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721
Cell Counts, rather than Proportion, of CD8/PD-1 Tumor-Infiltrating Lymphocytes in a Tumor Microenvironment Associated with Pathological Characteristics of Chinese Invasive Ductal...
Published 2019-01-01“…The proportion of CD8+/PD-1- TILs was 16% among patients with axillary lymph node metastasis, significantly lower than those without metastasis (24%). …”
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722
miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5
Published 2021-01-01“…Our results demonstrated that miR-370-3p significantly promoted proliferation, metastasis, and stemness of breast cancer in vitro and in vivo. …”
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723
HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop
Published 2022-01-01“…Hypoxia has crucial functions in the development and metastasis of cervical cancer by inducing the expression of numerous genes, including microRNA genes. …”
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724
The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review
Published 2020-01-01“…Malignant tumors still pose serious threats to human health due to their high morbidity and mortality. Recurrence and metastasis are the most important factors affecting patient prognosis. …”
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725
Outcomes of Recurrent Head and Neck Cutaneous Squamous Cell Carcinoma
Published 2011-01-01“…Distant metastasis was a strong indicator of poor overall survival (P<.001). …”
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726
Unveiling the complex double-edged sword role of exosomes in nasopharyngeal carcinoma
Published 2025-01-01“…Exosomes could serve as biomarkers and therapeutic agents, as well as the molecular mechanisms by which they promote cell growth, angiogenesis, metastasis, immunosuppression, radiation resistance, and chemotherapy resistance in NPC. …”
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727
Primary leiomyosarcoma of the scalp: a case report and review of the literature
Published 2025-02-01“…Background and importanceLeiomyosarcoma is a rare and aggressive malignant tumor with a high potential for relapse and metastasis. Correct and timely diagnosis is critical for effective treatment, yet it is often challenging due to the diverse clinical presentations. …”
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728
Obscure Gastrointestinal Bleeding from an Ampullary Tumour in a Patient with a Remote History of Renal Cell Carcinoma: A Diagnostic Conundrum
Published 1998-01-01“…Metastasis of renal cell carcinoma to the ampulla of Vater is a rare occurrence. …”
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729
Multiple Cutaneous Metastases as Initial Presentation in Advanced Colon Cancer
Published 2018-01-01“…Of all the tumors, breast cancer most commonly spreads as cutaneous metastasis is followed by lung, colorectal, renal, ovarian, and bladder cancers. …”
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730
Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5
Published 2014-03-01“…The EMT is believed to be an important step in metastasis and is implicated in cancer progression, although the influence of the EMT in clinical specimens has been debated. …”
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731
The Role of Pulmonary Metastasectomy in Breast Cancer with Limited Progression Following CDK4/6 Inhibitor Therapy: A Case Report
Published 2024-12-01“…Due to the progression of pulmonary metastasis following combined therapy with ribociclib and fulvestrant for advanced disease, she underwent PM, which histologically confirmed breast cancer metastasis. …”
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732
A Case Report of a Metastatic Gastrointestinal Stromal Tumor Occurring in Femur
Published 2011-01-01“…To the best of our knowledge, few cases have been reported in the literature about the femur metastasis of GIST. This paper describes a metastasis of a gastrointestinal stromal tumour (GIST) to the femur in a 62-year-old male, 2 years after treatment for a gastric primary. …”
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733
Epigenetics of cancer drug resistance
Published 2023-07-01“… One of the major causes due to cancer-related death is metastasis. The major factors contributing to metastasis of cancer cells are epithelial–mesenchymal transition and cancer stem cells. …”
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734
Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy
Published 2011-01-01“…Inflammatory pathways, meant to defend the organism against infection and injury, as a byproduct, can promote an environment which favors tumor growth and metastasis. Tumor-associated macrophages (TAMs), which constitute a significant part of the tumor-infiltrating immune cells, have been linked to the growth, angiogenesis, and metastasis of a variety of cancers, most likely through polarization of TAMs to the M2 (alternative) phenotype. …”
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735
Endoscopic Mucosal Resection for Esophageal and Gastric Mucosal Cancers
Published 1998-01-01“…In absolutely indicated cases there has been no local or distant metastasis during the longest period of follow-up (nine years). …”
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736
The Role of PPARs in the Endothelium: Implications for Cancer Therapy
Published 2008-01-01“…The growth and metastasis of cancers intimately involve the vasculature and in particular the endothelial cell layer. …”
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737
Metastatic Ureteral Involvement of Non-Small Cell Lung Cancer
Published 2011-01-01“…After excluding the presence of other primary tumors and metastases, we reached a final diagnosis of solitary retroperitoneal metastasis of adenocarcinoma of the lung. Although rare, in patients of non-small cell lung cancer, presence of hydronephrosis should alert the physician to the possibility of metastasis.…”
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738
Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases
Published 2025-01-01“…Natural killer (NK) cells can control metastasis through cytotoxicity and IFN-γ production independently of T cells in experimental metastasis mouse models. …”
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739
circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4
Published 2025-01-01“…A series of in vitro and in vivo functional experiments were performed to verify the effects of circASAP1 on RCC proliferation and metastasis. Results Circular RNA sequencing analysis revealed that circASAP1 expression was markedly elevated in ccRCC, with a significant association observed between elevated circASAP1 expression and poor prognosis and metastasis. …”
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740
RETRACTED ARTICLE: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Sna...
Published 2014-11-01“…However, the inhibition of the metastasis mechanism of COE in gastric cancer cells has not been investigated so far. …”
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