CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context by Jan Rekowski, Christina Guo, Olga Solovyeva, Munyaradzi Dimairo, Mahtab Rouhifard, Dhrusti Patel, Emily Alger, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Johann de Bono, Thomas R. Jeffry Evans, Elizabeth Garrett–Mayer, Robert M. Golub, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Israel Maia, Adrian Mander, Lynley V. Marshall, James Matcham, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Lesley Seymour, Yoshiya Tanaka, Moreno Ursino, Christopher J. Weir, Christina Yap

“…Funding: This work is a further extension of the CONSORT-DEFINE study, which was funded by the UK Medical Research Council (MRC)-National Institute for Health and Care Research (NIHR) Methodology Research Programme (MR/T044934/1). …”
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Melanoma: From Research to Treatment by Paolo A. Ascierto, John M. Kirkwood, Francesco M. Marincola, Giuseppe Palmieri

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Targeting Oxidative Stress in Diabetic Complications: New Insights by Hao Wu, Lu Cai, Judy B. de Haan, Robertina Giacconi

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Post-vaccination campaign evaluation of systemic and mucosal immunity of trivalent oral poliovirus vaccine in Karachi, Pakistan (2020–2021): a cross-sectional studyResearch in cont... by Ali Faisal Saleem, Visalakshi Jeyaseelan, Zaubina Kazi, Mahjabeen Zehra, Muhammad Masroor Alam, Grace Macklin, Rocio Lopez Cavestany, Sajid Muhammad, Najeeb Rehman, Ondrej Mach

“…Stool and serum testing was performed at the National Institute of Health, Pakistan. Sera samples were analysed using microneutralization assays to quantify polio antibodies for all three serotypes: type 1, 2, and 3. …”
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Reasons for Delay in Seeking Care for Tuberculosis, Republic of Armenia, 2006–2007 by Dana Schneider, Scott J. N. McNabb, Marina Safaryan, Vladimir Davidyants, Ludmila Niazyan, Sona Orbelyan

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Randomised controlled trial comparing intraoperative cell salvage and autotransfusion with standard care in the treatment of hip fractures: a protocol for the WHITE 9 study by Mike Murphy, Nicholas Parsons, James Mason, Juul Achten, Duncan Appelbe, Edward Dickenson, Damian Griffin, Katy Mironov, Matthew Wyse, Amrita Athwal, Xavier Luke Griffin, Heather O'Connor

“…Otherwise, all care will be in accordance with the National Institute for Health and Care Excellence guidance. A minimum of 1128 patients will be recruited to obtain 90% power to detect a 0.075-point difference in the primary endpoint: EuroQol-5D-5L HRQoL at 4 months post injury. …”
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The short-, medium-, and long-term prevalence of physical health comorbidities in first-episode psychosis: a systematic review and meta-analysis protocol [version 2; peer review: 3... by Michael Norton, Brian O'Donoghue, Mary Clarke, Karen O'Connor, Jennifer Murphy, Anna Zierotin

“…Methods Using the PRISMA and MOOSE guidelines, Medline, Embase, PsycINFO, and CINAHL+, as well as Clinical Trials gov.uk, OpenGrey, WHO International Clinical Trials Registry Platform, Current Controlled Trials, United States National Institute of Health Trials Registry, and the Irish Health Repository, will be searched from inception. …”
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How outcomes are measured after spontaneous intracerebral hemorrhage: A systematic scoping review. by Sara Massicotte, Ronda Lun, Vignan Yogendrakumar, Brian Dewar, Hee Sahng Chung, Ricarda Konder, Holly Yim, Alexandra Davis, Dean Fergusson, Michel Shamy, Dar Dowlatshahi

“…The most frequently used functional assessment tool was the modified Rankin Scale (mRS) (60%), followed by the National Institute of Health Stroke Severity Scale (22%) and Barthel Index (21%). …”
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Stroke Event Factors among Adult Patients Admitted to Stroke Unit of Jimma University Medical Center: Prospective Observational Study by Ginenus Fekadu, Hunduma Wakassa, Firew Tekle

“…Majority of patients (40.5%) showed severe neurological deficit on admission and the mean National Institute of health stroke scale (NIHSS) was 15.71 ± 7.52. …”
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Is CT pulmonary angiography overutilized in the evaluation of patients with suspected pulmonary embolism? A retrospective study by Rabbani Mahmoud Daoud, Ahmed Majeed Mohamed, Muath Salahuddin Almajthoob, Salim Fredericks, Israa ElSayed Daoud, Moath Mahmoud Daoud, Mahmood AlSaeed

“…While the prevalence of PE has decreased in recent years, the overuse of computed tomography pulmonary angiography (CTPA) remains a concern. The National Institute for Health and Care Excellence (NICE) provides guidelines using the Wells score for PE assessment. …”
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Comparison of glycosylated fibronectin versus soluble fms-like tyrosine kinase/placental growth factor ratio testing for the assessment of pre-eclampsia: protocol for a multicentre... by Marcus Green, Chao Wang, Sarah Fisher, Amarnath Bhide, Ramesh Ganapathy, Basky Thilaganathan, Nouran Elbarbary

“…The prediction of pre-eclampsia in high-risk populations using angiogenic markers, such as serum placental growth factor (PlGF) assessment, has been shown to improve maternal outcomes and is recommended by the National Institute for Health and Care Excellence (NICE). However, such tests are not yet available at the point of care (POC). …”
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Tracking Persistent Symptoms in Scotland (TraPSS): a longitudinal prospective cohort study of COVID-19 recovery after mild acute infection by Jane Ormerod, Nicholas F Sculthorpe, Marie McLaughlin, Luke Cerexhe, Eilidh Macdonald, Antonio Dello Iacono, Nilihan E M Sanal-Hayes, Joanne Ingram, Rachel Meach, David Carless, Lawrence D Hayes

“…To understand the complexity of Long-COVID, the importance of symptom surveillance and prospective longitudinal studies is evident.Methods A 9-month longitudinal prospective cohort study was conducted within Scotland (n=287), using a mobile app to determine the proportion of recovered individuals and those with persistent symptoms and common symptoms, and associations with gender and age.Results 3.1% of participants experienced symptoms at month 9, meeting the criteria for Long-COVID, as defined by the National Institute for Health and Care Excellence terminology. …”
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Hyponatremia In Ischemic Stroke Patients And Its Relationship To Clinical Outcomes In Such Patients by Maria Zafar, Aneza Jalil, Amber Ghaffer, Mahnoor Yousaf, Sadia Batool

“…Stroke severity was measured through the National Institute of Health stroke scale score and serum sodium was measured at the time of admission in all patients to diagnose hyponatremia. …”
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Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort studyResearch in context by Safoora Gharibzadeh, Ash Routen, Cameron Razieh, Francesco Zaccardi, Claire Lawson, Clare Gillies, Simon Heller, Melanie Davies, Helen Atkins, Stephen C. Bain, Nazir L. Lone, Krisnah Poinasamy, Tunde Peto, Elizabeth Robertson, Bob Young, Desmond Johnston, Jennifer Quint, Jonathan Valabhji, Khalida Ismail, Michael Marks, Alex Horsley, Annemarie Docherty, Ewen Harrison, James Chalmers, Ling-Pei Ho, Betty Raman, Chris Brightling, Omer Elneima, Rachel Evans, Neil Greening, Victoria C. Harris, Linzy Houchen-Wolloff, Marco Sereno, Aarti Shikotra, Amisha Singapuri, Louise Wain, Claudia Langenberg, John Dennis, John Petrie, Naveed Sattar, Olivia Leavy, Mattew Richardson, Ruth M. Saunders, Anne McArdle, Hamish McASuley, Tom Yates, Kamlesh Khunti, C.E. Brightling, R.A. Evans, L.V. Wain, J.D. Chalmers, V.C. Harris, L.P. Ho, A. Horsley, M. Marks, K. Poinasamy, B. Raman, A. Shikotra, A. Singapuri, C.E. Brightling, R.A. Evans, L.V. Wain, R. Dowling, C. Edwardson, O. Elneima, S. Finney, N.J. Greening, B. Hargadon, V.C. Harris, L. Houchen--Wolloff, O.C. Leavy, H.J.C. McAuley, C. Overton, T. Plekhanova, R.M. Saunders, M. Sereno, A. Singapuri, A. Shikotra, C. Taylor, S. Terry, C. Tong, B. Zhao, D. Lomas, E. Sapey, C. Berry, C.E. Bolton, N. Brunskill, E.R. Chilvers, R. Djukanovic, Y. Ellis, D. Forton, N. French, J. George, N.A. Hanley, N. Hart, L. McGarvey, N. Maskell, H. McShane, M. Parkes, D. Peckham, P. Pfeffer, A. Sayer, A. Sheikh, A.A.R. Thompson, N. Williams, C.E. Brightling, W. Greenhalf, M.G. Semple, M. Ashworth, H.E. Hardwick, L. Lavelle-Langham, W. Reynolds, M. Sereno, R.M. Saunders, A. Singapuri, V. Shaw, A. Shikotra, B. Venson, L.V. Wain, A.B. Docherty, E.M. Harrison, A. Sheikh, J.K. Baillie, C.E. Brightling, L. Daines, R. Free, R.A. Evans, S. Kerr, O.C. Leavy, N.I. Lone, D. Lozano-Rojas, H.J.C. McAuley, K. Ntotsis, R. Pius, J. Quint, M. Richardson, M. Sereno, M. Thorpe, L.V. Wain, M. Halling-Brown, F. Gleeson, J. Jacob, S. Neubauer, B. Raman, S. Siddiqui, J.M. Wild, S. Aslani, G. Baxter, M. Beggs, C. Bloomfield, M.P. Cassar, A. Chiribiri, E. Cox, D.J. Cuthbertson, M. Halling-Brown, V.M. Ferreira, L. Finnigan, S. Francis, P. Jezzard, G.J. Kemp, H. Lamlum, E. Lukaschuk, C. Manisty, G.P. McCann, C. McCracken, K. McGlynn, R. Menke, C.A. Miller, A.J. Moss, T.E. Nichols, C. Nikolaidou, C. O'Brien, G. Ogbole, B. Rangelov, D.P. O'Regan, A. Pakzad, S. Piechnik, S. Plein, I. Propescu, A.A. Samat, L. Saunders, Z.B. Sanders, R. Steeds, T. Treibel, E.M. Tunnicliffe, M. Webster, J. Willoughby, J. Weir McCall, C. Xie, M. Xu, L.V. Wain, J.K. Baillie, H. Baxendale, C.E. Brightling, M. Brown, J.D. Chalmers, R.A. Evans, B. Gooptu, W. Greenhalf, H.E. Hardwick, R.G. Jenkins, D. Jones, I. Koychev, C. Langenberg, A. Lawrie, P.L. Molyneaux, A. Shikotra, J. Pearl, M. Ralser, N. Sattar, R.M. Saunders, J.T. Scott, T. Shaw, D. Thomas, D. Wilkinson, L.G. Heaney, A. De Soyza, D. Adeloye, C.E. Brightling, J.S. Brown, J. Busby, J.D. Chalmers, C. Echevarria, L. Daines, O. Elneima, R.A. Evans, J. Hurst, P. Novotny, C. Nicolaou, P. Pfeffer, K. Poinasamy, J. Quint, I. Rudan, E. Sapey, M. Shankar-Hari, A. Sheikh, S. Siddiqui, S. Walker, B. Zheng, J.R. Geddes, M. Hotopf, K. Abel, R. Ahmed, L. Allan, C. Armour, D. Baguley, D. Baldwin, C. Ballard, K. Bhui, G. Breen, K. Breeze, M. Broome, T. Brugha, E. Bullmore, D. Burn, F. Callard, J. Cavanagh, T. Chalder, D. Clark, A. David, B. Deakin, H. Dobson, B. Elliott, J. Evans, R.A. Evans, R. Francis, E. Guthrie, P. Harrison, M. Henderson, A. Hosseini, N. Huneke, M. Husain, T. Jackson, I. Jones, T. Kabir, P. Kitterick, A. Korszun, I. Koychev, J. Kwan, A. Lingford-Hughes, P. Mansoori, H. McAllister-Williams, K. McIvor, B. Michael, L. Milligan, R. Morriss, E. Mukaetova-Ladinska, K. Munro, A. Nevado-Holgado, T. Nicholson, C. Nicolaou, S. Paddick, C. Pariante, J. Pimm, K. Saunders, M. Sharpe, G. Simons, J.P. Taylor, R. Upthegrove, S. Wessely, G.P. McCann, S. Amoils, C. Antoniades, A. Banerjee, A. Bularga, C. Berry, P. Chowienczyk, J.P. Greenwood, A.D. Hughes, K. Khunti, C. Lawson, N.L. Mills, A.J. Moss, S. Neubauer, B. Raman, A.N. Sattar, C.L. Sudlow, M. Toshner, P.J.M. Openshaw, D. Altmann, J.K. Baillie, R. Batterham, H. Baxendale, N. Bishop, C.E. Brightling, P.C. Calder, C.M. Efstathiou, R.A. Evans, J.L. Heeney, T. Hussell, P. Klenerman, F. Liew, J.M. Lord, P. Moss, S.L. Rowland-Jones, W. Schwaeble, M.G. Semple, R.S. Thwaites, L. Turtle, L.V. Wain, S. Walmsley, D. Wraith, M.J. Rowland, A. Rostron, J.K. Baillie, B. Connolly, A.B. Docherty, N.I. Lone, D.F. McAuley, D. Parekh, A. Rostron, J. Simpson, C. Summers, R.G. Jenkins, J. Porter, R.J. Allen, R. Aul, J.K. Baillie, S. Barratt, P. Beirne, J. Blaikley, R.C. Chambers, N. Chaudhuri, C. Coleman, E. Denneny, L. Fabbri, P.M. George, M. Gibbons, F. Gleeson, B. Gooptu, B. Guillen Guio, I. Hall, N.A. Hanley, L.P. Ho, E. Hufton, J. Jacob, I. Jarrold, G. Jenkins, S. Johnson, M.G. Jones, S. Jones, F. Khan, P. Mehta, J. Mitchell, P.L. Molyneaux, J.E. Pearl, K. Piper Hanley, K. Poinasamy, J. Quint, D. Parekh, P. Rivera-Ortega, L.C. Saunders, M.G. Semple, J. Simpson, D. Smith, M. Spears, L.G. Spencer, S. Stanel, I. Stewart, A.A.R. Thompson, D. Thickett, R. Thwaites, L.V. Wain, S. Walker, S. Walsh, J.M. Wild, D.G. Wootton, L. Wright, S. Heller, M.J. Davies, H. Atkins, S. Bain, J. Dennis, K. Ismail, D. Johnston, P. Kar, K. Khunti, C. Langenberg, P. McArdle, A. McGovern, T. Peto, J. Petrie, E. Robertson, N. Sattar, K. Shah, J. Valabhji, B. Young, L.S. Howard, Mark Toshner, C. Berry, P. Chowienczyk, A. Lawrie, O.C. Leavy, J. Mitchell, J. Newman, L. Price, J. Quint, A. Reddy, J. Rossdale, N. Sattar, C. Sudlow, A.A.R. Thompson, J.M. Wild, M. Wilkins, S.J. Singh, W.D.-C. Man, J.M. Lord, N.J. Greening, T. Chalder, J.T. Scott, N. Armstrong, E. Baldry, M. Baldwin, N. Basu, M. Beadsworth, L. Bishop, C.E. Bolton, A. Briggs, M. Buch, G. Carson, J. Cavanagh, H. Chinoy, C. Dawson, E. Daynes, S. Defres, R.A. Evans, L. Gardiner, P. Greenhaff, S. Greenwood, M. Harvie, L. HOuchen-Wolloff, M. Husain, S. MacDonald, A. McArdle, H.J.C. McAuley, A. McMahon, M. McNarry, G. Mills, C. Nolan, K. O'Donnell, D. Parekh, Pimm, J. Sargent, L. Sigfrid, M. Steiner, D. Stensel, A.L. Tan, I. Vogiatzis, J. Whitney, D. Wilkinson, D. Wilson, M. Witham, D.G. Wootton, T. Yates, D. Thomas, N. Brunskill, S. Francis, S. Greenwood, C. Laing, K. Bramham, P. Chowdhury, A. Frankel, L. Lightstone, S. McAdoo, K. McCafferty, M. Ostermann, N. Selby, C. Sharpe, M. Willicombe, L. Houchen-Wolloff, J. Bunker, R. Gill, C. Hastie, R. Nathu, N. Rogers, N. Smith, A. Shaw, L. Armstrong, B. Hairsine, H. Henson, C. Kurasz, L. Shenton, S. Fairbairn, A. Dell, N. Hawkings, J. Haworth, M. Hoare, A. Lucey, V. Lewis, G. Mallison, H. Nassa, C. Pennington, A. Price, C. Price, A. Storrie, G. Willis, S. Young, P. Pfeffer, K. Chong-James, C. David, W.Y. James, C. Manisty, A. Martineau, O. Zongo, A. Sanderson, L.G. Heaney, C. Armour, V. Brown, T. Craig, S. Drain, B. King, N. Magee, D. McAulay, E. Major, L. McGarvey, J. McGinness, R. Stone, A. Haggar, A. Bolger, F. Davies, J. Lewis, A. Lloyd, R. Manley, E. McIvor, D. Menzies, K. Roberts, W. Saxon, D. Southern, C. Subbe, V. Whitehead, H. El-Taweel, J. Dawson, L. Robinson, D. Saralaya, L. Brear, K. Regan, K. Storton, J. Fuld, A. Bermperi, I. Cruz, K. Dempsey, A. Elmer, H. Jones, S. Jose, S. Marciniak, M. Parkes, C. Ribeiro, J. Taylor, M. Toshner, L. Watson, J. Weir McCall, J. Worsley, R. Sabit, L. Broad, A. Buttress, T. Evans, M. Haynes, L. Jones, L. Knibbs, A. McQueen, C. Oliver, K. Paradowski, J. Williams, E. Harris, C. Sampson, C. Lynch, E. Davies, C. Evenden, A. Hancock, K. Hancock, M. Rees, L. Roche, N. Stroud, T. Thomas-Woods, M. Babores, J. Bradley-Potts, M. Holland, N. Keenan, S. Shashaa, H. Wassall, E. Beranova, H. Weston, T. Cosier, L. Austin, J. Deery, T. Hazelton, C. Price, H. Ramos, R. Solly, S. Turney, L. Pearce, W. McCormick, S. Pugmire, W. Stoker, A. Wilson, N. Hart, L.A. Aguilar Jimenez, G. Arbane, S. Betts, K. Bisnauthsing, A. Dewar, P. Chowdhury, A. Chiribiri, A. Dewar, G. Kaltsakas, H. Kerslake, M.M. Magtoto, P. Marino, L.M. Martinez, C. O'Brien, M. Ostermann, J. Rossdale, T.S. Solano, E. Wynn, N. Williams, W. Storrar, M. Alvarez Corral, A. Arias, E. Bevan, D. Griffin, J. Martin, J. Owen, S. Payne, A. Prabhu, A. Reed, C. Wrey Brown, C. Lawson, T. Burdett, J. Featherstone, A. Layton, C. Mills, L. Stephenson, N. Easom, P. Atkin, K. Brindle, M.G. Crooks, K. Drury, R. Flockton, L. Holdsworth, A. Richards, D.L. Sykes, S. Thackray-Nocera, C. Wright, K.E. Lewis, A. Mohamed, G. Ross, S. Coetzee, K. Davies, R. Hughes, R. Loosley, L. O'Brien, Z. Omar, H. McGuinness, E. Perkins, J. Phipps, A. Taylor, H. Tench, R. Wolf-Roberts, L.S. Howard, O. Kon, D.C. Thomas, S. Anifowose, L. Burden, E. Calvelo, B. Card, C. Carr, E.R. Chilvers, D. Copeland, P. Cullinan, P. Daly, C.M. Efstathiou, L. Evison, T. Fayzan, H. Gordon, S. Haq, R.G. Jenkins, C. King, F. Liew, K. March, M. Mariveles, L. McLeavey, N. Mohamed, S. Moriera, U. Munawar, J. Nunag, U. Nwanguma, L. Orriss-Dib, D.P. O'Regan, A. Ross, M. Roy, E. Russell, K. Samuel, J. Schronce, N. Simpson, L. Tarusan, C. Wood, N. Yasmin, R. Reddy, A.-M. Guerdette, M. Hewitt, K. Warwick, S. White, A.M. Shah, C.J. Jolley, O. Adeyemi, R. Adrego, H. Assefa-Kebede, J. Breeze, M. Brown, S. Byrne, T. Chalder, A. Chiribiri, P. Dulawan, N. Hart, A. Hayday, A. Hoare, A. Knighton, M. Malim, C. O'Brien, S. Patale, I. Peralta, N. Powell, A. Ramos, K. Shevket, F. Speranza, A. Te, P. Beirne, A. Ashworth, J. Clarke, C. Coupland, M. Dalton, E. Wade, C. Favager, J. Greenwood, J. Glossop, L. Hall, T. Hardy, A. Humphries, J. Murira, D. Peckham, S. Plein, J. Rangeley, G. Saalmink, A.L. Tan, B. Whittam, N. Window, J. Woods, G. Coakley, D.G. Wootton, L. Turtle, L. Allerton, M. Beadsworth, A. Berridge, J. Brown, S. Cooper, A. Cross, D.J. Cuthbertson, S. Defres, S.L. Dobson, J. Earley, N. French, W. Greenhalf, H.E. Hardwick, K. Hainey, J. Hawkes, V. Highett, S. Kaprowska, G.J. Kemp, A.L. Key, S. Koprowska, L. Lavelle-Langham, N. Lewis-Burke, G. Madzamba, F. Malein, S. Marsh, C. Mears, L. Melling, M.J. Noonan, L. Poll, J. Pratt, E. Richardson, A. Rowe, M.G. Semple, V. Shaw, K.A. Tripp, B. Vinson, L.O. Wajero, S.A. Williams-Howard, J. Wyles, S.N. Diwanji, P. Papineni, S. Gurram, S. Quaid, G.F. Tiongson, E. Watson, B. Al-Sheklly, A. Horsley, C. Avram, P. Barran, J. Blaikely, M. Buch, N. Choudhury, D. Faluyi, T. Felton, T. Gorsuch, N.A. Hanley, T. Hussell, Z. Kausar, C.A. Miller, N. Odell, R. Osbourne, K. Piper Hanley, K. Radhakrishnan, S. Stockdale, D. Trivedi, A. De Soyza, C. Echevarria, A. Ayoub, J. Brown, G. Burns, G. Davies, H. Fisher, C. Francis, A. Greenhalgh, P. Hogarth, J. Hughes, K. Jiwa, G. Jones, G. MacGowan, D. Price, A. Sayer, J. Simpson, H. Tedd, S. Thomas, S. West, M. Witham, S. Wright, A. Young, M.J. McMahon, P. Neill, D. Anderson, H. Bayes, C. Berry, D. Grieve, I.B. McInnes, N. Basu, A. Brown, A. Dougherty, K. Fallon, L. Gilmour, K. Mangion, A. Morrow, K. Scott, R. Sykes, R. Touyz, E.K. Sage, F. Barrett, A. Donaldson, M. Patel, D. Bell, A. Brown, M. Brown, R. Hamil, K. Leitch, L. Macliver, J. Quigley, A. Smith, B. Welsh, G. Choudhury, J.K. Baillie, S. Clohisey, A. Deans, A.B. Docherty, J. Furniss, E.M. Harrison, S. Kelly, N.I. Lone, D.E. Newby, A. Sheikh, J.D. Chalmers, D. Connell, A. Elliott, C. Deas, J. George, S. Mohammed, J. Rowland, A.R. Solstice, D. Sutherland, C.J. Tee, N. Maskell, D. Arnold, S. Barrett, H. Adamali, A. Dipper, S. Dunn, A. Morley, L. Morrison, L. Stadon, S. Waterson, H. Welch, B. Jayaraman, T. Light, C.E. Bolton, P. Almeida, J. Bonnington, M. Chrystal, E. Cox, C. Dupont, S. Francis, P. Greenhaff, A. Gupta, L. Howard, W. Jang, S. Linford, L. Matthews, R. Needham, A. Nikolaidis, S. Prosper, K. Shaw, A.K. Thomas, L.P. Ho, N.M. Rahman, M. Ainsworth, A. Alamoudi, M. Beggs, A. Bates, A. Bloss, A. Burns, P. Carter, M. Cassar, K.M. Channon, J. Chen, F. Conneh, T. Dong, R.I. Evans, E. Fraser, X. Fu, J.R. Geddes, F. Gleeson, P. Harrison, M. Havinden-Williams, P. Jezzard, N. Kanellakis, I. Koychev, P. Kurupati, X. Li, E. Lukaschuk, K. McGlynn, H. McShane, C. Megson, K. Motohashi, S. Neubauer, D. Nicoll, G. Ogg, E. Pacpaco, M. Pavlides, Y. Peng, N. Petousi, J. Propescu, N. Rahman, B. Raman, M.J. Rowland, K. Saunders, M. Sharpe, N. Talbot, E. Tunnicliffe, W.D.-C. Man, B. Patel, R.E. Barker, D. Cristiano, N. Dormand, M. Gummadi, S. Kon, K. Liyanage, C.M. Nolan, S. Patel, O. Polgar, P. Shah, S.J. Singh, J.A. Walsh, J. Hurst, H. Jarvis, S. Mandal, S. Ahmad, S. Brill, L. Lim, D. Matila, O. Olaosebikan, C. Singh, M. Toshner, H. Baxendale, L. Garner, C. Johnson, J. Mackie, A. Michael, J. Pack, K. Paques, H. Parfrey, J. Parmar, N. Diar Bakerly, P. Dark, D. Evans, E. Hardy, A. Harvey, D. Holgate, S. Knight, N. Mairs, N. Majeed, L. McMorrow, J. Oxton, J. Pendlebury, C. Summersgill, R. Ugwuoke, S. Whittaker, W. Matimba-Mupaya, S. Strong-Sheldrake, S.L. Rowland-Jones, A.A.R. Thompson, J. Bagshaw, M. Begum, K. Birchall, R. Butcher, H. Carborn, F. Chan, K. Chapman, Y. Cheng, L. Chetham, C. Clark, Z. Coburn, J. Cole, M. Dixon, A. Fairman, J. Finnigan, L. Finnigan, H. Foot, D. Foote, A. Ford, R. Gregory, K. Harrington, L. Haslam, L. Hesselden, J. Hockridge, A. Holbourn, B. Holroyd-Hind, L. Holt, A. Howell, E. Hurditch, F. Ilyas, C. Jarman, A. Lawrie, E. Lee, J.-H. Lee, R. Lenagh, A. Lye, I. Macharia, M. Marshall, A. Mbuyisa, J. McNeill, S. Megson, J. Meiring, L. Milner, S. Misra, H. Newell, T. Newman, C. Norman, L. Nwafor, D. Pattenadk, M. Plowright, J. Porter, P. Ravencroft, C. Roddis, J. Rodger, P. Saunders, J. Sidebottom, J. Smith, L. Smith, N. Steele, G. Stephens, R. Stimpson, B. Thamu, N. Tinker, K. Turner, H. Turton, P. Wade, S. Walker, J. Watson, J.M. Wild, I. Wilson, A. Zawia, R. Aul, M. Ali, A. Dunleavy, D. Forton, N. Msimanga, M. Mencias, T. Samakomva, S. Siddique, J. Teixeira, V. Tavoukjian, J. Hutchinson, L. Allsop, K. Bennett, P. Buckley, M. Flynn, M. Gill, C. Goodwin, M. Greatorex, H. Gregory, C. Heeley, L. Holloway, M. Holmes, J. Kirk, W. Lovegrove, T.A. Sewell, S. Shelton, D. Sissons, K. Slack, S. Smith, D. Sowter, S. Turner, V. Whitworth, I. Wynter, L. Warburton, S. Painter, J. Tomlinson, C. Vickers, T. Wainwright, D. Redwood, J. Tilley, S. Palmer, G.A. Davies, L. Connor, A. Cook, T. Rees, F. Thaivalappil, C. Thomas, A. Butt, M. Coulding, H. Jones, S. Kilroy, J. McCormick, J. McIntosh, H. Savill, V. Turner, J. Vere, E. Fraile, J. Ugoji, S.S. Kon, H. Lota, G. Landers, M. Nasseri, S. Portukhay, A. Hormis, A. Daniels, J. Ingham, L. Zeidan, M. Chablani, L. Osborne, M. Marks, J.S. Brown, N. Ahwireng, B. Bang, D. Basire, R.C. Chambers, A. Checkley, R. Evans, M. Heightman, T. Hillman, J. Hurst, J. Jacob, S. Janes, R. Jastrub, M. 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Walker, M. Halling-Brown, G. Breen, M. Hotopf, K. Lewis, N. Williams

“…Funding: UK Research and Innovation and National Institute for Health Research. The study was approved by the Leeds West Research Ethics Committee (20/YH/0225) and is registered on the ISRCTN Registry (ISRCTN10980107).…”
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Stem Cell–Based Therapies via Different Administration Route for Stroke: A Meta-analysis of Comparative Studies by Gabriella Jeanne Mulia, Novelia Anna, John Chung-Che Wu, Hon-Ping Ma, Yung-Hsiao Chiang, Ju-Chi Ou, Kai-Yun Chen

“…Primary outcomes included the National Institute of Health Stroke Scale (NIHSS), Barthel Index (BI), and modified Rankin Scale (mRS), while secondary outcomes included mortality and adverse events. …”
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Cost–consequence analysis of COPD treatment according to NICE and GOLD recommendations compared with current clinical practice in the UK by Jennifer K Quint, Helene Vioix, Toby Capstick, Sue Langham, Jennifer Cook, Antony Wright, Shamika de Silva

“…Objectives The objective of this study was to model the clinical and economic impact of adapting current clinical practice in the management of patients with chronic obstructive pulmonary disease (COPD) to treatment according to national and international guideline recommendations.Design Treatment mapping was undertaken to hypothetically redistribute patients from current clinical practice, representing actual prescribing patterns in the UK, to an alternative recommendation-based treatment scenario, representing prescribing in accordance with either National Institute for Health and Care Excellence (NICE) guidance [NG115] or Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 strategy.Setting Primary care practices in the UK (1-year time horizon).Participants Adults with COPD undergoing long-acting inhaler maintenance therapy in the UK (N=1 067,531).Interventions Inhaler maintenance therapy.Outcome measures Costs and clinical outcomes (type of treatment, rates of moderate and/or severe exacerbations, and mild-to-moderate and/or severe pneumonia events) were modelled for the two alternative pathways.Results Compared with current clinical practice, treating patients according to NICE guidance resulted in an estimated annual reduction in expenditure of £46.9 million, and an estimated annual reduction in expenditure of over £43.7 million when patients were treated according to GOLD 2020 strategy. …”
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Seroprevalence of Borrelia burgdorferi sensu lato antibodies in English adult blood donors: A nationwide cross-sectional study, 2021–2022 by Eilish Hart, John Tulloch, Daniel Bailey, Tim Brooks, Heli Harvala, Peter Simmonds, Roberto Vivancos, Neil French, Amanda Semper

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Understanding how, for whom and under what circumstances telecare can support independence in community-dwelling older adults: a realist review by Lauren Fothergill, Niall Hayes, Yvonne Latham, Jenny Hamilton, Saiqa Ahmed, Carol Holland

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GENOTYPIC DIVERSITY OF DENGUE VIRUS IN AEDES MOSQUITOES COLLECTED FROM DENGUE HOTSPOT AREAS IN KUALA LUMPUR AND SELANGOR, MALAYSIA by Wan Najdah Wan Mohamad Ali, Zurainee Mohamed Nor, Rafidah Ali, Rohani Ahmad, Yvonne Ai-Lian Lim

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DNA Barcoding of Fish, Insects, and Shellfish in Korea by Dae-Won Kim, Won Gi Yoo, Hyun Chul Park, Hye Sook Yoo, Dong Won Kang, Seon Deok Jin, Hong Ki Min, Woon Kee Paek, Jeongheui Lim

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