ADP-ribosylation factor 6 expression increase in oesophageal adenocarcinoma suggests a potential biomarker role for it. by Venkateswarlu Kanamarlapudi, Salman Tamaddon-Jahromi, Kate Murphy

“…We further evaluated ARF6 protein expression in oesophageal adenocarcinoma (EAC) tissue microarray cores by immunohistochemistry. The ARF6 gene expression levels are highly variable between healthy and cancer tissues. …”
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Quantitative assessment of factors affecting the sensitivity of a competitive immunomicroarray for pesticide detection by Erik Belleville, Martin Dufva, Jens Aamand, Leif Bruun, Claus B.V. Christensen

“…Analytical protein microarrays offering highly parallel analysis can become an invaluable tool for a wide range of immunodiagnostic applications. …”
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Role of Genetic and Epigenetic Factors and Mechanisms Involved in the Occurrence of Congenital Heart Diseases (CHD) by Fateme Tabrizi, Mehri Khatami, Mohammad Mehdi Heidari

“…Advanced research in molecular genetics, especially techniques such as whole-exome sequencing and chromosomal microarray analysis, which focus on protein-coding regions of the human genome, has identified hundreds of genes associated with the development of CHD. …”
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Rapid changes in transcription profiles of the Plasmodium yoelii yir multigene family in clonal populations: lack of epigenetic memory? by Deirdre Cunningham, Jannik Fonager, William Jarra, Celine Carret, Peter Preiser, Jean Langhorne

“…Individual parasites of the rodent malaria Plasmodium yoelii, selected by micromanipulation, transcribe only 1 to 3 different pir (yir) suggesting tight transcriptional control at the level of individual cells. Using microarray and quantitative RT-PCR, we show that despite this very restricted transcription in a single cell, many yir genes are transcribed throughout the intra-erythrocytic asexual cycle. …”
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An efficient leukemia prediction method using machine learning and deep learning with selected features. by Mahwish Ilyas, Muhammad Ramzan, Mohamed Deriche, Khalid Mahmood, Anam Naz

“…The suggested work predicts and classifies leukemia subtypes in gene data CuMiDa (GSE9476) using feature selection and ML techniques. The Curated Microarray Database (CuMiDa) collected 64 samples representing five classes of leukemia genes out of 22283 genes. …”
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Metabolomic and flux‐balance analysis of age‐related decline of hypoxia tolerance in Drosophila muscle tissue by Laurence Coquin, Jacob D Feala, Andrew D McCulloch, Giovanni Paternostro

“…We expand the reactions in the model using tissue‐ and age‐specific microarray data from the literature, and then examine metabolomic profiles of thoraxes after 4 h at 0.5% O2 and after 5 min of recovery in 40‐ versus 3‐day‐old flies. …”
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Exploring the Functional Disorder and Corresponding Key Transcription Factors in Intraductal Papillary Mucinous Neoplasms Progression by Guiying Bai, Chenxuan Wu, Yingtang Gao, Guiming Shu

“…This study has analyzed the gene expression patterns of an IPMN microarray dataset including normal pancreatic ductal tissue (NT), intraductal papillary mucinous adenoma (IPMA), intraductal papillary mucinous carcinoma (IPMC), and invasive ductal carcinoma (IDC) samples. …”
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Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma by Rui Liu, Haiyang Zhang, Yan Zhang, Shuang Li, Xinyi Wang, Xia Wang, Cheng Wang, Bin Liu, Ke Zen, Chen-yu Zhang, Chunni Zhang, Yi Ba

“…In addition, the expression levels of 21,400 genes in tissues and cells were detected by microarray. It was shown that peroxisome proliferator-activated receptor gamma coactivator-1 alpha expression was significantly downregulated in hepatocellular carcinoma compared with normal liver tissues. …”
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CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway by Liubing Hou, Liubing Hou, Zengyao Hao, Ge Zhang, Jiayuan Li, Yu Wang, Xiaoying Xue, Xiaoying Xue, Huandi Zhou, Huandi Zhou, Huandi Zhou

“…This study aims to systematically elucidate the molecular mechanisms by which CD9 regulates malignant phenotypes and radiosensitivity through the AKT/GSK3β signaling pathway in ESCC.MethodsTCGA data, ESCC tissues microarray, in vitro experiments, and patient cohorts were utilized to investigate the expression patterns, functional mechanisms, and clinical relevance of CD9 in ESCC. …”
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Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. by Joseph Landry, Alexei A Sharov, Yulan Piao, Lioudmila V Sharova, Hua Xiao, Eileen Southon, Jennifer Matta, Lino Tessarollo, Ying E Zhang, Minoru S H Ko, Michael R Kuehn, Terry P Yamaguchi, Carl Wu

“…Histological analyses of lineage markers show that Bptf(-/-) embryos implant but fail to establish a functional distal visceral endoderm. Microarray analysis at early stages of differentiation has identified Bptf-dependent gene targets including homeobox transcriptions factors and genes essential for the development of ectoderm, mesoderm, and both definitive and visceral endoderm. …”
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Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early development. by Lisa Shaw, Sharon F Sneddon, Leo Zeef, Susan J Kimber, Daniel R Brison

“…We have therefore investigated global gene expression profiles using polyAPCR amplification and microarray technology applied to individual human oocytes and 4-cell and blastocyst stage embryos. …”
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Acute Changes in Rat Tissue Gene Expression Following Exposure to Flight Relevant Hypobaria by Apurva Borcar, Flaubert Tchantchou, Amol C. Shetty, Anup Mahurkar, Gary Fiskum

“…At the end of the exposures, RNA was isolated from lung, blood, heart, and brain (hippocampus), levels of gene expression were measured via microarray analysis, and canonical pathway analysis identified the primary gene pathways enriched by the exposures. …”
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Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. by Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P van der Brug, Jonathan A Cooper, Mark R Cookson, John A Hardy, Brian W Howell

“…Genomic regions that regulate the phospho Tau phenotype in dab1 mutants have previously been identified. Using a microarray gene expression comparison between dab1-mutants from the high-phospho Tau expressing and low-phospho Tau expressing strains, we identified Stk25 as a differentially expressed modifier of dab1-mutant phenotypes. …”
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Synchrotron Radiation-Induced X-Ray Emission to Identify Metal Ions in Preparations of Purified Protein by Thomas Pfister, Huan Feng, Eckard Wimmer, Keith W. Jones

“…Thus, SRIXE may have wide use as a particularly effective method for rapidly determining trace metals in microarray samples.…”
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The Differential Gene Expression Pattern of Mycobacterium tuberculosis in Response to Capreomycin and PA-824 versus First-Line TB Drugs Reveals Stress- and PE/PPE-Related Drug Targ... by Li M. Fu, Shu C. Tai

“…In this study, we performed a new bioinformatics analysis on microarray-based gene expression data obtained from the public domain to explore genes that were differentially induced by drugs between the group of capreomycin and PA-824 and the group of mainly the first-line TB drugs. …”
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Recombination and population structure in Salmonella enterica. by Xavier Didelot, Rory Bowden, Teresa Street, Tanya Golubchik, Chris Spencer, Gil McVean, Vartul Sangal, Muna F Anjum, Mark Achtman, Daniel Falush, Peter Donnelly

“…We sequenced around 10% of the core genome of 114 isolates of enterica using a resequencing microarray. Application of two different analysis methods (Structure and ClonalFrame) to our genomic data allowed us to define five clear lineages within S. enterica subspecies enterica, one of which is five times older than the other four and two thirds of the age of the whole subspecies. …”
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Insights into the involvement of noncoding RNAs in 5-fluorouracil drug resistance by Jun Deng, Yi Wang, Jun Lei, Wan Lei, Jian Ping Xiong

“…Despite advancements in bioresearch technologies in the past several decades, the molecular mechanisms of 5-fluorouracil resistance have not been completely clarified. Recently, microarray analyses have shown that noncoding RNAs (i.e. microRNAs and long noncoding RNAs) play a vital role in 5-fluorouracil resistance in multiple cancer cell lines. …”
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Genomic Profiling of a Human Leukemic Monocytic Cell-Line (THP-1) Exposed to Alpha Particle Radiation by Vinita Chauhan, Matthew Howland

“…Twenty-four hours and three days after exposure gene expression was monitored using microarray technology. A total of 16 genes were dose responsive and classified as early onset due to their expression 24 h after exposure. …”
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Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons. by Iain T Strickland, Louise Richards, Fiona E Holmes, David Wynick, James B Uney, Liang-Fong Wong

“…Following injury, dorsal root ganglion (DRG) neurons undergo transcriptional changes so as to adopt phenotypic changes that promote cell survival and axonal regeneration. Here we used a microarray approach to profile changes in a population of small noncoding RNAs known as microRNAs (miRNAs) in the L4 and L5 DRG following sciatic nerve transection. …”
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Advances in Research on Isothermal Signal Amplification Mediated MicroRNA Detection of Clinical Samples: Application to Disease Diagnosis by Yu Han, Xin Sun, Sheng Cai

“…However, the intrinsic characteristics of miRNAs, including their low abundance, short sequence lengths, and high family-specific sequence homology, render traditional detection methods such as Northern blot hybridization, microarray use, and reverse transcription quantitative PCR (RT-qPCR) inadequate for meeting the stringent requirements of clinical detection in biological samples, a task requiring accuracy, rapidity, high detection power, specificity, and cost-effectiveness. …”
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