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641
Optical genome mapping for detection of chromosomal aberrations in prenatal diagnosis
Published 2023-08-01“…Compared with the widely used chromosomal microarray analysis, optical genome mapping additionally determined the relative orientation and position of repetitive segments for seven cases with duplications or triplications. …”
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642
Subgroup analysis of imaging scans, invasive examinations and prognosis in mild-to-moderate isolated foetal cerebral ventriculomegaly: a retrospective study in China
Published 2024-12-01“…The results of foetal chromosomal microarray analysis, virological tests of umbilical cord blood or amniotic fluid, foetal magnetic resonance imaging and ultrasound were collected. …”
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643
Using Aptamers for Cancer Biomarker Discovery
Published 2013-01-01“…Aptamers can be paired with recent advances in nanotechnology, microarray, microfluidics, and other technologies for applications in clinical medicine. …”
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644
Exploring the diversity of Arcobacter butzleri from cattle in the UK using MLST and whole genome sequencing.
Published 2013-01-01“…The completion of an A. butzleri genome sequence along with microarray analysis of 13 isolates in 2007 revealed a surprising amount of diversity amongst A. butzleri isolates from humans, animals and food. …”
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645
Identification of a Novel 15q21.1 Microdeletion in a Family with Marfan Syndrome
Published 2022-01-01“…After whole exome sequencing (WES) and chromosomal microarray analysis (CMA) in these individuals, bioinformatics and inheritance analyses were performed. …”
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646
Asymptomatic Right Ventricular Hypoplasia in Twin Siblings: A Normal Variant or Cause of Early Mortality?
Published 2019-01-01“…However, the chromosome microarray analysis of the twins did not identify any variations of clinical significance.…”
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647
Proteomic associations with cognitive variability as measured by the Wisconsin Card Sorting Test in a healthy Thai population: A machine learning approach.
Published 2025-01-01“…Differentially expressed proteins (DEPs) were identified using label-free proteomics and analyzed with the Linear Model for Microarray Data. We discovered 213 DEPs between lower and higher cognition groups, with 155 upregulated in the lower cognition group and enriched in the IL-17 signaling pathway. …”
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648
Creation of a minimal tiling path of genomic clones for Drosophila: provision of a common resource
Published 2004-08-01“…In total, the 25,135 clones represent 76.7 Mb—equivalent to about 67% of the genome —and would be suitable for producing a microarray on a single slide.…”
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649
An enhanced single base extension technique for the analysis of complex viral populations.
Published 2009-10-01“…This single base extension (SBE) based microarray platform was designed and optimized using poliovirus as the target genotype, but can be easily adapted to assay populations derived from any organism. …”
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650
In Silico Analysis of Arabidopsis thaliana Peroxisomal 6-Phosphogluconate Dehydrogenase
Published 2016-01-01“…The data show that a group of plant 6PGDHs contains an archetypal type 1 peroxisomal targeting signal (PTS), while in silico gene expression analysis using affymetrix microarray data suggests that Arabidopsis p6PGDH appears to be mainly involved in xenobiotic response, growth, and developmental processes.…”
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651
Alterations of circulating exosomal microRNAs in an LPS‐induced depression model of male mice: Potential role in the anti‐depressive effects of acupuncture
Published 2025-04-01“…Using an LPS‐induced depression model, we examined acupuncture's effects on depression‐like behaviors and circulating exosomal miRNAs in serum. Microarray data revealed multiple miRNAs significantly altered by LPS or acupuncture, and subsequent bioinformatics analyses (TargetScan, KEGG, and Gene Ontology) identified pathways related to neuroinflammation, synaptic signaling, and circadian regulation. …”
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652
Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data.
Published 2010-08-01“…We also present NetWalk analysis of microarray gene expression data from MCF7 cells exposed to different doses of doxorubicin, which reveals a switch-like pattern in the p53 regulated network in cell cycle arrest and apoptosis. …”
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653
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.
Published 2016-01-01“…These data suggest that serglycin proteoglycans play a role in extravasation as well as colonization and growth of metastatic cells. A microarray expression analysis and functional annotation of differentially expressed genes identified several biological pathways where serglycin may be important. …”
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654
High-Resolution Genomic Profiling of Chromosomal Abnormalities in Human Stem Cells Using the 135 K StemArray
Published 2012-01-01“…Here, we describe an improved version of our StemArray, a stem-cell-focused comparative genomic hybridization (aCGH) microarray, which contains 135,000 probes and covers over 270 stem cell and cancer related genes at the exon level. …”
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655
HIF-1 inhibition reverses opacity in a rat model of galactose-induced cataract.
Published 2024-01-01“…We found that treatment with the HIF-1 inhibitors 2-Methoxyestradiol (2ME2), YC-1, and Bavachinin decreased lens opacity. Microarray analysis on 2ME2-treated samples, in which opacity was decreased, identified genes upregulated by galactose and downregulated by inhibitor treatment. …”
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656
Screening and bioinformatics analysis of IgA nephropathy gene based upon GEO database
Published 2021-01-01“…Objective To identify novel biomarkers of IgA nephropathy(IgAN)through bioinformatics analysis and elucidate the possible molecular mechanism of IgAN.Methods The microarray datasets of GSE104948,GSE93798 and GSE37460 containing IgAN patients and healthy controls were downloaded from the GEO database and analyzed by using the limma R package for obtaining differentially expressed genes.Then GO and KEGG pathway enrichment analyses were performed.And STRING and Cytoscape software were utilized for constructing protein interaction networks for elucidating the molecular mechanism of IgAN.Results Thirty DEGs were identified, including 16 up-regulated genes and 14 down-regulated genes.Up-regulated genes such as FN1 and COL1 A2 are mainly involved in extracellular matrix receptor interaction and PI3 K-Akt signaling pathway.ALB gene was significantly down-regulated in IgA nephropathy.And FN1,COL1 A2,ALB and FABP genes were screened as hub genes.Conclusion FN1,COL1 A2,ALB and FABP genes may play an important role in the development of IgA nephropathy and serve as potential molecular targets for diagnosing and treating IgAN.…”
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657
Glucose regulates transcription in yeast through a network of signaling pathways
Published 2009-02-01“…Abstract Addition of glucose to yeast cells increases their growth rate and results in a massive restructuring of their transcriptional output. We have used microarray analysis in conjunction with conditional mutations to obtain a systems view of the signaling network responsible for glucose‐induced transcriptional changes. …”
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658
Integration of the transcriptome and glycome for identification of glycan cell signatures.
Published 2013-01-01“…The model further elucidated limitations in the two analytical platforms including a defect in the microarray for detecting the GnTV (MGAT5) enzyme. Our results demonstrate the potential of systems glycobiology tools for elucidating key glycan biomarkers and potential therapeutic targets. …”
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659
Determination of Viral Nucleic Acid in the Human Blood
Published 2018-12-01“…Methods such as in situ hybridization, reverse transcription reaction (RT-PCR), nested PCR, multiplex PCR, as well as DNA microarray technology, and the method of massive parallel sequencing are considered in detail. …”
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660
Discovering structural cis‐regulatory elements by modeling the behaviors of mRNAs
Published 2009-04-01“…We applied our structural cis‐regulatory element detector (StructRED) to microarray and mRNA sequence data from Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens. …”
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