MicroRNA controlled adenovirus mediates anti-cancer efficacy without affecting endogenous microRNA activity. by Ryan Cawood, Suet-Ling Wong, Ying Di, Dilair F Baban, Leonard W Seymour

“…RT-QPCR for mature mir122 in infected livers showed that quantity of mir122 remained unaffected. Genome wide mRNA microarray profiling of infected livers showed that although the transcript level of >3900 different mRNAs changed more than 2-fold following Ad5WT infection, less than 600 were changed by Ad5mir122. …”
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Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. by Chris McDermott-Roe, Marion Leleu, Glenn C Rowe, Oleg Palygin, John D Bukowy, Judy Kuo, Monika Rech, Steffie Hermans-Beijnsberger, Sebastian Schaefer, Eleonora Adami, Esther E Creemers, Matthias Heinig, Blanche Schroen, Zoltan Arany, Enrico Petretto, Aron M Geurts

“…Gene co-expression analysis of a large and heterogeneous compendium of microarray data nominated a sub-population of transcripts that whilst highly correlated with known mitochondrial protein-encoding transcripts (MPETs), are not themselves recognized as generating proteins either localized to the mitochondrion or pertinent to functions therein. …”
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Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis. by Fei Zhu, Pu Wang, Norman H Lee, Mary B Goldring, Konstantinos Konstantopoulos

“…Using significance analysis of microarrays with a 5% false discovery rate, 71 and 60 non-redundant transcripts were identified to be ≥2-fold up-regulated and ≤0.6-fold down-regulated, respectively, in sheared chondrocytes. …”
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circZNF707 promoted glycolysis and tumor progression through miR-668-3p-PFKM axis in NSCLC by Wei Chen, Shuai Fang, Xianqiao Wu, Tianzheng Fang, Ziyuan Chen, Wenmin Su, Yuchao Zhu, Xiaodong Zhao, Chengwei Zhou

“…Abstract Background Circular RNA (circRNA) plays an important regulatory role in the development of human malignancies, but the potential mechanisms of circRNA in non-small cell lung cancer (NSCLC) remain largely unknown. Methods Microarray analysis was used to test for circRNAs differing in expression between NSCLC tumors and healthy adjacent tissues. …”
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A signature of 33 immune‐related gene pairs predicts clinical outcome in hepatocellular carcinoma by Xiao‐Yan Sun, Shi‐Zhe Yu, Hua‐Peng Zhang, Jie Li, Wen‐Zhi Guo, Shui‐Jun Zhang

“…Methods Two RNA‐seq datasets (The Cancer Genome Atlas Program and International Cancer Genome Consortium) and one microarray dataset (GSE14520) were included in this study. …”
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Genome-Wide Characterization and Expression Profiles of the Superoxide Dismutase Gene Family in Gossypium by Jingbo Zhang, Bo Li, Yang Yang, Wenran Hu, Fangyuan Chen, Lixia Xie, Ling Fan

“…Gene structure and protein structure analysis showed that SOD genes have conserved exon/intron arrangement and motif composition. Microarray-based expression analysis revealed that SOD genes have important function in abiotic stress. …”
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Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi. by Aniekanabassi N Udoko, Candice A Johnson, Andrey Dykan, Girish Rachakonda, Fernando Villalta, Sammed N Mandape, Maria F Lima, Siddharth Pratap, Pius N Nde

“…The changes in our selected genes of interest did not all start at the same time point. The transcriptome microarray data, validated by quantitative Real-Time PCR, was also confirmed by immunoblotting and customized Enzyme Linked Immunosorbent Assays (ELISA) array showing significant increases in the protein expression levels of fibrogenic EGR1, SNAI1 and IL 6. …”
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Immunoinflammatory evidence of rheumatoid arthritis caused by COVID-19 by Zhiqiang Shao, Dan Xia, Liang Zhou, Zonghan Xu, Jiaqian Wang

“…Finally, we obtained microarray datasets of COVID-19, RA patients, and normal controls from the GEO database. …”
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Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome by Karol Charkiewicz, Monika Zbucka-Kretowska, Joanna Goscik, Slawomir Wolczynski, Adam Lemancewicz, Piotr Laudanski

“…To assess the expression of autoantibodies in the blood plasma, we used a protein microarray, which allows for simultaneous determination of 9000 proteins per sample. …”
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Development of Type 1 Diabetes Mellitus in Nonobese Diabetic Mice Follows Changes in Thymocyte and Peripheral T Lymphocyte Transcriptional Activity by Thais A. Fornari, Paula B. Donate, Claudia Macedo, Elza T. Sakamoto-Hojo, Eduardo A. Donadi, Geraldo A. Passos

“…The transcriptome of thymocytes and peripheral CD3+ T lymphocytes from prediabetic or diabetic mice analyzed through microarray hybridizations identified 2,771 differentially expressed genes. …”
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Effects of hsa-mir-145-5p on the Regulation of msln Expression in Colorectal Adenocarcinoma by Junhua Li, null Bulin Baila, Tian Xiang Xu, Jiang Song, null Su Rina, Ji Wu, Tegexibaiyin Wang

“…In recent years, research data show that some miRNAs are differentially expressed in cancer tissues, and their expression is closely contributed with the prognosis of CRC. Microarray technology was used, and 179 miRNAs were screened out with significantly altered expression in CRC tissues compared with adjacent tissues. …”
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Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications. by Simon Schafferer, Rimpi Khurana, Violetta Refolo, Serena Venezia, Edith Sturm, Paolo Piatti, Clara Hechenberger, Hubert Hackl, Roman Kessler, Michaela Willi, Ronald Gstir, Anne Krogsdam, Alexandra Lusser, Werner Poewe, Gregor K Wenning, Alexander Hüttenhofer, Nadia Stefanova

“…We investigated the expression patterns of miRNAs and their mRNA targets in substantia nigra (SN) and striatum, two brain regions that undergo neurodegeneration at a later stage in the MSA model, by microarray and RNA-seq analysis, respectively. Analysis was performed at a time point when α-synuclein accumulation was already present in oligodendrocytes at neuropathological examination, but no neuronal loss nor deficits of motor function had yet occurred. …”
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Comparison of effects of p53 null and gain-of-function mutations on salivary tumors in MMTV-Hras transgenic mice. by Dadi Jiang, Catherine I Dumur, H Davis Massey, Viswanathan Ramakrishnan, Mark A Subler, Jolene J Windle

“…Salivary tumors from these mice were characterized with regard to age of tumor onset, tumor growth rates, cell cycle distribution, apoptotic levels, tumor histopathology, as well as response to doxorubicin treatment. Microarray analysis was also performed to profile gene expression. …”
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Promoting Osteogenic Differentiation of Human Adipose-Derived Stem Cells by Altering the Expression of Exosomal miRNA by Shude Yang, Shu Guo, Shuang Tong, Xu Sun

“…Furthermore, in order to investigate the importance of exosomal microRNAs (miRNAs) in osteogenic differentiation of ADSCs, we used microarray assays to analyze the expression profiles of exosomal miRNAs derived from undifferentiated as well as osteogenically differentiated ADSCs; 201 miRNAs were upregulated and 33 miRNAs were downregulated between the two types of exosomes. …”
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Copy Number Variation of Immune-Related Genes and Their Association with Iodine in Adults with Autoimmune Thyroid Diseases by Xing Jin, Yunfeng Guan, Hongmei Shen, Yi Pang, Lixiang Liu, Qingzhen Jia, Fangang Meng, Xiaoye Zhang

“…Blood samples from 15 patients with AITD and 15 controls were assessed by chromosome microarray to identify candidate genes. The copy number of candidate genes and urinary iodine level was determined in adults from areas of different iodine statuses including 158 patients and 181 controls. …”
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Construction of a macrophage-related prognostic signature and assessment of immune checkpoint inhibitor efficacy of HCC by Shouge Zang, Hongwei Chen, Yuqian Han, Di Cui, Jiangtao Yu

“…Functional assays were conducted to assess the effect of PLAUR knockdown on macrophage polarization, tumor cell behavior, and PI3K/AKT/mTOR pathway activity. Tissue microarray immunofluorescence validated PLAUR expression in situ. …”
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PIWI‐interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation by Shan‐Shan Li, Miao Guo, Yao Long, Yuang Cai, Ying Zhao, Shaoyuan Huang, Houzhi Yang, Yonggang Fan, Xu Chen, Xin Jin

“…Here, we identify a novel MIA‐associated brain endothelial piRNA (MIABEPIR) involved in regulating BMEC function and BBB integrity. RNA microarray analysis of foetal brain tissue from MIA‐exposed mice revealed significant changes in piRNA expression, including a marked upregulation of MIABEPIR upregulated piRNAs. …”
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Molecular subtyping combined with multiomics analysis to study correlation between TACE refractoriness and tumor stemness in hepatocellular carcinoma by Qifan He, Yue Xiong, Xiaoyu Yang, Yihui Yu, Zhonghua Chen

“…Methods This research encompassed the analysis of diverse HCC datasets, including RNA-sequencing, microarray, single-cell RNA-sequencing, and clinical cohorts. …”
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Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus. by Sergio P Alpuche-Lazcano, James Saliba, Vivian V Costa, Gabriel H Campolina-Silva, Fernanda M Marim, Lucas S Ribeiro, Volker Blank, Andrew J Mouland, Mauro M Teixeira, Anne Gatignol

“…We next examined the miRNA expression profile in infected primary murine neurons by microarray and found that various miRNAs were dysregulated upon ZIKV infection. …”
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Global systems-level analysis of Hfq and SmpB deletion mutants in Salmonella: implications for virulence and global protein translation. by Charles Ansong, Hyunjin Yoon, Steffen Porwollik, Heather Mottaz-Brewer, Brianne O Petritis, Navdeep Jaitly, Joshua N Adkins, Michael McClelland, Fred Heffron, Richard D Smith

“…From these same samples we also prepared RNA for microarray analysis to determine if alteration of protein expression was mediated post-transcriptionally. …”
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