Crystal structure of 4-(2,2-difluoroethyl)-2,4-dimethyl-6-(trifluoromethyl)isoquinoline-1,3(2H,4H)-dione, C14H12F5NO2 by Liu Jianlian, Du Chaojun, Hao Hong

Get full text

The Joint Association of Sleep Quality and Outdoor Activity with Asthma and Allergic Rhinitis in Children: A Cross-Sectional Study in Shanghai by Lu R, Zhang Y, Chen Y, Lyu J, Li R, Kang W, Zhao A, Ning Z, Hu Y, Lin X, Tong S, Lu Z, Li S

“…Ruoyu Lu,1,* Ye Zhang,1,* Yiting Chen,1 Jiajun Lyu,1 Rong Li,1 Wenhui Kang,1 Anda Zhao,1,2 Zidi Ning,1 Yabin Hu,3 Xiaya Lin,4 Shilu Tong,3 Zhaohui Lu,3 Shenghui Li1,5 1School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 3National Children’s Medical Center, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 4Hainan Branch, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Sanya, Hainan Province, People’s Republic of China; 5MOE-Shanghai Key Laboratory of Children’s Environmental Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaohui Lu, National Children’s Medical Center; Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, 1678 Dongfang Road, Pudong District, Shanghai, 200127, People’s Republic of China, Tel +86-18930830796, Email luzhaohui@sjtu.edu.cn Shenghui Li, School of Public Health, Shanghai Jiao Tong University School of Medicine, 227 South Chongqing Road, Huangpu District, Shanghai, 200025, People’s Republic of China, Tel +86-21-63846590, Email lsh9907@163.com; submission9907@163.comPurpose: Aiming to investigate the combined association of sleep quality and outdoor activity with the risk of asthma and allergic rhinitis in children.Patients and Methods: 16,936 children from kindergartens and primary schools in 13 administrative districts of Shanghai, China were involved in the analyses. …”
Get full text

Early-life famine exposure may modify the association between long-term temperature variability and cardio-cerebrovascular diseases: a nationwide study by Yao Wu, BinBin Su, Junqing Xie, Bo Wen, Xiaolan Wu, Mengfan Wang, Yanhui Dong, Yi Song, Jun Ma

Get full text

Long-term Radio Monitoring of the Fast X-Ray Transient EP 240315a: Evidence for a Relativistic Jet by Roberto Ricci, Eleonora Troja, Yu-Han Yang, Muskan Yadav, Yuan Liu, Hui Sun, Xuefeng Wu, He Gao, Bing Zhang, Weimin Yuan

Get full text

Serum Lactate Dehydrogenase Is a Novel Predictor for the Severity in the Patients With MAFLD: A Cross-Sectional Study in Hefei, China by Yu L, Bao S, Zhu F, Xu Y, Zu F, Liu Y, Jiang R, Chen S, Chen W

“…Liang Yu,1,* Shiming Bao,2,* Feng Zhu,3,* Yanyan Xu,1 Fuqiang Zu,1 Yanwei Liu,1 Runbeng Jiang,1 Wei Chen,4 Song Chen5 1Department of General Surgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department of Emergency Surgery, Tongling People’s Hospital, Tongling, People’s Republic of China; 3Department of General Surgery, Tongling People’s Hospital, Tongling, People’s Republic of China; 4Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 5Department of General Surgery, the Affiliated Chuzhou Hospital of Anhui Medical University (The First People’s Hospital of Chuzhou), Chuzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Song Chen, Department of General Surgery, the Affiliated Chuzhou Hospital of Anhui Medical University (The First People’s Hospital of Chuzhou), Chuzhou, People’s Republic of China, Email chensong101425@163.com Wei Chen, Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China, Email 13665560109@163.comBackground & Aims: The aim of this study was to assess the association between the level of lactate dehydrogenase (LDH) and the severity of metabolic syndrome (MetS) and Metabolic Associated Fatty Liver Disease (MAFLD) and the potential diagnostic value of LDH for identifying at-risk metabolic associated steatohepatitis (MASH).Methods: This cross-sectional, real-world retrospective study enrolled a total of 1118 obese patients in the department of bariatric surgery at the Second Affiliated Hospital of Anhui Medical University from January 1, 2018, to December 31, 2021. …”
Get full text

Compassionate Use of Omadacycline in a Down Syndrome Pre-Schooler With Critically Ill Atypical Pneumonia Caused by Macrolide-Resistant Mycoplasma Pneumoniae by Wu D, Xie FJ, Wang YJ, Jiang XH, Zhang GL, Zhang H, Zhu YC, Zhang Y, Tang YJ, Lin YL, Xu JX, Zhang JN, Liu BW, Kang K, Gao Y

“…Di Wu,1,* Feng-Jie Xie,2,* Ya-Jun Wang,3,* Xiao-Hui Jiang,1,* Guo-Li Zhang,3,* Hong Zhang,2 Yu-Cheng Zhu,4 Yan Zhang,4 Yu-Jia Tang,1 Yi-Lu Lin,1 Jia-Xi Xu,5 Jia-Ning Zhang,5 Bo-Wen Liu,5 Kai Kang,5 Yang Gao1 1Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 2Department of Critical Care Medicine, The Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang Province, People’s Republic of China; 3Department of Pediatrics, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 4Department of Critical Care Medicine, The Hongxinglong Hospital of Beidahuang Group, Shuangyashan, Heilongjiang Province, People’s Republic of China; 5Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai Kang, Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, Heilongjiang Province, 150001, People’s Republic of China, Tel +86-13904618016, Email janekk79@126.com Yang Gao, Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, 998 Aiying Road, Songbei District, Harbin, Heilongjiang Province, 150027, People’s Republic of China, Tel +86-13045160709, Email gaoyang0312@126.comBackground: Rapid and accurate identification of causative organisms and prompt initiation of pathogen-targeted antibiotics are crucial for managing atypical pneumonia. …”
Get full text

Preparation of Multicore Millimeter-Sized Spherical Alginate Capsules to Specifically and Sustainedly Release Fish Oil by Lina Tao, Panpan Wang, Ting Zhang, Mengzhen Ding, Lijie Liu, Ningping Tao, Xichang Wang, Jian Zhong

Get full text

Risk Factors of Hemophagocytic Lymphohistiocytosis in Adults with Fever of Unknown Origin: A Retrospective Study by Tian F, Xie N, Sun W, Zhang W, Zhang W, Chen J, Ruan Q, Song J

“…Fangbing Tian,1 Nana Xie,1 Wenjin Sun,2 Wencong Zhang,1 Wenyuan Zhang,1 Jia Chen,1 Qiurong Ruan,3,* Jianxin Song1,* 1Department of Infectious Diseases, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Department of Infectious Diseases, Ezhou Central Hospital, Ezhou, People’s Republic of China; 3Institute of Pathology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianxin Song, Department of Infectious Diseases, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China, Email songsingsjx@sina.com Qiurong Ruan, Institute of Pathology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China, Email ruanqiurong@sina.comPurpose: Hemophagocytic lymphohistiocytosis (HLH) is a critical syndrome with a high mortality rate. …”
Get full text

Advancements in Managing Anthracycline-Induced Cardiotoxicity: Insights from Interventional Clinical Trials by Zhao M, Zhang X, Zhou D, Song J

“…Mei Zhao,1 Xiaohong Zhang,1 Dongyang Zhou,2 Junxian Song3– 5 1Department of Pharmacy, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK; 3Department of Cardiology, Peking University People’s Hospital, Beijing, People’s Republic of China; 4Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People’s Hospital, Beijing, People’s Republic of China; 5Center for Cardiovascular Translational Research, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Junxian Song, Department of Cardiology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, People’s Republic of China, Email sjx221@163.comPurpose: Anthracycline-induced cardiotoxicity (AIC) is a significant complication in cancer treatment, impacting long-term health outcomes. …”
Get full text

Extracellular Vesicles in Periodontitis: Pathogenic Mechanisms and Therapeutic Potential by Zhang L, Li X, Zhang B, Li R

“…Ling Zhang,1,* Xiaotong Li,2,* Bin Zhang,3 Ruiji Li4 1School of Nursing, Jining Medical University, Jining, Shandong, 272067, People’s Republic of China; 2Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 3Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272001, People’s Republic of China; 4School of Pharmacy, Jining Medical University, Rizhao, Shandong, 276826, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ruiji Li, School of Pharmacy, Jining Medical University, Xueyuan Road 669, Rizhao, Shandong, 276826, People’s Republic of China, Tel +86-15762380824, Email li-ruiji@mail.jnmc.edu.cnAbstract: Periodontitis is a prevalent yet frequently overlooked oral disease that is linked to a range of systemic conditions. …”
Get full text

Progress in the Management of Retinal Detachment Associated With Morning Glory Syndrome by Wu S, Wang W, Liu L, Wang W, Jiang K, Peng C, Sun H, Zhang J

“…Suping Wu,1 Wenting Wang,2 Lei Liu,3 Wei Wang,2 Keke Jiang,2 Chuanzhi Peng,4 Huixin Sun,1 Jie Zhang2 1Department of Ophthalmology, Binzhou Medical College, Binzhou, Shandong, People’s Republic of China; 2Department of Ophthalmology, Weifang Eye Hospital, Weifang, Shandong, People’s Republic of China; 3Department of Ophthalmology, Guangdong Provincial People’s Hospital, Guangzhou, Guangdong, People’s Republic of China; 4Department of Ophthalmology, Shandong Second Medical University, Weifang, Shangdong, People’s Republic of ChinaCorrespondence: Jie Zhang, Department of Ophthalmology, Weifang Eye Hospital, Weifang, Shandong, People’s Republic of China, Email 15963688601@126.comAbstract: Morning glory syndrome (MGS) is a rare congenital optic disc malformation characterized by a distinctive funnel-shaped optic disc resembling a blooming morning glory flower, typically diagnosed in childhood or adolescence and primarily presenting unilaterally, although bilateral cases have been reported. …”
Get full text

Interaction of an Outflow with Surrounding Gaseous Clouds as the Origin of Late-time Radio Flares in Tidal Disruption Events by Jialun Zhuang, Rong-Feng Shen, Guobin Mou, Wenbin Lu

Get full text

Unraveling the response of the apparent temperature sensitivity of ecosystem respiration to rising temperature by Zhentao Liu, Junguo Liu, Deliang Chen

Get full text

Location optimization of urban fire stations considering the variations in fire service demands: a bi-objective coverage model by Yulong Chen, Jing Yao, Shaohua Wang, Zhizhu Lai, Leying Wu, Guanpeng Dong

Get full text

Problematic Online Video Watching, Boredom Proneness and Loneliness Among First-Year Chinese Undergraduates: A Two-Wave Longitudinal Study by Yan Z, Yang Z, Xu X, Zhou C, Sang Q

“…Zhihao Yan,1,* Zeyang Yang,2,* Xinyuan Xu,3 Chengjun Zhou,2 Qingsong Sang1 1School of Educational Science, Anhui Normal University, Wuhu, People’s Republic of China; 2Department of Psychology, School of Education, Soochow University, Suzhou, People’s Republic of China; 3Foreign Language College, Shanghai Normal University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qingsong Sang, School of Educational Science, Anhui Normal University, Wuhu, People’s Republic of China, Tel +86 13956186006, Email s7210qs1@ahnu.edu.cn Chengjun Zhou, Department of Psychology, School of Education, Soochow University, Suzhou, People’s Republic of China, Tel +86 13057471246, Email zhouchengjun@suda.edu.cnPurpose: While previous cross-sectional studies have investigated the relationship between problematic online video watching and mental health issues, longitudinal studies exploring their bidirectional relationship remain relatively scarce. …”
Get full text

Phase-transition-induced Collapse of Proto-compact Stars and Its Implication for Supernova Explosions by Xu-Run Huang, Shuai Zha, Ming-chung Chu, Evan P. O’Connor, Lie-Wen Chen

Get full text

Randomized radial basis function neural network for solving multiscale elliptic equations by Yuhang Wu, Ziyuan Liu, Wenjun Sun, Xu Qian

Get full text

Drug Clues for the Treatment of Fungal Catheter-Related Bloodstream Infection With Antifungal Lock Therapy by Li X, Yu B, Li H, Liu Z, Fu X, Jiao P, Wang L

“…Xiuyun Li,1 Bing Yu,2 Hui Li,3 Zhirui Liu,4 Xiaohan Fu,1 Ping Jiao,5 Lei Wang6 1Infection and Microbiology Research Laboratory for Women and Children, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250014, People’s Republic of China; 2Medical Affairs Department, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250014, People’s Republic of China; 3Pediatric Department, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250014, People’s Republic of China; 4Faculty of Medicine and Health, The University of Sydney, Camperdown NSW, 2050, Australia; 5Department of Pharmacy, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, 250012, People’s Republic of China; 6School of Pharmaceutical Science @ Institute of Materia Medica. …”
Get full text

YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer by Yangyuan Huang, Shihao Liang, Liping Li, Qingyu Zeng, Bin Li

Get full text

A Novel Pathogenic Splicing Mutation of OFD1 is Responsible for a Boy with Joubert Syndrome Exhibiting Orofaciodigital Spectrum Anomalies, Polydactyly and Retinitis Pigmentosa by Chen L, Zhao MF, Deng HW, Liao M, Fan LL, Zhong QB, Wang J, Li K, Wu ZH, Yin JY

“…Liang Chen,1,* Mei-Fang Zhao,2,* Hui-Wen Deng,1 Min Liao,1 Liang-Liang Fan,2 Qi-Bao Zhong,3 Jun Wang,1 Ke Li,1 Zheng-Hui Wu,4,* Jian-Yin Yin1 1Department of Anesthesiology, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, People’s Republic of China; 2Department of Cell Biology, School of Life Sciences, Central South University, Changsha, 410013, People’s Republic of China; 3Department of Facial Features, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, People’s Republic of China; 4Department of Child Rehabilitation, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-Yin Yin, Department of Anesthesiology, Hunan Provincial Maternal and Child Health Care Hospital. …”
Get full text