Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. by Amanda L Evans, Tiago Faial, Michael J Gilchrist, Thomas Down, Ludovic Vallier, Roger A Pedersen, Fiona C Wardle, James C Smith

“…<h4>Methodology/principal findings</h4>Here we use chromatin immunoprecipitation and mouse promoter microarrays to identify targets of Brachyury in embryoid bodies formed from differentiating mouse ES cells. …”
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Revealing new mouse epicardial cell markers through transcriptomics. by Lars Bochmann, Padmini Sarathchandra, Federica Mori, Enrique Lara-Pezzi, Domenico Lazzaro, Nadia Rosenthal

“…<h4>Methodology</h4>Using laser capture microscopy, we isolated the epicardial layer from the adult murine heart before or after cardiac infarction in wildtype mice and mice expressing a transgenic IGF-1 propeptide (mIGF-1) that enhances cardiac repair, and analyzed the transcription profile using DNA microarrays.<h4>Principal findings</h4>Expression of epithelial genes such as basonuclin, dermokine, and glycoprotein M6A are highly enriched in the epicardial layer, which maintains expression of selected embryonic genes involved in epicardial development in mIGF-1 transgenic hearts. …”
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Integrated analyses of copy number variations and gene expression in lung adenocarcinoma. by Tzu-Pin Lu, Liang-Chuan Lai, Mong-Hsun Tsai, Pei-Chun Chen, Chung-Ping Hsu, Jang-Ming Lee, Chuhsing Kate Hsiao, Eric Y Chuang

“…Identification of prognostic biomarkers for lung cancer using gene expression microarrays poses a major challenge in that very few overlapping genes have been reported among different studies. …”
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Identification and analysis of genetic variations in pri-miRNAs expressed specifically or at a high level in sheep skeletal muscle. by Wei Zhang, Limin Wang, Ping Zhou, Guangchao Song, Min Shen, Shangquan Gan, Guoqing Shi

“…In this study, we used microarrays to detect 261 miRNAs that are expressed in sheep skeletal muscle. …”
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Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. by Ludovic Tailleux, Simon J Waddell, Mattia Pelizzola, Alessandra Mortellaro, Michael Withers, Antoine Tanne, Paola Ricciardi Castagnoli, Brigitte Gicquel, Neil G Stoker, Philip D Butcher, Maria Foti, Olivier Neyrolles

“…<h4>Background</h4>Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. …”
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Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes. by Hong Lin, Vibhor Gupta, Matthew D Vermilyea, Francesco Falciani, Jeannie T Lee, Laura P O'Neill, Bryan M Turner

“…Embryonic stem (ES) cells derived from the ICM of female mice have two active X chromosomes, one of which is inactivated as the cells differentiate in culture, providing a powerful model system to study the dynamics of X inactivation. Using microarrays to assay expression of X-linked genes in undifferentiated female and male mouse ES cells, we detect global up-regulation of expression (1.4- to 1.6-fold) from the active X chromosomes, relative to autosomes. …”
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iCLIP predicts the dual splicing effects of TIA-RNA interactions. by Zhen Wang, Melis Kayikci, Michael Briese, Kathi Zarnack, Nicholas M Luscombe, Gregor Rot, Blaž Zupan, Tomaž Curk, Jernej Ule

“…The predictions were validated in an unbiased manner using splice-junction microarrays, RT-PCR, and minigene constructs, which showed that TIA proteins maintain splicing fidelity and regulate alternative splicing by binding exclusively downstream of 5' splice sites. …”
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Accurate distinction of pathogenic from benign CNVs in mental retardation. by Jayne Y Hehir-Kwa, Nienke Wieskamp, Caleb Webber, Rolph Pfundt, Han G Brunner, Christian Gilissen, Bert B A de Vries, Chris P Ponting, Joris A Veltman

“…Hundreds of CNVs can be detected in any individual genome using genomic microarrays or whole genome sequencing technology, but their phenotypic consequences are still poorly understood. …”
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Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma. by Joseph M Catanzaro, Jennifer L Guerriero, Jingxuan Liu, Erica Ullman, Namratha Sheshadri, John J Chen, Wei-Xing Zong

“…Immunohistochemical analysis of SCCA expression was performed on tissue microarrays containing breast tumor tissues (n = 1,360) and normal breast epithelium (n = 124). …”
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Update on recent hot issues and progress of acute kidney injury by Liang Xin-ling, Chen Yuan-han, Wu Yan-hua

“…Multiple markers or microarrays is alternative direction， in spit of cost limitation. …”
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Epithelial and stromal microRNA signatures of columnar cell hyperplasia linking Let-7c to precancerous and cancerous breast cancer cell proliferation. by Sofie Björner, Paul A Fitzpatrick, Yaoyong Li, Craig Allred, Anthony Howell, Anita Ringberg, Håkan Olsson, Crispin J Miller, Håkan Axelson, Göran Landberg

“…Here we have defined novel epithelial as well as stromal miRNA signatures from columnar cell hyperplasia lesions compared to normal terminal duct lobular units by using microdissection and miRNA microarrays. Let-7c were among the identified downregulated epithelial miRNAs and its functions were delineated in unique CCH derived cells and breast cancer cell line MCF-7 suggesting anti-proliferative traits potentially due to effects on Myb and ERα. …”
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Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis. by Laia Ribas, Ming-Shi Li, Benjamin J Doddington, Jacques Robert, Judith A Seidel, J Simon Kroll, Lyle B Zimmerman, Nicholas C Grassly, Trenton W J Garner, Matthew C Fisher

“…Using temporal expression-profiling by microarrays and qRT-PCR, we characterise this response in the main amphibian lymphoid tissue, the spleen. …”
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FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms. by Darren C Tomlinson, Euan W Baxter, Paul M Loadman, Mark A Hull, Margaret A Knowles

“…We used expression microarrays to assess changes in gene expression downstream of these signalling cascades. …”
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Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study by Zi-Qian Liang, Li Gao, Jun-Hong Chen, Wen-Bin Dai, Ya-Si Su, Gang Chen

“…Combining the data from in-house tissue microarrays and high-throughput datasets, we identified the expression level of CCDC80 in OVCA. …”
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From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity. by Geraldine Mulley, Michael L Beeton, Paul Wilkinson, Isabella Vlisidou, Nina Ockendon-Powell, Alexia Hapeshi, Nick J Tobias, Friederike I Nollmann, Helge B Bode, Jean van den Elsen, Richard H ffrench-Constant, Nicholas R Waterfield

“…Here we use RNA-seq, proteomics and phenotype microarrays to examine temperature dependent differences in transcription, translation and phenotype of P. asymbiotica at 28°C versus 37°C, relevant to the insect or human hosts respectively. …”
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Extended receptor repertoire of an adenovirus associated with human obesity. by A Manuel Liaci, Naresh Chandra, Sharvani Munender Vodnala, Michael Strebl, Pravin Kumar, Vanessa Pfenning, Paul Bachmann, Rémi Caraballo, Wengang Chai, Emil Johansson, Mikael Elofsson, Ten Feizi, Yan Liu, Thilo Stehle, Niklas Arnberg

“…Sialic acids are recognized at the same binding site used by other HAdVs of species D such as HAdV-D37. Using glycan microarrays, we demonstrate that HAdV-D36 displays a binding preference for glycans containing a rare sialic acid variant, 4-O,5-N-diacetylneuraminic acid, over the more common 5-N-acetylneuraminic acid. …”
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The Impact of Antenatal and Postnatal Factors on the Development of the Pulmonary Microvasculature in Preterm Infants by Raluca Chirculescu, Ruxandra Viorica Stănculescu, Paul Cristian Bălănescu, Gheorghe Peltecu

“…After selecting the cases from the autopsy database, two lung tissue microarrays were created. Histological slides were stained using the hematoxylin and eosin technique to precisely capture the microscopic details. …”
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Dynamics of the genetic structure of dairy cattle population in the Sverdlovsk region by Lihodeevskiy G.A., Bogatova P.S., Lihodeevskaya O.E., Modorov M.V.

“…Using GGP Bovine 150K and Bovine 50K DNA microarrays, we determined the genotypes of over 1,000 cows born between 2007 and 2022, belonging to nine agricultural enterprises in the Sverdlovsk region. …”
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One-sample missing DNA-methylation value imputation by Christelle Kemda Ngueda, Julia Palm, Flavia Remo, André Scherag, Lutz Leistritz

“…In addition, the accuracy of imputation depends in general on the density of CpG sites on DNA-methylation microarrays and increases as the CpG site density increases. …”
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Microsatellite Instability and Loss of Heterozygosity in CCND1 Microsatellite loci at Chr.11q13 in OSCC Patients with Therapeutic Validation by Seema Gupta, Shally Batham, Biswajit Maity

“…Molecular laboratory techniques like microarrays, microsatellites, and single-nucleotide polymorphisms (SNPs) have created new opportunities for diagnosing diseases, identifying chromosomal aberrations, and detecting point mutations for medical verification. …”
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