Investigating the Presence of Falsified and Poor-Quality Fixed-Dose Combination Artemether-Lumefantrine Pharmaceutical Dosage Forms in Kumasi, Ghana by Simon Nyarko, Kwabena Ofori-Kwakye, Raphael Johnson, Noble Kuntworbe, Denis Dekugmen Yar

“…Artemether-lumefantrine (AL) is a highly effective and commonly used Artemisinin-based Combination Therapy (ACT) for treating uncomplicated malaria caused by Plasmodium falciparum, including drug-resistant strains. …”
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COVID-19 in patients presenting with malaria-like symptoms at a primary healthcare facility in Accra, Ghana. by Issabella Asamoah, Mildred Adusei-Poku, Priscilla Vandyck-Sey, Allen Steele-Dadzie, Atta Senior Kuffour, Albert Turkson, Ivy Asantewaa Asante, Kantanka Addo-Osafo, Quaneeta Mohktar, Bright Adu, Yaw A Afrane, Kwamena W C Sagoe

“…After consent was obtained from study patients, two to three millilitres of whole blood, nasopharyngeal and oropharyngeal swab samples, were collected for screening of Plasmodium falciparum using malaria rapid diagnostic test, microscopy and nested PCR, and SARS-CoV-2 using SARS-CoV-2 antigen test and Real-time PCR, respectively. …”
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In Vitro Antiplasmodial, Cytotoxicity, and Antioxidant Activities of Lophira lanceolata (Ochnaceae): A Cameroonian Plant Commonly Used to Treat Malaria by Mounvera Abdel Azizi, Noumedem Anangmo Christelle Nadia, Yamssi Cedric, Gamago Nkadeu Guy-Armand, Ngouyamsa Nsapkain Aboubakar Sidiki, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne

“…It tested in vitro the extracts against Plasmodium falciparum 3D7 and multiresistance Dd2. Macrophage cell lines (RAW 264.7 cells) and red blood cells were used for cytotoxicity tests. …”
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Antimalarial Activity of Extract and Fractions of Sauropus androgynus (L.) Merr. by Wiwied Ekasari, Dwi Fatmawati, Siti M. Khoiriah, Wenda A. Baqiuddin, Hawi Q. Nisa, Adinda A. S. Maharupini, Tutik S. Wahyuni, Rice D. Oktarina, Eko Suhartono, Ram K. Sahu

“…Based on genus and chemotaxonomic approaches, as well as in vitro testing of Plasmodium falciparum, leaves of S. androgynus are presumed to have an active compound content as an antimalarial. …”
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The Effectiveness of Varying Combination Ratios of A. cordifolia and M. indica against Field and Laboratory Strains of P. falciparum In Vitro by Yakubu Jibira, Elizabeth Cudjoe, Frederick M. Tei-Maya, Benjamin Ayensu, Linda E. Amoah

“…Drug resistance in malaria is a global problem, with reports of Plasmodium parasites resistant to the current first-line antimalarial drug, artemisinin, expanding from Southeast Asia to Africa. …”
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Application of a targeted amplicon sequencing panel to screen for insecticide resistance mutations in Anopheles darlingi populations from Brazil by Holly Acford-Palmer, Alice O. Andrade, Jody E. Phelan, Rosa A. Santana, Stefanie C. P. Lopes, Jansen F. Medeiros, Taane G. Clark, Maisa S. Araujo, Susana Campino

“…In South America, Anopheles darlingi is the primary malaria vector and is responsible for the majority of Plasmodium species transmission. However, little is known about the molecular markers associated with insecticide resistance in this species. …”
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Malaria exposure remodels the plasma proteome of Ghanaian children by Aisha M. Mohammed, Charles Ochieng’ Olwal, Andrea Fossati, Nancy K. Nyakoe, Jacqueline M. Fabius, Martin Gordon, Benjamin J. Polacco, Danielle L. Swaney, Gordon A. Awandare, Nevan J. Krogan, Mehdi Bouhaddou, Yaw Bediako

“…Abstract Background Malaria, caused by Plasmodium falciparum, remains a major public health burden causing ~ 200 million deaths annually, especially among children. …”
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Screening chimique, activités antioxydante et antiplasmodiale des extraits d’écorces de tronc d’Enantia olivacea Robyns & Ghesq (Annonaceae), une plante utilisée par les bonobo... by Papy Kunyima, Nseu B Mbomba, Mulavwa Habari, N Lami, Tshimankinda Mpiana, Musuyu Muganza

“…L’activité antiplasmodiale in vitro a été réalisée sur une souche clinique de Plasmodium falciparum. Les résultats obtenus ont montré la présence des flavonoïdes, des leucoanthocyanes, des tanins galliques, des alcaloïdes et des coumarines. …”
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Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy by Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi, Francesco Saccoliti

“…<i>Plasmodium</i>, <i>Leishmania</i>, and <i>Trypanosoma</i> parasites are responsible for infectious diseases threatening millions of people worldwide. …”
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Theoretical Investigation of the Structural, Spectroscopic, Electronic, and Pharmacological Properties of 4-Nerolidylcathecol, an Important Bioactive Molecule by Renyer A. Costa, Earle Silva A. Junior, Jaqueline de A. Bezerra, Josiana Moreira Mar, Emerson S. Lima, Maria Lucia B. Pinheiro, Diego V. C. Mendonça, Guilherme Braule P. Lopes, Adjane Dalvana S. Branches, Kelson M. T. Oliveira

“…Molecular docking calculations with DNA topoisomerase I-DNA complex (TOPO-I), glyceraldehyde 3-phospate dehydrogenase (GAPDH), and Plasmodium falciparum lactate dehydrogenase (PfLDH) showed binding free energies of −6.3, −6.5, and −7.6 kcal/mol, respectively, which indicates that 4NRC is a good competitive inhibitor for these enzymes.…”
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Multiple hosts, multiple impacts: the role of vertebrate host diversity in shaping mosquito life history and pathogen transmission by Vantaux, Amélie, Moiroux, Nicolas, Dabiré, Kounbobr Roch, Cohuet, Anna, Lefèvre, Thierry

“…Our study investigated the effects of 3-4 consecutive blood meals from one of four vertebrate species (human, cattle, sheep, or chicken) on several fitness traits, including mosquito feeding rate, blood meal size, susceptibility to wild isolates of Plasmodium falciparum, survival, fecundity, F1 offspring development time, and size. …”
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Effects on maternal and pregnancy outcomes of first-trimester malaria infection among nulliparous women from Kenya, Zambia, and the Democratic Republic of the Congo. by Sequoia I Leuba, Daniel Westreich, Carl L Bose, Andrew F Olshan, Steve M Taylor, Antoinette Tshefu, Adrien Lokangaka, Waldemar A Carlo, Elwyn Chomba, Musaku Mwenechanya, Edward A Liechty, Sherri L Bucher, Osayame A Ekhaguere, Fabian Esamai, Paul Nyongesa, Saleem Jessani, Sarah Saleem, Robert L Goldenberg, Janet L Moore, Tracy L Nolen, Jennifer Hemingway-Foday, Elizabeth M McClure, Marion Koso-Thomas, Richard J Derman, Matthew Hoffman, Steven R Meshnick, Melissa Bauserman

“…<h4>Methods</h4>In a convenience sample of women from the ASPIRIN (Aspirin Supplementation for Pregnancy Indicated risk Reduction In Nulliparas) trial in Kenya, Zambia, and the Democratic Republic of the Congo, we tested for first-trimester Plasmodium falciparum infection using quantitative polymerase chain reaction. …”
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Synthesis, Antimalarial Activity and Molecular Dynamics Studies of Pipecolisporin: A Novel Cyclic Hexapeptide with Potent Therapeutic Potential by Nety Kurniaty, Taufik Muhammad Fakih, Rani Maharani, Unang Supratman, Ace Tatang Hidayat, Nurhidanatasha Abu Bakar, Xiaoshuang Wei

“…Malaria, caused by <i>Plasmodium</i> species and transmitted by <i>Anopheles</i> mosquitoes, continues to pose a significant global health threat. …”
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Asymptomatic malaria parasitaemia and seizure control in children with nodding syndrome; a cross-sectional study by Charles R J C Newton, Albert Ningwa, Kevin Marsh, Richard Idro, Rodney Ogwang, Ronald Anguzu, Pamela Akun, Edward Kayongo

“…Objective Plasmodium falciparum is epileptogenic and in malaria endemic areas, is a leading cause of acute seizures. …”
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Spring reproductive success influences autumnal malarial load in a passerine bird by Pigeault, Romain, Cozzarolo, Camille-Sophie, Wassef, Jérôme, Gremion, Jérémy, Bastardot, Marc, Glaizot, Olivier, Christe, Philippe

“…Here, we monitored the parasitemia of two haemosporidian parasites – Plasmodium relictum (lineage SGS1) and P. homonucleophilum (lineage SW2) – in two wild populations of great tits (Parus major) in Switzerland over three years, to characterize their dynamics. …”
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Effect of Malaria and Schistosoma mansoni Coinfection on Selected Biochemical Profiles among Patients Attending Selected Health Institutions at Dembiya, Northwest Ethiopia by Wagaw Abebe, Wossenseged Lemma, Yalewayker Tegegne, Amare Mekuanint, Abebe Yenesew, Adane Derso

“…Schistosoma mansoni was detected in stool samples using the wet mount and the Kato Katz method. To detect Plasmodium, both thick and thin blood films were prepared and stained with Giemsa. …”
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Malaria and Geohelminthiasis Coinfections in Expectant Women: Effect on Maternal Health and Birth Outcomes in a Malaria Endemic Region in Kenya by Wekesa Antony Wanyonyi, Chrispinus Siteti Mulambalah, David H. Mulama, Elizabeth Omukunda, Darwin Injete Siteti

“…Parasites identified were Plasmodium falciparum, P. malariae, P. ovale, Ascaris lumbricoides, Necator americanus, Enterobius vermicularis, and Schistosoma mansoni. …”
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Quantifying the potential value of entomological data collection for programmatic decision-making on malaria control in sub-Saharan African settings by Nora Schmit, Hillary M. Topazian, Matteo Pianella, Giovanni D. Charles, Peter Winskill, Penelope A. Hancock, Ellie Sherrard-Smith, Katharina Hauck, Thomas S. Churcher, Azra C. Ghani

“…Methods This study quantified the monetary value of information provided by entomological data collection for programmatic decision-making using a mathematical model of Plasmodium falciparum transmission. The 3-year impact and cost of various intervention packages was simulated in different sub-Saharan African settings, including combinations of scaling-up insecticide-treated nets (ITN), switching to next-generation ITNs, and a treatment and prevention package. …”
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Experiences, perceptions and ethical considerations of the malaria infection study in Thailand by Bhensri Naemiratch, Natinee Kulpijit, Supanat Ruangkajorn, Nicholas P. J. Day, Jetsumon Prachumsri, Phaik Yeong Cheah

“…The Malaria Infection Study in Thailand (MIST) involves deliberate infection of healthy volunteers with Plasmodium vivax malaria parasites, and the assessment of the efficacy of potential vaccine and drug candidates in order to understand acquired protection against malaria parasites. …”
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Magnitude of urban malaria and its associated risk factors in Damboya town, Kambata zone, Central Ethiopia by Biruk Mulachew, Temesgen Bezuayehu, Solomon Asnake

“…Result: The prevalence of malaria was 5 % (20, 95 % CI: 3–7), Plasmodium vivix account for 14 (61.9 %) of the infection. …”
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