Effects of tumour-associated macrophages on cardia carcinoma progression by Zhixiong Zhang, Zihong Xu, Yaowu Cai, Xintong Chen, Chaoqing Huang, Xuefeng Xu

“…Methods Cancer tissue and pericancer tissue samples from 80 patients with cardia carcinoma who underwent D2 radical surgery between January 2014 and January 2015 at Putian First Hospital were selected. Tissue microarrays were fabricated, and immunohistochemistry technology was used to detect the infiltration of TAMs (CD163 as a marker) and to analyse their relationship with the clinicopathological characteristics of the patients. …”
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Decoding the prognostic landscape of LUAD: the interplay between N6-methyladenosine modification and immune microenvironment by Quan Chen, Quan Chen, Weijun Wan, Qing Zhao, Juan Li, Juan Li, Yanli Xiong, Yanli Xiong, Yuchuan Yuan, Lu Tang, Xiaofeng Wu, Wei Xing, Wei Guo, Di Lu, Luoquan Ao, Xiang Xu, Xiang Xu, Xiang Xu, Xiang Ao, Xiang Ao, Xiang Ao

“…These findings were validated by two independent databases and LUAD tissue microarrays. METTL3 was found to impact the mRNA expression of these genes, with METTL3 deficiency abolishing these interactions. …”
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Evaluating Biocompatibility: From Classical Techniques to State-of-the-Art Functional Proteomics by Ana Nuño-Soriano, Carlota Arias-Hidalgo, Enrique Montalvillo, Rafael Góngora, Ángela-Patricia Hernández, Pablo Juanes-Velasco, Manuel Fuentes

“…This review presents high-throughput functional proteomics approaches, focused on protein microarrays and mass spectrometry techniques, for the evaluation of biocompatibility in the new era of biomedicine.…”
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Genetic Dissection of Learning and Memory in Mice by Yann S. Mineur, Wim E. Crusio, Frans Sluyter

“…Next, we briefly review more recently developed techniques, such as microarrays and RNA interference. In addition, we focus on gene-environment interactions and endophenotypes. …”
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The Impact of “Omic” and Imaging Technologies on Assessing the Host Immune Response to Biodefence Agents by Julia A. Tree, Helen Flick-Smith, Michael J. Elmore, Caroline A. Rowland

“…Namely, the use of “omic” technologies (next generation sequencing, DNA, and protein microarrays) for dissecting the underlying host response to infection at the molecular level; optical imaging techniques (flow cytometry and fluorescence microscopy) for assessing cellular responses to infection; and biophotonic imaging for visualising the infectious disease process. …”
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IL-6 is a prognostic biomarker in patients with advanced esophageal squamous cell carcinoma received with PD-1 inhibitors by Ping Huang, Manyi Zhao, Jianhong Xia, Hongliang Li, Junxia Sun, Xin Li, Chunsheng Yang, Guangyi Gao, Wenhang Zhou, Meifeng Zhong, Hongmei Yong

“…CD8, IL-6, and PD-L1 expression in ESCC tissue microarrays were measured using immunohistochemistry, and then the tumor microenvironment was classified. …”
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Increased adherence and expression of virulence genes in a lineage of Escherichia coli O157:H7 commonly associated with human infections. by Galeb S Abu-Ali, Lindsey M Ouellette, Scott T Henderson, David W Lacher, James T Riordan, Thomas S Whittam, Shannon D Manning

“…Whole-genome 70-mer oligo microarrays, which probe for 6088 genes from O157:H7 Sakai, O157:H7 EDL 933, pO157, and K12 MG1655, detected significant differential expression between clades in 604 genes following co-incubation with epithelial cells for 30 min; 186 of the 604 genes had a >1.5 fold change difference. …”
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Value of Optical Genome Mapping (OGM) for Diagnostics of Rare Diseases: A Family Case Report by Kovanda A, Miljanović O, Lovrečić L, Maver A, Hodžić A, Peterlin B

“…Since its introduction in 2021, we have used OGM for the testing of facioscapulohumeral muscular dystrophy 1, characterization and resolution of variants identified by other technologies such as microarrays, exome and genome next-generation sequencing, karyotyping, as well as testing of rare disease patients in whom no genetic cause could be identified using these methods.…”
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Public Database-based Study to Explore the Expression and Role of DDB1 
in Lung Adenocarcinoma by Xinkai ZOU, Ziyi HE, Yanfei ZHANG, Yi HU, Xiaomin WANG, Zhongjie WU

“…Single cell analysis showed that DDB1 was mainly expressed in T cells, alveolar macrophages and dendritic cells. Tissue microarrays confirmed that overall survival was shorter in the DDB1 high expression group (P<0.001), and Cox multifactorial analysis showed that DDB1 was an independent predictor of LUAD prognosis. …”
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Dual-targeting and steric hindrance resolution in HER2 IHC: a novel approach to improve diagnostic sensitivity by Li Luo, Xi Zhang, Linqiong Chen, Zhuohan Chen, Yuchen Wang, Kaihao Huang, Xiaoyun Lin, Hongxiang Zhu, Wangqi Du

“…Additionally, significantly higher HER2 scores were observed in most BC tissues on tissue microarrays (TMAs) compared to those diagnosed using the traditional method. …”
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Chemical and Enzymatic Synthesis of DisialylGb5 and Other Sialosides for Glycan Array Assembly and Evaluation of Siglec-Mediated Immune Checkpoint Inhibition by Kuo-Shiang Liao, Yixuan Zhou, Cinya Chung, Chih-Chuan Kung, Chien-Tai Ren, Chung-Yi Wu, Yi-Wei Lou, Po-Kai Chuang, Balázs Imre, Yves S. Y. Hsieh, Chi-Huey Wong

“…In this study, efficient chemo-enzymatic and programmable one-pot methods were explored for the synthesis of DSGb5 and related sialosides for assembly of glycan microarrays and evaluation of binding specificity toward Siglecs-7, 9, 10, and 15 associated with immune checkpoint inhibition. …”
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Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array. by Caroline May, Eckhard Nordhoff, Swaantje Casjens, Michael Turewicz, Martin Eisenacher, Ralf Gold, Thomas Brüning, Beate Pesch, Christian Stephan, Dirk Woitalla, Botond Penke, Tamás Janáky, Dezső Virók, László Siklós, Jozsef I Engelhardt, Helmut E Meyer

“…These results led us to perform a case-control study using human protein microarrays to identify the antibody profiles of serum samples from 20 ALS patients and 20 healthy controls. …”
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Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. by Gustavo Gomez, Jae-Hyung Lee, Matthew B Veldman, Jing Lu, Xinshu Xiao, Shuo Lin

“…Several novel genes expressed in vasculature have been identified through transcriptional profiling of zebrafish embryos overexpressing etsrp by microarrays. Here we re-examined this transcriptional profile by Illumina RNA-sequencing technology, revealing a substantially increased number of candidate genes regulated by etsrp. …”
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Disruption of DMD gene leads to altered calcium homeostasis and metabolic shift impacting gastric Cancer cell proliferation and migration by Xiaodong Zou, Tong Wu, Tao Su, Hui Xiao, Chuyan Ni, Lijuan Hu, Wenchu Lin, Weilin Chen, Richard D Ye, Jianjiao Lin, Li Xiang

“…Methods We validated DMD gene expression levels in the TIMER2.0 database and human gastric cancer tissue microarrays and constructed gastric precancerous lesion mouse models and DMD gene knockout and overexpression cell lines to investigate the role of DMD gene in gastric cancer development. …”
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α5-nAChR/NETO2 contributed to chronic stress-promoted lung adenocarcinoma progression by Jingting Wang, Jiaying Cai, Zengping Wang, Shuran Yang, Jing Wang, Yanfei Jia, Haiji Sun, Xiaoli Ma

“…Methods RNA-Seq and bioinformatics database were used for analyzing the expression as well as correlation of α5-nAChR, together with NETO2 in LUAD. α5-nAChR and NETO2 expression were detected using immunohistochemistry in LUAD tissue microarrays, chronic restraint stress (CRS) and chronic unpredictable stress (CUMS) mice tissues. …”
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An Overview of Advancements in Proteomic Approaches to Enhance Livestock Production and Aquaculture by Jakree Jitjumnong, Anukul Taweechaipaisankul, Jou-Ching Lin, Supatirada Wongchanla, Schwann Chuwatthanakhajorn, Chih-Jen Lin, Luu Tang Phuc Khang, Nguyen Vu Linh, Papungkorn Sangsawad, Nguyen Dinh-Hung, Pin-Chi Tang, Tossapol Moonmanee

“…Key methods, including mass spectrometry, two-dimensional gel electrophoresis, and protein microarrays, enable researchers to analyze protein complexity in biological systems. …”
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Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes by Virginia Tajadura-Ortega, Wengang Chai, Lauren A. Roberts, Yibing Zhang, Antonio Di Maio, Alexiane C. Decout, Benedita A. Pinheiro, Angelina S. Palma, Gian De Nicola, Lucia Riaposova, Belen Gimeno-Molina, Yun S. Lee, Hongzhi Cao, Vladimir Piskarev, Yukie Akune, Tiago R. D. Costa, Himani Amin, Lynne Sykes, Phillip R. Bennett, Julian R. Marchesi, Ten Feizi, Yan Liu, David A. MacIntyre

“…Using customised glycan microarrays, we establish glycan interaction profiles of vaginal bacteria implicated in reproductive health. …”
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Comprehensive analysis of single-cell and bulk RNA sequencing data unveils antigen-presenting and processing fibroblasts and establishes a predictive model in gastric cancer by Chenggang Zhang, Fangqi Chen, Jie Li, Yixuan He, Juan Sun, Zicheng Zheng, Guanmo Liu, Yihua Wang, Weiming Kang, Xin Ye

“…Finally, the immunohistochemical results of GC tissue microarrays revealed higher expression of CPVL, ZNF331, and TPP1, and lower expression of LGALS9 and TNFAIP2 in GC compared to adjacent normal tissues. …”
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Electrochemical Strategies for MicroRNA Quantification Leveraging Amplification and Nanomaterials: A Review by Alexander Hunt, Gymama Slaughter

“…However, conventional detection methods, such as Northern blotting, RT-PCR, and microarrays, are limited by low sensitivity, lengthy protocols, and limited specificity. …”
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Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus by Xianglu Li, William G. Fusco, Keun S. Seo, Kenneth W. Bayles, Erin E. Mosley, Mark A. McGuire, Gregory A. Bohach

“…HEp-2 cell monolayers were cocultured with intracellular Staphylococcus aureus, and changes in gene expression were profiled using DNA microarrays. Intracellular S. aureus affected genes involved in cellular stress responses, signal transduction, inflammation, apoptosis, fibrosis, and cholesterol biosynthesis. …”
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