The Role of NADPH Oxidase 2 in Leukocytes by Jennifer W. Leiding, Clayton E. Mathews, Danielle E. Arnold, Jing Chen

Subjects: “…NADPH oxidase…”
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Regulation of cardiovascular diseases by histone deacetylases and NADPH oxidases by Hui Yan, Yidan Yin, Yichen Zhou, Zhanghang Li, Yuxing Li, Lingxuan Ren, Jiazheng Wen, Weirong Wang

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Measuring the rate of NADPH consumption by glutathione reductase in the cytosol and mitochondria. by Kenneth K Y Ting, Eric Floro, Riley Dow, Jenny Jongstra-Bilen, Myron I Cybulsky, Jonathan V Rocheleau

“…<h4>Background</h4>NADPH is an essential co-factor supporting the function of enzymes that participate in both inflammatory and anti-inflammatory pathways in myeloid cells, particularly macrophages. …”
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NADPH oxidase 4 expression in the normal endometrium and in endometrial cancer by Christine Degasper, Andrea Brunner, Natalie Sampson, Irina Tsibulak, Verena Wieser, Hannah Welponer, Christian Marth, Heidi Fiegl, Alain Gustave Zeimet

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Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase. by Balázs Rada, Meghan A Jendrysik, Lan Pang, Craig P Hayes, Dae-Goon Yoo, Jonathan J Park, Samuel M Moskowitz, Harry L Malech, Thomas L Leto

“…Pyocyanin-induced NETs also require the NADPH oxidase because NET release in chronic granulomatous disease neutrophils was greatly reduced. …”
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Transhydrogenase promotes the robustness and evolvability of E. coli deficient in NADPH production. by Hsin-Hung Chou, Christopher J Marx, Uwe Sauer

“…To address this question we studied laboratory evolution of pathway-engineered Escherichia coli that underproduces the redox cofactor NADPH on glucose. Literature suggests multiple possibilities to restore NADPH homeostasis. …”
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Interplay between energy metabolism and NADPH oxidase-mediated pathophysiology in cardiovascular diseases by Haipeng Jie, Jingjing Zhang, Shuzhen Wu, Luyao Yu, Shengnan Li, Bo Dong, Feng Yan

Subjects: “…NADPH oxidases…”
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NADPH Oxidase 4: Crucial for Endothelial Function under Hypoxia—Complementing Prostacyclin by Heike Brendel, Jennifer Mittag, Anja Hofmann, Helene Hempel, Sindy Giebe, Patrick Diaba-Nuhoho, Steffen Wolk, Christian Reeps, Henning Morawietz, Coy Brunssen

Subjects: “…NADPH oxidase 4…”
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Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives by Zilv Ye, Zilv Ye, Sutong Wang, Zhengdong Wan, Birun Huang, Jiawei Guo, Jiawei Guo

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Thioredoxin reductase from Bacillus cereus exhibits distinct reduction and NADPH‐binding properties by Marita Shoor, Ingvild Gudim, Hans‐Petter Hersleth, Marta Hammerstad

“…Low‐molecular‐weight (low Mr) thioredoxin reductases (TrxRs) are homodimeric NADPH‐dependent dithiol flavoenzymes that reduce thioredoxins (Trxs) or Trx‐like proteins involved in the activation networks of enzymes, such as the bacterial class Ib ribonucleotide reductase (RNR). …”
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Correction: Endothelial AIP1 regulates vascular remodeling by suppressing NADPH Oxidase-2 by Jiqin Zhang, Jiqin Zhang, Chaofei Chen, Chaofei Chen, Li Li, Huanjiao J. Zhou, Fenghe Li, Haifeng Zhang, Luyang Yu, Yuxin Chen, Wang Min, Wang Min

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Investigation of effect of NADPH inhibitors on ischemic reperfusion injury based on the NOD2 signaling pathway by ZHANG Xiao-lin, LIU Wen-li, LI Guang-yuan, MA Fang, XIA Tian-yu, LI Di, ZHANG Zhe, TAN Zhi-cheng

“…Objective To investigate effect and its mechanism of NADPH inhibitors on ischemia/reperfusion injury(IRI)based on the nucleotide-binding oligomerization domain-2(NOD2) signaling pathway. …”
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Residual NADPH Oxidase Activity and Isolated Lung Involvement in X-Linked Chronic Granulomatous Disease by Maria J. Gutierrez, George D. McSherry, Faoud T. Ishmael, Alexandra A. Horwitz, Gustavo Nino

“…Chronic granulomatous disease (CGD) is characterized by inherited immune defects resulting from mutations in the NADPH oxidase complex genes. The X-linked type of CGD is caused by defects in the CYBB gene that encodes gp91-phox, a fundamental component of the NADPH oxidase complex. …”
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Enhancing NADPH to restore redox homeostasis and lysosomal function in G6PD-deficient microglia by Abir Mondal, Soumyadeep Mukherjee, Prince Upadhyay, Isha Saxena, Soumya Pati, Shailja Singh

“…Our study shows that G6PD deficiency in microglia reduces NADPH levels, disrupting redox balance and lysosomal function. …”
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Overstretch causes lipid accumulation in vascular smooth muscle cells dependent on NADPH oxidase 1 by Jiazhen Zhang, Qinfen Li, Suoqi Ding, Wei Xu, Jilei Su, Jingang Cui, Yongsheng Ding

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Expression of genes belonging to the interacting TLR cascades, NADPH-oxidase and mitochondrial oxidative phosphorylation in septic patients. by Laura A Nucci, Sidnéia S Santos, Milena K C Brunialti, Narendra Kumar Sharma, Flavia R Machado, Murillo Assunção, Luciano C P de Azevedo, Reinaldo Salomao

“…<h4>Conclusion</h4>Our data show changes in the expression of genes belonging to the interacting TLR cascades, NADPH-oxidase and oxidative phosphorylation. Importantly, distinct patterns are clearly observed in surviving and non-surviving patients. …”
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A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes by Marie Scherschel, Jan-Ole Niemeier, Lianne J. H. C. Jacobs, Markus D. A. Hoffmann, Anika Diederich, Christopher Bell, Pascal Höhne, Sonja Raetz, Johanna B. Kroll, Janina Steinbeck, Sophie Lichtenauer, Jan Multhoff, Jannik Zimmermann, Tanmay Sadhanasatish, R. Alexander Rothemann, Carsten Grashoff, Joris Messens, Emmanuel Ampofo, Matthias W. Laschke, Jan Riemer, Leticia Prates Roma, Markus Schwarzländer, Bruce Morgan

“…Abstract The NADPH/NADP+ redox couple is central to metabolism and redox signalling. …”
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The Possibility of Destruction of Cellular NADPH in the Presence of Free Fe(II) Ion, Arsine, and Other Hazardous Species by Seyyed Amir Siadati, Mohammad Ali Ebrahimzadeh, Esmaeil Babazadeh

Subjects: “…nadph…”
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mRNA level of antioxidant genes and activity of NADPH-generating enzymes in rotenone-induced parkinsonism in rats by E. D. Kryl’skii, G. A. Razuvaev, T. N. Popova, L. E. Nikhaev, A. I. Akinina

“…The enzyme activity was studied spectrophotometrically by the formation of NADPH. Real-time PCR was used to analyze the level of gene mRNA.Results. …”
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Impact of Hospitalization on Sarcopenia, NADPH-Oxidase 2, Oxidative Stress, and Low-Grade Endotoxemia in Elderly Patients by Chiara Bagnato, Arianna Magna, Elena Mereu, Sciaila Bernardini, Simona Bartimoccia, Roberta Marti, Pietro Enea Lazzerini, Alessandra D’Amico, Evaristo Ettorre, Giovambattista Desideri, Pasquale Pignatelli, Francesco Violi, Roberto Carnevale, Lorenzo Loffredo, Neurodegenerative Study Group

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