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Awareness and attitudes of pregnant women concerning genetic disorders and pregnancy termination in northeastern Iran
Published 2025-01-01“…Additionally, the number of children was correlated with congenital blindness, Duchenne muscular dystrophy, autism, Proteus syndrome, Klinefelter syndrome, anencephaly, mental retardation (MR), quadriplegia, and severe learning disability and mental health (LDMH). …”
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Actinorhodopsin: an efficient and robust light-driven proton pump for bionanotechnological applications
Published 2025-02-01“…Abstract Actinorhodopsins are encoded by a distinct group of microbial rhodopsin (MR) genes predominant in non-marine actinobacteria. …”
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Successful living donor liver transplantation of the left lateral sector with simultaneous atypical resection of the S2 for focal nodular hyperplasia
Published 2022-05-01“…According to magnetic resonance imaging, there is a zone of increased MR signal, with contrast enhancement uniformly accumulating contrast in the arterial phase. …”
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Flexible and cost-effective deep learning for accelerated multi-parametric relaxometry using phase-cycled bSSFP
Published 2025-02-01“…Furthermore, DNNs utilizing the full information of the underlying complex-valued MR data demonstrated ability to accelerate the data acquisition by a factor of 3. …”
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Translating Runyankole- Rukiga Folktales Into English.
Published 2024“…Research findings showed that three folktales adopted from Mr. Karwemera's folktales were successfully translated from RR into English. …”
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66
A wicked problem: Systemic issues surrounding Canadian equestrian dressage and dressage horse welfare
Published 2025-01-01“…An ethnographic case study approach was employed, where MR spent 2–6 weeks with each of the four participating Equestrian Canada Certified dressage coaches and their riders (at least four riders per coach for a total of 19 riders). …”
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Construction and application of a stratified nursing intervention program for postoperative delirium after Stanford type A aortic dissection: a quasi-experimental trial
Published 2025-02-01“…Trial registration The National Health Security Information Platform’s Medical Research Registration Information System has registered this study under the registration number MR-33–22-022978.…”
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Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis
Published 2025-02-01“…Mendelian Randomization (MR) studies revealed that expression of HMGCR was associated with an increased risk of migraine with odds ratio (OR) ranging from 1.38 to 1.55 (P < 0.001). …”
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Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial...
Published 2022-10-01“…Key secondary outcomes are as follows: (1) total alcohol consumption, (2) phosphatidyl-ethanol, an objective biomarker for alcohol, (3) plasma psilocin, the active metabolite, to establish a possible therapeutic range, (4) the acute subjective drug experience as a possible predictor of treatment outcome and (5) neuronal response to alcohol cues and cognitive flexibility within corticostriatal pathways by use of functional MR brain imaging 1-week postdosing.Ethics and dissemination Ethical approval has been obtained from the Committee on Health Research Ethics of the Capital Region of Denmark (H-20043832). …”
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Case report: an unusual long-term evolution of a diffuse midline glioma, H3K27 altered
Published 2025-02-01“…Molecular neuropathology revealed the diagnosis of diffuse midline glioma with a H3K27M mutation WHO (World Health Organization) CNS (central nervous system) grade 4. Interestingly, MR imaging conducted for migraine diagnosis 6 years ago in retrospect already showed a small, nodular T2w hyperintense lesion in the right thalamus.ConclusionDespite a more precise, molecularly driven classification of pediatric HGG (high-grade glioma) in the 5th edition of the WHO classification of CNS tumors, many genetic factors influencing the biological tumor development as well as the precise molecular evolution of tumors remain unclear. …”
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Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization
Published 2025-02-01“…After rigorous screening and Mendelian randomization (MR) tests, genetically predicted overall BC (OR: 1.17, P = 0.0045) and ER(estrogen receptors) + BC (OR: 1.21, P = 0.0006) showed a potential causal association with intracranial meningioma. …”
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The causal relationship of cigarette smoking to metabolic disease risk and the possible mediating role of gut microbiota
Published 2025-01-01“…Our future studies should consider conducting other ethnic groups MR analyses, particularly with larger sample sizes. …”
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37例以孤立性头昏为表现的病毒性脑炎特点和误诊分析
Published 2025-01-01“…18.92%(7/37)患者脑电图慢波增多(AUC值:0.60)。13.51%(5/37)患者头MR表现为皮层肿胀(AUC值:0.60)。抗病毒治疗后患者的头昏等级下降(<italic>Z=</italic>-4.899<italic>,P<</italic>0.001),平滑跟踪异常(<italic>Z=</italic>-4.583<italic>,P<</italic>0.001)减少,CSF转化型淋巴细胞比例(<italic>t=</italic>4.281<italic>,P<</italic>0.001)、大淋巴细胞比例下降(<italic>t=</italic>6.905<italic>,P<</italic>0.001)。…”
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Contemporary Management of Patients With Chagas Cardiomyopathy in Bolivia
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Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context
Published 2025-03-01“…We also carried out additional validations including colocalization, linkage disequilibrium check and host–pathogen interactome predictions. We integrated MR findings with clinical trial evidence from several drug gene related databases to identify drugs with repurposing potential. …”
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Comparative Efficacy of NAFLD Therapies and Biomarker Associations: A Meta-Analysis Based on Liver Fat Content
Published 2025-01-01“…Background and Aims: This study aims to conduct a comprehensive quantitative analysis of various nonalcoholic fatty liver disease (NAFLD) therapeutics, utilizing magnetic resonance (MR)-detected liver fat content (LFC) as the efficacy endpoint, and to identify biomarkers correlated with changes in LFC based on published literature. …”
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Screening of COPD patients using the COPD diagnostic questionnaire and a portable spirometer in primary healthcare institutions: a cross-sectional, diagnostic study
Published 2025-02-01“…Trial Registration This study has been registered in national medical research registration and filing information system of China, www.medicalresearch.org.cn , Trail registration number: MR-11-23-020214.…”
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Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [13C]bicarbonate metabolism in mice
Published 2025-02-01“…In studies of the mouse brain using hyperpolarized [1-13C]pyruvate, there are few reports that the signal of [13C]bicarbonate, a product of oxidative phosphorylation metabolized from [1-13C]pyruvate, was detected using MR spectroscopic imaging (MRSI) that allows spatial mapping of metabolism, although there have been reports of [13C]bicarbonate signals being detected by pulse-acquire sequences in the entire brain. …”
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Unveiling prognostic value of JAK/STAT signaling pathway related genes in colorectal cancer: a study of Mendelian randomization analysis
Published 2025-02-01“…Prognostic genes were selected from JAK-STAT-DEGs through Mendelian randomization (MR), univariate Cox regression, and least absolute shrinkage and selection operator (LASSO) analyses. …”
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