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961
Prognostic prediction and diagnostic role of Rspondin 1 expression in esophageal squamous cell carcinoma
Published 2025-01-01“…Subsequently, tissue microarray (TMA) and immunohistochemistry (IHC) techniques were employed to assess the protein levels of Rspo1. …”
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962
Expression and function of Connexin 43 and Connexin 37 in the murine zona glomerulosa
Published 2025-02-01“…We found evidence for the expression of murine connexin 43 and 37 using microarray data, in‐situ hybridization and immunohistology. …”
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963
Bioinformatics analysis of potential targets influencing the prognosis of OSCC
Published 2024-06-01“…[Objective:] To apply bioinformatics technology to screen differentially expressed genes (DEGs) in oral squamous cell carcinoma (OSCC) microarray data to further predict potential targets and prognostic genes. …”
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964
FOSB is a key factor in the genetic link between inflammatory bowel disease and acute myocardial infarction: multiple bioinformatics analyses and validation
Published 2025-04-01“…Methods We downloaded IBD and AMI-related microarray datasets from the NCBI Gene Expression Omnibus (GEO) database. …”
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965
MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis
Published 2025-05-01“…Our study aimed to identify and validate hub genes that are differentially expressed in BA, and to investigate their relationship with liver fibrosis.MethodsThe BA microarray datasets GSE46960 and GSE15235 were downloaded from the Gene Expression Omnibus (GEO) database. …”
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966
A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.
Published 2016-09-01“…C. neoformans has multiple virulence mechanisms that are non-host specific, induce damage and interfere with immune clearance. Microarray analysis of C. neoformans strains serially passaged in mice associated a small gene (CNAG_02591) with virulence. …”
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967
Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant ho...
Published 2014-01-01“…Here we present the first microarray study of transcriptional changes induced by the phloem-limited geminivirus TYLCSV infecting tomato, its natural host. …”
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968
Exposing Optimal Feature Sets for Enhancing Machine Learning Performance
Published 2025-01-01“…To evaluate the effectiveness of our approach, we conduct experiments on benchmark microarray datasets from the ADNI database. Comparative analysis is performed against six traditional single objective methods and five other existing multiobjective methods. …”
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969
A novel C2H2 transcription factor that regulates gliA expression interdependently with GliZ in Aspergillus fumigatus.
Published 2014-05-01“…Through protein binding microarray and mutagenesis, we have identified a DNA binding site recognized by GipA that is in extremely close proximity to a potential GliZ DNA binding site in the 5' untranslated region of gliA, which encodes an efflux pump within the gliotoxin cluster. …”
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970
Cytogenomic characterization of mosaic X-ring chromosomes in seventeen patients with Turner syndrome (TS)-42 years of experience at a single-site institution
Published 2025-04-01“…Current guidelines recommend karyotype as the first-line test rather than SNP microarray analysis when aneuploidy is suspected. Conventional cytogenetics is still necessary to understand structural abnormalities, provide genomic context, and detect low-level mosaicism. …”
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971
Transcriptional regulation by CHIP/LDB complexes.
Published 2010-08-01“…Here we use the powerful genetics of Drosophila combined with microarray and bioinformatics analyses to tackle this challenge. …”
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972
Regulation of Myogenesis by MechanomiR-200c/FoxO3 Axis
Published 2025-06-01“…Stretch alters the miRNA expression profile as evidenced by miRNA microarray analysis. We identified miR-200c as one of the highly downregulated mechanosensitive miRNAs (mechanomiRs) whose expression level was increased during differentiation. …”
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973
The enduring hypoxic response of Mycobacterium tuberculosis.
Published 2008-01-01“…These results suggested that additional genes may be essential for entry into and maintenance of bacteriostasis. Detailed microarray analysis of oxygen starved cultures revealed that DosR regulon induction is transient, with induction of nearly half the genes returning to baseline within 24 hours. …”
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974
Site-specific expression of amine oxidases in breast cancer metastases
Published 2018-05-01“…We aimed to evaluate the expression of amine oxidase-related proteins in metastatic breast cancer tissue and determine its clinical implication. A tissue microarray was constructed from a total of 126 metastatic breast tumors (31 bone metastases (24.6%), 36 brain metastases (28.6%), 11 liver metastases (8.7%), and 48 lung metastases (38.1%)). …”
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975
ODSEI Chip: An Open 3D Microfluidic Platform for Studying Tumor Spheroid‐Endothelial Interactions
Published 2025-04-01“…Herein, a novel open 3D‐microarray platform is presented for a spheroid‐endothelium interaction (ODSEI) chip, capable of arraying more than 1000 spheroids on top of the vasculature, compartmentalized for single spheroid‐level analysis of drug resistance, and allows for the extraction of specific spheroids for further analysis. …”
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976
Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.
Published 2010-10-01“…Interestingly, meta-analysis of microarray data in the Geo and Oncomine databases suggests that Zip4 mRNA may also be elevated in many types of cancer. …”
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977
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
Published 2012-07-01“…We measured mRNA and protein levels in manipulated cells by microarray, RT–PCR and western blot analysis, respectively. …”
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978
Epistatic relationships reveal the functional organization of yeast transcription factors
Published 2010-10-01“…Negative genetic interactions, which often identify factors working in non‐essential, redundant pathways, were also enriched for pairs of STFs that co‐regulate similar sets of genes. Microarray analysis demonstrated that pairs of STFs that display negative genetic interactions regulate gene expression in an independent rather than coordinated manner. …”
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979
Identification of key genes and pathways in the following pancreatic ductal adenocarcinoma (PDAC) using integrated bioinformatics analysis
Published 2025-07-01“…This study analyzed microarray datasets (GSE16515, GSE28730, GSE62165, and GSE91035) from the Gene Expression Omnibus to identify differentially expressed genes (DEGs) in PDAC. …”
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980
Fecal carriage of extended spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae after urinary tract infection - A three year prospective cohort study.
Published 2017-01-01“…Isolates without blaCTX-M were investigated for alternative ESBL-determinants with a commercial microarray system. Time to fecal clearance of ESBL producing Enterobacteriaceae was also analysed using Kaplan-Meier estimates. …”
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