Proteomic and transcriptomic study of brain microvessels in neonatal and adult mice. by Baptiste Porte, Clémence Chatelain, Julie Hardouin, Céline Derambure, Yasmine Zerdoumi, Michèle Hauchecorne, Nicolas Dupré, Soumeya Bekri, Bruno Gonzalez, Stéphane Marret, Pascal Cosette, Philippe Leroux

“…In parallel, comparative transcript levels were obtained using RNA hybridization microarrays and enriched biological pathways were extracted from genes exhibiting at least a two-fold change in expression. …”
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Increased Expression of SETD7 Promotes Cell Proliferation by Regulating Cell Cycle and Indicates Poor Prognosis in Hepatocellular Carcinoma. by Yuanyuan Chen, Shengsheng Yang, Jiewei Hu, Chaoqin Yu, Miaoxia He, Zailong Cai

“…Defined data on patients (n = 225) with HCC were retrieved for the further study. Tissue microarrays (TMAs) were performed using paraffin tissues with tumor and ANLTs. …”
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Deep serological profiling of the Trypanosoma cruzi TSSA antigen reveals different epitopes and modes of recognition by Chagas disease patients. by Guadalupe Romer, Leonel A Bracco, Alejandro D Ricci, Virginia Balouz, Luisa Berná, Juan C Villar, Janine M Ramsey, Melissa S Nolan, Faustino Torrico, Norival Kesper, Jaime Altcheh, Carlos Robello, Carlos A Buscaglia, Fernán Agüero

“…To optimize the serotyping performance of this molecule, we herein used a combination of immunosignaturing approaches based on peptide microarrays and serum samples from Chagas disease patients to establish a deep linear B-cell epitope profiling of TSSA.…”
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Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells. by Marcela Guzman-Ayala, Kian Leong Lee, Konstantinos J Mavrakis, Paraskevi Goggolidou, Dominic P Norris, Vasso Episkopou

“…The transcriptional responses were analysed by microarrays at different time points during activation and repression. …”
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Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. by Daniel P Depledge, Krystal J Evans, Alasdair C Ivens, Naveed Aziz, Asher Maroof, Paul M Kaye, Deborah F Smith

“…<h4>Methods/principal findings</h4>We have used customised oligonucleotide microarrays to confirm that all of the differentially distributed genes identified by genome comparisons are expressed in intracellular amastigotes, with only a few of these subject to regulation at the RNA level. …”
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Increased COX-2 Immunostaining in Urothelial Carcinoma of the Urinary Bladder Is Associated with Invasiveness and Poor Prognosis by Basim Al-Maghrabi, Wafaey Gomaa, Mohammed Abdelwahed, Jaudah Al-Maghrabi

“…UCB samples were collected before any local or systemic therapy. Tissue microarrays were designed and constructed, and TMA blocks were sliced for further immunohistochemical staining. …”
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Minería de Datos y Genómica by Valeria Burgos

“…El desarrollo de tecnologías genómicas de alto desempeño, como los microarrays y la secuenciación de próxima generación (NGS), ha hecho posible producir de manera exponencial información, con la expansión de nuestro conocimiento de las bases genéticas de varias enfermedades. …”
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MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis. by Janne M Toivonen, Raquel Manzano, Sara Oliván, Pilar Zaragoza, Alberto García-Redondo, Rosario Osta

“…Fast-twitch and slow-twitch muscles from symptomatic SOD1-G93A mice (age 90 days) and their control littermates were first studied using miRNA microarrays and then evaluated with quantitative PCR from five age groups from neonatal to the terminal disease stage (10-120 days). …”
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Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma. by Kang Wang, Wei Xing Guo, Nan Li, Chun Fang Gao, Jie Shi, Yu Fu Tang, Feng Shen, Meng Chao Wu, Shan Rong Liu, Shu Qun Cheng

“…<h4>Methods</h4>lncRNA microarrays were utilized to measure the differential expression of lncRNAs between tumor tissues and corresponding non-tumor tissues in HBV-positive hapatocellular carcinoma. uc001ncr and AX800134 were selected as candidate lncRNAs and detected in three independent cohorts containing a total of 684 participants (healthy individuals and chronic HBV patients and HBV-positive HCC patients) who were recruited between March 2011 and December 2012. …”
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Laminin N-terminus α31 is upregulated in invasive ductal breast cancer and changes the mode of tumour invasion. by Lee D Troughton, Danielle A O'Loughlin, Tobias Zech, Kevin J Hamill

“…LaNt α31 expression and distribution were analysed by immunohistochemistry in human breast tissue biopsy sections and tissue microarrays covering 232 breast cancer samples. This analysis revealed LaNt α31 to be upregulated in 56% of invasive ductal carcinoma specimens compared with matched normal tissue, and further increased in nodal metastasis compared with the tumour mass in 45% of samples. 65.8% of triple negative cases displayed medium to high LaNt α31 expression. …”
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Distinct roles of non-canonical poly(A) polymerases in RNA metabolism. by Salvatore San Paolo, Stepanka Vanacova, Luca Schenk, Tanja Scherrer, Diana Blank, Walter Keller, André P Gerber

“…To assess the level of functional redundancy between the paralogous Trf4 and Trf5 proteins and to investigate the role of the Trf4-dependent polyadenylation in vivo, we used DNA microarrays to compare gene expression of the wild-type yeast strain of S. cerevisiae with either that of trf4Delta or trf5Delta mutant strains or the trf4Delta mutant expressing the polyadenylation-defective Trf4(DADA) protein. …”
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Wolbachia infections in Anopheles gambiae cells: transcriptomic characterization of a novel host-symbiont interaction. by Grant L Hughes, Xiaoxia Ren, Jose L Ramirez, Joyce M Sakamoto, Jason A Bailey, Anne E Jedlicka, Jason L Rasgon

“…We used Affymetrix GeneChip microarrays to investigate the effect of wAlbB and wRi infection on the transcriptome of cultured Anopheles Sua5B cells, and for a subset of genes used quantitative PCR to validate results in somatically-infected Anopheles mosquitoes. …”
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SUMOYLATION AS AN EARLY ADAPTIVE MECHANISM IN THE PROTEOMIC RESPONSE OF HUMAN GERM CELLS TO SIMULATED MICROGRAVITY

“…This study analyses the effects of simulated microgravity (SμG) and hypogravity (ShG) on different pathways including SUMOylation (Small Ubiquitin-like Modifier) in human male germ cell line TCam-2, combining Reverse-Phase Protein microArrays (RPPA) and immunofluorescence. SUMO isoforms 1–4 are members of ubiquitin-related protein family that regulate transcription factors, DNA repair, cytoskeleton dynamics, stress, proliferation, and apoptosis responses[1-2. …”
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Immunohistochemical analysis of CD155 expression in triple-negative breast cancer patients. by Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie

“…<h4>Methods</h4>Using immunohistochemical staining and tissue microarrays, we analyzed the expression profiles of CD155 and PD-L1 in 61 patients with triple-negative breast cancer. …”
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Interleukin-13 receptor alpha 2 expression in tumor cells is associated with reduced disease-free survival in patients with luminal subtype invasive breast cancer by Hee Jung Kwon, Jung Eun Choi, Young Kyung Bae

“…Interleukin-13 receptor alpha 2 expressions were assessed by immunohistochemistry in tissue microarrays of 1283 invasive breast cancer samples, and associations between these expressions and clinicopathological variables and clinical outcomes were investigated. …”
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Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation. by Carrie V Breton, Kimberly D Siegmund, Bonnie R Joubert, Xinhui Wang, Weiliang Qui, Vincent Carey, Wenche Nystad, Siri E Håberg, Carole Ober, Dan Nicolae, Kathleen C Barnes, Fernando Martinez, Andy Liu, Robert Lemanske, Robert Strunk, Scott Weiss, Stephanie London, Frank Gilliland, Benjamin Raby, Asthma BRIDGE consortium

“…<h4>Methods</h4>Using Illumina HumanMethylation27 microarrays, we estimated the degree of methylation at 27,578 distinct DNA sequences located primarily in gene promoters using whole blood DNA samples from the Childhood Asthma Management Program (CAMP) subset of Asthma BRIDGE childhood asthmatics (n = 527) ages 5-12 with prenatal smoking exposure data available. …”
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Tumor-infiltrating B cells produce tumor-specific antibodies and may contribute to suppressing tumor in head and neck squamous cell carcinoma by Junsei Sameshima, Hu Chen, Naoki Kaneko, Lijing Yan, Shiho Yokomizo, Tomoki Sueyoshi, Haruki Nagano, Taiki Sakamoto, Shoichi Tanaka, Yasuyuki Maruse, Taichi Hattori, Ryoji Kitamura, Yoshikazu Hayashi, Takashi Maehara, Shinsuke Fujii, Tamotsu Kiyoshima, Thomas Guy, Zivile Giedraityte, Wataru Kumamaru, Masafumi Moriyama, Shintaro Kawano

“…These ASCs exhibited a low somatic hypermutation frequency, indicating that they are likely activated through extrafollicular response rather than germinal center response. Protein microarrays with recombinant antibodies mimicking TIL-Bs secretory antibodies and serum antibodies revealed several antigens highly expressed in tumor cells. …”
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Mismatch repair enzyme expression in primary and castrate resistant prostate cancer by Belinda Nghiem, Xiaotun Zhang, Hung-Ming Lam, Lawrence D. True, Ilsa Coleman, Celestia S. Higano, Peter S. Nelson, Colin C. Pritchard, Colm Morrissey

“…Objective: Although the utility of immunohistochemistry (IHC) for assessing mismatch repair (MMR) protein expression has been demonstrated in solid tumors including primary prostate cancer (PCa), its utility has not been assessed in castration-resistant PCa (CRPC). Methods: Tissue microarrays were constructed from 127 radical prostatectomies and 155 CRPC metastases from 50 patients. …”
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Immunohistochemical TTF-1 and Napsin a Expression in Gastrointestinal Adenocarcinomas—Low Frequency but an Important Pitfall by Petar Noack, Claudia Grosse, Simon Eschemann, Bastian Dislich, Rupert Langer

“…<b>Methods</b>: Buffered formalin-fixed paraffin-embedded tumor tissues from 854 patients with primary resected gastrointestinal and esophageal carcinomas were placed in tissue microarrays (TMAs) for investigation. Between two and six tumor cores were analyzed for each case. …”
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Purification and Epitope Mapping of Jug r 4, a Major Walnut Allergen by Stephen A. Y. Gipson, Jacqueline B. Nesbit, Lauren T. Swientoniewski, Stephen I. Rogers, S. Shahzad Mustafa, Stephen C. Dreskin, Suzanne S. Teuber, Hsiaopo Cheng, Soheila J. Maleki

“…Sera from individuals allergic to both peanuts and walnuts were utilized to examine peptide microarrays comprising synthetic overlapping 15 mer peptides, offset by five amino acids, of Ara h 3 and Jug r 4. …”
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