Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates by Jersley D. Chirawurah, Felix Ansah, Samuel Blankson, Bridget Adikah, Silas Nkansah Yeboah, Lucas Amenga-Etego, Gordon A. Awandare, Yaw Aniweh

“…Abstract Gossypol has demonstrated significant antimalarial activity against chloroquine-resistant and susceptible Plasmodium falciparum parasites. However, data on its potency in clinical isolates of P. falciparum remains limited. …”
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Assessment of different genotyping markers and algorithms for distinguishing Plasmodium falciparum recrudescence from reinfection in Uganda. by Mwesigwa, Alex, Golumbeanu, Monica, Jones, Sam, Cantoreggi, L. Sara, Musinguzi, Benson, Nankabirwa, I. Joaniter, Bikaitwoha, Everd Maniple, Kalyango, N. Joan, Karamagi, Charles, Plucinski, Mateusz, Nsobya, L. Samuel, Nsanzabana, Christian, Byakika-Kibwika, Pauline

Subjects: “…Plasmodium falciparum…”
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TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected with Plasmodium berghei ANKA by Elizabeth S. Fernandes, Carolina X. L. Brito, Simone A. Teixeira, Renato Barboza, Aramys S. dos Reis, Ana Paula S. Azevedo-Santos, Marcelo Muscará, Soraia K. P. Costa, Claudio R. F. Marinho, Susan D. Brain, Marcos A. G. Grisotto

“…C57BL/6 mice received 105 red blood cells infected with Plasmodium berghei ANKA intraperitoneally. Noninfected mice were used as controls. …”
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The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum by Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke

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In Vivo Antiplasmodial Activity of Terminalia mantaly Stem Bark Aqueous Extract in Mice Infected by Plasmodium berghei by Mariscal Brice Tchatat Tali, Cedric Derick Jiatsa Mbouna, Lauve Rachel Yamthe Tchokouaha, Patrick Valere Tsouh Fokou, Jaures Marius Tsakem Nangap, Rodrigue Keumoe, Alvine Ngoutane Mfopa, Issakou Bakarnga-via, Raceline Gounoue Kamkumo, Fabrice Fekam Boyom

“…The aqueous extract from the stem bark of T. mantaly (Tmsbw) was the most potent (IC50=0.809 μg/mL) and was further assessed for acute toxicity and efficacy in Plasmodium berghei-infected mice. Tmsbw was safe in mice with a median lethal dose (LD50) higher than 2000 mg/kg of body weight. …”
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An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase by Lois Kwane Kyei, Edward Ntim Gasu, Gilbert Boadu Ampomah, Jehoshaphat Oppong Mensah, Lawrence Sheringham Borquaye

“…The Plasmodium falciparum dihydrofolate reductase (PfDHFR) and dihydroorotate dehydrogenase (PfDHODH) are essential for Plasmodium falciparum growth and development, and have been validated as targets for the development of new antimalarial agents. …”
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Ruptura esplénica espontánea como complicación en la malaria aguda grave por plasmodium falciparum by José Miguel Rodríguez Perón, Lázaro Ricardo López Hernández, Roberto Columbié González

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The Potential Role of Gymnema inodorum Leaf Extract Treatment in Hematological Parameters in Mice Infected with Plasmodium berghei by Sakaewan Ounjaijean, Suriyan Sukati, Voravuth Somsak, Orawan Sarakul

“…Hence, this study aimed to determine the efficacy of the Gymnema inodorum leaf extract (GIE) on hematological alteration in Plasmodium berghei infection in mice. Groups of ICR mice were infected intraperitoneally with parasitized red blood cells of P. berghei ANKA (PbANKA). …”
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Contrasting vector competence of three main East African Anopheles malaria vector mosquitoes for Plasmodium falciparum by Prisca A. Kweyamba, Lorenz M. Hofer, Ummi A. Kibondo, Rehema Y. Mwanga, Rajabu M. Sayi, Fatuma Matwewe, Dickson W. Lwetoijera, Mgeni M. Tambwe, Sarah J. Moore

“…., and An. arabiensis mosquitoes towards local isolates of Plasmodium falciparum infection. Mosquito feeding assays using gametocytaemic blood from local donors revealed significant differences in both prevalence and intensity of oocyst and sporozoite infections among the three vectors. …”
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Exploring the Infectious Drug Target Glutathione S-Transferase in Plasmodium falciparum with the Inhibitory Potential of Azadirachta indica Phytocompounds by Esam S. Al-Malki

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Anti-Malarial Effects of Five Traditional Nigerian Medicinal Plant Extracts on Plasmodium Berghei-Infected Rats by Ugochukwu Vincent, Igbokwe, Ejike, Daniel Eze, Moses Dele, Adams, Karimah Mohammed, Rabiu, Iliya, Ezekiel, Prisca Ojochogu, Ajeka, Peace Ogechukwu, Okpara

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Plasmodium Falciparum Genetic Diversity and Multiplicity of Infection Among Asymptomatic and Symptomatic Malaria-Infected Individuals in Uganda. by Mwesigwa, Alex, Ocan, Moses, Cummings, Bryan, Musinguzi, Benson, Kiyaga, Shahid, Kiwuwa, Steven M., Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Karamagi, Charles, Nankabirwa, Joaniter I., Nsobya, Samuel L., Byakika‐Kibwika, Pauline

“…Plasmodium falciparum (P. falciparum) remains a significant public health challenge globally, especially in sub-Saharan Africa (SSA), where it accounts for 99% of all malaria infections. …”
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Genetic diversity and population structure of Plasmodium falciparum across areas of varied malaria transmission intensities in Uganda. by Mwesigwa, Alex, Tukwasibwe, Stephen, Cummings, Bryan, Kawalya, Hakiimu, Kiyaga, Shahiid, Okoboi, Stephen, Castelnuovo, Barbara, Bikaitwoha, Everd Maniple, Kalyango, Joan N., Nsobya, Samuel L., Karamagi, Charles, Byakika‑Kibwika, Pauline, Nankabirwa, Joaniter I.

Subjects: “…Plasmodium falciparum…”
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

Subjects: “…Plasmodium…”
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Two Imported Malaria Cases with Delayed Response to Treatment in Hatay by Tuğba Kaya, Mehmet Çabalak, Gülnaz Çulha, Ceren Ünal

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Myocarditis in malaria—current evidence and future directions: a literature review by Gbolahan Olatunji, Emmanuel Kokori, Ikponmwosa Jude Ogieuhi, Olumide Akinmoju, Oluwatobi Omoworare, Doyin Olatunji, David Timilehin Isarinade, God-dowell O. Odukudu, Israel Charles Abraham, Samuel Owolabi, Jamil Nasrallah, Emmanuel Egbunu, Babafemi Oluwadarasimi Jaiyeoba, Ismaila Ajayi Yusuf, Olawale Olanisa, Nicholas Aderinto

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N-Terminal Plasmodium vivax Merozoite Surface Protein-1, a Potential Subunit for Malaria Vivax Vaccine by Fernanda G. Versiani, Maria E. Almeida, Luis A. Mariuba, Patricia P. Orlandi, Paulo A. Nogueira

“…The human malaria is widely distributed in the Middle East, Asia, the western Pacific, and Central and South America. Plasmodium vivax started to have the attention of many researchers since it is causing diseases to millions of people and several reports of severe malaria cases have been noticed in the last few years. …”
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Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. by Deirdre Larkin, Bas de Laat, P Vince Jenkins, James Bunn, Alister G Craig, Virginie Terraube, Roger J S Preston, Cynthia Donkor, George E Grau, Jan A van Mourik, James S O'Donnell

“…Plasmodium falciparum infection results in adhesion of infected erythrocytes to blood vessel endothelium, and acute endothelial cell activation, together with sequestration of platelets and leucocytes. …”
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Plasmodium falciparum Merozoite Surface Proteins Polymorphisms and Treatment Outcomes among Patients with Uncomplicated Malaria in Mwanza, Tanzania by Karol J. Marwa, Eric Lyimo, Eveline T. Konje, Anthony Kapesa, Erasmus Kamugisha, Göte Swedberg

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Machine learning methods for predicting essential metabolic genes from Plasmodium falciparum genome-scale metabolic network. by Itunuoluwa Isewon, Stephen Binaansim, Faith Adegoke, Jerry Emmanuel, Jelili Oyelade

“…Identifying these genes, especially in complex organisms like Plasmodium falciparum, which causes malaria, is challenging due to the cost and time associated with experimental methods. …”
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