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801
Transcriptome Classification Reveals Molecular Subgroups in Idiopathic Pulmonary Fibrosis
Published 2022-01-01“…This study aimed to uncover the underlying molecular features for different types of IPF. IPF microarray datasets were retrieved from GEO databases. …”
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802
Gene Expression Profiling of the Optic Nerve Head of Patients with Primary Open-Angle Glaucoma
Published 2017-01-01“…However, genetic studies on POAG from this perspective are limited. Methods. Microarray dataset GSE45570 of the ONH of healthy individuals and POAG patients were downloaded from the Gene Expression Omnibus. …”
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803
General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles
Published 2011-03-01“…Here we present a simple and integrated bioinformatics analysis approach that assembles a public cancer microarray database with a pathway knowledge base for ascertaining and prioritizing upregulated genes encoding cell surface- or membrane-bound proteins, which could serve imaging targets. …”
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804
MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice.
Published 2013-01-01“…Using miRNA target prediction algorithms and the microarray transcriptomic profile of miR-155(-/-) livers, we identified and validated that Nr1h3 (LXRα) as a direct miR-155 target gene that is potentially responsible for the liver phenotype of miR-155(-/-) mice. …”
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805
Identification of novel antiviral host factors by functional gene expression analysis using in vitro HBV infection assay systems.
Published 2025-01-01“…RNA microarray was performed using HBV-infected PXB cells with STAT1 knockdown. …”
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806
Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma
Published 2014-11-01“…Triple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein. According to DNA microarray profiling, breast cancer was divided into several molecular subgroups, including Luminal A and Luminal B; HER2 overexpressing; normal breast- like and basal-like subtype. …”
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807
Inheritance of a Ring Chromosome 21 in a Couple Undergoing In Vitro Fertilization (IVF): A Case Report
Published 2011-01-01“…Parental bloods showed that the mother was mosaic for the ring 21 with a karyotype of 46,XX,r(21)(p11.2q22.3)/46,XX and the father had an unrelated Robertsonian translocation, with a karyotype of 45,XY,rob(13;14)(q10;q10). Microarray analysis of cultured amniocytes determined the extent of the deletion of chromosome 21 material in the ring. …”
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808
Identification of Potential Biomarkers of Septic Shock Based on Pathway and Transcriptome Analyses of Immune-Related Genes
Published 2023-01-01“…GSE57065 and GSE95233 microarray data were used to screen differentially expressed genes (DEGs) in SS. …”
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809
Shannon entropy approach reveals relevant genes in Alzheimer's disease.
Published 2019-01-01“…Since complex diseases are often the result of combinations of gene interactions, microarray data and gene co-expression analysis can provide tools for addressing complexity. …”
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810
Weighted frequent gene co-expression network mining to identify genes involved in genome stability.
Published 2012-01-01“…In this study, we used a network mining algorithm to identify tightly connected gene co-expression networks that are frequently present in microarray datasets from 33 types of cancer which were derived from 16 organs/tissues. …”
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811
Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice.
Published 2008-06-01“…To gain further insight into the molecular basis of the mutant-specific manifestation of age-related phenotypes, we used comparative microarray analysis of young and old female livers to discover gene expression signatures distinguishing Xpd(TTD) mice from their age-matched wild type controls. …”
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812
Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study
Published 2024-01-01“…We explored the expression pattern and clinicopathological significance of ZIC2 in oral cancer through performing in-house tissue microarray and integrated analysis global RNA-seq and microarrays containing large samples. …”
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813
Frieden’s Group-V Aplasia Cutis Congenita with in utero Scarring in a Dichorionic Twin: A Case Report and Comprehensive Literature Review
Published 2024-12-01“…Despite significant dermatological manifestations, the infant showed no other external abnormalities or systemic involvement, and comprehensive screenings, including ultrasounds and chromosomal microarray, were normal. Conclusion: This discussion highlights the rarity of ACC associated with fetus papyraceus, with only a few over 100 cases reported globally. …”
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814
Transcription factor binding site analysis identifies FOXO transcription factors as regulators of the cutaneous wound healing process.
Published 2014-01-01“…The search for significantly overrepresented and co-occurring transcription factor binding sites in the promoter regions of the most differentially expressed genes in microarray data sets could be a powerful approach for finding key regulators of complex biological processes. …”
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815
Large-scale gene expression data clustering through incremental ensemble approach
Published 2024-01-01“…DNA microarray technology monitors gene activity in real-time in living organisms. …”
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816
Have maternal or paternal ages any impact on the prenatal incidence of genomic copy number variants associated with fetal structural anomalies?
Published 2021-01-01“…We conducted a non-paired case-control study (1:2 ratio) among pregnancies undergoing chromosomal microarray analysis (CMA) because of fetal ultrasound anomalies, from December 2012 to May 2020. …”
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817
Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling.
Published 2007-11-01“…Pathway analysis identified other genes regulated by cocaine that code for proteins involved in the remodeling of the cytomatrix and synaptic connections and the inhibition of blood vessel proliferation (PCDH8, LAMB1, ITGB6, CTGF and EphB4). The observed microarray phenotype in the human hippocampus identified RECK and other region-specific genes that may promote long-lasting structural changes with repeated cocaine abuse. …”
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818
A Synopsis of Serum Biomarkers in Cutaneous Melanoma Patients
Published 2012-01-01“…However, the poor sensitivity and specificity of those markers and many other molecules are serious limitations for their routine use in both early (AJCC stage I and II) and advanced stages of melanoma (AJCC stage III and IV). Microarray technology and proteomic research will surely provide new candidates in the near future allowing more accurate definition of the individual prognosis and prediction of the therapeutic outcome and select patients for early adjuvant strategies.…”
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819
Delineation of 2q32q35 Deletion Phenotypes: Two Apparent “Proximal” and “Distal” Syndromes
Published 2013-01-01“…They presented with wide-ranging phenotypic variation including facial dysmorphisms, cleft palate, learning difficulties, behavioural issues and severe heart defects. Microarray analysis confirmed an 8.6 Mb deletion in patients 1 and 2 and a 24.7 Mb deletion in patient 3. …”
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820
Ultradian cortisol pulsatility encodes a distinct, biologically important signal.
Published 2011-01-01“…Comprehensive analysis of the transcriptome response by microarray identified genes with a differential response to pulsatile versus continuous glucocorticoid delivery. …”
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