Searching for biomarkers in the progression from polycystic ovary syndrome to endometrial carcinoma by Zhenzhen Lu, Ying Gao

“…Methods: To identify the hub genes, microarray datasets GSE48301, GSE115810 and GSE3013 were downloaded from Gene Expression Omnibus database. …”
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Constitutional Chromothripsis on Chromosome 2: A Rare Case with Severe Presentation by Afia Hasnain, Laura L. Thompson, Nicole L. Hoppman, Karine Hovanes, Jing Liu, Bita Hashemi

“…We present a case of a female child born with multiple major congenital abnormalities including severe microcephaly, ocular dysgenesis, heart defect, and imperforate anus. Chromosomal microarray and mate pair sequencing identified a complex chromosomal rearrangement involving the terminal end of the long arm of chromosome 2, with two duplications (located at 2p25.3-p25.1 and 2q35-q37.2 regions) and two deletions (located at 2q37.2-q37.3 and 2q37.3 regions) along with structural changes including inverted segments. …”
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Pain-stimulated ultrasound vocalizations and their impact on pain response in mice. by Satoka Kasai, Saki Ukai, Junpei Kuroda, Tsugumi Yamauchi, Daisuke Yamada, Akiyoshi Saitoh, Satoshi Iriyama, Masashi Suzuki, Kazuki Arita, Yoshio Nakano, Satoru Miyazaki, Kazumi Yoshizawa

“…The tactile threshold decreased the next and three days after sound stress exposure in mice. DNA microarray analysis of the mouse thalamus exposed to sound stress revealed increased expression of inflammation-related genes, Prostaglandin-endoperoxide synthase 2 and C-X-C motif chemokine ligand 1. …”
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RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes by Ashish Saini, Jingyu Hou, Wanlei Zhou

“…We propose a novel method to measure and extract the reliable (biologically true or valid) interactions from gene interaction networks and incorporate the extracted reliable gene interactions into our proposed RRHGE algorithm to identify significant gene signatures from microarray gene expression data for classifying ER+ and ER− breast cancer samples. …”
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Herpes simplex virus type-1 infection and spread in a novel porcine corneal explant model is restricted to the epithelium. by Sana Arshad, Hafsa Rana, Naomi R Truong, Ushasree Pattamatta, Kirstie M Bertram, Andrew White, Holly R Chinnery, Nicole A Carnt, Anthony L Cunningham

“…We infected these corneas topically via high-density microarray patches (HD-MAPs) dipped in GFP-labelled HSV-1. …”
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Brain gliomas new transcriptomic discoveries from differentially expressed genes to therapeutic targets by Shiwen Pei, Zhiquan Jiang, Hongwei Cheng

“…This study aimed to identify new genetic targets linked to glioma by analyzing microarray datasets to uncover genetic factors involved in its onset and progression. …”
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Tissue-restricted expression of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles. by Hitomi Nakajima, Yaeko Nakajima-Takagi, Tadayuki Tsujita, Shin-Ichi Akiyama, Takeshi Wakasa, Katsuki Mukaigasa, Hiroshi Kaneko, Yutaka Tamaru, Masayuki Yamamoto, Makoto Kobayashi

“…Seven zebrafish genes (gstp1, mgst3b, prdx1, frrs1c, fthl, gclc and hmox1a) suitable for WISH analysis were selected from candidates for Nrf2 targets identified by microarray analysis. Tissue-restricted induction was observed in the nose, gill, and/or liver for all seven genes in response to Nrf2-activating compounds, diethylmaleate (DEM) and sulforaphane. …”
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A semi-supervised method for predicting transcription factor-gene interactions in Escherichia coli. by Jason Ernst, Qasim K Beg, Krin A Kay, Gábor Balázsi, Zoltán N Oltvai, Ziv Bar-Joseph

“…To further demonstrate the utility of our inferred interactions, we generated a new microarray gene expression dataset for the aerobic to anaerobic shift response in E. coli. …”
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Lack of effect of the Salmonella deubiquitinase SseL on the NF-κB pathway. by Francisco S Mesquita, David W Holden, Nathalie Rolhion

“…To attempt to clarify these discrepancies, we compared mRNA levels in mouse primary bone marrow-derived macrophages infected with wild-type or sseL mutant strains using a genome-wide microarray. There was no detectable effect of loss of SseL on mRNA levels corresponding to any known NF-κB-regulated gene. …”
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A retrospective analysis of prenatal genetic results in fetal hydronephrosis. by Keqin Jin, Xiayuan Xu, Yue Qian, Liping Zhang, Min Hu, Jianfeng Luo

“…<h4>Objective</h4>To discuss the application value of technologies such as chromosome microarray analysis (CMA) in fetuses with hydronephrosis and pyelectasis.…”
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The liver pharmacological and xenobiotic gene response repertoire by Georges Natsoulis, Cecelia I Pearson, Jeremy Gollub, Barrett P Eynon, Joe Ferng, Ramesh Nair, Radha Idury, May D Lee, Mark R Fielden, Richard J Brennan, Alan H Roter, Kurt Jarnagin

“…Abstract We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound‐treated rats. …”
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CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex. by Eimear E Holohan, Camilla Kwong, Boris Adryan, Marek Bartkuhn, Martin Herold, Rainer Renkawitz, Steven Russell, Robert White

“…We carried out chromatin immunopurification coupled with genomic microarray analysis to identify CTCF binding sites within representative regions of the Drosophila genome, including the 3-Mb Adh region, the BX-C, and the Antennapedia complex. …”
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Atm inhibition decreases lens opacity in a rat model of galactose-induced cataract. by Masaya Nagaya, Fumito Kanada, Masaru Takashima, Yoshihiro Takamura, Masaru Inatani, Masaya Oki

“…Subsequently, we used microarray analysis to investigate the underlying molecular mechanisms of action, and extracted genes that were upregulated by galactose-induced opacity, but not by inhibitor treatment. …”
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Bioinformatics-Driven Investigations of Signature Biomarkers for Triple-Negative Breast Cancer by Shristi Handa, Sanjeev Puri, Mary Chatterjee, Veena Puri

“…The basic premise of this study was to investigate key signature genes and signaling pathways involved in triple-negative breast cancer using bioinformatics approach. Microarray data set GSE65194 from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus was used for identification of differentially expressed genes (DEGs) using R software. …”
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P67 | EMERGING ROLE OF NUCLEAR PHOSPHOLIPASE C BETA 1 AS POTENTIAL BIOMARKER IN LUNG CANCER

“…PLCβ1 displayed favorable results, therefore its expression was evaluated through immunohistochemistry on a commercial tissue microarray. Notably, the array revealed a consistent nuclear overexpression of the enzyme in tumoral tissue of patients. …”
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Sensitive and precise quantification of insulin-like mRNA expression in Caenorhabditis elegans. by L Ryan Baugh, Nicole Kurhanewicz, Paul W Sternberg

“…We validated the platform using 53 RNA samples previously characterized by high density oligonucleotide microarray analysis. For this set of genes and the standard nCounter protocol, sensitivity and precision were comparable between the two platforms. …”
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Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients. by Meredith G Banigan, Patricia F Kao, James A Kozubek, Ashley R Winslow, Juan Medina, Joan Costa, Andrea Schmitt, Anja Schneider, Howard Cabral, Ozge Cagsal-Getkin, Charles R Vanderburg, Ivana Delalle

“…Multiple statistical analyses of microarray data suggested that certain exosomal miRNAs were differentially expressed in SZ and BD subjects in comparison to controls. …”
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Ocifisertib alleviates the gasdermin D-independent pyroptosis of nucleus pulposus cells by targeting GSDME by Yu Lin, Qiyong Chen, Shaoqiang Liu, Boling Liu

“…Abstract This study aimed to elucidate the cellular and molecular mechanisms of GSDME in GSDMD independent nucleus pulposus (NP) cell pyroptosis. We analyzed microarray datasets to identify differentially expressed genes (DEGs) in the progression of intervertebral disc degeneration (IDD) and conducted Gene Ontology analysis to elucidate DEGs-participated biological processes. …”
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Infection of Human Coronary Artery Endothelial Cells by Group B Streptococcus Contributes to Dysregulation of Apoptosis, Hemostasis, and Innate Immune Responses by Claudia Beyrich, Jürgen Löffler, Anna Kobsar, Christian P. Speer, Susanne Kneitz, Martin Eigenthaler

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The antioxidant stress effect of granulin precursor in vitiligo by Haoran Guo, Jing Chen, Ling Jiang

“…Hence, leveraging single—cell sequencing and microarray data, we investigated the role of cell—cell and ligand receptor interactions in the pathogenesis of vitiligo. …”
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