Kiai sebagai Konselor: Pendekatan Spiritual dalam Mereduksi Panic Attack Santri di Pesantren by Shofa Aulia Kumala

“…The symptoms were excessive anxiety, restlessness, and difficulty in social interaction. Kiai played an essential role in relieving panic attacks through dhikr and prayer, Islamic reflection therapy, counseling based on Al-Qur'an values, and an individual approach. …”
Get full text

Oxidative stress in viral hepatitis by Huseyin Erdal, Hacer Ozlem Kalayci

“…Accumulating evidence suggests that oxidative stress (OS) plays a pivotal role in the pathogenesis and progression of viral hepatitis. …”
Get full text

Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles by Yuqi Song, Fengrui Liang, Weikun Tian, Erin Rayhill, Liping Ye, Xinghan Tian

“…Additionally, miRNA variability in MSC-EVs presents challenges due to the diverse roles of miRNAs play in regulating gene expression and cell behavior. …”
Get full text

Oxidative impact on lipoprotein structure: Insights from dynamic light scattering by Nickolette Kong, Natalia Penaloza, Gustavo Agreda, Angela B. Nguyen, Joseph Gutheinz, Alison Tran, Nhi Nguyen, Tuong Vi Ho, Ana Marin, Birgit Mellis, Richa Chandra

“…Here it is demonstrated that dynamic light scattering (DLS) is sensitive and effective at measuring variation in lipoprotein size distributions following oxidative damage caused by peroxidation and nitration—two common physiological processes that play dual roles in both normal and pathogenic states. …”
Get full text

Overexpression of metalloproteinase PAPPA accelerates cancer progression and correlates with immune cell infiltration in gastric cancer: insights from bioinformatics and in vitro i... by Shiya Yu, Shiyao Zheng, Jinwei Qiu, Hongming Lin, Xiaojuan Yu, Huiyan Chen, Junhong Wu, Weihang Wu, Jiong Chen, Yongyuan Chen, Jianwei Chen, Hu Zhao, Yu Wang

“…Pregnancy-associated plasma protein-A(PAPPA) is thought to play an important role in the occurrence and progression of cancer, yet its significance in the development of GC has not been reported. …”
Get full text

EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer by Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

“…Results We found that NAT10 is highly expressed in CRC samples and plays a pro-oncogenic role. NAT10 knockdown led to PI3K-AKT pathway inactivation, thereby inhibiting CRC progression. …”
Get full text

Integrated microbiome, transcriptome and metabolome insight into the alleviating mechanisms of sheep milk in a DSS-induced colitis mouse model by Wenna Yao, Ruilin Du, Shuo Yan, Teligun Bao, Huimin Zhang, Fang Yang, Yue Xue, Yulong Zhao, Siqin Bao, Xihe Li, Yongli Song

“…However, it is unclear whether gut microbes and metabolites play a role in preventing and treating UC in sheep milk. …”
Get full text

Clinical characteristics, metastasis patterns, and treatment outcomes of HER2-low breast cancer by Maria Elena Lacruz, Saskia Thies, Andrea Schmidt-Pokrzywniak, Ian Wittenberg, Tobias Engler, Fabian Reinwald, Monika Klinkhammer-Schalke, Sylke Ruth Zeissig, Bianca Franke, Kerstin Weitmann, Atanas Ignatov

“…HER2-low, characterized by low HER2 expression without gene amplification, recently gained attention. While new therapies are promising, its clinical significance remains unclear. …”
Get full text

RIPK1 in necroptosis and recent progress in related pharmaceutics by Kunhou Yao, Zhihao Shi, Fengya Zhao, Cong Tan, Yixin Zhang, Hao Fan, Yingzhe Wang, Xingwang Li, Jun Kong, Qun Wang, Dingxi Li

“…In this paper, we outline the pathways of necroptosis and the role RIPK1 plays in them and suggest that targeting RIPK1 in therapy may help to inhibit multiple cell death pathways.…”
Get full text

Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression by Agata Ossolińska, Patrycja Marta, Filip Huzarski, Gabriela Ferfecka, Klaudia Pawełek, Lucyna Stolarska, Magdalena Rosa-Bończak, Natalia Morawiecka, Olivier Carlton, Weronika Kłosowicz

“… Physical activity plays a critical role in promoting physical and mental health, positively influencing the prevention of non-communicable diseases (NCDs) and enhancing brain function. …”
Get full text

Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

“…Abstract Sphingolipid, ceramide for example, plays an essential role in regulating cancer cell death. …”
Get full text

Antibacterial activity of jamblang leaf ethanol extract (Syzygium cumini) against the growth of Propionibacterium acnes by Maria Fransiska Priska Yulianti, Anita Lidesna Shinta Amat, Regina Marvina Hutasoit, Prisca Deviani Pakan

“… Background: Propionibacterium acnes is a bacterium found on the skin that plays a significant role in acne vulgaris. The inappropriate use of antibiotics can lead to resistance, necessitating the search for alternative therapies from plants with high antibacterial potential. …”
Get full text

A SYSTEMATIC ANALYSIS OF AI-EMPOWERED EDUCATIONAL TOOLS DEVELOPED IN INDIA FOR DISABLED PEOPLE by Shivani, Monika Gupta, Satinder Bal Gupta

“… Artificial Intelligence (AI) plays a multifaceted role in educating impaired people and has significantly enhanced the learning experience of disabled students. …”
Get full text

RTEL1 is upregulated in gastric cancer and promotes tumor growth by Chunyu Yang, Suzeng Wang, Ge Gao, Peiwen Xu, Mengyuan Qian, Yuan Yin, Surui Yao, Zhaohui Huang, Zehua Bian

“…These findings suggest that RTEL1 plays a critical role in GC tumorigenesis and could be a promising target for the therapy and prognosis of GC.…”
Get full text

New Prospects of Cytoprotection in the Treatment and Prevention of Gastric and Intestinal Diseases (Resolution of an Expert Council and Literature Review) by A. I. Martynov, A. A. Sheptulin, I. V. Mayev, A. N. Kazyulin, A. Ye. Karateev, A. V. Melekhov, L. K. Pal’gova, K. L. Raikhel’son

“…In the treatment of gastroesophageal reflux disease, Rebamipide is recommended for patients refractory to therapy with proton pump inhibitors (PPIs) and for those with non-acid reflux. …”
Get full text

Akinetopsia: a systematic review on visual motion blindness by Johanna L. Browne, Lydia Krabbendam, Jan Dirk Blom, Jan Dirk Blom, Jan Dirk Blom

“…In contrast to earlier studies, we found a greater prevalence of right-hemispheric afflictions in clinical cases, suggesting that the right area V5/MT plays a more dominant role in motion perception. …”
Get full text

Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic by Ziwei Cui, Peng Wang, Weiyue Gao

“…Dysbiosis of the subgingival microbiome—characterized by an increase in pathogenic bacteria such as Porphyromonas gingivalis, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans—plays a pivotal role in the initiation and progression of periodontitis. …”
Get full text

Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride by Reena Deshmukh, Manisha Jaiswal, Anshita Shukla, Umesh Patil, Mukesh Sharma

“…Since there are currently few therapy options for AD, more alternatives are required. …”
Get full text

Comparative analysis of dominant gut microbiota in Inflammatory Bowel Disease patients and healthy individuals: A case-control study by Alireza Ahmadi, Ebrahim Kouhsari, Shabnam Razavi, Nima Mohamadzadeh, Sima Besharat, Mohammad Ali Vakili, Taghi Amiriani

“…These findings suggest that gut microbiota dysbiosis may play a critical role in IBD pathogenesis. The identification of specific bacterial imbalances provides a foundation for developing microbiota-based therapies, such as probiotics, prebiotics, and fecal microbiota transplantation, as potential interventions for restoring microbial balance and mitigating disease progression. …”
Get full text

Relationship between dietary intake and atherogenic index of plasma in cardiometabolic phenotypes: a cross-sectional study from the Azar cohort population by Shirin Soheilifard, Elnaz Faramarzi, Reza Mahdavi

Get full text