Complex Loci in human and mouse genomes. by Pär G Engström, Harukazu Suzuki, Noriko Ninomiya, Altuna Akalin, Luca Sessa, Giovanni Lavorgna, Alessandro Brozzi, Lucilla Luzi, Sin Lam Tan, Liang Yang, Galih Kunarso, Edwin Lian-Chong Ng, Serge Batalov, Claes Wahlestedt, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Christine Wells, Vladimir B Bajic, Valerio Orlando, James F Reid, Boris Lenhard, Leonard Lipovich

“…Bidirectional promoters were characterized by variable transcriptional start sites and an identifiable midpoint at which overall sequence composition changed strand and the direction of transcriptional initiation switched. In microarray data covering a wide range of mouse tissues, genes in cis-antisense and bidirectionally promoted arrangement showed a higher probability of being coordinately expressed than random pairs of genes. …”
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Polymorphisms in the mitochondrial DNA control region and frailty in older adults. by Ann Z Moore, Mary L Biggs, Amy Matteini, Ashley O'Connor, Sarah McGuire, Brock A Beamer, M Danielle Fallin, Linda P Fried, Jeremy Walston, Aravinda Chakravarti, Dan E Arking

“…At baseline, frailty was identified as the presence of three or more of five indicators (weakness, slowness, shrinking, low physical activity, and exhaustion). mtDNA variation was assessed in a pilot study, including 315 individuals selected as extremes of the frailty phenotype, using an oligonucleotide sequencing microarray based on the Revised Cambridge Reference Sequence. …”
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Prenatal diagnosis of imprinted associated chromosome abnormalities identified by noninvasive prenatal testing (NIPT) by Haishan Peng, Dongmei Wang, Fangfang Guo, Yaping Hou, Tingting Hu, Qianyi Du, Jiexia Yang

“…Abstract To explore the clinical value of noninvasive prenatal testing (NIPT) combined with chromosomal microarray analysis (CMA)/copy number variation sequencing (CNV-seq), methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA), and fluorescence in situ hybridization (FISH) in the early screening of imprinted chromosome abnormalities. …”
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CDC2 mediates progestin initiated endometrial stromal cell proliferation: a PR signaling to gene expression independently of its binding to chromatin. by Griselda Vallejo, Alejandro D La Greca, Inti C Tarifa-Reischle, Ana C Mestre-Citrinovitz, Cecilia Ballaré, Miguel Beato, Patricia Saragüeta

“…Here we identify early downstream targets of cytoplasmic PR signaling and their possible role in endometrial stromal cell proliferation. Microarray analysis of global gene expression changes in UIII cells treated for 45 min with progestin identified 97 up- and 341 down-regulated genes. …”
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Identification of circRNA Expression Profile and Potential Systemic Immune Imbalance Modulation in Premature Rupture of Membranes by Dongni Huang, Yuxin Ran, Ruixin Chen, Jie He, Nanlin Yin, Hongbo Qi

“…In this study, we displayed the expression profiles of circRNAs and mRNAs in plasma and fetal membranes of PROM and normal control (NC) groups based on circRNA microarray, the Gene Expression Omnibus database, and NCBI’s Sequence Read Archive. …”
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Prenatal Diagnosis of a 2.5 Mb De Novo 17q24.1q24.2 Deletion Encompassing KPNA2 and PSMD12 Genes in a Fetus with Craniofacial Dysmorphism, Equinovarus Feet, and Syndactyly by Marie-Emmanuelle Naud, Lucie Tosca, Jelena Martinovic, Julien Saada, Corinne Métay, Loïc Drévillon, Virginie Benoit, Sophie Brisset, Gérard Tachdjian

“…Interstitial 17q24.1 or 17q24.2 deletions were reported after conventional cytogenetic analysis or chromosomal microarray analysis in patients presenting intellectual disability, facial dysmorphism, and/or malformations. …”
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Psicoterapia e neuroscienze: il modello strategico ad orientamento neuroscientifico e il metodo mente - corpo by 1 Mauro Cozzolino, 2 Giovanna Celia

“…In line with these studies, our research team has explored the genomic-molecular basis of our protocol by means of bioinformatic software and DNA microarray. After a single session of Mind-Body Transformations Therapy, we found patterns of experience-dependent gene expression that are associated with stem cell activation, and a reduction of inflammation, cell stress and epigenetic variations. …”
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Genetic Background Modulates lncRNA-Coordinated Tissue Response to Low Dose Ionizing Radiation by Jonathan Tang, Yurong Huang, David H. Nguyen, Sylvain V. Costes, Antoine M. Snijders, Jian-Hua Mao

“…However, the relevance of lncRNAs in the cell and tissue response to ionizing radiation has not yet been characterized. Here we used microarray profiling to determine lncRNA and mRNA expression in mammary glands of BALB/c and SPRET/EiJ mice after low-dose ionizing radiation (LDIR) exposure. …”
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gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection. by Hongxin Li, Huiqing Shang, Dingming Shu, Huanmin Zhang, Jun Ji, Baoli Sun, Hongmei Li, Qingmei Xie

“…We have found a novel tumour-suppressor miRNA, gga-miR-375, associated with avian leukosis tumorigenesis by miRNA microarray in a previous report. We have also previously studied the biological function of gga-miR-375; Overexpression of gga-miR-375 significantly inhibited DF-1 cell proliferation, and significantly reduced the expression of yes-associated protein 1 (YAP1) by repressing the activity of a luciferase reporter carrying the 3'-untranslated region of YAP1. …”
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Novel Detection and Clinical Utility of Serum-Derived Extracellular Vesicle in Angiosarcoma by Kazunori Yokoi, Jing Wang, Yusuke Yoshioka, Yasuhiro Fujisawa, Manabu Fujimoto, Takahiro Ochiya, Atsushi Tanemura

“…The aim of this study is to explore the alteration of serum-derived extracellular vesicle (EV) in angiosarcoma patients and to evaluate its clinical utility as a novel circulating biomarker. In a microarray analysis to examine the differential expression of specific EV-associated microRNAs in sera between cutaneous angiosarcoma patients and healthy controls, 73 microRNAs with significant upregulation and 100 microRNAs with significant downregulation, respectively, were identified in patients with angio-sarcoma. …”
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Characterization of transcriptional changes in ERG rearrangement-positive prostate cancer identifies the regulation of metabolic sensors such as neuropeptide Y. by Petra Massoner, Karl G Kugler, Karin Unterberger, Ruprecht Kuner, Laurin A J Mueller, Maria Fälth, Georg Schäfer, Christof Seifarth, Simone Ecker, Irmgard Verdorfer, Armin Graber, Holger Sültmann, Helmut Klocker

“…We validated our meta-analysis using data from our own independent microarray study (n = 57). 84% and 49% (fold-change>2 and >1.5, respectively) of all transcriptional changes between ERG+ and ERG- prostate cancer determined by meta-analysis were verified in the validation study. …”
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CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis. by Shu Zhang, Zhen Lu, Weiqun Mao, Ahmed A Ahmed, Hailing Yang, Jinhua Zhou, Nicholas Jennings, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Roberto Miranda, Wei Qiao, Veera Baladandayuthapani, Zongfang Li, Anil K Sood, Jinsong Liu, Xiao-Feng Le, Robert C Bast

“…CDK5 protein was measured by immunohistochemical staining of an ovarian cancer tissue microarray to correlate CDK5 expression with overall patient survival. …”
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Deep sleep and parietal cortex gene expression changes are related to cognitive deficits with age. by Heather M Buechel, Jelena Popovic, James L Searcy, Nada M Porter, Olivier Thibault, Eric M Blalock

“…<h4>Conclusions</h4>The F344 rat appears to serve as a reasonable model for some common sleep architecture and cognitive changes seen with age in humans, including the cognitively disrupting influence of active period deep sleep. Microarray analysis suggests that the processes engaged by this sleep are consistent with its function. …”
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mTOR-related linc-PMB promotes mitochondrial biogenesis via stabilizing SIRT1 mRNA through binding to the HuR protein by Chen Qian, Zhang Huaying, Wang Daokun, Liao Wenjing, Liu Yazhou, Cai Yurui, Wang Siyou, Yu Mengqian

“…In this study, we identify an lncRNA named linc-PMB, which is associated with mTOR and promotes mitochondrial biogenesis, through microarray analysis. We demonstrate that the knockdown of linc-PMB results in significantly impaired mitochondrial respiration and biogenesis, along with altered expressions of related genes. …”
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Inflammatory Stimuli Significantly Change the miRNA Profile of Human Adipose-Derived Stem Cells by Zicheng Wang, Haili Li, Li Cheng, Zhongyuan Zhang, Hao Wang, Tongde Lv, Jian Lin, Liqun Zhou

“…A set of cytokines was used to stimulate the hASCs in the cytokine group, while no cytokines were used to stimulate the cells in the normal group. A microarray was used to obtain the miRNA expression profile of hASCs, and RT-PCR was used to validate the miRNAs that were differentially expressed between the two groups. …”
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Overexpression of Testes-Specific Protease 50 (TSP50) Predicts Poor Prognosis in Patients with Gastric Cancer by Fang Liu, Qinghua Cao, Ni Liu, Changzhao Li, Changxuan You, Chuanxin Liu, Ling Xue, Rongcheng Luo

“…Immunohistochemistry (IHC) analysis of TSP50 was performed on a tissue microarray (TMA) containing 334 primary gastric cancers. …”
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Tazarotene-Induced Gene 3 (TIG3) Induces Apoptosis in Melanoma Cells Through the Modulation of Inhibitors of Apoptosis Proteins by Chun-Hua Wang, Lu-Kai Wang, Fu-Ming Tsai

“…<b>Methods:</b> The expression of TIG3 in melanoma tissues was analyzed using a cDNA microarray. Cell viability and cell death were measured using the WST-1 and LDH assay kits, respectively. …”
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Blue light acts as a double-edged sword in regulating sexual development of Hypocrea jecorina (Trichoderma reesei). by Chia-Ling Chen, Hsiao-Che Kuo, Shu-Yu Tung, Paul Wei-Che Hsu, Chih-Li Wang, Christian Seibel, Monika Schmoll, Ruey-Shyang Chen, Ting-Fang Wang

“…Comparative genome-wide microarray analysis demonstrated an overview of light-dependent gene expression versus sexual potency in CBS999.97 (MAT1-2) haploid cells. …”
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Distinct immunological features of oropharyngeal cancer peritumoral tonsillar tissues from inflammatory tonsils and regional lymph nodes: A pilot study. by Naohiro Wakisaka, Makiko Moriyama-Kita, Satoru Kondo, Eiji Kobayashi, Takayoshi Ueno, Yosuke Nakanishi, Kazuhira Endo, Hisashi Sugimoto, Tomokazu Yoshizaki

“…<h4>Methods</h4>RNA samples of PTTs and rLNs from 13 OPCs, and 4 inflammatory tonsils were subjected to microarray analysis, and differentially expressed genes (DEGs) identified from 730 nCounter Panel immune-related genes. …”
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Gene co-expression module study identifies key genes and pathways underpinning hypercholesterolemia-induced atherosclerosis development by Muhammad-Redha Abdullah-Zawawi, Muhammad Irfan Abdul Jalal, Siti Aishah Sulaiman, Nur Alyaa Afifah Md Shahri, Rahman Jamal, Nor Azian Abdul Murad

“…Methods The Affymetrix microarray dataset (GSE13985), which includes samples from five healthy controls and five FH patients, was obtained from the Gene Expression Omnibus (GEO) database. …”
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