Hand cooling induces changes in the kinetics of oxygen uptake by Louis Finiel, Daria Neyroud, Jean-Philippe Antonietti, Anthony M. J. Sanchez, Fabio Borrani

“…Ten active participants underwent three 8-minute constant work rate exercises (CWR) at ∆25%, with one CWR preceded by hand cooling (2 min at 0 °C, HC) and two consecutive CWR to induced priming effect on the second bout (SB). …”
Get full text

Intraprosthetic Dislocation Following Dual Mobility Total Hip Arthroplasty: A Retrieval Analysis Study by Salar Sobhi, BSc, MD, Alan Kop, MSc, PhD, Moreica Pabbruwe, PhD, Christopher W. Jones, BCom, BEng(Hons), MBBS(Hons), PhD, FRACS, FAOrthA, Michael A. Finsterwald, MD, FMH, FRACS, FAOrthA

“…Of these, 8 (73%) had a documented preceding failed closed reduction, with the remaining 3 revised due to trunnionosis, loosening, and joint instability. …”
Get full text

Care coordination across healthcare systems: development of a research agenda, implications for practice, and recommendations for policy based on a modified Delphi panel by Aneesa Motala, Susanne Hempel, Michelle Wong, Maria Bolshakova, Ning Fu, David Ganz, Sonali Saluja, Timothy Kim, Carolyn Turvey, Kristina Cordasco, Aashna Basu, Tonya Page, Reshma Mahmood, Jenny Barnard, Isomi M Miake-Lye

“…We explored the domains and requirements for care coordination by professionals across healthcare systems and developed an agenda for research, practice and policy.Design The modified Delphi approach convened a 2-day stakeholder panel with moderated virtual discussions, preceded and followed by online surveys.Setting The work addresses care coordination across healthcare systems. …”
Get full text

Mural cell dysfunction contributes to diastolic heart failure by promoting endothelial dysfunction and vessel remodelling by Mandy O. J. Grootaert, Alessandra Pasut, Jana Raman, Steven J. Simmonds, Bram Callewaert, Ümare Col, Mieke Dewerchin, Peter Carmeliet, Stephane Heymans, Elizabeth A. V. Jones

“…Results Db/db mice given 1% salt for 8 weeks developed diastolic dysfunction preceded by capillary density loss, pericyte loss and vessel regression. …”
Get full text

Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration by Aurélie Fessard, Aliki Zavoriti, Natacha Boyer, Jules Guillemaud, Masoud Rahmati, Peggy Del Carmine, Christelle Gobet, Bénédicte Chazaud, Julien Gondin

“…NMES-induced myonuclear accretion was specific to type IIB myofibers and was an early event preceding muscle hypertrophy inasmuch as a mild increase in myofiber cross-sectional area was only observed in response to the long-term NMES training protocol. …”
Get full text

PSMA antibody, humanized PSMA.CAR10.3, or Cetuximab increases prostate cancer localization of NF-κB p50-deficient immature myeloid cells (p50-IMC) and phagocytosis by their macroph... by Mohammad A. Alzubi, Theresa Barberi, Alan D. Friedman

“…Tumor localization is further increased when myelo-depleting 5-fluorouracil precedes p50-IMC administration. Additionally, we find that PSMA Ab, EGFR Ab, or PSMA.CAR10.3 increase in vitro phagocytosis of Myc-CaP cells expressing PSMA or EGFR by p50-IMC-derived macrophages, including in M2-promoting IL-4, which is a component of the immune-suppressive tumor microenvironment. …”
Get full text

Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review by Brijesh Singh Chauhan, Yash Pal Singh

“…Results: We conducted a comprehensive review of the research progress on ANE, focusing on its pharmacological effects on various diseases using animal models, mechanisms of action, and composition, are as not explored in preceding reviews. Additionally, we examined the bioactive ingredients in ANE, highlighting their potential to address significant challenges in mitigating human diseases. …”
Get full text

The utilization of the multimodal immunotherapy for the opsoclonus–myoclonus syndrome can reduce relapses and permanent neurological sequelae by Fang He, Miriam Kessi, Ciliu Zhang, Jing Peng, Fei Yin, Lifen Yang

“…The median age of onset was 15.50 months. Preceding manifestation was present in one patient and two cases had neuroblastoma. …”
Get full text

Beyond averages: dissecting urban-rural disparities in skilled antenatal care utilization in Bangladesh - a conway-maxwell-poisson regression analysis by Md. Muddasir Hossain Akib, Farzana Afroz, Bikash Pal

“…The information regarding the last birth of mothers who delivered within three years preceding the survey has been analyzed. We have applied the Conway-Maxwell-Poisson regression model (CMPRM) to deal with the overdispersion in skilled ANC count data, as this model shows the least AIC compared to the classical negative-binomial regression model (NBRM) and the generalized Poisson regression model (GPRM). …”
Get full text

Cross-Modal Augmented Transformer for Automated Medical Report Generation by Yuhao Tang, Ye Yuan, Fei Tao, Minghao Tang

“…Furthermore, CAT employs a dual-stream decoder that dynamically determines whether the predicted word should be influenced by the retrieved terminology or the preceding sentence. Experimental results demonstrate the effectiveness of the proposed method on two datasets.Clinical impact: This work aims to design an automated framework for explaining medical images to evaluate the health status of individuals, thereby facilitating their broader application in clinical settings.Clinical and Translational Impact Statement: In our preclinical research, we develop an automated system for generating diagnostic reports. …”
Get full text

Exploring the Mediating Role of Multiple Organ Dysfunction in Sepsis-Induced Disseminated Intravascular Coagulation and Its Impact on Worsening Prognosis by Guangjie Wang MD, Chenxiao Hao MD, Sun Yao MD, Yiqin Wang PHD, Zongtao Xu MD, Huiying Zhao MD, Youzhong An MD

“…Initial data comparison preceded logistic regression analysis of mortality factors post-propensity score matching (PSM). …”
Get full text

The antibiotic procurement saga: a long-neglected stewardship target to combat antimicrobial resistance in Pakistan by Shairyar Afzal, Mishal Bajwa, Nabeel Ahmed, Jawaria Jabeen, Mian Shahzeb Haroon, Rana Muhammad Zahid Mushtaq, Zikria Saleem

“…Results The study identified five central themes: (1) The state of antibiotic use in hospitals is characterized by a lack of antibiotic use policy, resulting in mostly empirical and irrational prescribing practices. (2) Medicine availability significantly influences prescribing decisions, often taking precedence over clinical needs. (3) The procurement process, although structured, is flawed owing to rigid adherence to the Standard Medicine List (SML). (4) Rationality in procurement is compromised by disregard for AMR, with decisions driven more by cost and demand than clinical evidence. (5) The clinical acumen of pharmacists is underutilized in procurement due to multifarious barriers. …”
Get full text

Supply Chain Practices and Performance of Institutions: A Case Study of Hotloaf Bakery in Kabale Municipality. by Asiimwe, Elias

“…The study recommends that the process of strategic planning should be given its deserved attention in terms of all the prescribed steps to ensure an efficient supply chain and performance of the organization Hotloaf bakery should set performance targets and the preceding process of strategic planning it is an important aspect of performance management for their organization.…”
Get full text

Comparative survival outcomes of neoadjuvant and adjuvant therapy in patients with T1c, node-negative, triple-negative breast cancer: A population-based analysis by Yi-Zi Zheng, Jia-Qi Ying, Ting-Ting Wu, Yong-Hui Su, Ou-Chen Wang

“…Background: Ongoing discussions persist concerning the precedence of neoadjuvant therapy (NAT) relative to adjuvant therapy (AT) for patients with T1c, node-negative, triple-negative breast cancer (TNBC), and pertinent guidelines for these individuals are absent. …”
Get full text

Tectonometamorphic evolution of a subduction plate interface at the base of the Mirdita Ophiolite (Bajram Curri, northeastern Albania) by Madeline Richter, Kilian Pollok, Kujtim Onuzi, Kamil Ustaszewski

“…The assembly of obducted mantle rocks and metamorphic sole constitutes a plate interface that formed during the intraoceanic subduction stage preceding obduction; we call this a fossil intraoceanic plate interface in this paper. …”
Get full text

A Case of Exacerbation of Chronic Pancreatitis Against the Background of COVID-19 Complicated by Pancreaticopleural Fistula with Enzymatic Pleurisy by I. I. Kotov, I. Yu. Kalinina, A. R. Propp, D. A. Sulim

“…Obviously, this infection can influence the course of the inflammatory process in chronic pancreatitis.This clinical observation presents a rare case of exacerbation of chronic pancreatitis with the formation of a pancreaticopleural fistula with subtotal enzymatic pleurisy on the left, which was preceded by pneumonia caused by SARS-CoV-2 in a 47-year-old man who abused alcohol. …”
Get full text

The Impact of ICT on Student's Academic Performance in Selected Secondary Schools in Kabale District: A Case Study of Katuna Town Council. by Muzahura, Onesmus

“…An attempt to integrate information and communication technologies will be a fruitful and efficient process only if it is preceded by proper planning provided by the Ministry of Education and Sports and the proper provision of resources for schools. …”
Get full text

Determinants of postnatal care service utilization among mothers of Mangochi district, Malawi: a community-based cross- sectional study by Jonas, Sagawa, Allen, Kabagenyi, Godwin, Turyasingura, Saul Eric, Mwale

“…Methods: A community based cross-sectional study was conducted among 600 mothers who gave birth in the past 2 years preceding January 1–31; 2016. A multistage sampling technique was employed to select respondents from nine randomly selected villages in Mangochi district. …”
Get full text

Prevalence and factors associated with adverse pregnancy outcomes in South Africa: Evidence from the 2016 Demographic and Health Survey by L Mpolokeng, A Musekiwa

“…There were 8 514 women of reproductive age, of whom 41.2% had fallen pregnant during the 5-year period preceding the survey. The majority (70.9%) were of age 20 - 34 years, 78% had secondary education, 61.6% were unemployed, 65% were from urban areas, and more than 40% of these women were currently living with a man, while 51.5% reported that they had never been in a union. …”
Get full text

Under-five mortality and its associated factors in sub-Saharan Africa: a multilevel analysis of recent demographic and health surveys data based on Bayesian approach by Atalay Liknaw Birhanie, Zemenu Tadesse Tessema, Bekalu Endalew, Koku Sisay Tamirat

“…Whereas, being female (AOR = 0.86; 95%CrI: 0.82, 0.91), preceding birth interval of 24–35 months (AOR = 0.61; 95%CrI: 0.57, 0.65) and above 36 months (AOR = 0.48; 95%CrI: 0.43, 0.49), ANC visit (AOR = 0.80; 95%CrI: 0.74 0.86), contraceptive use (AOR = 0.57; 95%CrI: 0.53, 0.61), were preventive factors of under-five mortality. …”
Get full text