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181
Concurrent Infection with Dengue and Malaria: An Unusual Presentation
Published 2013-01-01“…Here, we present a case of a young male returning from a dengue endemic area who tested positive for the virus along with Plasmodium vivax and Plasmodium falciparum. In view of the severity of coinfection (Epelboin et al., 2012), overlapping symptoms, and a challenging obscurity of diagnosis, a multidimensional diagnostic approach is suggested.…”
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182
Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins
Published 2023-12-01“…Screening of the antiplasmodial activities of UT harmiquins against erythrocytic stages of the Plasmodium life cycle identified CQ-based UT harmiquine 12 as a novel antiplasmodial hit because it displayed low IC50 values in the submicromolar range against CQ-sensitive and resistant strains (IC50 0.06 ± 0.01, and 0.19 ± 0.02 μmol L−1, respectively), and exhibited high selectivity against Plasmodium, compared to mammalian cells (SI = 92).…”
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183
Antimalaria Effect of the Ethanolic Stem Bark Extracts of Ficus platyphylla Del
Published 2011-01-01“…The antimalarial effect of the ethanolic stem bark extract of Ficus platyphylla Del was evaluated against Plasmodium berghei infection in mice. Nontreated, experimental control mice died of fulminant parasitemia from day 7 to 9 post-infection but mice treated with the extract at 300 mg/kg showed markedly reduced parasitaemia bouts of 43.50% and a mean survival time of 28 days postinfection. …”
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184
Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger
Published 2019-01-01“…Transfusional malaria is an accidental transmission of Plasmodium via a blood transfusion. Its magnitude is underestimated and very little data on the assessment of this risk are available in Niger. …”
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185
Ecotope-Based Entomological Surveillance and Molecular Xenomonitoring of Multidrug Resistant Malaria Parasites in Anopheles Vectors
Published 2014-01-01“…The emergence and spread of multidrug resistant (MDR) malaria caused by Plasmodium falciparum or Plasmodium vivax have become increasingly important in the Greater Mekong Subregion (GMS). …”
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186
The Burden of Asymptomatic Malaria Infection in Children in Sub-Saharan Africa: A Systematic Review and Meta-Analysis Exploring Barriers to Elimination and Prevention
Published 2025-02-01“…Subgroup analysis showed significant regional and diagnostic tool differences in asymptomatic Plasmodium infection. Conclusion The findings of this study revealed a high prevalence of asymptomatic plasmodium infection in children with significant regional variations. …”
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187
Artemether/Lumefantrine for the Treatment of P. malariae in a Patient on Hemodialysis
Published 2019-01-01“…The combination of artemether/lumefantrine is indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria. There have been no clinical trials to assess the efficacy of this medication in patients with renal impairment. …”
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188
Development of malaria diagnosis with convolutional neural network architectures: a CNN-based software for accurate cell image analysis.
Published 2025-01-01“…The results of the study reveal that it is effective in improving the accuracy of cell images containing Plasmodium. In addition, a software that predicts whether cell images are noisy or not has been developed. …”
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189
Severe Malaria in an Adult Patient from Low-Endemic Area in Flores Island, East Nusa Tenggara
Published 2023-01-01“…Malaria is an infection caused by protozoa of the genus Plasmodium, commonly found in tropical and subtropical regions worldwide. …”
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190
Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection
Published 2013-01-01“…Antibody responses directed against Plasmodium antigens were not significantly affected by praziquantel treatment nor were levels of allergen specific responses. …”
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191
Prevalence of malaria and associated factors among febrile children under 15 years at Bududa General Hospital, Eastern Uganda
Published 2025-02-01“…Among the children who tested positive for malaria, 98 (88.3%) had Plasmodium falciparum, 11 (9.9%) had Plasmodium malariae, and (1.8%) had Plasmodium ovale infection. …”
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192
The Host Genetic Diversity in Malaria Infection
Published 2012-01-01“…Populations exposed to Plasmodium infection develop genetic mechanisms of protection against severe disease. …”
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193
Recent Trends in Malaria Vaccine Research Globally: A Bibliometric Analysis From 2005 to 2022
Published 2024-01-01“…This necessitates more international efforts to improve the vaccines’ effectiveness considering different Plasmodium species.…”
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194
The Potential use of a Curcumin-Piperine Combination as an Antimalarial Agent: A Systematic Review
Published 2021-01-01“…The selected articles discussed their antioxidant, anti-inflammatory, and antiapoptosis properties, as well as their mechanism of action against Plasmodium species. Curcumin is a potent antioxidant, damages parasite DNA, and may promote an immune response against Plasmodium by increasing reactive oxygen species (ROS), while piperine is also a potent antioxidant that potentiates the effects of curcumin. …”
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195
Improving Accuracy of Malaria Diagnosis in Underserved Rural and Remote Endemic Areas of Sub-Saharan Africa: A Call to Develop Multiplexing Rapid Diagnostic Tests
Published 2020-01-01“…Clinical infection with malaria, caused by parasites of the genus Plasmodium, is considered a serious medical condition with the potential to become a life-threatening emergency. …”
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196
Nutritional Status of a Group of Children Under Five Suffering from Malaria in a Timor Leste District
Published 2011-03-01“…A medical history demographic, socioeconomic and Plasmodium type data was obtained. <br /><strong>Results:</strong> 254 children (58.4%) were in the group from 2 to 4 years old. …”
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197
Chemical Constituents of the Bark of Zanthoxylum gilletii (Rutaceae) and Their In Vitro Antiplasmodial and Molecular Docking Studies
Published 2022-01-01“…Furthermore, all the compounds have been evaluated in silico for their ability to inhibit the Plasmodium falciparum dihydroorotate dehydrogenase 5TBO. …”
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198
Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease
Published 2025-01-01“…Abstract Mosquitoes are responsible for the transmission of numerous pathogens, including Plasmodium parasites, arboviruses and filarial worms. …”
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199
Malaria Microscopy Competency in the Subnational Verification, China: Implications for Malaria Elimination and the Prevention of Malaria Reestablishment
Published 2022-01-01“…Specifically, five provincial microscopist representatives and ten county-level representatives were assessed in each of previously endemic provinces on qualitative identification (Plasmodium positive or negative) and Plasmodium species identification using standard slides from the National Malaria Diagnosis Reference Laboratory. …”
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200
Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits
Published 2017-01-01“…In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the parasite lactate dehydrogenase (pLDH) method. …”
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