: Qingyu Zhou, Email zqy17@foxmail.comBackground: Malignant melanoma (MM) is an extremely aggressive type of skin cancer that represents a major risk to human health. …”
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The Role of Thickening Agent Proportions in Optimizing Nanoemulsion Gel for Dermatophytosis Treatment by Zhang X, Wu CC, Jiang H, Zhao JF, Pan ZJ, Zheng Y

“…Xiao Zhang,1,* Chen-Chen Wu,1 Hua Jiang,2 Jia-Fu Zhao,1,3 Zhong-Jian Pan,1 Yin Zheng1,3,* 1College of Animal Science, Guizhou University, Guiyang, Guizhou, People’s Republic of China; 2College of Veterinary Medicine, Gansu Agriculture University, Lanzhou, Gansu, People’s Republic of China; 3Key Laboratory of Animal Genetics, Breeding and Reproduction in The Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang, Guizhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yin Zheng, College of Animal Science, Guizhou University, Mingyi Building (Teaching and Research Center), Room 428, West Campus of Guizhou University, Huaxi District, Guiyang City, Guizhou Province, 550025, People’s Republic of China, Email yzheng@gzu.edu.cnBackground: Adjusting thickening agent proportions in nanoemulsion gel (NG) balances its transdermal and topical delivery properties, making it more effective for dermatophytosis treatment.Methods: Carbomer 940 and α-pinene were used as model thickening agent and antifungal, respectively. …”
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Inhibition of microRNA-139-5p Improves Fibroblasts Viability and Enhances Wound Repair in Diabetic Rats Through AP-1 (c-Fos/c-Jun) by Mo J, Zhang J, Meng X, Wang F, Tang W, Liu Y, Fu L, Liang F, Mo Z

“…Jiake Mo,1,2,* Jiaqi Zhang,1,2,* Xubiao Meng,3 Fang Wang,1,2 Weian Tang,1,2 Ying Liu,1,2 Lanfang Fu,3 Fang Liang,4 Zhaohui Mo1,2 1Department of Endocrinology, Third Xiangya Hospital of Central South University, Changsha, Hunan Province, People’s Republic of China; 2Diabetic Foot Research Center of Central South University, Changsha, Hunan Province, People’s Republic of China; 3Department of Endocrinology, Haikou People’s Hospital & Haikou Affiliated Hospital of Central South University Xiangya School of Medicine, Haikou, Hainan Province, People’s Republic of China; 4Department of Endocrinology, Xingtai People’s Hospital, Xingtai, Hebei Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaohui Mo; Fang Liang, Email easd04mzh@126.com; liangfang1024@163.comIntroductions: Diabetic foot ulcers (DFU) are notoriously difficult to heal, however, its underlying molecular mechanisms are unknown. …”
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Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

“…Yuhui Chen,1,* Ying Li,1,* Haoning Song,1,* Xiaochun Liu,1 Hongan Zhang,1 Jiaxin Jiang,2 Hongsheng Liu,2 Ribo Zhuo,1 Guoyun Cheng,1 Jia Fang,1 Lei Xu,1 Yong Qi,1 Dawei Sun1 1Department of Orthopedics and Traumatology, The Affiliated Guangdong second Provincial General Hospital of Jinan University, Guangzhou, Guangdong, 510315, People’s Republic of China; 2Guangdong Huayi Biomedical Science and Technology Center, Guangzhou, Guangdong, 511450, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Xu, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email orthoxl@163.com Dawei Sun, Department of Orthopedics and Traumatology, Guangdong second Provincial General Hospital of Jinan University, No. 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, People’s Republic of China, Email sundw@gd2h.org.cnBackground: A paramount issue in the realm of chronic wound healing among diabetic patients is the pervasive inflammatory response that persistently thwarts angiogenesis, thereby precipitating protracted delays in the healing process of such wounds. …”
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Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide by Xie Y, Zhu M, Bao H, Chen K, Wang S, Dai J, Chen H, Li H, Song Q, Wang X, Yu L, Pei J

“…Yizhuo Xie,1 Ming Zhu,1 Han Bao,1 Kejia Chen,1 Shanshan Wang,1 Jingwen Dai,1 Hongzhu Chen,1 He Li,1 Qi Song,2 Xinlu Wang,2 Liangping Yu,2 Jin Pei1 1Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, Changchun, People’s Republic of China; 2Department of Clinical Pharmacy, the First Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Jin Pei, Department of Biopharmacy, School of Pharmaceutical Sciences, Jilin University, No. 1163 Xinmin Street, Changchun, 130021, People’s Republic of China, Tel +86-431-85619725, Email peijin@jlu.edu.cn Liangping Yu, Department of Clinical Pharmacy, the First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130061, People’s Republic of China, Tel +86 431 81879802, Email liangpingyu@jlu.edu.cnPurpose: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. …”
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Magnetorotational Instability in Collisional Weakly Ionized Plasma with Distinct Species Velocities by Chenghao Zhang, Haijun Ren

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The dynamics of CD4+ T cell proliferation and regulation by Mingran Zhang, Junling Ma, Roderick Edwards, Meili Li

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Does urban green development attention improve energy resource misallocation? by Yongjian Lai, Xiangmin He

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Anomalous scattering of lumps for the extended Kadomtsev–Petviashvili equation arising in water wave by Haifang Song, Bo Ren

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Solar Coronal Mass Ejection and Post–Coronal Mass Ejection Blob Formation in Two-fluid Simulations by J. C. Du, Z. W. Ma

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A SPectroscopic Survey of Biased Halos in the Reionization Era (ASPIRE): Spectroscopically Complete Census of Obscured Cosmic Star Formation Rate Density at z = 4–6 by Fengwu Sun, Feige Wang, Jinyi Yang, Jaclyn B. Champagne, Roberto Decarli, Xiaohui Fan, Eduardo Bañados, Zheng Cai, Luis Colina, Eiichi Egami, Joseph F. Hennawi, Xiangyu Jin, Hyunsung D. Jun, Yana Khusanova, Mingyu Li, Zihao Li, Xiaojing Lin, Weizhe Liu, Romain A. Meyer, Maria A. Pudoka, George H. Rieke, Yue Shen, Wei Leong Tee, Bram Venemans, Fabian Walter, Yunjing Wu, Huanian Zhang, Siwei Zou

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Development and Evaluation of a Hypertension Prediction Model for Community-Based Screening of Sleep-Disordered Breathing by Feng T, Shan G, Hu Y, He H, Pei G, Zhou R, Ou Q

“…Tong Feng,1 Guangliang Shan,2 Yaoda Hu,2 Huijing He,2 Guo Pei,1 Ruohan Zhou,1 Qiong Ou1 1Sleep Center, Department of Geriatric Respiratory, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 2Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence: Qiong Ou, Sleep Center, Department of Geriatric Respiratory, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, No. 106 Zhongshan Road, Yuexiu District, Guangzhou City, Guangdong Province, People’s Republic of China, Tel +86 13609717251, Email ouqiong2776@hotmail.comPurpose: Approximately 30% of patients with sleep-disordered breathing (SDB) present with masked hypertension, primarily characterized by elevated nighttime blood pressure. …”
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The variability and predictability of summer southwest monsoon intensity measurement index across mainland indochina: from local synoptic to large scale perspectives by Kyaw Than Oo, Yinshuo Dong, Kazora Jonah

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Galaxies Lighting Up: Discovery of Seventy New Turn-on Changing-look Active Galactic Nuclei by Qian Yang, Paul J. Green, Xue-Bing Wu, Michael Eracleous, Linhua Jiang, Yuming Fu

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Application of Short Peptide Enteral Nutrition in Mechanically Ventilated Critically Ill Children with Severe Pneumonia and Its Impact on Patient Recovery by Xu Z, Ding Y, Deng XM, Mao XX, Xia PF, Li DR, Lu YP

“…Zhe Xu,1 Yi Ding,1 Xue-Mei Deng,1 Xiu-Xiu Mao,1 Ping-Fan Xia,1 Deng-Ran Li,1 Yong-Ping Lu2 1Department of Pediatrics, Guangyuan Central Hospital, Guangyuan, People’s Republic of China; 2Science & Technology Innovation Center, Guangyuan Central Hospital, Guangyuan, People’s Republic of ChinaCorrespondence: Yong-Ping Lu, Science & Technology Innovation Center, Guangyuan Central Hospital, Guangyuan, People’s Republic of China, Email luyongping_lyp@163.comObjective: To explore the application of short-peptide enteral nutrition formulation in mechanically ventilated pediatric patients with severe pneumonia and its impact on rehabilitation outcomes, providing practical clinical evidence for the nutritional support strategy in critically ill pneumonia children.Methods: This study retrospectively analyzed the clinical data of 90 neonatal pneumonia patients undergoing mechanical ventilation from May 2022 to December 2023. …”
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Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types by Gou XJ, Li LF, He XL, Chen X, Yu AY, Tian WY

“…Xian-Juan Gou,1 Lin-Fei Li,1 Xiao-Li He,1 Xi Chen,2 An-Yong Yu,1 Wei-Yan Tian1 1Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China; 2School of Nursing, Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of ChinaCorrespondence: Wei-Yan Tian, Department of Emergency, Affiliated Hospital of Zunyi Medical University, Zunyi City, Guizhou Province, 563000, People’s Republic of China, Tel +86 19184321912, Email 907359734@qq.comObjective: To comprehensively assess the impact of emergency transfusion of group O washed red blood cells on the vital signs and hematological parameters of patients with severe trauma and to analyze the differential responses among different blood types, thereby providing valuable evidence for optimizing transfusion strategies.Methods: A retrospective analysis was conducted on the clinical data of patients with severe trauma who underwent emergency transfusion in the hospital’s emergency department from April 2023 to March 2024. …”
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Impact of Hyperglycemia on Tear Film and Meibomian Gland Dysfunction: A Cross-Sectional Study by Meng F, Zhou Y, Bao T, Pang Y, Shao Q, Wang L, Zhao J, Li W, Xu H, Yang Y, Zhang B

“…Fanhua Meng,1,* Yuan Zhou,2,* Tong Bao,1,* Yunlei Pang,1 Qinglei Shao,1 Lifeng Wang,1 Jing Zhao,1 Wenchao Li,1 Haiyan Xu,1 Yajun Yang,1,2 Bozhou Zhang1,2 1Department of Retinal, Chifeng Chaoju Eye Hospital, Chifeng, People’s Republic of China; 2Department of Ocular Surface, Baotou Chaoju Eye Hospital, Baotou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yajun Yang; Bozhou Zhang, Department of ocular surface, Baotou Chaoju Eye Hospital, Baotou, Inner Mongolia Autonomous Region, 014060, People’s Republic of China, Email yangyajun@chaojueye.com; zhangbozhou@chaojueye.comPurpose: Elevated blood glucose levels may disrupt tear film and meibomian gland function, contributing to dry eye disease (DED) and meibomian gland dysfunction (MGD). …”
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Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

“…Qian Li,1 Dinglin Li,1 Ciqiu Tian,2 Xiangjie Liu,1 Hui Wang,1 Hao Liu1 1Liyuan Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Tongji Medical College of Science and Technology, Wuhan, People’s Republic of China; 2Hubei University of Chinese Medicine, Wuhan, People’s Republic of ChinaCorrespondence: Hao Liu, Liyuan Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Tongji Medical College of Science and Technology, Wuhan, People’s Republic of China, Email 729481937@qq.comPurpose: Osteoporosis is a common skeletal disease characterized by impaired bone microarchitecture, decreased bone mineral density and increased bone fragility, leading to a heavy physical and economic burden due to its greatly increased risk of fracture. …”
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