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121
Features of diagnosis and treatment of gastrointestinal stromal tumors
Published 2018-08-01“…In the remote period after surgery one patient died due to tumor metastasis, in 7 patients GIST was primarily diagnosed at the autopsy. …”
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122
A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology
Published 2025-02-01“…Numerous studies have demonstrated that Schisandrin B exhibits significant antitumor activity against various malignant tumors in preclinical studies, which is achieved by inhibiting cell proliferation and metastasis and promoting apoptosis. As a potential antitumor agent, Schisandrin B holds broad application prospects. …”
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123
Esophageal submucosal gland duct adenoma: a case report and literature review
Published 2025-02-01“…Local tumor resection was performed, the longest follow-up period was 132 months of the 20 patients, the prognosis was favorable, and no recurrence or metastasis.DiscussionESGDA is more common in the lower esophagus in elderly patients, and its clinical symptoms are atypical. …”
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124
A new strategy for the treatment of advanced ovarian cancer: utilizing nanotechnology to regulate the tumor microenvironment
Published 2025-02-01“…In the non-immune TME, mechanisms such as apoptosis inhibition, DNA damage response (DDR), and epithelial-mesenchymal transition (EMT) can promote tumor growth, metastasis, and drug resistance. Despite the challenges posed by the TME in the treatment of AOC, the unique biological advantages of nanoparticles (NPs) make it possible to regulate the TME. …”
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125
Unraveling the PVTGlu-mPFCGlu circuit: A new frontier in chronic pain management for bone cancer pain
Published 2025-03-01“…Bone cancer pain (BCP) is a type of ongoing or breakthrough pain caused by a primary bone tumor or bone metastasis. BCP impairs patients’ quality of life. Depending upon clinical observations, the administration of centrally acting analgesic has been associated with the alleviation of pain symptoms BCP patients. …”
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126
Tumor microbiome: roles in tumor initiation, progression, and therapy
Published 2025-02-01“…Abstract Over the past few years, the tumor microbiome is increasingly recognized for its multifaceted involvement in cancer initiation, progression, and metastasis. With the application of 16S ribosomal ribonucleic acid (16S rRNA) sequencing, the intratumoral microbiome, also referred to as tumor-intrinsic or tumor-resident microbiome, has also been found to play a significant role in the tumor microenvironment (TME). …”
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127
Colonic stenting in acute malignant large bowel obstruction: audit of efficacy and safety in a Singapore tertiary referral centre
Published 2023-10-01“…Local recurrence and distant metastasis were observed in 4 (10.3%) and 5 (12.8%) patients, respectively. …”
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128
Phosphaturic mesenchymal tumor: Clinicopathological features with outcomes in 10 patients with review of literature
Published 2024-04-01“…In five cases where follow-up was available, there was complete resolution of symptoms post-resection with no recurrence or metastasis. All those patients were free of disease until the last follow-up. …”
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129
Impact of Paracoccus sp. EGY7 carotenoids on triple-negative breast cancer cells: invitro study
Published 2025-02-01“…They effectively promote apoptosis and prevent metastasis, crucial for disease advancement in cancer cells.…”
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130
The Effect of Tumor Angiogenesis Agents on Tumor Growth Dynamics: A Mathematical Model
Published 2025-01-01“…However, increasing inhibitor factors via anti-angiogenic drugs would be a more effective therapeutic approach to eradicate metastasis. …”
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131
OSTEOSARCOMA HAS NOT BECOME ATTENTION TO SOCIETY PROFILE OF OSTEOSARCOMA PATIENTS AT DR. SOETOMO GENERAL HOSPITAL SURABAYA "A RETROSPECTIVE STUDY”
Published 2019-12-01“…Most common cause of mortality was the metastasis. Conclusion: Awareness of the society about the cancer sign of cancer and desire to use medical treatment as a priority is still low. …”
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132
Intrathecal trastuzumab: immunotherapy improves the prognosis of leptomeningeal metastases in HER-2+ breast cancer patient
Published 2015-09-01“…However, spinal cord C-1 metastasis was not fully controlled with IT trastuzumab, ultimately leading to the patient’s respiratory compromise. …”
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133
Hijacking of the nervous system in cancer: mechanism and therapeutic targets
Published 2025-02-01“…First, we elucidated how the nervous system accelerates tumor growth, metastasis, and the tumor microenvironment both directly and indirectly through the action of signaling molecules. …”
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134
Intracranial ewings sarccoma mimicking middle 1/3rd parasagittal meningioma
Published 2025-02-01“…Intracranial Ewing’s Sarcoma may be found as a result of metastasis from extracranial sites. Primary Ewing’s Sarcoma affecting the central nervous system (CNS) is rare, which is commonly intraparenchymal located either supratentorial or in the spinal cord. …”
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135
Predicting the risk of bone metastases in patients with newly diagnosed prostate cancer - Development and validation of a nomogram model.
Published 2025-01-01“…<h4>Objectives</h4>The aim of this study was to develop and validate a nomogram model that predicts the risk of bone metastasis (BM) in a prostate cancer (PCa) population.…”
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136
Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer
Published 2025-02-01“…Abstract Gastric cancer (GC) is one of the most common tumors; one of the reasons for its poor prognosis is that GC cells can resist normal cell death process and therefore develop distant metastasis. Cuproptosis is a novel type of cell death and a limited number of studies have been conducted on the relationship between cuproptosis-related genes (CRGs) in GC. …”
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137
Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis
Published 2025-02-01“…Cohort analysis revealed a significant positive correlation between metastasis rate and radiotherapy use (Spearman's rho = 0.828, p = 0.042) and between chemotherapy and hormonal therapy use (rho = 0.69, p = 0.04). …”
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138
New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine
Published 2025-02-01“…In this paper, we review the expression and significance of TRPV1 receptor in various cancer cell types, the role of TRPV1 in the apoptosis-proliferation balance, cancer cell invasion and metastasis, and tumor micro-environment, with emphasis on the mechanisms by which TRPV1 receptor mediates inflammatory response, immune system, and thus regulates cancer. …”
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139
Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on P...
Published 2025-01-01“…Wound healing showed a decreased cell migration on both cell lines an important stage of metastasis. The study suggests that the study molecule can be a promising chemotherapeutic agent in the development of new anticancer drugs. …”
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140
RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients
Published 2024-10-01“…The metabolic pathway of polyamines is crucial in breast cancer progression, with a strong association to the increased capabilities of tumor cells for proliferation, invasion, and metastasis. Methods We used a multi-omics approach combining bulk RNA sequencing and single-cell RNA sequencing (scRNA-seq) to study polyamine metabolism. …”
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