Plant-Based Inhibitors of Protein Aggregation by Olha Zhytniakivska, Tanmay Chaturvedi, Mette Hedegaard Thomsen

“…In recent decades, several plant extracts and plant-extracted compounds have shown potential to modulate protein aggregation. An ever-growing body of research on plant-based amyloid inhibitors requires a detail analysis of existing data to identify potential knowledge gaps. …”
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Immunopurification of pathological prion protein aggregates. by Emiliano Biasini, Laura Tapella, Susanna Mantovani, Matteo Stravalaci, Marco Gobbi, David A Harris, Roberto Chiesa

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Targeting protein aggregation for the treatment of neurodegenerative diseases by Qingchao Li, Wei Pan, Jun Zhou, Haiyang Yu, Songbo Xie

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Clearance of protein aggregates during cell division by Shoukang Du, Yuhan Wang, Bowen Chen, Shuangshuang Xie, Kuan Yoow Chan, David C Hay, Ting Gang Chew

“…Protein aggregates are spatially organized and regulated in cells to prevent the deleterious effects of proteostatic stress. …”
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Apple Procyanidins Suppress Amyloid β-Protein Aggregation by Toshihiko Toda, Tadahiro Sunagawa, Tomomasa Kanda, Motoyuki Tagashira, Takuji Shirasawa, Takahiko Shimizu

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Widespread protein aggregation as an inherent part of aging in C. elegans. by Della C David, Noah Ollikainen, Jonathan C Trinidad, Michael P Cary, Alma L Burlingame, Cynthia Kenyon

“…Aberrant protein aggregation is a hallmark of many age-related diseases, yet little is known about whether proteins aggregate with age in a non-disease setting. …”
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Nanoplatforms Targeting Intrinsically Disordered Protein Aggregation for Translational Neuroscience Applications by Chih Hung Lo, Lenny Yi Tong Cheong, Jialiu Zeng

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A Focus on the Link Between Metal Dyshomeostasis, Norepinephrine, and Protein Aggregation by Chiara Bacchella, Andrea Capucciati, Enrico Monzani

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Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration by Vanlalrinchhani Varte, Diego E. Rincon-Limas, Diego E. Rincon-Limas, Diego E. Rincon-Limas

“…This mini review explores the assembly, structure, and cellular functions of TRiC and discusses its involvement in protein aggregation and neurodegenerative diseases. We emphasize the emerging role of CCT2 in modulating the formation of abnormal amyloid aggregates, including amyloid beta, tau, and polyglutamine (polyQ) deposits, which are central to the pathogenesis of various neurological conditions. …”
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Lysine-Targeting Inhibitors of Amyloidogenic Protein Aggregation: A Promise for Neurodegenerative Proteinopathies by Kazuma Murakami, Thi Hong Van Nguyen, Chioko Nagao, Kenji Mizuguchi, Gal Bitan

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Elaboration of molecular glues that target TRIM21 into TRIMTACs that degrade protein aggregates by Marc A. Scemama de Gialluly, Anthony R. Allen, Elijah H. Hayes, Patrick Zhuang, Ralston B. Goldfarb, Amanda N. Farrar, Yuriy Fedorov, Drew J. Adams

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Induction of hepatitis B core protein aggregation targeting an unconventional binding site by Vladimir Khayenko, Cihan Makbul, Clemens Schulte, Naomi Hemmelmann, Sonja Kachler, Bettina Böttcher, Hans Michael Maric

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Native Fold Delay and its implications for co-translational chaperone binding and protein aggregation by Ramon Duran-Romaña, Bert Houben, Paula Fernández Migens, Ying Zhang, Frederic Rousseau, Joost Schymkowitz

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Wheat Protein Aggregation and Disaggregation Behaviors and Their Effects on Dough Rheological Properties and Noodle Qualities by Xiangke YU, Yuanxiao LIU, Jianli WANG, Shaoying LI, Xiaoning WANG, Tingjing ZHANG, Erqi GUAN

“…Finally, the contributions of wheat protein aggregation and disaggregation to dough rheology and noodle quality are comprehensively overviewed and emphatically discussed. …”
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Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation by Rui Fang, Luolan Bai, Bert M. Verheijen, Boyan Li, Kevin Dong, Joao A. Paulo, Mengying Zhou, Yi-Chi Chu, Yuyu Song, Michael Y. Sherman, Steven Gygi, Christine M. Field, Timothy J. Mitchison, Ying Lu

“…Coupling an aggresome adapter to polystyrene beads recapitulates positive size selectivity in transport, while recruiting conventional dynein adapters to protein aggregates perturbs aggresome formation and reverses the size selectivity.…”
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Characterization of the Interaction of Human γS Crystallin with Metal Ions and Its Effect on Protein Aggregation by Reinier Cardenas, Arline Fernandez-Silva, Vanesa Ramirez-Bello, Carlos Amero

“…For HγS crystallin, several equivalent ratios of Cu(II) promote protein aggregation. However, reports on zinc are contradictory. …”
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Self-driving microscopy detects the onset of protein aggregation and enables intelligent Brillouin imaging by Khalid A. Ibrahim, Camille Cathala, Carlo Bevilacqua, Lely Feletti, Robert Prevedel, Hilal A. Lashuel, Aleksandra Radenovic

“…Abstract The process of protein aggregation, central to neurodegenerative diseases like Huntington’s, is challenging to study due to its unpredictable nature and relatively rapid kinetics. …”
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Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders by Ruonan Wang, Zhongyi Jian, Yanlian Yang, Chen Wang, Lanlan Yu, Mingzhan Wang, Chenxuan Wang

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Molecular Mechanisms of Protein Aggregation in ALS-FTD: Focus on TDP-43 and Cellular Protective Responses by Enza Maria Verde, Valentina Secco, Andrea Ghezzi, Jessica Mandrioli, Serena Carra

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Protein‐extending ACTN2 frameshift variants cause variable myopathy phenotypes by protein aggregation by Johanna Ranta‐aho, Kevin J. Felice, Per Harald Jonson, Jaakko Sarparanta, Cédric Yvorel, Ines Harzallah, Renaud Touraine, Lynn Pais, Christina A. Austin‐Tse, Vijay S. Ganesh, Melanie C. O'Leary, Heidi L. Rehm, Michael K. Hehir, Sub Subramony, Qian Wu, Bjarne Udd, Marco Savarese

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