Total neoadjuvant chemotherapy according to the FOLFIRINOX regimen for locally advanced adenocarcinoma of the stomach and cardioesophageal junction: interim results by M. V. Sedova, M. A. Batov, A. A. Kolomeytseva, V. M. Khomyakov, N. N. Volchenko, A. A. Fedenko

“…Patients with histologically confirmed locally advanced gastric adenocarcinoma and CEJ, clinical stage cT3 or higher and/or regional lymph node involvement (cN+), without evidence of distant metastasis were included in our open-label, single-centre, non-randomised study. …”
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Real world study on combining local interventions with systemic therapy in unresectable hepatocellular carcinoma by Zhaosong Xue, Ming Yao, Kang Chen, Taiyun Huang, Jianjun Li, Jian Chen, Fei Huang, Yubin Huang, Xiaoyong Cai, Yihe Yan

“…Other independent risk factors related to overall survival contained extrahepatic metastasis (HR, 2.152; 95% CI, 1.076–4.302; P = 0.030), tumor number ≥ 4 (HR, 2.058; 95% CI, 1.001–4.234; P = 0.049) and radiological remission (HR, 0.233; 95% CI, 0.071–0.768; P = 0.017). …”
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Research on therapeutic clinical trials including immunotherapy in triple-negative breast cancer: a bibliometric analysis by Qi Xu, Xiaoyu Feng, Siyuan Qin, Yu Hong, Rui Cui, Jia Liang, Zhuya Xiao, Yuan Li

“…BackgroundBreast cancer, particularly triple-negative (TNBC), is a leading malignancy with aggressive traits and high metastasis rates. Clinical trial is an important tool for optimizing therapeutic strategies in the evaluation of the safety and efficacy for TNBC. …”
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Phosphatidylinositol promoted the proliferation and invasion of pituitary adenoma cells by regulating POU1F1 expression by Tongjiang Xu, Xiaodong Zhai, RuiWei Wang, Xiaoben Wu, ZhiZhen Zhou, MiaoMiao Shang, Chongcheng Wang, Tengfei Qi, Wei Yang

“…In addition, PI propelled the metastasis of GH3 cells in vivo, and elevated the expression of PITPNM1, POU1F1, C2orf15 and LDHA. …”
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Clinicopathological characteristics and survival outcomes of women aged ≤45 and >45 years with endometrial adenocarcinoma in tertiary referral hospital: a 21-year cohort study by Tarinee Manchana, Pinyada Panyavaranant, Juthamas Rattanachaipipat

“…Independent prognostic factors consist of non-endometrioid histology, involvement of the lower uterine segment and cervix, omental metastasis, lymphovascular invasion and advanced stage.Conclusions Young patients with endometrial cancer exhibit distinct favourable clinicopathological characteristics associated with better oncological outcomes compared with older patients. …”
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Desmoid-type fibromatosis of the breast: a case report and literature review by Zijun Zhao, Qingyao Shang, Chenxuan Yang, Jiaxiang Liu, Shanqing Liu, Xiaoqian Li, Xiyu Kang, Jiaxian Yue, Xin Wang, Xiang Wang

“…It has a high recurrence rate, although distal metastasis is uncommon. It resembles breast cancer clinically, and histological pathology is the only approach to a confirmed diagnosis. …”
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MEK Inhibition Targets Cancer Stem Cells and Impedes Migration of Pancreatic Cancer Cells In Vitro and In Vivo by Karolin Walter, Kanishka Tiwary, Marija Trajkovic-Arsic, Ana Hidalgo-Sastre, Laura Dierichs, Sven T. Liffers, Jiangning Gu, Johann Gout, Lucas-Alexander Schulte, Jan Münch, Thomas Seufferlein, Bruno Sainz, Jens T. Siveke, Eva Rodriguez-Aznar, Patrick C. Hermann

“…While pancreatic cancer is particularly difficult to treat, patients usually succumb not to the growth of the primary tumor, but to extensive metastasis; therefore, strategies to reduce the migratory and metastatic capacity of pancreatic cancer cells merit close attention. …”
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A scoping review examining the relationship between green tea and skin cancers by Ram Lakhan, Louisa Summers, Olugbemiga Ekundayo, Jedidiah Radosevich, Sierra Turner, Sangyal Dorjee, Vinayak K. Nahar, Manoj Sharma

“…Particularly, EGCG has been found as a contributing factor to inhibit cell invasion, angiogenesis, and metastasis in skin cancer. Discussion: Use of green tea and its extracts may offer promising implications for use in humans about prevention and retarding the progress of skin cancers but at present, the data are very limited. …”

SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma ce... by Tianci Han, Xiaoqi Guo, Junwei Xie, Wei Tong, Liang Zhang

“…Abstract Objective Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors with a high metastasis rate and a poor prognosis. ETS variant transcription factor 1 (ETV1) plays an important role in multiple malignancies. …”
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Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach by Sakhr Alshwayyat, Mahmoud Bashar Abu Al Hawa, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Siya sawan, Ghaith Heilat, Hanan M. Hammouri, Sara Mheid, Batool Al Shweiat, Hamdah Hanifa

“…Conclusion: Age, lymph node metastasis, and ER status are crucial prognostic indicators for BACC. …”
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Utilizing machine-learning techniques on MRI radiomics to identify primary tumors in brain metastases by W. L. Yang, W. L. Yang, X. R. Su, S. Li, K. Y. Zhao, Q. Yue

“…BMGiT.ConclusionThe machine learning-based radiomics model demonstrates significant potential in distinguishing the primary sites of brain metastases, and may assist screening of primary tumor when brain metastasis is suspected whereas history of primary tumor is absent.…”
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Serum albumin-carcinoembryonic antigen ratio as an effective clinical tool for predicting recurrence and overall survival in patients with rectal cancer by Hailun Xie, Hailun Xie, Lishuang Wei, Shuangyi Tang, Jialiang Gan, Jialiang Gan

“…The predictive ability of the model was evaluated using the C-index and calibration curve, and its prognostic predictive abilities were compared to those of traditional Tumor Node Metastasis (TNM) stage using discriminant indices.ResultsA total of 736 patients with rectal cancer were included in the study. …”
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LncRNA GAS5 inhibits glioma progression through miR-135b-5p/APC axis by ZHANG Jidong, WANG Yutao, JI Jianwen

“…Objective‍　‍To explore the interaction between long non-coding RNA growth arrest-specific 5 (GAS5) and miR-135b-5p/adenomatous polyposis coli (APC) axis, and to elucidate its biological function in the proliferation, metastasis and invasion of glioma. Methods‍　‍The relationship of GAS5 expression level with survival rate of glioma patients was analyzed based on CGGA database. qRT-PCR was used to detect the expression level of GAS5 in glioma tissues and cell lines. …”
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Prognostic value of matrix metalloproteinases and transforming growth factor – β in kidney cancer by A. I. Tarasenko, A. N. Rossolovskiy, O. L. Berezinets, A. B. Bucharskaya, S. S. Pakhomiy, A. O. Efimova, G. N. Maslyakova

“…Markers of oncogenesis and nephrofibrosis TGF‑β1 and MMP‑9 provide an opportunity for non‑invasive monitoring of tumor progression and probability of metastasis in the clinical setting. Serum MMP‑9 are a reliable predictor of tumor growth. …”
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Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome with Purely Osteolytic, Not Osteosclerotic, Lesions Mimicking a Malignant Tumor by Hideyuki Kinoshita, Takeshi Ishii, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Tsukasa Yonemoto

“…Although SAPHO syndrome was suspected because of palmoplantar pustulosis, based on radiologic findings, bone metastasis of a malignant tumor or chronic bacterial osteomyelitis owing to a purely osteolytic lesion was suspected. …”
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Deciphering the potential ability of DExD/H-box helicase 60 (DDX60) on the proliferation, diagnostic and prognostic biomarker in pancreatic cancer: a research based on silico, RNA-... by Dongdong Zhang, Enze Zhang, Ying Cai, Yixin sun, Peiji Zeng, Xiaohua Jiang, Yifan Lian

“…The mRNA expression level of DDX60 was correlated with lymph node metastasis and grade in clinical pancreatic patients. …”
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Testicular Cancer Presenting as Gastric Variceal Hemorrhage by Carlos Eduardo Salazar-Mejía, David Hernández-Barajas, Edio Llerena-Hernández, José Luis González-Vela, María Inés Contreras-Salcido, Adriana González-Gutiérrez, Omar David Borjas-Almaguer, Luis Alberto Pérez-Arredondo, Blanca Otilia Wimer-Castillo

“…The symptomatology caused by this tumor varies according to the site of metastasis. We present the case of a 26-year-old male who arrived to the emergency department with hematemesis. …”
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Radiological and Clinical Features and Outcomes of Patients with Primary Pulmonary Salivary Gland-Type Tumors by Xiaoyu Han, Jianchu Zhang, Jun Fan, Yukun Cao, Jin Gu, Heshui Shi

“…The overall survival (OS) at 3 and 5 years was 90.9% and 72.2% in all patients, respectively. Tumor-node-metastasis (TNM) stage, surgery, and patient age were associated with OS (p≤0.001, p=0.001, and p=0.001, respectively). …”
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Plasma S100A8/A9 level predicts response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer by Tadahiro Kuribayashi, Rie Kinoshita, Kiichiro Ninomiya, Go Makimoto, Toshio Kubo, Kammei Rai, Eiki Ichihara, Katsuyuki Hotta, Masahiro Tabata, Yoshinobu Maeda, Katsuyuki Kiura, Shinichi Toyooka, Masakiyo Sakaguchi, Kadoaki Ohashi

“…Multivariate analysis revealed that PS ≥ 2, liver metastasis, and high plasma S100A8/A9 levels were significantly associated with short TTF and OS. …”
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Thyroid Dysfunction After Intensity-Modulated Radiotherapy and PD⁃1 Inhibitor Treatment for Locally Advanced Nasopharyngeal Carcinoma by Shang K, He Q, Xu X, Luo X, Zhao C, Liu L, Li Z, Li Y, Jin F

“…Patients with thyroid dysfunction had longer overall survival, progression-free survival, and distant metastasis-free survival at both one and two years compared to patients with normal thyroid function, but the difference was not statistically significant (p > 0.05). …”
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