Protocol for a first-in-human feasibility study of T regulatory cells (TR004) for inflammatory bowel disease using (ex vivo) Treg expansion (TRIBUTE) by Jennifer Clough, Peter Irving, A Toby Prevost, Graham M Lord, Joana Vasconcelos, James B Canavan, Beverley Rodger, D Macallan

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Impact of introducing transnasal endoscopy on expanding diagnostic endoscopy services by Nigel Trudgill, Hasan Haboubi, Jeff Turner, Laura Munglani, Tom Crosby, Ben Thomas Crosby, Karen Wright, Kay Charles, Wendy Evans, Megan Mathias, Stevie Davies, Badr Abdalla

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Allogenic Cultured Limbal Epithelial Transplantation and Cultivated Oral Mucosal Epithelial Transplantation in Limbal Stem Cells Deficiency: A Comparative Study by Mohamed Elalfy, Kareem Elsawah, Sundas Maqsood, Nigel Jordan, Mansour Hassan, Ahmed Zaki, Zisis Gatzioufas, Samer Hamada, Damian Lake

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Comparison of glycosylated fibronectin versus soluble fms-like tyrosine kinase/placental growth factor ratio testing for the assessment of pre-eclampsia: protocol for a multicentre... by Marcus Green, Chao Wang, Sarah Fisher, Amarnath Bhide, Ramesh Ganapathy, Basky Thilaganathan, Nouran Elbarbary

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Light exposure profiles differ between myopes and non-myopes outside school hours by John G Lawrenson, Rakhee Shah, Rohit Dhakal, Byki Huntjens, Pavan Kumar Verkicharla

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Association between polypharmacy and falls in older adults: a longitudinal study from England by Nafeesa N Dhalwani, Melanie J Davies, Kamlesh Khunti, Harini Sathanapally, Radia Fahami, Sam Seidu

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Delphi consensus survey: the opinions of patients living with refractory ulcerative proctitis and the health care professionals who care for them by Philip Smith, Stuart Bloom, Christian Selinger, Ailsa Hart, Christopher Lamb, Anjan Dhar, Helen Steed, Matthew Brookes, Jonathan Macdonald, Ian Arnott, Shellie Radford, Gordon W Moran, Susan Ritchie, Victoria Fletcher, Jonathan Segal, N Sharma, Shahida Din, Daniel Gaya, J Butterworth, S Andrews, P Adams, Deborah Morris, Pearl Avery, Philip Oppong, Mario Guslandi, Maro Kyriacou, Rachel Linger, Madhoor Ramdeen, John Appleton, John Anneh, B Kussel

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Differential attainment at national selection for higher surgical training: a retrospective cohort study by Amanda Lee, Jennifer Cleland, John Hines, Peter Brennan, Ricky Ellis, Yasin Al-Tawarah

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Occult hepatitis B virus infection: risk for a blood supply, but how about individuals’ health? by Michael X. Fu, Ahmed Elsharkawy, Brendan Healy, Celia Jackson, Daniel Bradshaw, Emma Watkins, Ines Ushiro-Lumb, Jaisi Griffiths, James Neuberger, Kathryn Maguire, Monica Desai, Neil McDougall, Nicole Priddee, Stephen T. Barclay, Stuart Blackmore, Peter Simmonds, William L. Irving, Heli Harvala

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Negative symptoms in schizophrenia: a study in a large clinical sample of patients using a novel automated method by Robert Stewart, Hitesh Shetty, Matthew Broadbent, Angus Roberts, Rashmi Patel, Philip McGuire, Richard D Hayes, Nishamali Jayatilleke, Genevieve Gorrell, Chin-Kuo Chang, Richard Jackson, Nadia Foskett, Caroline Johnston

“…Objectives To identify negative symptoms in the clinical records of a large sample of patients with schizophrenia using natural language processing and assess their relationship with clinical outcomes.Design Observational study using an anonymised electronic health record case register.Setting South London and Maudsley NHS Trust (SLaM), a large provider of inpatient and community mental healthcare in the UK.Participants 7678 patients with schizophrenia receiving care during 2011.Main outcome measures Hospital admission, readmission and duration of admission.Results 10 different negative symptoms were ascertained with precision statistics above 0.80. 41% of patients had 2 or more negative symptoms. …”
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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... by Amy Robinson, Kamaljit Khalsa, Arjun Chandna, John Bowen, Viva Levee, Jan Coebergh, Tom Solomon, Clive Graham, David Turner, Robert Tilley, Tim Jones, Susan Hopkins, Matthew Stevens, Daniel White, Celestine Eshiwe, Anna Goodman, Ramandeep Singh, Robert S Heyderman, Nicholas Davies, Joseph Thompson, Ed Moran, Martin Williams, Rhea O’Regan, Simon Tiberi, Jonathan Lambourne, Naomi Bulteel, Susan Larkin, Ruth McEwen, Hassan Paraiso, Aarti Shah, Martin Wiselka, Sylviane Defres, Ernest Mutengesa, Maria Krutikov, Ruth Owen, David Griffith, David Harvey, Trupti Patel, Brendan Davies, Emma Mclean, Joanna Allen, Ali Khan, Alastair Miller, Ashutosh Deshpande, Christopher Green, Lewis Jones, Mark Melzer, Fiona McGill, Amanda Fife, Nimal Wickramasinghe, Stephanie Harris, Ewan Hunter, Jayne Ellis, Benedict Rogers, Imogen Fordham, Elen Vink, Victoria Ward, Anna Smith, Andrew Rosser, Alison Muir, Ken Woodhouse, John Shone, Iain Crossingham, Ryan Jayesinghe, Eavan Muldoon, Avneet Shahi, Terry John Evans, Jeremy Wong, Eloisa MacLachlan, Amy Chue, Karishma Gokani, Katherine Ajdukiewicz, Lucinda Barrett, Frances Edwards, Adam Usher, Mairi McLeod, Su su Htwe, Grace Duane, Nicholas Wong, Jennifer Poyner, Jenni Crane, Ollie Lloyd, Emma Chisholm, Ildiko Kustos, Sam Sutton, M. Estee Torok, Isobel Ramsay, Monica Ivan, Joshua York, Jennifer Ansett, Maithili Varadarajan, Priya Sekhon, James Cruise, Shivani Kanabar, Mirella Ling, Charlotte Milne, Jayanta Sarma, Aline Wilson, Lynn Urquhart, Sahar Eldirdiri, Leila White, Jody Aberdein, Phillip Simpson, Hnin Hay Mar, Keying Tan, Eint Shwe Zin thein, Mahmoud Aziz, Anthony Cadwgan, Natasha Weston, Salman Zeb, Angela Houston, Louise Wootton, Iona Willingham, Aimee Johnson, Ashley Horsley, Eamonn Trainor, Olivier Gaillemin, Nicholas J Norton, Katie Cheung, Megan Duxbury, Emilie Bellhouse, Helena Brezovjakova, Kanitkar Tanmay, Alexsander Dawidziuk, Razan Saman, Hugh Adler, Elshadai Ejere, Yiwen Soo, Wendy Beadles, Heather Sturgeon, Brodie Cameron, David Chadwick Ben Tomlinson, Claire McGoldrick, Katie McDowell, Mpho Molosiwa, Katherine FlackAdrian Kennedy, Phoebe Cross, Fay Perry, Vithusha Inpadhas, Sarathy Selvam, Vhairi Bateman, Henry Wu, Monika Pasztor, Ajanthiha Karunakaran, Basma Soliman, Andrew Blanshard, Harish Reddy, Helen Chesterfield, Ben Schroeder, Tee Keat Teoh, Sathyavani Subbarao, Caryn RosmarinLucy Bell, Emma McGuire, Robert Serafino, Ishaan Bhide, Karanjeet Sagoo, Indran Balakrishnan, Kajal Patel, Barzo Faris, Graeme Calver, Ricky Singh, Hazel Sanghvi, Mohamed Eltayeb, Rathur Haris

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Metabolomics Biomarkers in Prediction of Sudden Infant Death Syndrome: The Role of Short Chain Fatty Acids by Maria Aslam, Omer Riaz, Jawaria Aslam, Dost Muhammad Khan, Mustafa Hameed, Muhammad Suleman, Rizwan Shahid, Turke Althobaiti, Naeem Ramzan

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Performance of HPV E4 and p16INK4a biomarkers in predicting regression of cervical intraepithelial neoplasia grade 2 (CIN2): protocol for a historical cohort study by David Jenkins, Mark H Stoler, Anne Hammer, Torben Steiniche, Lone Kjeld Petersen, Patti E Gravitt, Rikke Kamp Damgaard, Maurits NC de Koning, Wim GV Quint, John Doorbar, Johnny Kahlert

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Complex high-risk indicated PCI (CHIP-PCI): is it safe to let fellows-in-training perform it as primary operators? by Tim Kinnaird, Zia Ul-Haq, Holly Morgan, Anirban Choudhury, Majd B Protty, Alexander Chase, David Hildick-Smith, Shantu Bundhoo, Saad Hasan, Diluka Premawardhana, Ahmed Hailan, Mohammed Shugaa Addin, Hussain Hussain

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Surgical Treatment Intensity at the End of Life in Patients With Cancer: A Systematic Review by Samuel Lawday, BMBS, MByRes, Benjamin E. Zucker, MA, MBBS, MRCS, Shona Gardner, MBChB, MRCS, James Robb, MBChB, MA, Lorna Leandro, MA, BM, BCh, William Hollingworth, PhD, Jane Blazeby, MBChB, MD, Angus G.K. McNair, PhD, FRCS, Charlotte Chamberlain, PhD, MRCP

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Exploratory study of patients’ and carers’ preferences for postdischarge surgical wound monitoring using survey and interviews by Keith Wilson, Nigel Westwood, Catherine Wloch, Pauline Harrington, Luke J Rogers, Judith Tanner, Gavin Murphy, Colin S Brown, Jeremy Dearling, Ricky Vaja, Melissa Rochon, Lyn Brierley Jones

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Meta-analysis to evaluate the comparative effectiveness of enzalutamide and abiraterone acetate for first-line treatment of metastatic castration-resistant prostate cancer in real-... by Armen Aprikian, Amit Bahl, Aurelius Omlin, Giulia Baciarello, Abhiroop Chakravarty, Prashanth Kondaparthi, Georgia Gourgioti, Thomas McLean, Alexis Serikoff, Andrew Chilelli

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Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

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Randomised controlled trial comparing intraoperative cell salvage and autotransfusion with standard care in the treatment of hip fractures: a protocol for the WHITE 9 study by Mike Murphy, Nicholas Parsons, James Mason, Juul Achten, Duncan Appelbe, Edward Dickenson, Damian Griffin, Katy Mironov, Matthew Wyse, Amrita Athwal, Xavier Luke Griffin, Heather O'Connor

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Evaluation of two electronic-rehabilitation programmes for persistent knee pain: protocol for a randomised feasibility trial by Philip G Conaghan, Kim L Bennell, Mark Conner, Rana S Hinman, Sarah R Kingsbury, Elizabeth M A Hensor, Gretl A McHugh, Christine Comer, Dawn Groves-Williams, Rachel K Nelligan

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