Showing 61 - 80 results of 686 for search '"Molecular Medicine"', query time: 0.07s Refine Results
  1. 61
    Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome

    Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome by Rosalie Matico, Karolien Grauwen, Dhruv Chauhan, Xiaodi Yu, Irini Abdiaj, Suraj Adhikary, Ine Adriaensen, Garcia Molina Aranzazu, Jesus Alcázar, Michela Bassi, Ellen Brisse, Santiago Cañellas, Shubhra Chaudhuri, Francisca Delgado, Alejandro Diéguez-Vázquez, Marc Du Jardin, Victoria Eastham, Michael Finley, Tom Jacobs, Ken Keustermans, Robert Kuhn, Josep Llaveria, Jos Leenaerts, Maria Lourdes Linares, Maria Luz Martín, Rosa Martín-Pérez, Carlos Martínez, Robyn Miller, Frances M Muñoz, Michael E Muratore, Amber Nooyens, Laura Perez-Benito, Mathieu Perrier, Beth Pietrak, Jef Serré, Sujata Sharma, Marijke Somers, Javier Suarez, Gary Tresadern, Andres A Trabanco, Dries Van den Bulck, Michiel Van Gool, Filip Van Hauwermeiren, Teena Varghese, Juan Antonio Vega, Sameh A Youssef, Matthew J Edwards, Daniel Oehlrich, Nina Van Opdenbosch

    Published 2024-12-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  2. 62
    Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain

    Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain by Chae-Jeong Lee, Seung Hyun Jang, Jiwoo Lim, Hyunju Park, So-Hee Ahn, Seon Young Park, Hyangmi Seo, Soo-Jin Song, Jung-A Shin, Chulhee Choi, Heon Yung Gee, Youn-Hee Choi

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  3. 63
    mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction

    mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction by Seon-Yeong Lee, Jeonghyeon Moon, A Ram Lee, Young-Mee Moon, Jeong Won Choi, Chae Rim Lee, Su Been Jeon, Hee Su Sohn, Jeehee Youn, Dongyun Shin, Sung-Hwan Park, Mi-La Cho

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  4. 64
    BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling

    BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling by Chengzhu Zhao, Yoshiko Inada, Souta Motoike, Daisuke Kamiya, Kyosuke Hino, Makoto Ikeya

    Published 2024-12-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  5. 65
    SPOCK2 controls the proliferation and function of immature pancreatic β-cells through MMP2

    SPOCK2 controls the proliferation and function of immature pancreatic β-cells through MMP2 by Katarzyna Blaszczyk, Anna P. Jedrzejak, Natalia Ziojla, Ekaterina Shcheglova, Karolina Szarafin, Artur Jankowski, Christine A. Beamish, Jolanta Chmielowiec, Omaima M. Sabek, Ashok Balasubramanyam, Sanjeet Patel, Malgorzata Borowiak

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  6. 66
    RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining

    RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  7. 67
    Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair

    Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair by Shishi Tao, Yue Pu, Eun Ju Yang, Guowen Ren, Changxiang Shi, Li-Jie Chen, Liang Chen, Joong Sup Shim

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  8. 68
    Targeting to BMP9 to restrain flare-up of fibrodysplasia ossificans progressiva

    Targeting to BMP9 to restrain flare-up of fibrodysplasia ossificans progressiva by Qiwen Li, Quan Yuan

    Published 2024-12-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  9. 69
    Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease

    Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease by Lindsey Van Haute, Petra Páleníková, Jia Xin Tang, Pavel A Nash, Mariella T Simon, Angela Pyle, Monika Oláhová, Christopher A Powell, Pedro Rebelo-Guiomar, Alexander Stover, Michael Champion, Charulata Deshpande, Emma L Baple, Karen L Stals, Sian Ellard, Olivia Anselem, Clémence Molac, Giulia Petrilli, Laurence Loeuillet, Sarah Grotto, Tania Attie-Bitach, Jose E Abdenur, Robert W Taylor, Michal Minczuk

    Published 2024-11-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  10. 70
    The inflammasome adaptor protein ASC promotes amyloid deposition in cryopyrin-associated periodic syndromes

    The inflammasome adaptor protein ASC promotes amyloid deposition in cryopyrin-associated periodic syndromes by Cristina Alarcón-Vila, Laura Hurtado-Navarro, Sandra V Mateo, Alejandro Peñín-Franch, Carlos M Martínez, Cristina Molina-López, María C Baños, Ana I Gómez, Javier Gómez-Román, Alberto Baroja-Mazo, Juan I Arostegui, Natalia Palmou-Fontana, Juan J Martínez-García, Pablo Pelegrin

    Published 2024-12-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  11. 71
    MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2

    MT-100, a human Tie2-agonistic antibody, improves penile neurovasculature in diabetic mice via the novel target Srpx2 by Fang-Yuan Liu, Young-Lai Cho, Fitri Rahma Fridayana, Lashkari Niloofar, Minh Nhat Vo, Yan Huang, Anita Limanjaya, Mi-Hye Kwon, Jiyeon Ock, Seon-Jin Lee, Guo Nan Yin, Nam-Kyung Lee, Ji-Kan Ryu

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  12. 72
    Activators of the 26S proteasome when protein degradation increases

    Activators of the 26S proteasome when protein degradation increases by Donghoon Lee

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  13. 73
    Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB

    Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB by Yongzhan Sun, Quan Zou, Huizheng Yu, Xiaoping Yi, Xudan Dou, Yu Yang, Zhiheng Liu, Hong Yang, Junya Jia, Yupeng Chen, Shao-Kai Sun, Lirong Zhang

    Published 2024-11-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  14. 74
    NSCLC mechanobiology: Delving into the intricate pathways involved in the dynamic interplay between tumors and the TME

    NSCLC mechanobiology: Delving into the intricate pathways involved in the dynamic interplay between tumors and the TME by Kostas A. Papavassiliou, Antonios N. Gargalionis, Efthimia K. Basdra, Athanasios G. Papavassiliou

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  15. 75
    PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival

    PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival by Chenxiao Yu, Marco Tigano, Erin L Seifert

    Published 2024-11-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  16. 76
    AIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples

    AIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples by Hyeonseong Jeon, Junhak Ahn, Byunggook Na, Soona Hong, Lee Sael, Sun Kim, Sungroh Yoon, Daehyun Baek

    Published 2023-08-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  17. 77
    Editorial: Neuroinflammatory aspects in neurological disorders

    Editorial: Neuroinflammatory aspects in neurological disorders by Pinto Alipio, Loidl C. Fabián, Goldstein Jorge

    Published 2025-02-01
    “…Frontiers in Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  18. 78
    Author Correction: Disrupting TSLP–TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases

    Author Correction: Disrupting TSLP–TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseases by Partho Protim Adhikary, Temilolu Idowu, Zheng Tan, Christopher Hoang, Selina Shanta, Malti Dumbani, Leah Mappalakayil, Bhuwan Awasthi, Marcel Bermudez, January Weiner, Dieter Beule, Gerhard Wolber, Brent D G Page, Sarah Hedtrich

    Published 2024-11-01
    “…EMBO Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  19. 79
    Single-cell RNA sequencing and spatial transcriptomics of esophageal squamous cell carcinoma with lymph node metastases

    Single-cell RNA sequencing and spatial transcriptomics of esophageal squamous cell carcinoma with lymph node metastases by Wei Guo, Bolun Zhou, Lizhou Dou, Lei Guo, Yong Li, Jianjun Qin, Zhen Wang, Qilin Huai, Xuemin Xue, Yin Li, Jianming Ying, Qi Xue, Shugeng Gao, Jie He

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:
  20. 80
    Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation

    Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation by Jeeho Kim, Young Jin Jeon, In-Youb Chang, Jung-Hee Lee, Ho Jin You

    Published 2025-01-01
    “…Experimental and Molecular Medicine…”
    Get full text
    Article
    Save to List
    Saved in:

Search Tools: