Combination therapy versus monotherapy: retrospective analysis of antibiotic treatment of enterococcal endocarditis by Razan Saman, Christopher P. Primus, Robert West, Simon J. Woldman, Jonathan A. T. Sandoe

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A core set of risk factors in individuals at risk of rheumatoid arthritis: a systematic literature review informing the EULAR points to consider for conducting clinical trials and... by Daniel Aletaha, Kulveer Mankia, Paul Emery, Deshire Alpizar-Rodriguez, Andreas Kerschbaumer, Andrea Di Matteo, Heidi Siddle, Joel Kerry

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Tale of two zones: investigating the clinical outcomes and research gaps in peripheral and transition zone prostate cancer through a systematic review and meta-analysis by Pedro Oliveira, Robert G Bristow, Ananya Choudhury, Ashwin Sachdeva, Noel Clarke, Hitesh Mistry, Amin Ali, Thiraviyam Elumalai, BhanuPrasad Venkatesulu, Lauren Hekman, Esther Baena

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Williams Syndrome with a “Twist” by Despoina Maritsi, Lydia Kossiva, George Vartzelis

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Acute Torsion of Appendicular Mucocele by Farshid Ejtehadi, James Brooks, Hebah Hassan Ali, Vardhini Vijay

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Osteochondral lesions of talus by Jitendra Mangwani, Claire Brockett, Elise Pegg

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Qualitative methods: the missing link in orthopaedic research by Samantha Jones, Sarah Tyson

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Are Aortic Stent Grafts Safe in Pregnancy? by Nader Khandanpour, Tapan A. Mehta, M. Adiseshiah, Felicity J. Meyer

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PD-1-expressing macrophages and CD8 T cells are independent predictors of clinical benefit from PD-1 inhibition in advanced mesothelioma by Solange Peters, Urania Dafni, Panagiota Zygoura, Sanjay Popat, Mary O'Brien, Rolf A Stahel, Alessandra Curioni-Fontecedro, Georges Coukos, Amy Roy, Riyaz Shah, Krisztian Homicsko, James Spicer, Stephen P Finn, David Gilligan, Maxim Norkin, Stephanie Tissot, Nicholas Shakarishvili, Anthony Pope, Patricia Fisher, Sylvie Rusakiewicz, Ekaterina Fortis, Nesa Marti, Roswitha Kammler

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How do staff work in NHS hospital operations management meetings to support resilience in everyday service delivery? A qualitative study by L. Sutton, C. Tarrant, J. Willars, T. Coats, M. Simmonds, D. Mclean, A. Boyle, K. Dreesbeimdiek, S. Richter, A. Oyedijo, D. Roland

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A woman’s place is in theatre: women’s perceptions and experiences of working in surgery from the Association of Surgeons of Great Britain and Ireland women in surgery working grou... by Maria Irene Bellini, Yitka Graham, Catherine Hayes, Roxanna Zakeri, Rowan Parks, Vassilios Papalois

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Feasibility of implementing a rapid-learning methodology to inform radiotherapy treatments: key professional stakeholders’ views by Corinne Faivre-Finn, Kevin Franks, Fiona McDonald, David P French, Daniel Johnson, Arbaz Kapadi, Gareth Price, Rebecca Holley, Kate Wicks, Kathryn Banfill, Gareth Webster

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First-Line Chemo-Immunotherapy in SCLC: Outcomes of a Binational Real-World Study by Laura Moliner, MD, Núria Zellweger, MSc, Sabine Schmid, MD, Martina Bertschinger, MD, Christine Waibel, MD, Ferdinando Cerciello, MD, PhD, Patrizia Froesch, MD, Michael Mark, MD, Adrienne Bettini, MD, Pirmin Häuptle, MD, Veronika Blum, MD, Lisa Holer, MSc, Stefanie Hayoz, PhD, Martin Früh, MD, Samreen Ahmed, FRCP, MD, MBBS, MSc, Shradha Bhagani, MD, Nicola Steele, MD, Hannah-Leigh Gray, BSc, Stephen D. Robinson, MD, Michael Davidson, MD (Res), Samantha Cox, MD, MSc, MBBCh, Taha Khalid, MD, Tom R. Geldart, MD, Luke Nolan, FRCS, PhD, Deborah C. Scott, MBChB (MRCP), Lindsay Hennah, MD, Tom Newsom-Davis, MD, PhD, Emma Rathbone, MD, PhD, Catherine Handforth, MD, Arshi Denton, MD, Shairoz Merchant, PhD, Fiona Blackhall, MD, PhD, Laetitia A. Mauti, MD, Raffaele Califano, MD, Sacha I. Rothschild, MD, PhD

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Continuous Assessment of Labour Pain using Handgrip Force by Nadine Wickboldt, Georges Savoldelli, Benno Rehberg-Klug

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Obstructive Jaundice due to Pancreatic Involvement as an Initial Presentation of Adult Acute Lymphoblastic Leukemia by Oreoluwa Oladiran, Ifeanyi Nwosu

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Reply to: “Understanding virologic heterogeneity in chronic hepatitis B treatment” by Philippa C. Matthews, Tingyan Wang, Eleanor Barnes

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Treatment Dilemmas in a Young Man Presenting with Narcolepsy and Psychotic Symptoms by Victoria Fernandez, Sharon Davies, Nicola Walters

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Utility of 5-ALA for resection of CNS tumours other than high-grade gliomas: a protocol for a systematic review by Michael D Jenkinson, Ashwin Venkatesh, Colin Watts, Michael T C Poon, Victoria Wykes, Stephen John Price, Puneet Plaha, Georgios Solomou, Melissa Gough, Conor S Gillespie, Aref-Ali Gharooni, Waqqas Patel

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Challenges of early renal cancer detection: symptom patterns and incidental diagnosis rate in a multicentre prospective UK cohort of patients presenting with suspected renal cancer by Michelle Wilson, Naveen S Vasudev, Grant D Stewart, Adebanji Adeyoju, Jon Cartledge, Michael Kimuli, Shibendra Datta, Damian Hanbury, David Hrouda, Grenville Oades, Poulam Patel, Naeem Soomro, Mark Sullivan, Jeff Webster, Peter J Selby, Rosamonde E Banks

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Developing a core outcome set for interventions in people with mild cognitive impairment: study protocol by Angus G K McNair, Nicholas Turner, Alan Richardson, Elizabeth Coulthard, Jemima Dooley, Julie Clayton, Sam Harding, Sarah Rudd, Victoria Grace Gabb, Winsome Barrett-Muir, Natalie Woodward, Sophie Alderman, Joseph Webb

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