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881
Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology
Published 2009-06-01“…We collected protein and mRNA expression data through shot‐gun proteomics and microarray expression analysis of the highly vascular exchange region, microdissected from the human and mouse near‐term placenta. …”
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882
EMP1 as a Potential Biomarker in Liver Fibrosis: A Bioinformatics Analysis
Published 2023-01-01“…In this study, we combined a publicly accessible single-cell transcriptome of human liver with microarray datasets to evaluate the cell-specific expression patterns of differentially expressed genes in the liver. …”
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883
Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease
Published 2025-05-01“…The objective of this study is to investigate the ubiquitination related genes in chronic obstructive pulmonary disease (COPD). Methods The gene microarray dataset from COPD patients and ubiquitination related genes were analyzed. …”
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884
Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Bra...
Published 2016-01-01“…Changes in gene expression (microarray and qPCR) were assessed in the cingulate cortex. …”
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885
Investigation of griffithsin's interactions with human cells confirms its outstanding safety and efficacy profile as a microbicide candidate.
Published 2011-01-01“…In addition, GRFT appears to retain antiviral activity once bound to the surface of PBMC. Finally, RNA microarray studies show that, while CV-N and ConA regulate expression of a multitude of cellular genes, GRFT treatment effects only minimal alterations in the gene expression profile of a human ectocervical cell line. …”
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886
Promising Noninvasive Cellular Phenotype in Prostate Cancer Cells Knockdown of Matrix Metalloproteinase 9
Published 2013-01-01“…Immunostaining of prostate tissue microarray sections illustrated significantly lower levels of CD44v6 in adenocarcinoma than normal tissue. …”
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887
Genetic Analysis of 17q Terminal Partial Trisomy
Published 2024-12-01“…We performed G‐banding karyotype and chromosomal microarray analyses. The child in Family 1 had a 31.3 Mb mosaic duplication on chromosome 17. …”
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888
Cell cycle regulation and cytoskeletal remodelling are critical processes in the nutritional programming of embryonic development.
Published 2011-01-01“…This occurred in the absence of damage to the glomerular ultrastructure. Microarray, proteomic and pathway analyses identified diet-specific and strain-specific gatekeeper genes, proteins and processes which shared a common association with the regulation of the cell cycle, especially the G1/S and G2/M checkpoints, and cytoskeletal remodelling. …”
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889
Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis.
Published 2025-01-01“…<h4>Methods</h4>Ferroptosis-related genes were identified from UC microarray data extracted from the GEO database and FerrDb. …”
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890
Dissection of Ire1 functions reveals stress response mechanisms uniquely evolved in Candida glabrata.
Published 2013-01-01“…C. glabrata Ire1 did not cleave mRNAs encoding Hac1 and other bZIP transcription factors identified in the C. glabrata genome. Microarray analysis revealed that the transcriptional response to ER stress is not mediated by Ire1, but instead is dependent largely on calcineurin signaling and partially on the Slt2 MAPK pathway. …”
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891
iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models.
Published 2013-01-01“…We defined a method to transform microarray data into graph representation that encodes miRNA and gene expression levels and the interactions between them as well. …”
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892
Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks
Published 2011-01-01“…Linear, two-cycle amplification of total RNA, followed by microarray was performed for transcriptome analysis (with qRT-PCR validation). …”
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893
Investigation of Underlying Biological Association and Targets between Rejection of Renal Transplant and Renal Cancer
Published 2023-01-01“…Next-generation sequencing data and corresponding clinical information of patients with clear cell renal cell carcinoma (ccRCC) were obtained from The Cancer Genome Atlas Program (TCGA) database. The microarray data of kidney transplant patients with or without rejection response was obtained from the Gene Expression Omnibus (GEO) database. …”
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894
Identification of a New Lung Cancer Biomarker Signature Using Data Mining and Preliminary In Vitro Validation
Published 2025-06-01“…<b>Methods</b>: Bioinformatics analysis in parallel to data mining analysis was performed on microarray data with lung adenocarcinoma samples to identify potent gene biomarkers associated with lung cancer type. …”
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895
Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
Published 2015-01-01“…Total RNA was isolated and the gene expression profile was determined using DNA microarrays. Comparison of the microarray expression values with qRT-PCR analysis of selected genes validated the results. …”
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896
Improvement in Wrinkles by a Fairy Chemical, 2-Aza-8-oxohypoxanthine
Published 2025-06-01“…2-aza-8-oxohypoxanthine (AOH) has been shown to improve skin barrier function according to DNA microarray studies of normal human epidermal keratinocytes. …”
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897
Unraveling a novel therapeutic facet of Etravirine to confront Hepatocellular Carcinoma via disruption of cell cycle
Published 2025-02-01“…The transcriptomics microarray datasets were explored to retrieve the HCC specific differentially expressed genes, and the significant genes were fed in Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) database to capture the protein-protein interactions, which were visualized in Cytoscape. …”
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898
Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts
Published 2019-01-01“…Finally, analysis of publicly available microarray data sets revealed a potent correlation between high NINJ1 expression and destructive bone disorders in humans. …”
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899
What the VAF? A guide to the interpretation of variant allele fraction, percent mosaicism, and copy number in cancer
Published 2025-07-01“…With the growing use of more technologies including chromosomal microarray, genome sequencing and genome mapping in clinical cytogenetics laboratories, reporting the frequency of SVs and CNVs has increased the complexity of genomic results. …”
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900
Transcriptional profiling of the bladder in urogenital schistosomiasis reveals pathways of inflammatory fibrosis and urothelial compromise.
Published 2012-01-01“…We leveraged our recently developed mouse model of urogenital schistosomiasis to perform the first-ever profiling of the early molecular events that occur in the bladder in response to the introduction of S. haematobium eggs. Microarray analysis of bladders revealed rapid, differential transcription of large numbers of genes, peaking three weeks post-egg administration. …”
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