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481
Clinical features and genetic analysis of a family with t(5;9) (p15;p24) balanced translocation leading to Cri-du-chat syndrome in offspring
Published 2025-05-01“…We also used chromosomal microarray analyses (CMA) to detect copy number variants. …”
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482
Probing the molecular mechanism of kaempferol in relieving rheumatoid arthritis based on network pharmacology
Published 2025-04-01“…Target gene validation was conducted through microarray analysis. Molecular docking was employed to evaluate the relationship between kaempferol and various key targets. …”
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483
Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.
Published 2015-01-01“…The intestinal transcriptome was also analyzed using a gene microarray approach. When the area containing tumors was compared with the entire colonic area of each mouse, the tumor burden was decreased in AOM/DSS-treated TSP-1-/- versus wild type (WT) mice. …”
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484
Prenatal Diagnosis of WAGR Syndrome
Published 2015-01-01“…The key point for this rare diagnosis was the decision to perform chromosomal microarray analysis after antenatal diagnosis of absent corpus callosum and absent cavum septum pellucidum, as this finding mandates search for potentially associated genetic disorders. …”
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485
Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.
Published 2014-01-01“…To gain understanding of the host responses at cellular level, a microarray analysis was performed using primary rhesus macaque AMs infected with either Ames or Sterne spores. …”
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486
Identification and functional analysis of light-responsive unique genes and gene family members in rice.
Published 2008-08-01“…Using a rice NSF45K oligo-microarray to compare 2-week-old light- and dark-grown rice leaf tissue, we identified 365 genes that showed significant 8-fold or greater induction in the light relative to dark conditions. …”
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487
Prediction of the number of activated genes in multiple independent Cd(+2)- and As(+3)-induced malignant transformations of human urothelial cells (UROtsa).
Published 2014-01-01“…Using a pilot study with small sample size, this method also helps microarray experimental design by determining the number of samples required to identify the common activated gene set.…”
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488
The Comparison of Three Measures in Feature Selection
Published 2018-02-01“…By combining them with the fast correlation-based filter ( FCBF) feature selection method,we make the comparison of selected feature subset from 8 gene microarray and image datasets. Experimental results indicate that the feature subsets selected by linear correlation coefficient based FCBF obtain better classification accuracy in gene microarray datasets than in image datasets,while mutual information and symmetrical uncertainty based FCBF tend to obtain better results in image datasets. …”
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489
Regulation of neutrophil senescence by microRNAs.
Published 2011-01-01“…Total RNA from highly purified neutrophils was prepared and subjected to microarray analysis using the Agilent human miRNA microarray V3. …”
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490
Meta-analysis of pathway enrichment: combining independent and dependent omics data sets.
Published 2014-01-01“…The framework is evaluated and applied in the joint analysis of Metabolomics mass spectrometry and Transcriptomics DNA microarray data in the context of plant wounding. In extensive studies of simulated data set dependence, the introduced correlation could be fully reconstructed by means of the covariance estimation based on pathway enrichment. …”
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491
p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.
Published 2006-11-01“…However, genome-wide microarray analysis indicated that there was essentially no overlap between genes positively regulated by PMK-1 and DAF-16, suggesting that they form parallel pathways to promote immunity. …”
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492
Identification of Gene Modules Associated with Low Temperatures Response in Bambara Groundnut by Network-Based Analysis.
Published 2016-01-01“…Therefore, in this study we developed a computational pipeline to identify and analyze the genes and gene modules associated with low temperature stress responses in bambara groundnut using the cross-species microarray technique (as bambara groundnut has no microarray chip) coupled with network-based analysis. …”
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493
Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion.
Published 2015-01-01“…CSTA is deregulated in several skin cancers, including squamous cell carcinomas (SCC) and loss of function mutations lead to recessive skin fragility disorders. The microarray results were confirmed by qPCR, immunoblotting, and immunohistochemistry. …”
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494
Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay
Published 2018-01-01“…Furthermore, Western blotting and RT-qPCR were used to validate the results of microarray and iTRAQ. In conclusion, Cyp7a1, Cp, and RT1-EC2 are differentially expressed genes/proteins since they showed a similar trend in rats in the model group and the pioglitazone-treated group.…”
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495
Analysis of cataract-regulated genes using chemical DNA damage induction in a rat ex vivo model.
Published 2022-01-01“…Microarray findings in MMS-induced opacity were validated and gene expression was measured from Days 1-4 using RT-qPCR. …”
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496
Molecular characterization of adipose tissue in the African elephant (Loxodonta africana).
Published 2014-01-01“…RNA was extracted and histological sections created and analyzed by microarray, PCR and immunohistochemistry respectively. …”
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497
Gene Expression by PBMC in Primary Sclerosing Cholangitis: Evidence for Dysregulation of Immune Mediated Genes
Published 2006-01-01“…The precise role of the immune system in the pathogenesis of PSC remains unknown. We used RNA microarray analysis to identify immune-related genes and pathways that are differentially expressed in PSC. …”
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498
Identification of G1-regulated genes in normally cycling human cells.
Published 2008-01-01“…To verify synchrony of the cell populations under study, we utilized methods including BrdU uptake, FACS, and microarray analyses of histone gene activity. We also examined stress response gene activity. …”
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499
AssayBLAST: A Bioinformatic Tool for <i>In Silico</i> Analysis of Molecular Multiparameter Assays
Published 2025-04-01“…Accurate primer and probe design is essential for molecular applications, including PCR, qPCR, and molecular multiparameter assays like microarrays. The novel software tool AssayBLAST addresses this need by simulating interactions between oligonucleotides and target sequences. …”
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500
Transcriptome Profiling of IL-17A Preactivated Mesenchymal Stem Cells: A Comparative Study to Unmodified and IFN-γ Modified Mesenchymal Stem Cells
Published 2017-01-01“…Microarray analyses identified 1278 differentially regulated genes between MSC-γ and UT-MSC and 67 genes between MSC-17 and UT-MSC. …”
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