Associations between pathophysiological traits and symptom development in retrospective analysis of V30M and V122I transthyretin amyloidosis by Sameer U. Kini, Ha My Thi Vy, Madhav Subramanian, Parasuram M. Krishnamoorthy, Son Q. Duong, Ghislain Rocheleau, Jagat Narula, Ron Do, Girish N. Nadkarni

“…This retrospective analysis of microarray and biobank data helped establish clinical biomarkers for early hATTR detection. …”
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Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors by Michael Hoffmeister, Hermann Brenner, Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Julien Taieb, David Tougeron, Robyn L Ward, Marco Vitellaro, Thierry André, Pierre Laurent-Puig, Jitendra Jonnagaddala, Francesca Bergamo, Raghav Sundar, Claire Gallois, Michael J Overman, Jakob Nikolas Kather, Lisa Salvatore, Romain Cohen, Rossana Intini, Priya Jayachandran, Miriam Koopman, Javier Ros, Marwan Fakih, Vincenzo Nasca, Giacomo Mazzoli, Jeanine M L Roodhart, Filippo Ghelardi, Elena Elez, Durgesh Wankhede, Marta Ligero, Joseph Zhao, Koen Zwart, Jeroen Derksen, Nicholas Hawkins, Javier Carmona

“…Finally, we explored two public microarray and RNA-seq datasets from patients with non-metastatic or metastatic MSI-H CRC to gain translational insights on the association between sex, BRAF status and immune contextures/ICI efficacy.Results Although no differences were observed between females and males either overall or in the BRAF wild-type cohort, male sex was associated with inferior progression-free survival (PFS) and overall survival (OS) in the BRAF mutated cohort (in multivariable models, HR for PFS: 1.79, 95% CI: 1.13 to 2.83, p=0.014, and for OS: 2.33, 95% CI: 1.36 to 3.98, p=0.002). …”
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A Transcriptomic Approach to Sex Differences in Calcific Aortic Valve Stenosis in Patients with a Tricuspid Aortic Valve by Emma Le Nezet, MSc, Rose Tam, MSc, Zhonglin Li, MSc, Nathalie Gaudreault, BSc, Patrick Mathieu, MD, MSc, Nancy Côté, PhD, Isabelle Guisle, PhD, Sébastien Thériault, MD, MSc, Yohan Bossé, PhD, Marie-Annick Clavel, DVM, PhD

“…Methods: A total of 300 valves were collected, and genomewide gene expression was quantified using a microarray on 240. Among these, 62 female patients were matched with 62 male patients, for age (within 2 years), body mass index (within 2 kg/m2), arterial pressure (within 10/5 mm Hg), diabetes (exact), hypertension (exact), and calcific aortic valve stenosis severity. …”
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Genome-wide association study reveals the genetic mechanism of wing bone strength in Cornish White by Longyu Zhuang, Yuanhang Shi, Xuefeng Shi, Caiyun Jiang, Lin Xuan, Bingxin Luo, Honglei Jin, Runzhe Wang, Jiahui Lai, Guangqi Li, Yiyuan Yan, Guiqin Wu, Guiyun Xu, Jiangxia Zheng

“…A genome-wide association study (GWAS) was performed and a linear mixed model was used to analyze 39,000 SNPs from a self-developed broiler microarray. The genetic parameters of the traits were calculated. …”
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Analysis of Result Variability from High-Density Oligonucleotide Arrays Comparing Same-Species and Cross-Species Hybridizations by J.D. Chismar, T. Mondala, H.S. Fox, E. Roberts, D. Langford, E. Masliah, D.R. Salomon, S.R. Head

“…There exists a significant limitation in the variety of organisms for which microarrays have been developed because of a lack of genomic sequence data. …”
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Comprehensive Expression Profiling and Molecular Basis of CDC28 Protein Kinase Regulatory Subunit 2 in Cervical Cancer by Li Qin, Xiaoqiong Luo, Xiao Qin, Hongbao Huang, Lianling Zhang, Shengcai Chen, Xiaoqin Wu, Bingsheng Huang, Jian Pan, Jingxi Wei

“…Herein, taking advantage of massive genetics data from multicenter RNA-seq and microarrays, we were the first group to perform tissue microarrays for CKS2 in cervical cancer. …”
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Genome-scale validation of deep-sequencing libraries. by Dominic Schmidt, Rory Stark, Michael D Wilson, Gordon D Brown, Duncan T Odom

“…We show how commercially available genomic microarrays can be used to maximize the efficiency of library creation and quickly generate reliable preliminary data on a chromosomal scale in advance of deep sequencing. …”
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Applicability of epigenetic age models to next-generation methylation arrays by Leonardo D. Garma, Miguel Quintela-Fandino

“…As new methylation microarrays are developed and older models discontinued, existing epigenetic clocks might become obsolete. …”
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NONO regulates m5C modification and alternative splicing of PTEN mRNAs to drive gastric cancer progression by Gaichao Zhao, Ruochen liu, Lingjun Ge, Dan Qi, Qishu Wu, Zini Lin, Houji Song, Liping Zhong, Hongjuan Cui

“…Methods We analyzed tissue microarrays and transcriptomic data derived from gastric cancer, with an emphasis on RNA splicing and m5C regulators. …”
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The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice. by Lee Smith, John Willan, Nick Warr, Frances A Brook, Michael Cheeseman, Richard Sharpe, Pam Siggers, Andy Greenfield

“…We have previously used DNA microarrays to screen for novel genes controlling the developmental fate of the indifferent embryonic mouse gonad. …”
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Co-regulation of the DAF-16 target gene, cyp-35B1/dod-13, by HSF-1 in C. elegans dauer larvae and daf-2 insulin pathway mutants. by Wendy B Iser, Mark A Wilson, William H Wood, Kevin Becker, Catherine A Wolkow

“…First, we used transcriptional microarrays to identify target genes regulated non-autonomously by IIS in the intestine or in neurons. …”
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Alliin, a Garlic (Allium sativum) Compound, Prevents LPS-Induced Inflammation in 3T3-L1 Adipocytes by Saray Quintero-Fabián, Daniel Ortuño-Sahagún, Manuel Vázquez-Carrera, Rocío Ivette López-Roa

“…Furthermore, the gene expression profile by microarrays evidentiate an upregulation of genes involved in immune response and downregulation of genes related with cancer. …”
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VEIKIANTIS GENOMAS - VISUMINIS POŽYMIS: DABARTIES ŽVILGSNIS Į GENETIKĄ by Jonas Rubikas

“…Keywords: genome, genomics, DNA microarrays, proteome. …”
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VEIKIANTIS GENOMAS - VISUMINIS POŽYMIS: DABARTIES ŽVILGSNIS Į GENETIKĄ by Jonas Rubikas

“…Keywords: genome, genomics, DNA microarrays, proteome. …”
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VEIKIANTIS GENOMAS - VISUMINIS POŽYMIS: DABARTIES ŽVILGSNIS Į GENETIKĄ by Jonas Rubikas

“…Keywords: genome, genomics, DNA microarrays, proteome. …”
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VEIKIANTIS GENOMAS - VISUMINIS POŽYMIS: DABARTIES ŽVILGSNIS Į GENETIKĄ by Jonas Rubikas

“…Keywords: genome, genomics, DNA microarrays, proteome. …”
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Expression of Wnt/β-Catenin Signaling Pathway and Its Regulatory Role in Type I Collagen with TGF-β1 in Scleral Fibroblasts from an Experimentally Induced Myopia Guinea Pig Model by Min Li, Ying Yuan, Qingzhong Chen, Rao Me, Qing Gu, Yunjie Yu, Minjie Sheng, Bilian Ke

“…Wnt isoforms were examined using genome microarrays. Scleral fibroblasts from FDM group and self-control (SC) group were cultured. …”
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RNA profiling and immunohistochemistry analyses of circRNAs in imatinib-resistant gastrointestinal stromal tumors by Hanxing Tong, Ning Jia, Wenyang Li, Jingjing Xu, Qiuyue Li, Xiaomeng He, Huaqin Sun, Christopher Corpe, Jin Wang

“…Methods To identify the factors that are responsible for imatinib resistance, we investigated the differentially expressed mRNAs and circRNAs in imatinib-naïve and imatinib-resistant GISTs via ceRNA microarrays. The expression levels of circ-BRIP1, circ-EPHB4 and their host genes were validated via quantitative real-time PCR analyses and formalin-fixed and paraffin-embedded (FFPE) tissue microarrays (TMAs). …”
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Heterogeneity in Breast Cancer and the Problem of Relevance of Findings by M. Aubele, M. Werner

“…Emerging new techniques such as microarrays, will provide us with a wealth of additional data over the next years. …”
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Impact of MiRNAs on Wnt-related gene activity in breast cancer by Tomasz Sirek, Agata Sirek, Nikola Zmarzły, Marcin Opławski, Katarzyna Król-Jatręga, Dariusz Boroń, Michał Chalcarz, Piotr Ossowski, Konrad Dziobek, Damian Strojny, Joanna Szymańska, Julia Gajdeczka, Przemysław Borawski, Kacper Boroń, Beniamin Oskar Grabarek

“…Expression profile of Wnt-related genes was assessed with mRNA microarrays and reverse transcription quantitative polymerase chain reaction (RT-qPCR). …”
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