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1441
Differentiating Branch Duct and Mixed IPMN in Endoscopically Collected Pancreatic Cyst Fluid via Cytokine Analysis
Published 2012-01-01“…Concentrations of 89 IMPs in these samples were determined using a multiplexed bead-based microarray protein assay and compared between BD-IPMN and mixed IPMN. …”
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1442
ARHGAP42 promotes cell migration and invasion involving PI3K/Akt signaling pathway in nasopharyngeal carcinoma
Published 2018-08-01“…However, the effect of ARHGAP42 in promoting cell malignancy in nasopharyngeal carcinoma is demonstrated in this study. Microarray and real‐time quantitative PCR were used for a mRNA profiling of ARHGAP42 in nasopharyngeal primary and metastatic carcinoma tissues. …”
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1443
Identifying shared hub genes in LIRI and MASLD through bioinformatics analysis and machine learning
Published 2025-05-01“…Using liver transplantation and MASLD datasets from the Gene Expression Omnibus, we applied Linear Models for Microarray Data and weighted gene co-expression analysis to identify differentially expressed genes and key module genes. …”
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1444
Differential gene expression in patients with anal fistula reveals high levels of prolactin recepetor
Published 2017-01-01“…The aim of the present study was to examine prolactin receptors (PRLR) as inflammatory markers and to correlate their expression with both the complexity of anal fistulas and the likelihood of fistula recurrence. Methods. Microarray was used to screen the differentially expressed gene profile of anal fistula using anal mucosa samples with hemorrhoids with ageand sex-matched patients as controls and then a prospective analysis of 65 patients was conducted with anal fistulas. …”
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1445
Overexpression of KMT9α is associated with poor outcome in cholangiocarcinoma patients
Published 2025-05-01“…For the first time, we investigated the presence of KMT9α in cholangiocarcinoma, the association with histologic subtypes, and its impact on survival. Methods A tissue microarray cohort of all CCA patients who underwent surgical resection with curative intent between 08/2005 and 12/2021 at the University Hospital Frankfurt was immunohistochemically analyzed with the KMT9α antibody. …”
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1446
Comprehensive bioinformatics analysis and experimental verification identify mitochondrial gene Dgat2 as a novel therapeutic biomarker for myocardial ischemia-reperfusion
Published 2025-05-01“…This study aimed to identify potential new targets and biomarkers for mitochondria-related genes in MI/RI.MethodsMI/R microarray data (GSE160516) from the GEO database and a mitochondrial geneset were analyzed. …”
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1447
Reclassification of Variants Following Renal Genetics Testing: Uncommon Yet Impactful for Diagnosis and Management
Published 2024-05-01“…Multigene panel was the most frequently used modality followed by single-gene testing, exome sequencing (ES), chromosomal microarray (CMA), and genome sequencing (GS). At initial report, 52% of patients had ≥1 variants of uncertain significance (VUS) with or without concurrent pathogenic variant(s). …”
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1448
Involvement of WNT Signaling in the Regulation of Gestational Age-Dependent Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation
Published 2017-01-01“…In the present study, we isolated UC-MSCs from 23 infants delivered at 22–40 weeks of gestation and analyzed their gene expression and cell proliferation. Microarray analysis revealed that global gene expression in preterm UC-MSCs was distinct from term UC-MSCs. …”
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1449
The Expression Profile of MicroRNAs in Small and Large Abdominal Aortic Aneurysms
Published 2019-01-01“…Tissue samples of AAA patients and healthy controls were collected, from which miRNA was isolated. Microarray including the complete panel of 2549 miRNAs was used to find expression miRNA profiles that were analysed in three subgroups: small (N = 10) and large (N = 6) aneurysms and healthy controls (N = 5). …”
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1450
Genome-Wide Association Study of Exercise Addiction Among Elite Wrestlers
Published 2025-01-01“…Whole-genome genotyping was performed using DNA microarray. Results: Using a genome-wide approach (<i>p</i> < 1.0 × 10<sup>−</sup>⁵), we identified six suggestively significant single-nucleotide polymorphisms (SNPs) associated with exercise addiction status. …”
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1451
Nanopore-based random genomic sampling for intraoperative molecular diagnosis
Published 2025-01-01“…Results In our retrospective cohort of 26 malignant brain tumors, iSCORED demonstrated 100% concordance in CNV detection, including chromosomal alterations and oncogene amplifications, when compared to clinically validated assays such as Next-Generation Sequencing and Chromosomal Microarray. Furthermore, we validated iSCORED’s real-time applicability in 15 diagnostically challenging primary brain tumors, achieving 100% concordance in detecting aberrant CNV detection, including diagnostic chromosomal gains/losses and oncogene amplifications (10/10). …”
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1452
Genome-wide analysis in the search for candidate genes associated with meat productivity traits in meat-and-dairy goats
Published 2022-12-01“…GWAS analysis using Goat 50K BeadChip high-density DNA microarray determined a genome-wide level of significance for six SNPs located on chromosomes 5, 6, 10 and 16 associated with the live weight of young animals (4 and 8 months old). …”
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1453
Prevalence and Diversity of <i>Staphylococcus aureus</i> in Bulk Tank Milk from Community-Based Alpine Dairy Pastures in Tyrol, Austria
Published 2025-07-01“…Selected isolates representing the different <i>spa</i> types were characterised by DNA microarray-based genotyping, multi-locus sequence typing (MLST), and antimicrobial susceptibility testing. …”
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1454
Establishing an induced pluripotent stem cell bank using urine cells from pediatric patients with neurogenetic diseases
Published 2025-08-01“…The genomic stability of the iPSCs was assessed using chromosomal microarray (CMA). Results UCs were successfully isolated from patients with various early-onset neurogenetic diseases and reprogrammed into iPSCs. …”
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1455
MiR-223-3p regulates erythropoiesis by targeting TGFBR3/Smad signaling pathway in hemoglobin H-Constant Spring disease
Published 2025-12-01“…The present study analyzed miRNAs differential expression profile between patients with HbH-CS disease and healthy subjects by Arraystar Human small RNA Microarray.Methods The differential expression profiles of miRNAs between HbH-CS patients and healthy individuals were analyzed using Arraystar human small RNA microarrays. …”
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1456
Long Noncoding RNA and mRNA m6A Modification Analyses of Periodontal Ligament Stem Cells from the Periodontitis Microenvironment Exposed to Static Mechanical Strain
Published 2022-01-01“…Therefore, we performed an m6A microarray assay with pPLDSCs and hPDLSCs exposed to 12% SMS and found that 143 lncRNAs and 739 mRNAs were differentially methylated. …”
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1457
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway
Published 2025-04-01“…Methods This study utilized TNBC tissue microarrays to detect Peroxiredoxin 2 (PRDX2) expression levels and analyzed the correlation between PRDX2 and tumor invasion as well as invasion-related gene expression through the TCGA database. …”
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1458
Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer
Published 2017-04-01“…Long non-coding RNA microarray was applied to investigate the global long non-coding RNA expression profile in colorectal cancer. …”
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1459
PRMT3 drives PD-L1-mediated immune escape through activating PDHK1-regulated glycolysis in hepatocellular carcinoma
Published 2025-03-01“…Chromatin immunoprecipitation (ChIP) assay demonstrated that PRMT3 promotes lactate-induced PD-L1 expression by enhancing the direct binding of histone H3 lysine 18 lactylation (H3K18la) to the PD-L1 promoter. Tissue microarray analysis showed a positive correlation between PRMT3 and PD-L1 expression in HCC patients. …”
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1460
OTX2 expression contributes progression of gastric cancer in young adults
Published 2025-05-01“…RNA expression profile microarray data of gastric cancer patients ≤ 45 years old and > 45 years old were downloaded from the TCGA database, and differentially expressed genes were screened by Limma package. …”
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