Frontier machine learning techniques for melanoma skin cancer identification and categorization: An in-Depth review by Viomesh Singh, Kavita A. Sultanpure, Harshwardhan Patil

“…Failure to diagnose it at its incipient stages may lead to metastasis, significantly elevating mortality rates. …”
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NGF-TrkA Axis Enhances PDGF-C-Mediated Angiogenesis in Osteosarcoma via miR-29b-3p Suppression: A Potential Therapeutic Strategy Using Larotrectinib by Sheng-Mou Hou, Ching-Yuan Cheng, Wei-Li Chen, En-Ming Chang, Chih-Yang Lin

“…Angiogenesis plays a critical role in osteosarcoma (OS) growth and metastasis. While nerve growth factor (NGF) is implicated in cancer progression, its role in OS angiogenesis remains unclear. …”
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Alveolar Soft Part Sarcoma of Urinary Bladder Occurring as a Second Primary Malignancy: A Case Report and Literature Review by Manint Usawachintachit, Piyada Sitthideatphaiboon, Voranuch Thanakit, Sulada Pukiat, Kamol Panumatrassamee, Julin Opanuraks, Apirak Santi-Ngamkun

“…Chest and abdominal computed tomography showed no evidence of metastasis. He was treated with partial cystectomy and left ureteral reimplantation with negative surgical margin. …”
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The Current Role of Osteoclast Inhibitors in Patients with Prostate Cancer by Diomidis Kozyrakis, Dionyssios Paridis, Stefanos Perikleous, Konstantinos Malizos, Anastasios Zarkadas, Antonios Tsagkalis

“…In metastatic-free castrate-sensitive high-risk PCa patients, ZA has not shown any efficacy in preventing osseous metastasis, and evidence is lacking in favor or against the use of DEN. …”
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Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer by Aijun Sun, Xiaonan Sheng, Jinhai Tang, Zhenfeng Yu, Jian Zhang

“…Breast cancer is the 3rd most common type of malignant tumor worldwide with high heterogeneity, frequent recurrence, and high metastasis tendency. In this study, we aimed to demonstrate the value of extracellular matrix- (ECM-) related genes in breast cancer patients. …”
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B-Flow Twinkling Sign in Preoperative Evaluation of Cervical Lymph Nodes in Patients with Papillary Thyroid Carcinoma by Giuseppina Napolitano, Antonio Romeo, Andrea Bianco, Maurizio Gasperi, Pio Zeppa, Luca Brunese

“…Papillary thyroid cancer (PTC) is the most common histologic type of differentiated thyroid cancer. The first site of metastasis is the cervical lymph nodes (LNs). The ultrasonography (US) is the best diagnostic method for the detection of cervical metastatic LNs. …”
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Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers by A.N.K.V. Sravani, John Thomas

“…The epithelial-to-mesenchymal transition (EMT) is a crucial step in metastasis formation. It enhances the ability of cancer cells' to self-renew and initiate tumors, while also increasing resistance to apoptosis and chemotherapy. …”
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A Lifelong Smoker with Hypopituitarism: Rethinking the Hypothesis of a Tumor in the Hypophysis by Nestoras Mathioudakis, Alfredo Quinones-Hinojosa, Roberto Salvatori, Shehzad Basaria

“…This case illustrates the need for maintaining a high index of suspicion for pituitary metastasis in patients with known risk factors for malignancy.…”
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Advanced Epithelioid Malignant Peripheral Nerve Sheath Tumor Showing Complete Response to Combined Surgery and Chemotherapy: A Case Report by Tomohiro Minagawa, Ryuta Shioya, Chigusa Sato, Ryuji Shichinohe, Go Yasui, Kohsuke Ishikawa, Hiroko Takahashi

“…No evidence of recurrence or metastasis was observed at the 12-month followup after the first operation. …”
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The heat of the battle: inflammation’s role in prostate cancer development and inflammation-targeted therapies by Ujjawal Sharma, Anidrisha Sahu, Himanshu Shekhar, Bunty Sharma, Shafiul Haque, Damandeep Kaur, Hardeep Singh Tuli, Astha Mishra, Faraz Ahmad

“…From cellular and molecular elements of the inflammatory microenvironment to mechanisms like epithelial-to-mesenchymal transition (EMT), reactive oxygen species (ROS) generation, and inflammasome activation, these processes highlight inflammation’s influence on PC progression and metastasis. Furthermore, this review discusses current therapeutic strategies targeting inflammation in PC management and identifies future research directions aimed at unraveling the complexities of inflammation-induced PC (Supplementary Fig. 1). …”
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Sex differences in presentation of pheochromocytoma and paraganglioma by Nora Azin Ali, Jan Calissendorff, Jan Calissendorff, Henrik Falhammar, Henrik Falhammar

“…No differences between sexes were found in biochemical, genetical or histopathological results, or presence of metastasis at diagnosis.ConclusionsThe reported symptoms by patients with PPGL were generally similar between the sexes, except for pallor and sweating. …”
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Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells by Chaoqun Huang, Wei Liu, Xiaochuan Zhao, Libin Zhao, Fuxiang Wang

“…In summary, our data illustrate that inhibition of HBx effectively suppressed proliferation and metastasis and induced apoptosis of liver cancer cells, which might be partially reversed by XB130. …”
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Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells by Mabeta Peace, Pavić Kristina, Zorc Branka

“…We further investigated their effects on two important processes during metastasis, namely, migration and invasion. Compounds 1 and 3 inhibited the migration and invasion of MCF-7 cells, while compound 2 had a marginal effect.…”
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Corrigendum to “Cell surface GRP78-directed CAR-T cells are effective at treating human pancreatic cancer in preclinical models” [Translational Oncology volume 39 (2024) 101803]... by Yuncang Yuan, Jiawei Fan, Dandan Liang, Shijie Wang, Xu Luo, Yongjie Zhu, Nan Liu, Tingxiu Xiang, Xudong Zhao

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Exploring the prognosis of calponin h1 in carcinogenesis: A novel target in biomedical research by Roshna Sankar, Sharon John, Priya Devi, Sameer Gupta, Shalini Gupta

“…Stromal myofibroblasts play a crucial role in tumor invasion and metastasis by their capacity to alter the extracellular matrix. …”
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Late-Onset Bilateral Choroidal Metastases from Clear Cell Renal Cell Carcinoma by Constantinos D. Georgakopoulos, Athina Pallikari, Panagiotis Plotas, Olga E. Makri

“…The time interval between primary malignancy and choroidal metastasis is reported to be 12-96 months. Bilateral choroidal metastases have been described in 9 cases. …”
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Development and Validation of an Immunotherapy-Related Prognostic Signature Based on Lymph Node Ratio for Gastric Cancer by Jianxin Li, Ting Han, Xin Wang, Yinchun Wang, Xuan Chen, Wangsheng Chen, Qingqiang Yang

“…The long-term prognosis of gastric cancer (GC) remains poor due to postoperative recurrence and metastasis. The increasing evidence show that the lymph node ratio (LNR) serves as an independent prognostic factor in patients with GC. …”
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Active surveillance for adult low-risk papillary thyroid microcarcinoma—a review focused on the 30-year experience of Kuma Hospital— by Yasuhiro Ito, Akira Miyauchi, Makoto Fujishima, Masashi Yamamoto, Takahiro Sasaki

“…This review notes that one patient showed lung metastasis after conversion surgery (CS) following AS, but there are no reports of patients dying of thyroid carcinoma during or after AS. …”
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Evaluation of immunohistochemical expression of novel neuroendocrine marker INSM1 and histological tumor growth pattern in well-differentiated neuroendocrine tumors of the appendix... by Ali Koyuncuer, Tolga Canbak, Aylin Acar, Onur Şahin

“…Eight percent of the tumors invaded the mucosa/submucosa, 34.3% showed invasion into the muscularis propria, 57.1% showed invasion into the subserosa or mesoappendix, LN metastasis was observed in two patients, lymph-vascular invasion in two patients, and perineural invasion in five patients. …”
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Recent methods for the diagnosis and differentiation of ameloblastoma: a narrative review by Ke Hu, Xudong Zhang, Ruixue Chen, Xiangjun Li

“…Panoramic radiography, computed tomography, and magnetic resonance imaging have been used to detect ameloblastoma, whereas fine-needle aspiration cytology and biopsies have been used to enhance diagnostic precision and clinical diagnosis. 18F-fluorodeoxyglucose (FDG) and FDG positron emission tomography(PET) have been used to detect metastasis of ameloblastoma to determine the prognosis of the disease. …”
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