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Insights into the nuclear-organelle DNA integration in Cicuta virosa (Apiaceae) provided by complete plastid and mitochondrial genomes
Published 2025-02-01“…Abstract Background Gene transfer between the organelles and the nucleus plays a central role in shaping plant genome evolution. …”
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Complete mitogenome characteristics and phylogenetic analysis of traditional Chinese medicinal plant Tinospora sagittata (Oliv.) Gagnep. from the Menispermaceae family
Published 2025-02-01Subjects: “…Organelle…”
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Connections Across Open Water: A Bi‐Organelle, Genomics‐Scale Assessment of Atlantic‐Wide Population Dynamics in a Pelagic, Endangered Apex Predator Shark (Isurus oxyrinchus)
Published 2025-01-01“…Genomic‐scale population assessments for this apex predator species have not been previously available to inform management planning; thus, we investigated the population genetics of mako sharks across the Atlantic using a bi‐organelle genomics approach. Complete mitochondrial genome (mitogenome) sequences and genome‐wide SNPs from sharks distributed across the Atlantic revealed contrasting patterns of population structure across marker types. …”
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Autophagy-lysosome pathway in insulin & glucagon homeostasis
Published 2025-02-01“…Lysosome, a highly dynamic organelle, is an important nutrient sensing center. …”
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Cell migration in dense microenvironments
Published 2023-09-01“…However, increasing evidence shows that the nucleus is an active organelle, constantly sensing the surrounding environment and translating extracellular mechanical inputs into intracellular signaling. …”
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Engineering artificial photosynthetic life-forms through endosymbiosis
Published 2022-04-01“…We anticipate that these genetically tractable endosymbiotic platforms can be used for evolutionary studies, particularly related to organelle evolution, and also for synthetic biology applications.…”
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Metal complexes in cells: from design of catalytic antioxidants to imaging metal ions and designing metal-based probes in X-ray fluorescence and IR-imaging, a multidisciplinary col...
Published 2024-03-01“…Strategies to develop peptide-based metal complexes through conjugation of a LMW complex with peptides aimed at targeting specific organelle will be presented. Peptides can also be used to coordinate the metal ion: a combinatorial approach, with an activity-based screening, or and a rationale design using three-stranded coil-coiled, will also be presented.The cellular activity of a molecule is strongly dependent on its sub-cellular location. …”
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Cellular electron tomography of the apical complex in the apicomplexan parasite Eimeria tenella shows a highly organised gateway for regulated secretion.
Published 2022-07-01“…The apical complex of apicomplexan parasites is essential for host cell invasion and intracellular survival and as the site of regulated exocytosis from specialised secretory organelles called rhoptries and micronemes. Despite its importance, there are few data on the three-dimensional organisation and quantification of these organelles within the apical complex or how they are trafficked to this specialised region of plasma membrane for exocytosis. …”
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Germ granule-mediated mRNA storage and translational control
Published 2025-12-01“…These membrane-less organelles form through the condensation of RNA and proteins, governed by multivalent biomolecular interactions. …”
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Utilizing FRET-based Biosensors to Measure Cellular Phosphate Levels in Mycorrhizal Roots of Brachypodium distachyon
Published 2025-01-01“…Leveraging a semi-automated ImageJ macro for sensitized FRET analysis, this method provides a precise and efficient way to determine relative intracellular Pi levels at the level of individual cells or organelles.…”
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Exploring the maternal inheritance transmitted by the oocyte to its progeny
Published 2024-06-01“…This is what can be defined as the maternal inheritance composed of chromosomes, organelles, lipids, metabolites, proteins and RNAs. …”
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Determination of Dissociation Constants for the Interaction of Myosin-5a with its Cargo Protein Using Microscale Thermophoresis (MST)
Published 2025-02-01“…Myosin-5a (Myo5a) is an actin-dependent molecular motor that recognizes a diverse range of cargo proteins through its tail domain, playing a crucial role in the transport and localization of various organelles within the cell. We have identified a new interaction between Myo5a and its cargo protein melanophilin (Mlph), i.e., the interaction between the middle tail domain of Myo5a (Myo5a-MTD) and the actin-binding domain of Mlph (Mlph-ABD), by GST pulldown assay. …”
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High-fat diet and neuroinflammation: The role of mitochondria
Published 2025-02-01“…In recent years, increasing evidence has supported that high-fat diet (HFD) can induce the chronic, low-grade neuroinflammation in the brain, which is closely associated with the impairment of cognitive function. As the key organelles responsible for energy metabolism in the cell, mitochondria are believed to involved in the pathogenesis of a variety of neurological disorders. …”
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Intercellular communication is crucial in the regulation of healthy aging via exosomes
Published 2025-02-01“…The hallmarks of aging encompass a variety of molecular categories (genomic, telomeric, and epigenetic), organelles (proteostasis, autophagy, and mitochondria), cellular components (including stem cells), systems (such as intercellular communication and chronic inflammation), and environmental factors (dysbiosis and nutrient sensing). …”
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Polarity-JaM: an image analysis toolbox for cell polarity, junction and morphology quantification
Published 2025-02-01“…Abstract Cell polarity involves the asymmetric distribution of cellular components such as signalling molecules and organelles within a cell, alterations in cell morphology and cell-cell contacts. …”
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Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
Published 2007-07-01“…Uropathogenic Escherichia coli (UPEC), the primary causative agent of urinary tract infections, typically express filamentous adhesive organelles called type 1 pili that mediate both bacterial attachment to and invasion of bladder urothelial cells. …”
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Wogonin effects on the efflux transporters BCRP and MRP2, explain its effectiveness in ulcerative colitis: Implications for metabolic and transport interactions
Published 2025-02-01“…Interestingly, proteomic sequencing of mitochondrial subcellular organelles revealed that wogonin exhibited anti-UC effects by inhibiting afamin (AFM), with these effects modulated by BCRP and MRP2. …”
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Enucleated bone marrow-derived mesenchymal stromal cells regulate immune microenvironment and promote testosterone production through efferocytosis
Published 2025-02-01“…Methods Bone marrow-derived mesenchymal stromal cells (BMSCs) were enucleated by Ficoll density gradient centrifugation. The organelles and cellular functions of enucleated BMSCs were analyzed by immunofluorescence staining and flow cytometry. …”
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