Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) by Hiroaki Tanaka, Yasuhiro Tanaka, Yoichi Aoki, Masayuki Endo, Tomoaki Ikeda, Shintaro Maki, Masafumi Nii, Kayo Tanaka, Satoshi Tamaru, Toru Ogura, Yuki Nishimura, Tomomi Kotani, Akihiko Sekizawa, Masahiko Nakata, Koji Nakamura, Kenji Nagao, Ichiro Yasuhi, Hiroshi Kawamura, Sho Takakura, Mayumi Kotera, Takafumi Ushida, Norihiko Kikuchi, Tadatsugu Kinjo, Mayumi Takano, Sachie Suga, Michi Kasai, Osamu Yasui, Yuka Maegawa, Shigeru Aoki, Yoshio Yoshida

“…To establish further evidence for the efficacy of tadalafil in this setting, we planned a multicentre, randomised, placebo-controlled, double-blind trial.Methods and analysis This trial will be conducted in 180 fetuses with fetal growth restriction enrolled from medical centres in Japan; their mothers will be randomised into three groups: arm A, receiving two times per day placebo; arm B, receiving one time per day 20 mg tadalafil and one time per day placebo and arm C, receiving 20 mg two times per day tadalafil. …”
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Cohort profile: the Western Cape Pregnancy Exposure Registry (WCPER) by Landon Myer, Amy L Slogrove, Ushma Mehta, Mary-Ann Davies, Max Kroon, Greg Petro, Alexa Heekes, Andrew Boulle, Karen Fieggen, Chantal Stewart, Ayesha Osman, Natasha Rhoda, Emma Kalk, Florence Phelanyane, Jonathan Euvrard, Stefan Gebhardt, Kim Anderson

“…This relationship limits the missing data in the PER, allows validation and avoids misclassification in the population-level data set.Findings to date Approximately 5000 and 3500 pregnant women enter the data set annually at the urban and rural sites, respectively. …”
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Phenology and production of blackberry trees in the southern Minas Gerais by Guilherme dos Santos Cruz, Adriano Bortolotti da Silva, Nágla Maria Sampaio de Matos, Paulo Roberto Corrêa Landgraf, Ana Patrícia Alves Leão

“…“Tupy” overtook “Brazos” in number of fruits per plant, yield and estimated productivity (p<0.05). …”
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Will the increase of medical equipment affect medical expenditure? Empirical evidence from a quasi-experiment in China by Qiwei Deng, Zhongliang Zhou, Chi Shen, Dan Cao, Dantong Zhao, Yaxin Zhao, Jianmin Gao

“…Results The increase in the number of large-scale medical equipment by 1 — regardless of the initial configuration — resulted in the increase of the average cost per outpatient visit and the average cost per inpatient visit by 10.6% (p < 0.05) and 8.0% (p < 0.05), respectively. …”
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Prevalence and Risk Factors Associated with Hepatitis B and Hepatitis C Infections among Patients Undergoing Hemodialysis: A Single-Centre Study in Somalia by Mohamed Osman Omar Jeele, Rukia Omar Barei Addow, Faduma Nur Adan, Liban Hassan Jimale

“…Age, sex, duration of hemodialysis, number of hemodialysis sessions per week, history of blood transfusion, HbsAg, and anti-HCV antibodies were examined. …”
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The effect between metabolic syndrome and life expectancy after cancer diagnosis: Catalan cohort study by Tomàs López-Jiménez, Oleguer Plana-Ripoll, Talita Duarte-Salles, Anna Palomar-Cros, Diana Puente

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Burden and mortality of breast cancer attributed to diabetes and smoking in women: a secondary analysis based on Global Burden of Disease 2019 in North Africa and the Middle East by Fatemeh Khosravi Shadmani, Ali Jafari-Khounigh, Leili Abedi Gheshlaghi, Leila Rezakhani, Mozafar Khazaei

“…In 1990, the age-standardised mortality rate was 12.3 (95% CI: 11.0 to 14.2) per 100 000 people, and by 2019, it had increased to 15.2 (95% CI: 13.3 to 17.3) per 100 000. …”
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Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme by Stephen J Walters, Daniel Hind, Richard M Jacques, Steven A Julious, Joanne Rothwell, Oscar Bortolami, Laura Flight, Inês Bonacho dos Anjos Henriques-Cadby, Christopher Knox, Ben Nadin, Michael Surtees

“…The median recruitment rate (participants per centre per month) was found to be 0.92 (IQR 0.43–2.79) and the median retention rate (proportion of participants with valid primary outcome data at follow-up) was estimated at 89% (IQR 79–97%).Conclusions There is considerable variation in the consent, recruitment and retention rates in publicly funded RCTs. …”
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Oral Hygiene Practices among Saudi Arabian Children and Its Relation to Their Dental Caries Status by M. F. A. Quadri, M. A. Shubayr, A. H. Hattan, S. A. Wafi, A. H. Jafer

“…Sociodemographic data and information on oral hygiene practices like use of toothbrush, dental floss, siwak, frequency of brushing along with number of snack between meals per day, and consumption of sugar per day was obtained. …”
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Production of Biogas and Bio-fertilizer from Abattoir Waste as Sustainable Management, Eastern Ethiopia, 2019 by Sina Temsgen Tolera, Fekade Ketema Alemu

“…When in turned into cost, about $55,645 per a year of price could estimate from biogas and bio-fertilizer. …”
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Impact of Enhanced recovery after surgery (ERAS) protocols in idiopathic scoliosis of children: A systematic review with meta-analysis and trial sequential analysis by Soumya Sarkar, Bharat Yalla, Bhavuk Garg, Puneet Khanna

“…The required information size estimated for a power of 95% based on the 30% reduction in the LOS, 50% relative risk reduction for complications, reduction of per patient hospital cost of USD 3500 as per 2023 valuation, and reduction of mean intraoperative blood loss of 100 mL were 8599, 904, 499, and 499 respectively, was achieved. …”
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Global birth prevalence of major congenital anomalies: a systematic review and meta-analysis by Xiaolong Xie, Jiao Pei, Li Zhang, Yang Wu

“…Birth prevalence of congenital diaphragmatic hernia had a great decrease from 4.19 per 10,000 births in the 1960s to 1.30 per 10,000 births in the 2020s. …”
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Impact of monthly air pollution and weather conditions on cardiorespiratory mortality in Portuguese Metropolitan Areas by Ediclê de Souza Fernandes Duarte, Paulo Sérgio Lucio, Lígia Henriques-Rodrigues, Maria João Costa

“…The results show that PMA had a higher average CARDIO rate (202.94 [Deaths per 100 000]) compared to LMA (169.70 [Deaths per 100 000]). …”
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Direct Application of Coffee Pulp Vermicompost Produced from Epigeic Earthworms and Its Residual Effect on Vegetative and Reproductive Growth of Hot Pepper (Capsicum annuum L.) by Yohannes Zergaw, Temesgen Kebede, Dargie Tsegay Berhe

“…Generally, the three-way interaction effect of a media type, the application effect, and the application rate interaction effect were highly significant (P < 0.05) for the number of leaves per plant, the number of fruits per plant, and yield per hectare. …”
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Cyclic Fatigue Resistance of Nickel–Titanium Rotary Instruments after Simulated Clinical Use by Hana R. Ubaed, Diyar Kh. Bakr

“…The instruments were subdivided into group A 20 instruments (10 per system) that remain unused, group B 20 instruments (10 per system) instrumented 20 root canals (each file prepared 1 canal for 2 minutes), group C 20 instruments (10 per system) instrumented 40 canals each for 2 minutes (each file prepared 2 canals), group D of 20 instruments (10 per system) prepared 60 canals each for 2 minutes (each file prepared 3 canals). …”
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Correlation between Testicular Morphometric Parameters and Sperm Reserves in Ghanaian West African Dwarf Rams by Joseph Atawalna, Daniel Cobbinah Junior Essel, Nicholas Nettey, Patrick Mensah Amponsah

“…The weight, length, width, and volume of the testis were 63 ± 11 gram, 6.7 ± 0.44 cm, and 4.6 ± 0.40 and 74 ± 19 cm3, respectively, while the same parameters (except weight) for the cauda epididymis were 3.2 ± 0.35 cm, 1.8 ± 0.16 cm, and 5.48 ± 1.5 cm3, respectively. The sperm reserves per testis (SR), sperm reserves per gram testis (SRG), daily sperm production per testis (DSP), and daily sperm production per gram testis (DSPG) were (11,740 ± 386, 250 ± 6, 2350 ± 7.7, and 50 ± 1.0) million sperm cells, respectively. …”
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Mitral Valve Transcatheter Edge-to-Edge Repair Volumes and Trends by Kris Kumar, Timothy F. Simpson, Harsh Golwala, Adnan K. Chhatriwalla, Scott M. Chadderdon, Robert L. Smith, Howard K. Song, Ryan R. Reeves, Paul Sorajja, Firas E. Zahr

“…The nationwide incidence increased from 6.2 per 100,000 patients in 2015 to 23.8 per 100,000 patients in 2019, a 283% increase over the study period (Ptrend < 0.001). …”
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Effects of different protein levels on growth performance and body composition of spotted scat, Scatophagus argus by Dieu Vo, Thanh Duc Nguyen, Hang Thi Thuy Tran, Hung Duc Pham, Huy Van Nguyen

“…PER was lower at 30% or 42% protein contents in the diets than that of 34% or 38% protein treatments (p &lt; 0.05, and no significant difference in PER was found between CP34 and CP38 (p &gt; 0.05). …”
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Optimization of construction costs and energy consumption during the operation period of residential buildings (Case study: common residential buildings in Tehran) by Meysam Zekavat, Mansoureh Tahabaz, Mohammad Reza Hafezi

“…Then, by simulating the building considered in Builder Design software, the amount of gas consumption is 145.53 kWh per square meter, electricity consumption is 81.25 kWh per square meter and a total of 226.79 kWh per meter. …”
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Expectation-Maximization Aided Modified Weighted Sequential Energy Detector for Distributed Cooperative Spectrum Sensing by Mohammed Rashid, Jeffrey A. Nanzer

“…Simulation results show that EM-mWSED outperforms other schemes and its performance improves by increasing the average number of neighbors per SU in the network, and by increasing the SNR or the number of samples per energy statistic.…”
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