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Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study
Published 2025-02-01“…We conducted the causal estimates using the inverse variance-weighted method (IVW), with sensitivity analyses using MR-Egger, weighted median, weighted mode, and MR pleiotropy residual sum and outlier (MR-PRESSO) analysis. …”
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42
Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes
Published 2025-02-01“…MR analysis revealed a significant positive correlation between serum uric acid levels and PAH (odds ratio (OR) 1.106, 95% confidence intervals (CI) 1.021-1.200, P = 0.014), corroborated by a replication MR analysis (OR 1.859, 95% CI 1.130–3.057, P = 0.015). …”
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43
Modifiable factors for irritable bowel syndrome: evidence from Mendelian randomisation approach
Published 2025-01-01“…Subsequently, multiresponse MR (MR2) was employed to further examine these associations. …”
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44
The causal effects between low back pain and cerebrospinal fluid metabolites: a two-sample Mendelian randomization study
Published 2025-02-01“…We applied several MR methods, including inverse variance weighting, weighted median, MR-Egger, Wald ratio, and MR-PRESSO, to test the causal relationship and conducted a sensitivity analysis to assess the robustness of the results. …”
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45
Mechanism of warmed malate ringer’s solution in fluid resuscitation in improving the lethal triad of severe trauma
Published 2025-02-01“… Objective To explore the role and mechanism of warm malate ringer’s solution (MR) in resuscitation of the lethal triad caused by severe trauma. …”
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Serum Matrix Metalloproteinases and Risk of Urologic Cancers: A Bidirectional Mendelian Randomization Study
Published 2025-02-01“…We performed inverse variance-weighted MR as the primary method for calculating the overall effects of multiple instruments, while implementing additional MR methods and sensitivity analyses. …”
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Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study
Published 2025-02-01“…This study aims to explore these relationships using Mendelian Randomization (MR) analysis.Methods: Data from 191 resting-state functional MRI (rsfMRI) phenotypes and endometriosis genetic datasets were analyzed using both forward and reverse MR approaches. …”
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48
Carbonyl-nitrogen multi-resonance emitters for efficient OLEDs with high color purity
Published 2025-02-01“…Abstract Multi-resonance (MR) materials hold an intriguing feature of narrow emission spectra and have attracted considerable attention in the manufacture of high-definition organic light-emitting diodes (OLEDs). …”
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49
Murcott (Honey Tangerine)
Published 2018-04-01“…Mr. Smith most likely obtained the original trees from the USDA. …”
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50
Murcott (Honey Tangerine)
Published 2018-04-01“…Mr. Smith most likely obtained the original trees from the USDA. …”
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51
Genetic evidence for the liver-brain axis: lipid metabolism and neurodegenerative disease risk
Published 2025-02-01“…The analysis included primary MR, sensitivity analyses, and multivariable MR, which considered potential mediators. …”
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52
Causal links between obesity, lipids, adipokines, and cognition: a bidirectional Mendelian-randomization analysis
Published 2025-02-01“…Bidirectional inverse-variance weighted Mendelian randomization (MR) was employed to evaluate the relationship between adiposity and cognitive function. …”
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53
Automatic Adaptive Algorithm for Delineation of Cerebral-Spinal Fluid Regions for Non-contrast Magnetic Resonance Imaging Volumetry and Cisternography in Mice
Published 2025-01-01“…Still, accurate delineation of the brain structures remains a crucial task of MR image evaluation. This study presents a novel analytical algorithm developed in MATLAB for the automatic segmentation of cerebrospinal fluid (CSF) spaces in preclinical non-contrast MR images of the mouse brain. …”
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54
Beyond the Comfort Zone: Strenuous Sports as a Preventive Tactic Against Benign Prostatic Hyperplasia
Published 2025-02-01“…In this study, Mendelian randomization (MR) was used to explore the potential causal relationship between strenuous sports and prostatic hypertrophy. …”
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The mediating role of thyroid-related hormones between thyroid dysfunction diseases and osteoporosis: a mediation mendelian randomization study
Published 2025-02-01“…We used two-sample Mendelian randomization (MR) analysis to elucidate the causal relationship between TDFDs and OP. …”
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Causal associations between dietary habits and liver cancer risk: a two-sample Mendelian randomization study
Published 2025-02-01“…Mendelian randomization (MR) is frequently employed to investigate the causal link between exposure and results. …”
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57
Genetic Associations Between Specific Sleep-Related Phenotypes and Idiopathic Sudden Sensorineural Hearing Loss: A Mendelian Randomization Analysis
Published 2025-02-01“…The heterogeneity was determined using MR Egger and IVW, and pleiotropy by MR Egger.Results: There were 39/27 single nucleotide polymorphisms (SNPs) related to insomnia, 68 SNPs related to sleep duration, 31 SNPs related to daytime dozing, 13 SNPs related to sleep disorders, and 20 SNPs related to sleep apnoea. …”
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Causal relationship between educational attainment and the occurrence of venous thromboembolism
Published 2025-02-01“…We aimed to assess the causal effect of EA on VTE using the two-sample mendelian randomization (MR) method. Methods Data mining was conducted on the genome wide association studies (GWAS), with exposure factor EA and outcome factor VTE. …”
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The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD
Published 2025-02-01“…Subsequently, sensitivity analyses were conducted, employing Cochran’s Q test to assess heterogeneity, MR-PRESSO and MR-Egger tests to assess pleiotropy, and reverse MR and Steiger directionality tests to rule out reverse causality. …”
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