Systemic Lymphadenectomy Cannot Be Recommended for Low-Risk Corpus Cancer by Takao Hidaka, Akitoshi Nakashima, Tomoko Shima, Toru Hasegawa, Shigeru Saito

“…Between 1998 and 2007, a total of 83 patients with low risk corpus cancer (endometrioid type, grade 1 or 2, myometrial invasion ≦50%, and no intraoperative evidence of macroscopic extrauterine spread, including pelvic and paraaortic lymph node swelling and adnexal metastasis) underwent the total abdominal hysterectomy and bilateral salpingo-oophorectomy without lymphadenectomy. …”
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Out of place: thoracic splenosis—a case report by Gaston Becherano, Eitan Podgaetz, Shair Ahmed, Sigrid Ringenberg, Gary Schwartz

“…Surgical resection may be necessary in oncological cases to rule out metastasis.…”
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Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node by Jien Shim, Jianyu Rao, Run Yu

“…Six years after her initial treatments, she had biopsy-proven cervical lymph node metastasis. The patient opted not to undergo any further treatment. …”
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An Optimal Algorithm for Determining Risk Factors for Complex Diseases: Depressive Disorder, Osteoporosis, and Fracture in Young Patients with Breast Cancer Receiving Curative Surg... by Chieh-Yu Liu, Chun-Hung Chang

“…The results revealed that depressive disorder, osteoporosis, and fracture were clustered with liver cirrhosis, chronic obstructive pulmonary disease (COPD), distant metastasis, and primary metastatic and adjuvant therapies, namely, chemotherapy, radiotherapy, tamoxifen, aromatase inhibitors, and trastuzumab. …”
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A Liver Transplant for Local Control in a Pediatric Patient with Metastatic TFE3-Associated Perivascular Epithelioid Cell Tumor (PEComa) to the Liver by Whayoung Lee, Josephine HaDuong, Aaron Sassoon, Tuan Dao, Ali Nael

“…Here, we present the first case of a malignant pediatric colonic TFE3-associated PEComa with isolated liver metastasis leading to liver transplantation for the local control.…”
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LINC01614 Promotes Colorectal Cancer Cell Growth and Migration by Regulating miR-217-5p/HMGA1 Axis by Jiwei Jia, Pei Guo, Li Zhang, Wenqing Kong, Fangfang Wang

“…LINC01614 knockdown repressed the proliferation and metastasis capacity of CRC cell lines. Consistently, an in vivo LINC01614 deficiency model exhibited slow tumor growth rate. …”
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Breast cancer metastases in central nervous system. Case report and review of literature by I. Radzevičiūtė, R. Pačinskaitė, R. Gleiznienė

“…A very aggressive intraventricular, leptomeningeal spread to the central nervous system is also possible; however, it is a rare localization of breast cancer metastasis. Magnetic resonance imaging (MRI) is the most sensitive diagnostic tool for the detection of brain metastases. …”
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Classification of Melanoma Cancer Using Deep Convolutional Neural Networks by Emrah Dönmez, Ali Güneş

“…Melanoma, a form of skin cancer with a high potential for metastasis, requires early detection to significantly improve treatment success and prevent further spread across the skin. …”
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Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies by Elisa Ferretti, Vito Pistoia, Anna Corcione

“…In tumors the interaction between cancer cells and cellular microenvironment creates a context that may promote tumor growth, increase tumor survival, and facilitate metastasis. Therefore the role of the CX3CL1/CX3CR1 has attracted interest as to the development of potential therapeutic approaches. …”
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Integrins identified as potential prognostic markers in osteosarcoma through multi-omics and multi-dataset analysis by Lei Cui, Shuai Zhao, Hai long Teng, Biao Yang, Qian Liu, An Qin

“…Assessing its prognosis is challenging due to the complex roles of integrins in tumor development and metastasis. This study utilized 209,268 osteosarcoma cells from the GEO database to identify integrin-associated genes using advanced analysis methods. …”
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Complete Radiologic Response of Metastatic Pancreatic Ductal Adenocarcinoma to Microwave Ablation Combined with Second-Line Palliative Chemotherapy by Hakon Blomstrand, Karin Adolfsson, Per Sandström, Bergthor Björnsson

“…Surprisingly, the response to second-line palliative chemotherapy with 5-fluorouracil-oxaliplatin was excellent; in combination with the ablation of a liver metastasis, this treatment regimen resulted in a complete radiological response and an 11-month treatment-free interval with a sustained good performance status.…”
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Evaluation of the role of unconventional prefoldin RPB5 interactor (URI1) in hepatitis B virus infection by Karolína Štaflová, Aleš Zábranský, Iva Pichová

“…HBV infection has been shown to increase the expression of the unconventional prefoldin RPB5 interactor (URI1), a cellular protein that promotes liver tumorigenesis and HCC metastasis. Our study investigated the role of URI1 in HBV infection in vitro. …”
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Galectins as New Prognostic Markers and Potential Therapeutic Targets for Advanced Prostate Cancers by Diego J. Laderach, Lucas Gentilini, Felipe M. Jaworski, Daniel Compagno

“…This review both discusses whether the “galectin-signature” might serve as a reliable biomarker for the identification of patients with high risk of metastasis and assesses the galectin-glycan lattices as potential novel targets for anticancer therapies. …”
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Bilateral Numb Chin Syndrome as the Initial Presentation of Burkitt’s Lymphoma/Leukemia: A Report of Two Cases and Review of the Literature by Hussein Algahtani, Bader Shirah, Wafaa Bassuni, Reem Adas

“…This syndrome may be the first symptom of underlying malignancy or the first sign of recurrence and metastasis in patients with preexisting cancer. In this article, we present two cases with bilateral numb chin syndrome as the first manifestation of Burkitt’s lymphoma/leukemia and review the relevant literature. …”
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Integrin-Linked Kinase: A Multi-functional Regulator Modulating Extracellular Pressure-Stimulated Cancer Cell Adhesion through Focal Adhesion Kinase and AKT by Shouye Wang, Marc D. Basson

“…Cell adhesion is important in cancer metastasis. Malignant cells in cancer patients may be exposed to physical forces such as extracellular pressure and shear, that stimulate their adhesion to matrix proteins, endothelium and surgical wounds. …”
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The Extent of Lymphadenectomy at the Time of Radical Cystectomy for Bladder Cancer and its Impact on Prognosis and Survival by David Y. Josephson, John P. Stein

“…Furthermore, the stage of the primary bladder tumor, total number of lymph nodes removed, and the lymph node tumor burden are shown to be important prognostic variables in patients undergoing cystectomy with pathologic evidence of lymph node metastasis. Radical cystectomy provides not only excellent local cancer control with low pelvic recurrence rates, but also the best long-term survival. …”
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Hypercalcemia of Malignancy in Thymic Carcinoma: Evolving Mechanisms of Hypercalcemia and Targeted Therapies by Cheng Cheng, Jose Kuzhively, Sanford Baim

“…We report a 26-year-old male with newly diagnosed undifferentiated thymic carcinoma associated with HCM. Osteolytic metastasis-related hypercalcemia was presumed to be the etiology of hypercalcemia that responded to intravenous hydration and bisphosphonate therapy. …”
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Metastatic Renal Cell Cancer to Thyroid Diagnosed by Endoscopic Ultrasound Guided Fine Needle Aspiration Technique by Yousef Abdel-Aziz, Tariq Hammad, Mohamad Nawras, Hayder Abdulwahid, Ali Nawras

“…We present a case of secondary thyroid cancer from renal cell carcinoma (RCC) metastasis, diagnosed by thyroid EUS-fine needle aspiration (FNA) approach that was done for staging of esophageal adenocarcinoma, in a patient with 11-year history of complete right nephrectomy for RCC. …”
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Deep Neck Infection: A Typical Presentation of Papillary Thyroid Cancer by Apichana Mahattanapreut, Rangsima Aroonroch, Chalermchai Chintrakarn, Chutintorn Sriphrapradang

“…Nevertheless, head and neck squamous cell carcinoma is the most common primary head and neck cancer, which could present with cervical metastasis and subsequently becomes infected. Papillary thyroid cancer has a naturally indolent course, and most patients present with a thyroid nodule. …”
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Mullerian Adenosarcoma of Uterus with Sarcomatous Overgrowth and Heterologous Component Associated with Stromal Deposit in Omentum: A Case Report and Review of the Literature by Anuradha Sinha, Jyoti Prakash Phukan, Sanjay Sengupta, Paulami Guha

“…MA is considered as a low-grade malignant tumor, but MASO is a high-grade tumor frequently associated with invasion and metastasis with poor treatment outcome. Because of its rarity, correct identification of these tumors and distinction from other uterine sarcomas are a challenging job and hence its morphological features merits attention.…”
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