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  1. 721

    Cell Counts, rather than Proportion, of CD8/PD-1 Tumor-Infiltrating Lymphocytes in a Tumor Microenvironment Associated with Pathological Characteristics of Chinese Invasive Ductal... by Qingkun Song, Feng Shi, Maya Adair, Hong Chang, Xiudong Guan, Yanjie Zhao, Yuchen Li, Guangjiang Wu, Jiangping Wu

    Published 2019-01-01
    “…The proportion of CD8+/PD-1- TILs was 16% among patients with axillary lymph node metastasis, significantly lower than those without metastasis (24%). …”
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    Article
  2. 722

    miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5 by Jiahui Mao, Lingxia Wang, Junying Wu, Yichun Wang, Huiyan Wen, Xueming Zhu, Bo Wang, Huan Yang

    Published 2021-01-01
    “…Our results demonstrated that miR-370-3p significantly promoted proliferation, metastasis, and stemness of breast cancer in vitro and in vivo. …”
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    Article
  3. 723

    HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop by Qiaohui Gao, Zhenghua Ren, Shengyuan Jiao, Juan Guo, Xia Miao, Jin Wang, Junye Liu

    Published 2022-01-01
    “…Hypoxia has crucial functions in the development and metastasis of cervical cancer by inducing the expression of numerous genes, including microRNA genes. …”
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    Article
  4. 724

    The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review by Qi Zhao, Ying Ma, Zugui Li, Kexin Zhang, Minying Zheng, Shiwu Zhang

    Published 2020-01-01
    “…Malignant tumors still pose serious threats to human health due to their high morbidity and mortality. Recurrence and metastasis are the most important factors affecting patient prognosis. …”
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    Article
  5. 725

    Outcomes of Recurrent Head and Neck Cutaneous Squamous Cell Carcinoma by Nichole R. Dean, Larissa Sweeny, J. Scott Magnuson, William R. Carroll, Daniel Robinson, Renee A. Desmond, Eben L. Rosenthal

    Published 2011-01-01
    “…Distant metastasis was a strong indicator of poor overall survival (P<.001). …”
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    Article
  6. 726

    Unveiling the complex double-edged sword role of exosomes in nasopharyngeal carcinoma by Xueyan Huang, Yuedi Tang

    Published 2025-01-01
    “…Exosomes could serve as biomarkers and therapeutic agents, as well as the molecular mechanisms by which they promote cell growth, angiogenesis, metastasis, immunosuppression, radiation resistance, and chemotherapy resistance in NPC. …”
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    Article
  7. 727

    Primary leiomyosarcoma of the scalp: a case report and review of the literature by Shuo Gao, Pule Liu, Jixing Liu, Wenzhen Yang, Shude Yang

    Published 2025-02-01
    “…Background and importanceLeiomyosarcoma is a rare and aggressive malignant tumor with a high potential for relapse and metastasis. Correct and timely diagnosis is critical for effective treatment, yet it is often challenging due to the diverse clinical presentations. …”
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    Article
  8. 728
  9. 729

    Multiple Cutaneous Metastases as Initial Presentation in Advanced Colon Cancer by Sudheer Nambiar, Asha Karippot

    Published 2018-01-01
    “…Of all the tumors, breast cancer most commonly spreads as cutaneous metastasis is followed by lung, colorectal, renal, ovarian, and bladder cancers. …”
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    Article
  10. 730

    Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5 by Semi Kim, Jung Weon Lee

    Published 2014-03-01
    “…The EMT is believed to be an important step in metastasis and is implicated in cancer progression, although the influence of the EMT in clinical specimens has been debated. …”
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    Article
  11. 731

    The Role of Pulmonary Metastasectomy in Breast Cancer with Limited Progression Following CDK4/6 Inhibitor Therapy: A Case Report by Yu-Ting Su, Shang-Hung Chen

    Published 2024-12-01
    “…Due to the progression of pulmonary metastasis following combined therapy with ribociclib and fulvestrant for advanced disease, she underwent PM, which histologically confirmed breast cancer metastasis. …”
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    Article
  12. 732

    A Case Report of a Metastatic Gastrointestinal Stromal Tumor Occurring in Femur by Chang-kun Zheng, Wu-Sheng Kan, Peng Li

    Published 2011-01-01
    “…To the best of our knowledge, few cases have been reported in the literature about the femur metastasis of GIST. This paper describes a metastasis of a gastrointestinal stromal tumour (GIST) to the femur in a 62-year-old male, 2 years after treatment for a gastric primary. …”
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    Article
  13. 733

    Epigenetics of cancer drug resistance by Sayandeep Mukherjee, Ronit Dey, Subhabrata Guha, Nabendu Murmu, Gaurav Das

    Published 2023-07-01
    “… One of the major causes due to cancer-related death is metastasis. The major factors contributing to metastasis of cancer cells are epithelial–mesenchymal transition and cancer stem cells. …”
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    Article
  14. 734

    Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy by Marc Baay, Anja Brouwer, Patrick Pauwels, Marc Peeters, Filip Lardon

    Published 2011-01-01
    “…Inflammatory pathways, meant to defend the organism against infection and injury, as a byproduct, can promote an environment which favors tumor growth and metastasis. Tumor-associated macrophages (TAMs), which constitute a significant part of the tumor-infiltrating immune cells, have been linked to the growth, angiogenesis, and metastasis of a variety of cancers, most likely through polarization of TAMs to the M2 (alternative) phenotype. …”
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    Article
  15. 735

    Endoscopic Mucosal Resection for Esophageal and Gastric Mucosal Cancers by Haruhiro Inoue

    Published 1998-01-01
    “…In absolutely indicated cases there has been no local or distant metastasis during the longest period of follow-up (nine years). …”
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  16. 736

    The Role of PPARs in the Endothelium: Implications for Cancer Therapy by David Bishop-Bailey, Karen E. Swales

    Published 2008-01-01
    “…The growth and metastasis of cancers intimately involve the vasculature and in particular the endothelial cell layer. …”
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    Article
  17. 737

    Metastatic Ureteral Involvement of Non-Small Cell Lung Cancer by Koichi Kodama, Tetsuya Imao, Kazuto Komatsu

    Published 2011-01-01
    “…After excluding the presence of other primary tumors and metastases, we reached a final diagnosis of solitary retroperitoneal metastasis of adenocarcinoma of the lung. Although rare, in patients of non-small cell lung cancer, presence of hydronephrosis should alert the physician to the possibility of metastasis.…”
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  18. 738

    Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases by Shih-Wen Huang, Yein-Gei Lai, Hao-Ting Liao, Chin-Ling Chang, Ruo-Yu Ma, Yung-Hsiang Chen, Yae-Huei Liou, Zhen-Qi Wu, Yu-Chen Wu, Ko-Jiunn Liu, Yen-Tsung Huang, Jen-Lung Yang, Ming-Shen Dai, Nan-Shih Liao

    Published 2025-01-01
    “…Natural killer (NK) cells can control metastasis through cytotoxicity and IFN-γ production independently of T cells in experimental metastasis mouse models. …”
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    Article
  19. 739

    circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4 by Yunfei Wang, Taowei Yang, Qihao Li, Zhousan Zheng, Lican Liao, Junjie Cen, Wei Chen, Junhang Luo, Yi Xu, Mi Zhou, Jiaxing Zhang

    Published 2025-01-01
    “…A series of in vitro and in vivo functional experiments were performed to verify the effects of circASAP1 on RCC proliferation and metastasis. Results Circular RNA sequencing analysis revealed that circASAP1 expression was markedly elevated in ccRCC, with a significant association observed between elevated circASAP1 expression and poor prognosis and metastasis. …”
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  20. 740