Requiem for the Term ‘Carcinoid Tumour’ in the Gastrointestinal Tract? by Runjan Chetty

“…In addition, a recently suggested tumour-node-metastasis scheme has been proposed and awaits clinical validation and acceptance. …”
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Immunosuppressive Role of Myeloid-Derived Suppressor Cells and Therapeutic Targeting in Lung Cancer by Jie Ma, Huaxi Xu, Shengjun Wang

“…However, the occurrence, metastasis, and survival of cancer is the result of multiple factors and multiple mechanisms, so combined treatments using different strategies will become the major therapy method for lung cancer in the future.…”
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Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway by Nazir Nausheen, Waqar Arbaz, Zaib Khan Amir, Ali Khan Ayaz, Aziz Tariq, Alasmari Abdullah F.

“…Anti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. Natural sources like plants are currently being explored for its antiangiogenic activity as they are factories of various phytochemicals. …”
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Dedifferentiated Low-Grade Central Osteosarcoma of the Mandible by Kenji Yamagata, Naomi Ishibashi-Kanno, Ryota Matsuoka, Fumihiko Uchida, Satoshi Fukuzawa, Hiroki Bukawa

“…The patient showed no recurrence or lung metastasis 3 years after the final surgery.…”
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Plasmacytoid Urothelial Carcinoma of the Bladder That Manifests Disseminated Carcinomatosis of the Bone Marrow: A Case Report of Extremely Rapid Progression by Nobuhiko Shimizu, Yoshinobu Moritoki, Nao Katsumi, Takahiro Yanase, Teruaki Sugino, Kazuhiro Kanemoto, Hidetoshi Akita, Takahiro Yasui

“…In this paper, we report the case of a patient with PUC who developed widespread bone metastasis only 6 weeks after RC, which resulted in death within 2 months postoperatively.…”
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Laryngeal Chondrosarcoma as a Rare Cause of Subglottic Stenosis by Kerem Kökoğlu, Özlem Canöz, Serap Doğan, Emrah Gülmez, İmdat Yüce, Sedat Çağlı

“…A submucous mass is usually seen in physical examination with an intact mucosa. Distant metastasis is rare in CSs. Main treatment is surgical excision. …”
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An Update on the Changing Indications for Androgen Deprivation Therapy for Prostate Cancer by Kristene Myklak, Shandra Wilson

“…The benefits of ADT are evident neoadjuvantly and adjuvantly in patients treated with external beam radiation therapy for intermediate- and high-risk disease, in patients who have undergone prostatectomy with lymph node involvement, in high-risk patients after definitive therapy, and in patients who have developed progression or metastasis. Finally, this paper reviews the risks and benefits of each of these scenarios and the risks of androgen deprivation in general, and it delineates the areas where ADT was previously recommended, but where evidence is lacking for its additional benefit.…”
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Aggressive Behaviour of Metastatic Melanoma in a Patient with Neurofibromatosis Type 1 by Robert W. Foley, Robert M. Maweni, Aurelie Fabre, David G. Healy

“…We describe the case of a solitary lung metastasis in a patient with neurofibromatosis type 1 without an identifiable primary tumour. …”
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Rhabdomyosarcoma Orbita by Elfi Risalma Puteri, Ardizal Rahman

“…Tumor ini merupakan tumor yang agresif, dengan kecenderung terjadi invasif lokal dan dapat terjadi rekurensi lokal, dengan metastasis secara hematogen dan limfatik. Dilaporkan kasus Rhabdomyosarcoma orbita pada anak laki-laki umur 12 tahun dengan progresivitas yang cepat , dengan hasil pemeriksaan patologi anatomi menunjukkan suatu embryonal rhabdomyosarcoma retroorbita serta penatalaksanaannya. …”
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The Role and Therapeutic Potential of Endothelial Progenitor Cells in Tumor Neovascularization by Branislava Janic, Ali S. Arbab

“…Although the cellular and molecular mechanisms of tumor growth and metastasis are not completely understood, it is established that formation and growth of new blood vessels is a conditio sine qua non for tumor survival, growth, and expansion. …”
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Case Report and Literature Review of a Pathologic Mandibular Fracture from Metastatic Esophageal Adenocarcinoma by Daniel C. O’Brien, Garrett Jones, Maggie Yell, Jason McChesney

“…Distant metastasis to the jaws, including the maxilla or mandible, is very rare. …”
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The Role of Decorin in Autoimmune and Inflammatory Diseases by Yuanji Dong, Jixin Zhong, Lingli Dong

“…Decorin has been shown to be involved in wound repair, cell cycle, angiogenesis, tumor metastasis, and autophagy. Recent evidence indicates that it also plays a role in immune regulation and inflammatory diseases. …”
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Palpable Penile Metastases: A Bizarre Presentation of Rectal Adenocarcinoma by Liza Cholin, Sarah Perz, Furman Mahmood, Saleem Zafar

“…Metastasis to the penis is an uncommon occurrence, with only about 370 cases reported in the literature to date. …”
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Combination of Anti-programmed Cell Death Protein 1 and Antiangiogenesis Displaying a Response Disparity between Pulmonary and Nonpulmonary Metastases by Bing-Syuan Chung, Peng-Chan Lin, Shang-Hung Chen, Yu-Min Yeh

“…These findings suggest that lung metastasis might have a distinct tumor immune microenvironment, and further studies to investigate the efficacy of PD-1/PD-L1-based combination therapy in patients with lung-limited metastases are warranted.…”
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Lipid Histiocytosis of the Gallbladder Neck Lymph Node by Adriana Handra-Luca, Mohamed Habib Ben Romdhane, Beate Katharina Straub

“…While such lesions may remain unidentified on imaging procedures, the microscopic analysis may require special stains and immunohistochemistry for ruling out adenocarcinoma metastasis.…”
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Primary Lymphoepithelioma-Like Carcinoma of the Conjunctiva Metastatic to Regional Lymph Nodes and Parotid Gland in a Mexican Patient by Ana Lía Díazceballos-García, Sebastian Diener-Kudisch, Abelardo A. Rodriguez Reyes, Ángel Nava-Castañeda

“…She developed parotid and neck lymph node metastasis treated with concurrent radiotherapy. The patient had remained disease-free for 3 years. …”
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Small Bowel Intussusception due to Metastasized Sarcomatoid Carcinoma of the Lung: A Rare Cause of Intestinal Obstruction in Adults by Ali Guner, Savaş Karyagar, Ayten Livaoglu, Can Kece, Uzer Kucuktulu

“…In this paper, we aim to describe a patient with small bowel intussusception caused by an isolated small bowel metastasis of the sarcomatoid carcinoma of the lung by reviewing the literature.…”
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Primitive myxoid mesenchymal tumor of infancy, an enigmatic entity: A case report by Malini Goswami

“…It can show aggressive local infiltration of surrounding structures and frequent relapses but rare metastasis. Morphologically, it is characterized by a proliferation of immature mesenchymal cells in a myxoid background with mild cytologic atypia and branching vessels. …”
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Breast Cancer in Men: a Rare Case by Lidia Torres Aja, José Alberto Puerto Lorenzo

“…In addition to other examinations, an excisional biopsy of a small fragment of the lesion was performed with a paraffin study, which reported cutaneous metastasis of a shell breast carcinoma according to its clinical presentation. …”
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Genetics of Uveal Melanoma and Cutaneous Melanoma: Two of a Kind? by Thomas van den Bosch, Emine Kilic, Dion Paridaens, Annelies de Klein

“…Especially in UM, where the overall risk of metastasis is high (45%), genetic research might aid clinicians in selecting high-risk patients for future systemic adjuvant therapies.…”
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