Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. by Charles R Farber, Brian J Bennett, Luz Orozco, Wei Zou, Ana Lira, Emrah Kostem, Hyun Min Kang, Nicholas Furlotte, Ani Berberyan, Anatole Ghazalpour, Jaijam Suwanwela, Thomas A Drake, Eleazar Eskin, Q Tian Wang, Steven L Teitelbaum, Aldons J Lusis

“…To begin to unravel the mechanism through which Asxl2 influenced BMD, a gene co-expression network was created using cortical bone gene expression microarray data from the HMDP strains. Asxl2 was identified as a member of a co-expression module enriched for genes involved in the differentiation of myeloid cells. …”
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Identification of sero-reactive antigens for the early diagnosis of Johne's disease in cattle. by Lingling Li, John P Bannantine, Joseph J Campo, Arlo Randall, Yrjo T Grohn, Robab Katani, Megan Schilling, Jessica Radzio-Basu, Vivek Kapur

“…Since serological detection of MAP infected animals during the early stages of infection remains challenging due to the low sensitivity of extant assays, we screened 180 well-characterized serum samples using a whole proteome microarray from Mycobacterium tuberculosis (MTB), a close relative of MAP. …”
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Investigation of potential prognostic biomarkers for colorectal cancer by Hui Li, Jie Liu, WenHui Liu, Liang Zheng, JuHui Chen

“…Material and methods CRC-related microarray datasets were collected from the GEO database and differentially expressed genes (DEGs) were identified. …”
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Differential BACH1 Expression in Basal-like Breast Tumors of Black Women Identified via Immunohistochemistry by N. M. Dowling, Galina Khramtsova, Olufunmilayo Olopade, Shabnam Samankan, Bok-Soon Lee, Jiyoung Lee

“…However, the clinical relevance of BACH1 expression in breast tumors remains poorly understood. Using a tissue microarray from a cohort of 130 patients, we assessed the expression of BACH1 and its known target gene, MCT1 (encoded by <i>SLC16A1</i>), through immunohistochemistry (IHC). …”
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Early-stage immunoexpression of inflammatory, angiogenic, and survival markers in tongue epithelium of mice exposed to hookah smoke. by Aldini Beuting Pereira, Arieli Carini Michels, Sarah Freygang Mendes Pilati, Filipe Modolo, Ana Paula Camargo Martins, Caroline Busatta Vaz De Paula, Seigo Nagashima, Lúcia Noronha, Ana Clara Prado Fonseca, Ariane Jéssica Torres Turmina, Heloisa Franco De Meira, Luisa Gabriela Carneiro Ramos, Thaís Grupp Da Rosa, Thais Maria Dos Santos Eckhardt, Sérgio Aparecido Ignácio, Luciana Reis Azevedo Alanis, Paulo Henrique Couto Souza, Rodrigo Nunes Rached, Bruno Correia Jham, Everdan Carneiro, Emanuela Carla Dos Santos, Aline Cristina Batista Rodrigues Johann

“…Tongues were embedded in paraffin. A tissue microarray was constructed, and immunohistochemistry was performed for Cyclooxygenase 2, NF-kappa B, Vascular Endothelial Growth Factor Receptor 1, and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) for apoptotic analysis. …”
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Different Breeding Values Under Uniform Environmental Condition for Milk Production Yield Traits in Holstein-Friesian Cows by László Bognár, Zsolt Jenő Kőrösi, István Anton, Szabolcs Bene, Ferenc Szabó

“…Genotyping was performed using the EuroGenomics MD v3.0 chipset on the Illumina microarray scanner platform operated by an accredited Illumina laboratory. …”
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Association of lipoprotein(a) and LPA gene with calcific aortic valve disease by Xinyi Yu, Zean Fu, Minghuan Yu, Yibo Shi

“…Meta-analysis was performed using RevMan and Stata. AVC-related gene microarray data were obtained from the GEO database. …”
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Global challenges and solutions to achieving and sustaining measles and rubella elimination by Natasha S. Crowcroft, Anna A. Minta, Sebastien Antoni, Lee Lee Ho, William Perea, Mick N. Mulders, Anindya Sekhar Bose, Aaron Wallace, Diana Chang Blanc, Patrick M. O’Connor

“…Progress will be supported through technological innovations such as microarray patch vaccines. Whether this holistic approach will be more effective than vertical initiatives at achieving measles and rubella elimination remains to be seen. …”
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miR-4780 Derived from N2-Like Neutrophil Exosome Aggravates Epithelial-Mesenchymal Transition and Angiogenesis in Colorectal Cancer by Liang Wang, Yuqiang Shan, Sixin Zheng, Jiangtao Li, Peng Cui

“…Differentially expressed miRNA in neutrophil exosomes have been sequenced by microarray profile, and the effect of N2-like neutrophil-derived exosomal miR-4780 on epithelial-mesenchymal transition (EMT) and angiogenesis was investigated. …”
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Comparison of In Vivo Gene Expression Profiling of RPE/Choroid following Intravitreal Injection of Dexamethasone and Triamcinolone Acetonide by Zeljka Smit-McBride, Elad Moisseiev, Sara P. Modjtahedi, David G. Telander, Leonard M. Hjelmeland, Lawrence S. Morse

“…Differential gene expression of over 34,000 well-characterized mouse genes in the RPE/choroid of 6-week-old C57BL/6J mice was analyzed after intravitreal steroid injections at 1 week and 1 month postinjection, using Affymetrix Mouse Genome 430 2.0 microarrays. The data were analyzed using GeneSpring GX 12.5 and Ingenuity Pathway Analysis (IPA) microarray analysis software for biologically relevant changes. …”
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RETRACTED: EZH2-Mediated microRNA-375 Upregulation Promotes Progression of Breast Cancer via the Inhibition of FOXO1 and the p53 Signaling Pathway by Xin Guan, Aiping Shi, Yabin Zou, Meiyang Sun, Yue Zhan, Yi Dong, Zhimin Fan

“…Differentially expressed genes between tumor and paired normal tissues from BC patients were screened out by microarray analyses. miR-375 was abundantly expressed in BC tissues and cells, and it was correlated with the poor prognosis of patients. …”
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Exploring the immune microenvironment in small bowel adenocarcinoma using digital image analysis. by Fatima Abdullahi Sidi, Victoria Bingham, Stephen McQuaid, Stephanie G Craig, Richard C Turkington, Jacqueline A James, Matthew P Humphries, Manuel Salto-Tellez

“…<h4>Methods</h4>25 patient samples in the form of formalin fixed, paraffin embedded (FFPE) tissue were obtained in tissue microarray (TMAs) format. Automated immunohistochemistry (IHC) staining was performed using validated antibodies for CD3, CD4, CD8, CD68, PD-L1, ICOS, IDO1 and LAG3. …”
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Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules. by Xiaolin Xiao, Aida Moreno-Moral, Maxime Rotival, Leonardo Bottolo, Enrico Petretto

“…We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based) and humans (mRNA-sequencing-based) and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. …”
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Stroma regulates increased epithelial lateral cell adhesion in 3D culture: a role for actin/cadherin dynamics. by Karen F Chambers, Joanna F Pearson, Naveed Aziz, Peter O'Toole, David Garrod, Shona H Lang

“…Stromal signalling did not influence E-cadherin or desmosome RNA or protein expression, but increased E-cadherin/actin co-localisation on the basolateral membranes, and decreased paracellular permeability. Microarray analysis identified several growth factors and pathways that were differentially expressed in stroma in response to 3D epithelial culture. …”
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Integrative bioinformatics analysis and experimental validation of key biomarkers driving the progression of cirrhotic portal hypertension by Meilin Li, Lilin Jiang, Yunrui Ru, Zhonghua Lu, Peng Gu

“…The aim of this study was to identify hub genes for predicting persistent progression of portal hypertension in patients with liver cirrhosis. Methods Related microarray datasets were obtained from the Gene Expression Omnibus database. …”
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Gene Expression Profiling of the Paracrine Effects of Uterine Natural Killer Cells on Human Endometrial Epithelial Cells by Xin Gong, Zhenzhen Chen, Yanxia Liu, Qiudan Lu, Zhe Jin

“…Therefore, we investigated the paracrine effects of the uNK cell-secretion medium on the gene expression profile of endometrial epithelial cells in vitro through microarray analysis. Our results, which were verified by qRT-PCR and western blot, revealed that soluble factors from uNK cells alter the gene expression profiles of epithelial cells. …”
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A rare intrauterine onset growth retardation syndrome caused by mosaic 19p13.3 microduplication: evaluation of GH/IGF- 1 axis and GH therapy response by Emre Özer, Birsen Karaman, Nilay Güneş, Olcay Evliyaoğlu, Beyhan Tüysüz

“…Treatment with GH was started at 4 years and 9 months of age targeting the severe short stature (-3.65 standard deviation score, SDS) since she had significant IGF-1 response to exogenous GH. Microarray study demonstrated a 19p13.3 microduplication of 4.4 Mb. …”
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Involvement of tdTomato-Tagged RPE cells in a mouse PVR model with enzymatically compromised retina by Yao Chen, Xiao Liu, Ashwini Kini, John Y. Liu, Xiaoqin Lu, Ling Gao, Henry J. Kaplan, Douglas C. Dean, Yongqing Liu

“…Gene expression results of the mouse PVR model retinas are consistent with the microarray gene expression profile of human PVR retinas, validating that our mouse PVR model resembles human PVR and is thereby suitable for molecular mechanism and pharmaceutical studies.…”
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Identification and validation of hub gene TNFAIP6 of fibroblast-like synoviocytes in rheumatoid arthritis by LEI Lei, LYU Yuxin, ZHANG Jing

“…Methods‍　‍Four independent synovial tissue microarray transcriptome sequencing datasets and one single cell sequencing dataset were downloaded from the Gene Expression Omnibus (GEO) database, and the hub gene of RA fibroblast-like synovial cells was identified by differential gene analysis, weighted gene co-expression network analysis (WGCNA) and single-cell sequencing data analysis. …”
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ALDOB is a prognostic biomarker and a potential immunotherapy target for clear cell renal cell carcinoma by Wu Xu, Dali Wu, Cuilian Li, Lingfei Yan, Bo Peng, Yang Luo, Dawei Liu, Qing Li, Tao Wang

“…Immunohistochemistry (IHC) was applied to identify the ALDOB level in a tissue microarray. Results The expression of ALDOB demonstrated a strong association with pathologic T stage, pathologic N stage, pathologic M stage, histologic grade, and gender. …”
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