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5421
E46K α-Synuclein Mutation Fails to Promote Neurite Outgrowth by Not Inducing Cdc42EP2 Expression, Unlike Wild-Type or A53T α-Synuclein in SK-N-SH Cells
Published 2024-12-01“…Conclusions: Our findings suggest that WT and mutant α-syn are linked to Cdc42EP2 production in neuritogenesis, implying α-syn involvement in the physiological function of axon growth and synapse formation. …”
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5422
Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes: potential targets for neural repair in neurological diseases
Published 2025-12-01“…The exchange of information and materials between organelles plays a crucial role in regulating cellular physiological functions and metabolic levels. Mitochondria-associated endoplasmic reticulum membranes serve as physical contact channels between the endoplasmic reticulum membrane and the mitochondrial outer membrane, formed by various proteins and protein complexes. …”
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5423
The Protective Effects of Annexin A1 in Acute Lung Injury Mediated by Nrf2
Published 2025-01-01“…Annexin A1 (AnxA1) is an important member of the annexin superfamily, known for its wide range of physiological functions. However, its potential protective effect against lipopolysaccharide (LPS)‐induced ALI remains unclear. …”
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5424
Identification of Heat-Responsive Genes in Guar [Cyamopsis tetragonoloba (L.) Taub]
Published 2020-01-01“…Taub] is a high-temperature tolerant plant with numerous works on its tolerance at morph-physiological levels but lack on molecular thermotolerance level. …”
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5425
Healthcare Practitioners’ perspectives on paediatric burns management at Korle Bu Teaching Hospital, Ghana
Published 2025-01-01“…Paediatric burns require specialized care due to the distinct anatomical and physiological characteristics of children, which make them more vulnerable to complications. …”
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5426
The Association between Short-Term PM2.5 Exposure and Long COVID on the Respiratory System
Published 2024-05-01“…The aforementioned symptoms impose significant effects on several physiological systems, especially the respiratory system. …”
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5427
Effects of Light Spectra on Nutritional Composition in Juvenile Sinonovacula constricta (Lamarck 1818) and Transcriptomic Analysis
Published 2024-01-01“…While previous research has highlighted the influence of light spectra on the growth, feeding rate, and various physiological characteristics of S. constricta, its impact on the biochemical composition of this species remains unclear. …”
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5428
Multiplanar Semicircular New-Generation Implant System Developed for Proximal Femur Periprosthetic Fractures: A Biomechanical Study
Published 2025-01-01“…It withstood higher physiological loads, offered better structural stability, and could be an alternative to existing fixation systems in clinical practice. …”
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5429
Profile of Transepidermal Water Loss (TEWL), Skin Hydration, and Skin Acidity (pH) in Indonesian Batik Workers
Published 2022-01-01“…Chemical substances used during batik processing may affect the physiological function of the batik worker’s skin barrier. …”
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5430
Heterologous Expression and Adaptive Evolution of ε-Poly-lysine Synthase Gene in <i>Corynebacterium glutamicum</i>
Published 2025-01-01“…In this experiment, a recombinant <i>C. glutamicum</i> capable of synthesizing ε-PL and exhibiting certain physiological resistance to ε-PL was obtained by amplifying <i>pls</i> and heterologous expression in <i>C. glutamicum</i> for the first time. …”
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5431
An in-vivo herb-drug interaction study of IME-9 and glimepiride in nicotinamide-STZ-induced diabetic rats
Published 2025-05-01“…It is worth noting that herbs comprise different amounts of active phytochemicals that can affect enzymatic systems, transporters and physiological processes. The focus of this study is to investigate the effects of the herbal formulation IME-9 on the pharmacokinetics (PK) and pharmacodynamics (PD) of Glimepiride (GP) and whether it is advantageous, detrimental or has no consequences. …”
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5432
Beef cattle performance and hair cortisol accumulation in silvopastoral and pastoral systems: a 2-year assessment
Published 2025-03-01“…A decrease of glucose levels in PA group was determined but further research is needed to clarify the effects of heat stress on physiological mechanisms that lead to a change in glucose levels. …”
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5433
VDR Polymorphisms in Autoimmune Connective Tissue Diseases: Focus on Italian Population
Published 2021-01-01“…Vitamin D is an important hormone involved in various physiologic processes, and its activity is linked to binding with vitamin D receptor (VDR). …”
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5434
Risk factors for cardio-cerebrovascular events among patients undergoing continuous ambulatory peritoneal dialysis and their association with serum magnesium
Published 2024-12-01“…Sociodemographic data, clinical physiological and biochemical indexes, and cardio-cerebrovascular event data were collected from 189 patients undergoing CAPD. …”
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5435
Changes in Hemodynamics and Tissue Oxygenation Saturation in the Brain and Skeletal Muscle Induced by Speech Therapy – A Near-Infrared Spectroscopy Study
Published 2011-01-01“…The changes in MWP were also significantly different between hexameter and alliteration, and hexameter and prose. Possible physiological explanations for these changes are discussed. …”
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5436
Characteristics of the gene pool of spring wheat (<i>Triticum aestivum</i> L.) for resistance to loose smut in the forest-steppe of Western Siberia
Published 2019-08-01“…The article presents the results of long-lasting studies of 350 genotypes of spring wheat of different ecological and geographical origin for resistance to disease. Physiological specialization of races was carried out on the basis of a differentiating set consisting of six varieties of soft wheat and three varieties of durum spring wheat. …”
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5437
Antioxidative Reactivity of L-Ascorbic Acid and D-Isoascorbic Acid Species towards Reduction of Hexachloroiridate (IV)
Published 2021-01-01“…The species versus pH and the species reactivity versus pH distribution diagrams were constructed endowing that the ascorbate/isoascorbate monoanionic form dominated the total reactivity at physiological pH. In addition, the value of pKa1 = 3.74 ± 0.05 for IAA at 25.0°C and 1.0 M ionic strength was determined in this work.…”
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5438
Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening
Published 2022-01-01“…However, none of the existing animal models could efficiently simulate the development of human organs and systems due to a lack of spatial information; the discrepancy in genetic, anatomic, and physiological basis between animals and humans limits detailed investigation. …”
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5439
High-Flow Nasal Cannula in Hypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis
Published 2020-01-01“…Likewise, no significant intergroup differences were found with regard to intensive care unit stay (SMD = −0.07, 95% CI: 0.26 to 0.11). Due to a physiological friendly interface and variation, HFNC showed a significant advantage over NIV in patients’ comfort and complication of therapy. …”
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5440
Development of Chitosan-Polyacrylic Acid Complex Systems for Enhanced Oral Delivery of Lactobacillus Gasseri and Bifidobacterium Bifidum Probiotics
Published 2025-01-01“…The probiotics exhibited high viability and maintain stability under physiological conditions, and showed a remarkable anti-biofilm activity. …”
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