Disparity of serum uric acid threshold for CKD among hypertensive and non-hypertensive individuals by Bowen Zhu, Fang Li, Weidong Zhang, Shuan Zhao, Nana Song, Shi Jin, Ziyan Shen, Yufei Lu, Yang Li, Hong Liu

“…In the propensity score matched (PSM) population, the result remained roughly constant.Conclusion Therefore, even moderate levels of sUA was associated with a higher risk of CKD in middle-aged hypertensive patients, who warrant stricter sUA control.…”
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Global burden of osteoarthritis from 1990 to 2019 attributable to high body mass index by Siming Yang, Licheng Zhou, Wanchen Gong, Bin Guo, Linfeng Wang

“…In particular, this burden was higher in women than in men; primarily affected middle-aged and older adults; and was generally greater in high-SDI regions than in low-SDI regions.…”
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Clinical Comparison between HD-tDCS and tDCS for Improving Upper Limb Motor Function: A Randomized, Double-Blinded, Sham-Controlled Trial by Yaqin Zeng, Ruidong Cheng, Li Zhang, Shan Fang, Shaomin Zhang, Minmin Wang, Qian Lv, Yunlan Dai, Xinyi Gong, Feng Liang

“…Stroke is a common and frequently occurring disease among middle-aged and elderly people, with approximately 55%−75% of patients remaining with upper limb dysfunction. …”
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Serum microRNAs as Diagnostic Markers in Polycystic Ovary Syndrome: A Narrative Review by K Lavanya, N Palaniappan, VM Vinodhini, Santhi Silambanan

“…Polycystic Ovarian Syndrome (PCOS) is thought to be common worldwide among middle-aged women. Increased androgen production, recurrent anovulatory cycles and ovaries with multiple cysts are symptoms of this multiorgan endocrine condition. …”
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The Accuracy of the Clinical Carpal Tunnel Syndrome Diagnosis before the Nerve Conduction Studies by A. Atkočiūnas, A. Šimkutė, Rasa Mameniškienė

“…According to different studies, the prevalence of CTS among adults (15–65 years old) in Western Europe ranged from 0.29% to 43%. CTS affects middle-aged active workers and is associated with high healthcare costs and a hefty economic burden. …”
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Educational migration from Tajikistan to Russia: trends and consequences by A. Kh. Rakhmonov

“…The second group consists of middle-aged and older people, skilled workers, and specialists with secondary specialized and higher education. …”
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RETROSPECTIVE STUDY OF THE EFFICACY OF LONG-TERM TREATMENT OF FELINE IDIOPATHIC CYSTITIS by Anca Bărbos, Vlad Luca, Alexandra Biriș, Radu Lăcătuș

“…Most cats affected by this pathology were neutered males (70%), Domestic ShortHair breed, middle aged (with a mean of 9 years for group A and approximately 8 years and 2 months for group B), overweight and mostly living indoors (80.95%). …”
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Outcomes of Percutaneous Coronary Intervention in Patients with Spontaneous Coronary Artery Dissection by Saber Hassan, Rohit Samuel, Andrew Starovoytov, Carolyn Lee, Eve Aymong, Jacqueline Saw

“…SCAD is an important cause of myocardial infarction (MI) in young-to-middle-aged women. Percutaneous coronary intervention (PCI) is often pursued, but outcomes compared to conservative therapy are unclear. …”
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A comprehensive analysis of trends in the burden of gout in China and globally from 1990 to 2021 by Shiwei Xie, Heng Xiao, Lei Xu, Gengwu Li, Fan Zhang, Mingwei Luo

“…Our analysis indicated that middle-aged and elderly populations, particularly males, are at higher risk for gout. …”
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Cost-Effectiveness and Budget Impact of Emerging Minimally Invasive Surgical Treatments for Benign Prostatic Hyperplasia by Bilal Chughtai, Sirikan Rojanasarot, Kurt Neeser, Dmitry Gultyaev, Stacey L. Amorosi, Neal D. Shore

“…**Background:** Benign prostatic hyperplasia (BPH) is one of the most prevalent and costly chronic conditions among middle-aged and elderly men. Prostatic urethral lift (PUL) and convective water vapor thermal therapy (WVTT) are emerging minimally invasive surgical treatments as an alternative to traditional treatment options for men with moderate-to-severe BPH. …”
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The Association Between the Onset and Ending of Volunteering on Loneliness and Perceived Social Isolation Among Older Adults: Longitudinal Evidence From the German Ageing Survey by Avery Richardson, Hans‐Helmut König, André Hajek

“…Methods Longitudinal data were obtained from Waves 5 (Year 2014) and 6 (Year 2017) of the German Ageing Survey, focusing on middle‐aged and older adults. The sample size (n = 6628) was limited to those aged 65 and above. …”
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A Cross-Sectional Study Exploring Mental Health among Patients Suffering from Dengue in Pakistani Tertiary Care Hospitals by null Faiza, Fatima Jawad, Namra Chaudhary, Mahnoor Younas, Sadaf Fatima, Fiza Ayub, Allah Bukhsh Awan, Tahir Mehmood Khan

“…According to the DASS-21 tool, patients with severe pain and high-degree fever during dengue had significant stress and anxiety symptoms, respectively, than the patients with mild or moderate pain and fever. Middle-aged patients with low literacy levels were also found to have significant associations with stress, anxiety, and depression. …”
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Metabolism-Related Adipokines and Metabolic Diseases: Their Role in Osteoarthritis by Zhang Q, Zhao YX, Li LF, Fan QQ, Huang BB, Du HZ, Li C, Li W

“…The incidence and disability rates of OA have continued to increase and seriously jeopardise the quality of life of middle-aged and older adults. However, OA is more than just a wear and tear disease; its aetiology is complex, and its pathogenesis is poorly understood. …”
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Pulmonary langerhans cell histiocytosis secondary to Marijuana use: a case report and systematic review of the literature by Ibrahim Zahid, Aruba Sohail, Roohan Tahir, Matthew Belardo, Brandon Hooks

“…Abstract Background Pulmonary Langerhans Cell Histiocytosis (PLCH) is a rare interstitial lung disease primarily affecting young to middle-aged smokers. While traditionally linked to tobacco use, there is growing evidence that cannabis use may contribute to PLCH. …”
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The road ahead: emerging therapies for primary IgA nephropathy by Edward J. Filippone, Rakesh Gulati, John L. Farber

“…A slowly progressive disease presenting in the young to middle-aged, most patients with reduced eGFR or proteinuria will progress to end-stage kidney disease (ESKD) in their lifetimes. …”
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Plasma Inflammatory Biomarkers Indicative of Aging and Overweight in Brazilian Women by Débora Nonato Miranda de Toledo, Priscilla Vilela dos Santos, Nathalia Sernizon Guimarães, Alessandra de Paula Carli, Patrícia Regina Soares de Souza, Luiza Oliveira Perucci, Caio César de Souza Alves, André Talvani

“…Specifically, plasma CK levels were similar in adults, middle-aged, and elderly women, but there was an increase in its release associated with overweight in adults and elderly women. …”
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Mixoid Liposarcoma by Azamris Azamris, Peri Handayani, Muhammad Rifki

“…Liposarcoma is malignant tumor or cancer at fatty tissue, characterized by abortif differentiated cells to lipocyte and the common type of soft tissue sarcoma, appearing slowly, enlarged, painless, nonulceratif mass submucosal at the middle age. If the early detected the cure rate can be better. …”
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Association of weight-adjusted-waist index with type 2 diabetes mellitus in Chinese urban adults: a cross-sectional study by Qingzheng Wu, Bing Li, Yuepeng Wang, Yuepeng Wang, Yue Zhang, Qian Wang, Binqi Li, Binqi Li, Wei Jing, Jing Yang, Yiming Mu

“…After adjusting for all factors with the exception of the stratified variable, this association held true in age, sex, BMI, hypertension, and hyperlipidemia subgroup and was especially pronounced in those aged <60 years, BMI ≥24 kg/m2, and males, with interactions between WWI and age, sex, and BMI (P for interaction <0.05).ConclusionWWI was positively associated with T2DM in Chinese urban adults, especially in young and middle-aged males with BMI ≥24 kg/m2.…”
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Analysis of Association of Occupational Physical Activity, Leisure-Time Physical Activity, and Sedentary Lifestyle with Hypertension according to the Adherence with Aerobic Activit... by Mikyung Ryu, Sol Lee, Ho Gym, Weon-Chil Baek, Heejin Kimm

“…We investigated the association between occupational physical activity, leisure-time physical activity, and sedentary lifestyle with hypertension by adherence with aerobic exercise in middle-aged and elderly women. Methods. A cross-sectional analysis was performed using Korea National Health and Nutrition Examination Survey (KNHANES), a nationally representative data between 2016 and 2017. …”
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Machine learning-based monitoring of land cover and reclamation plantations on coal-mined landscape using Sentinel 2 data by Mayank Pandey, Alka Mishra, Singam L. Swamy, James T. Anderson, Tarun Kumar Thakur

“…Support Vector Machine has been identified as a more accurate and effective ML algorithm compared to Random Forest and Maximum Likelihood Classifier in delineating land use and vegetation classes, particularly forests, and in distinguishing reclamation plantations into three age classes: young (4 ± 3 years), middle-aged (10 ± 2 years), and mature (15 ± 2 years). …”
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