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1801
Kinetic changes in microglia-related retinal transcripts in experimental autoimmune uveoretinitis (EAU) of B10.RIII mice
Published 2025-02-01“…Genome-wide transcriptional profiles of EAU (day 7, 14 or 21 after immunization) and of control retinas were generated using DNA-microarrays and bioinformatic data mining. Microglia-associated transcripts were identified. …”
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1802
Unique reporter-based sensor platforms to monitor signalling in cells.
Published 2012-01-01“…The methodology uses two robust and easily accessible detection platforms; quantitative real-time PCR for quantitative analysis and DNA microarrays for parallel, higher throughput analysis.…”
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1803
Quantitative measurement of allele‐specific protein expression in a diploid yeast hybrid by LC‐MS
Published 2012-08-01“…Differential allele‐specific expression (ASE), in which the expression of one allele differs from another in a diploid, implies the presence of cis‐acting regulatory variation. While microarrays and high‐throughput sequencing have enabled genome‐wide measurements of transcriptional ASE, methods for measurement of protein ASE (pASE) have lagged far behind. …”
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1804
LMX1B Activated Circular RNA GFRA1 Modulates the Tumorigenic Properties and Immune Escape of Prostate Cancer
Published 2022-01-01“…In this study, circRNA microarrays using four pairs of PCa tissues were utilized to show that circGFRA1 was upregulated in PCa tumor tissues. …”
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1805
Transcriptome and Proteome Research in Veterinary Science: What Is Possible and What Questions Can Be Asked?
Published 2012-01-01“…This review gives an overview on the methods currently available for transcriptome analysis, that is, microarrays, Ref-Seq, quantitative PCR arrays and discusses their potentials and limitations. …”
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1806
Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells.
Published 2014-01-01“…A comparison of SLPI mRNA levels by gene profiling using microarrays and RT-PCR did not detect major differences in SLPI gene expression between the 4T1 and 4T1.2 cells indicating that SLPI secretion is regulated at the protein level. …”
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1807
Erythrocyte phospho-signalling is dynamically altered during infection with Plasmodium falciparum
Published 2020-09-01“…This was achieved through the use of antibody microarrays containing >800 antibodies directed against human signalling proteins, which enabled us to interrogate the status of host erythrocyte signalling pathways at the ring, trophozoite and schizont stages of parasite development. …”
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1808
Effects of pregnancy on breast cancer immunology: immune biomarker and TIL quantification
Published 2025-05-01“…We constructed Tissue Microarrays (TMA) of tumor specimens from 126 pregnant breast cancer (BC) patients and examined standard BC markers such as ER, PR, Ki67, HER2, tumor infiltrating lymphocytes (TILs), and immunomarkers HLA class I, HLA-G, PD-L1, TIGIT and Nectin-4. …”
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1809
Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array...
Published 2022-01-01“…The UK Biobank genotyped about 500k participants using Applied Biosystems Axiom microarrays. Participants were subsequently sequenced by the UK Biobank Exome Sequencing Consortium. …”
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1810
Role of laboratory biomarkers in monitoring and prediction of the effectiveness of treatment of rheumatic diseases using genetically engineered drugs
Published 2014-03-01“…In addition to the conventional uniplex immunodiagnostics techniques, multiplex analysis of marker, which is based on genetic, transcriptomic and proteomic technologies using DNA and protein microarrays, polymerase chain reaction, and flow cytometry, is becoming increasingly widespread. …”
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1811
SNPstream® UHT: Ultra-High Throughput SNP Genotyping for Pharmacogenomics and Drug Discovery
Published 2002-06-01“…The system employs oligonucleotide microarrays manufactured in a 384-well format on a novel glass-bottomed plate. …”
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1812
The Response of Enterococcus faecalis V583 to Chloramphenicol Treatment
Published 2010-01-01“…No specific genes coding for chloramphenicol resistance has been recognized in V583. We used microarrays to identify genes and mechanisms behind the tolerance to chloramphenicol in V583, by comparison of cells treated with subinhibitory concentrations of chloramphenicol and untreated V583 cells. …”
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1813
Global gene expression analysis of murine limb development.
Published 2011-01-01“…We used whole-genome microarrays to identify genes with differential expression at 5 stages of limb development (E9.5 to 13.5), during fore- and hind-limb patterning. …”
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1814
Cell cycle-specified fluctuation of nucleosome occupancy at gene promoters.
Published 2006-09-01“…Using FAIRE (formaldehyde-assisted isolation of regulatory elements) and whole-genome microarrays, we examined changes in nucleosome occupancy throughout the mitotic cell cycle in synchronized populations of S. cerevisiae. …”
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1815
DnaC inactivation in Escherichia coli K-12 induces the SOS response and expression of nucleotide biosynthesis genes.
Published 2008-08-01“…<h4>Methodology/principal findings</h4>DNA microarrays were used to measure mRNA steady-state levels in initiation-deficient dnaA46 and dnaC2 bacteria at permissive and non-permissive temperatures and their expression profiles were compared to MG1655 wildtype cells. …”
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1816
Examining the Genomic Influence of Skin Antioxidants In Vitro
Published 2010-01-01“…The resulting treated cells were then examined using human gene microarrays supplied by Agilent. These chips typically have somewhere on the order of 30,000 individual genes which are expressed in the human genome. …”
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1817
Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.
Published 2010-10-01“…We then employed two approaches to discover miR-294 targets in mouse ES cells: transcriptome profiling using microarrays and a biochemical approach to isolate mRNA targets associated with the Argonaute2 (Ago2) protein of the RISC (RNA Induced Silencing Complex) effector, followed by RNA-sequencing. …”
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1818
Novel Hypomorphic Mutation in FANCD2 Gene Observed in a Fetus with Multiple Congenital Anomalies
Published 2016-01-01“…The case illustrates that patients/families affected by rare monogenic disorders may benefit from application of modern technologies like microarrays and NGS.…”
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1819
Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression
Published 2007-05-01“…Our results are highly reproducible, being confirmed using two different experimental setups that entail different microarrays and different controls. Our results indicate that the CSN acts as a transcriptional repressor during development of Drosophila, resulting in achronic gene expression in the csn mutants. …”
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1820
Personalized risk stratification in colorectal cancer via PIANOS system
Published 2025-07-01“…It effectively differentiates high-risk from low-risk patients, outperforms 105 existing models, and demonstrates robust performance across technologies like microarrays and RNA sequencing. PIANOS-based stratification is validated as an independent predictor of disease-free survival. …”
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