Tofersen and other antisense oligonucleotides in ALS by Albert Ludolph, Maximilian Wiesenfarth

“…The advent of antisense oligonucleotide (ASO) therapies in neurodegenerative disorders is associated with enormous hope. …”
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Functionalized oligonucleotides, synthetic catalysts as enzyme mimics by Chardet, Crystalle, Serres, Sandra, Payrastre, Corinne, Escudier, Jean-Marc, Gerland, Béatrice

Subjects: “…Functionalized oligonucleotides…”
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Antisense oligonucleotides for the arterial hypertension mechanisms study and therapy by L. O. Klimov, A. A. Seryapina, V. F. Zarytova, A. S. Levina, A. L. Markel

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Conjugates of Phthalocyanines With Oligonucleotides as Reagents for Sensitized or Catalytic DNA Modification

“…<p>Several conjugates of metallophthalocyanines with deoxyribooligonucleotides were synthesized to investigate sequence-specific modification of DNA by them. Oligonucleotide parts of these conjugates were responsible for the recognition of selected complementary sequences on the DNA target. …”
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Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens by Rajagopal Krishnan, Dennis H. Oh

“…Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. …”
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Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences by Jianfeng Sun, Martin Philpott, Danson Loi, Gabriela Hoffman, Jonathan Robson, Neelam Mehta, Eleanor Calcutt, Vicki Gamble, Tom Brown, Tom Brown, Udo Oppermann, Adam P. Cribbs

“…Abstract Single-cell transcriptomics, which utilises barcodes and unique molecular identifiers (UMIs) for polyA+ mRNA capture, is compromised by oligonucleotide synthesis errors. To address this, we modified the oligonucleotide capture design and integrated an interposed anchor between the barcode and the UMI. …”
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Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington’s disease by Kaili Ou, Qingqing Jia, Dandan Li, Shihua Li, Xiao-Jiang Li, Peng Yin

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Coupling Strategies for the Synthesis of Peptide-Oligonucleotide Conjugates for Patterned Synthetic Biomineralization by Joshua D. Carter, Thomas H. LaBean

“…This work describes preparation strategies for peptide-oligonucleotide conjugates that combine the self-assembling behavior of DNA oligonucleotides with the molecular recognition capabilities of peptides. …”
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Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

Subjects: “…MT: Oligonucleotides: Therapies and Applications…”
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Synthesis of Specifically Modified Oligonucleotides for Application in Structural and Functional Analysis of RNA by Nico Rublack, Hien Nguyen, Bettina Appel, Danilo Springstubbe, Denise Strohbach, Sabine Müller

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Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference by Olga Golounina, Ildar Minniakhmetov, Ramil Salakhov, Rita Khusainova, Ekaterina Zakharova, Igor Bychkov, Natalia Mokrysheva

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Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits by Qi Yu, Zhengcao Liu, Ahmed Bilal Waqar, Bo Ning, Xianghong Yang, Masashi Shiomi, Mark J. Graham, Rosanne M. Crooke, Enqi Liu, Sijun Dong, Jianglin Fan

“…In the current study, we examined the effects of the rabbit CRP antisense oligonucleotides (ASO) on the development of atherosclerosis in WHHL rabbits. …”
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Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders by Yasir Qasim Almajidi, Rana Kadum Muslim, Yaseen T. khalf

Subjects: “…Antisense Oligonucleotide…”
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Development and functional evaluation of a psoralen-conjugated nucleoside mimic for triplex-forming oligonucleotides by Yu Mikame, Haruki Toyama, Chikara Dohno, Takehiko Wada, Asako Yamayoshi

“…Abstract Psoralen-conjugated triplex-forming oligonucleotides (Ps-TFOs) have been employed for the photodynamic regulation of gene expression by the photo-cross-linking of psoralen with the target DNA. …”
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Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and Hemocompatibility by Martina Schleicher, Jan Hansmann, Bentsian Elkin, Petra J. Kluger, Simone Liebscher, Agnes J. T. Huber, Olaf Fritze, Christine Schille, Michaela Müller, Katja Schenke-Layland, Martina Seifert, Heike Walles, Hans-Peter Wendel, Ulrich A. Stock

“…The objective of this study was the creation of cell adhesive DNA-oligonucleotide coatings on vascular implant surfaces. …”
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Inkjet-based oligonucleotide synthesis reagents: Formulation optimization and comparison of acetonitrile and propylene carbonate applications by Yu Xiao, Yongjin Peng, Zhen Rong, Xiaoyang He, Fei Sun, Shengqi Wang

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Phosphate-modified CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells by A. A. Ostanin, O. Y. Leplina, E. A. Burakova, T. V. Tyrinova, A. A. Fokina, A. S. Proskurina, S. S. Bogachev, D. A. Stetsenko, E. R. Chernykh

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Binding of Dumbbell Oligonucleotides to MoMuLV Reverse Transcriptase: Inhibitory Properties of RNase H Activity by Ajay Kumar

“…Dumbbell oligonucleotides with loops of various chemistry were synthesized. …”
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Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform by Tommaso Tabaglio, Taniya Agarwal, Wei Yuan Cher, Jin Rong Ow, Ah Keng Chew, Priscila Yun Qian Sun, Raja Sekhar Reddy Gurrampati, Hongfang Lu, Praveena Naidu, Hong Kai Ng, Xavier Le Guezennec, Shi Yan Ng, Manikandan Lakshmanan, Ernesto Guccione, Keng Boon Wee

Subjects: “…MT: Oligonucleotides: Therapies and Applications…”
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FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models by Timothy Weeden, Tyler Picariello, Brendan Quinn, Sean Spring, Pei-Yi Shen, Qifeng Qiu, Benjamin F. Vieira, Lydia Schlaefke, Ryan J. Russo, Ya-An Chang, Jin Cui, Monica Yao, Aiyun Wen, Nelson Hsia, Tama Evron, Katy Ovington, Pei-Ni Tsai, Nicholas Yoder, Bo Lan, Reshmii Venkatesan, John Hall, Cody A. Desjardins, Mo Qatanani, Scott Hilderbrand, John Najim, Zhenzhi Tang, Matthew K. Tanner, Romesh Subramanian, Charles A. Thornton, Oxana Ibraghimov-Beskrovnaya, Stefano Zanotti

“…Abstract Background We developed the FORCETM platform to overcome limitations of oligonucleotide delivery to muscle and enable their applicability to neuromuscular disorders. …”
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