Principles of diuretic therapy at liver cirrhosis by A. I. Dyadyk, T. Ye. Kugler, I. S. Malovichko, N. F. Yarovaya, I. V. Rakitskaya

“…The doctor should be aware of diuretic-related complications spectrum (hemodynamic, electrolytic, acid-base metabolism disorders) that will provide timely diagnostics and elimination and consequently, increase in treatment efficacy. …”
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A review on probiotics and dietary bioactives: Insights on metabolic well-being, gut microbiota, and inflammatory responses by Alice Njolke Mafe, Great Iruoghene Edo, Osamah S. Majeed, Tayser Sumer Gaaz, Patrick Othuke Akpoghelie, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Joseph Oghenewogaga Owheruo, Rapheal Ajiri Opiti, Yasal Garba, Arthur Efeoghene Athan Essaghah, Dina S. Ahmed, Huzaifa Umar

“…The paper investigates the mechanisms through which probiotics and bioactives, found in both traditional and contemporary foods, support gut health and combat metabolic disorders. It highlights the various types of probiotics in foods, their effects on immune function, and their role in regulating inflammatory response and metabolic well-being. …”
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The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model by Jan Dusek, Ivana Mejdrová, Klára Dohnalová, Tomas Smutny, Karel Chalupsky, Maria Krutakova, Josef Skoda, Azam Rashidian, Ivona Pavkova, Kryštof Škach, Jana Hricová, Michaela Chocholouskova, Lucie Smutna, Rajamanikkam Kamaraj, Miloš Hroch, Martin Leníček, Stanislav Mičuda, Dirk Pijnenburg, Rinie van Beuningen, Michal Holčapek, Libor Vítek, Magnus Ingelman-Sundberg, Oliver Burk, Thales Kronenberger, Radim Nencka, Petr Pavek

“…Such ligands hold the potential for precise modulation of liver metabolism, offering new therapeutic strategies for metabolic disorders.…”
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Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model by Shunan Wang, Ming Shen, Bo Pang, Bo Zhou, Yuan Yuan, Mei Lu, Xiangling Deng, Min Yang, Shufang Liu, Qiong Wang, Mei Xue, Qisheng Xia, Zhixin Zhang

“…Abstract Background Hyperphenylalaninemia, a prevalent amino acid metabolism disorder, often results in cognitive impairment. …”
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Untargeted metabolomic and proteomic analysis implicates SIRT2 as a novel therapeutic target for diabetic nephropathy by Ruijing Zhang, Runze Chang, Heng Wang, Jinshan Chen, Chuanlong Lu, Keyi Fan, Yuhang Zhang, Lizheng Li, Sheng Yan, Honglin Dong

“…In conclusion, our study combines metabolomics and proteomics to provide valuable insights into the synergistic roles of metabolic disorders and inflammatory responses in DN. The data suggest that SIRT2 may be a key target affecting these processes.…”
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Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism by L. V. Chesnokova, I. M. Petrov, Ye. A. Sidorova, I. A. Troshina, Yu. A. Petrova

“…Overall 67 patients with metabolic syndrome (MS) in combination to early carbohydrate metabolism disorders (71,6% women), mean age was 47,5 (42–49 years), body mass index — 34,6 kg/m2 (32,4–38,4 kg/m2) were investigated. …”
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Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease by O. Yu. Kytikova, T. P. Novgorodtseva, Yu. K. Denisenko, D. A. Kovalevsky

“…Progression of NAFLD and the development of NASH are closely related to lipid metabolism disorders caused not only by insufficient alimentary intake of fatty acids, but also by a decrease in the efficiency of their endogenous processing. …”
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Do NSAID/COX-2 Inhibitors Increase Nonunion After Fracture Surgery? Dilemma and Consideration In Use by Azmi

“…Several factors, including smoking, metabolic disorders, dietary inadequacy, and nonsteroidal anti-inflammatory drugs (NSAIDs), may predict nonunion development. …”
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Persistence of Olfactory Dysfunction in Post CoVid-19 Patients Using Sniffin Sticks-A Prospective Study by Priyanka Thangaraj, Sowmya Gajapathy, Jayita Das Poduval

“… INTRODUCTION This study is conducted to assess the Olfactory dysfunction (OD) of CoVid-19 recovered patients using ODOFIN Sniffin’ Sticks and to analyze the demographic features, duration of recovery, co-morbidities/metabolic disorders associated with persistence of OD in Post CoVid-19 patients. …”
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Hyperparathyroidism in Patients with End-Stage Chronic Liver Disease (Clinical Observations) by A. A. Lavreniuk, A. N. Gorbacheva, E. E. Bibik, A. K. Eremkina, I. N. Tikhonov, N. G. Mokrysheva

“…However, data on the development of mineral metabolism disorders, particularly hyperparathyroidism, in this population are very limited. …”
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Fecal Microbiota Transplantation: A Systematic Review of Therapeutic Potential, Preparation Techniques, and Delivery Methods Across Medical Conditions by Syamand Ahmed Qadir, Qausar Hamed ALKaisy, Abdulbasit F. Hasan, Farhang Hameed Awlqadr, Ammar B. Altemimi, Aryan Mahmood Faraj, Angelo Maria Giuffrè, Mohammed N. Saeed, Sherzad Rasul Abdalla

“…FMT’s applications are expanding to inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, as well as metabolic disorders and neuropsychiatric conditions. Remission rates for IBD range from 37-45%, with outcomes influenced by donor characteristics, stool preparation, and disease subtype.  …”
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Efficacy of ileostomy in Crohn's disease of the large intestine with perianal involvement by Yu. A. Shelygin, V. N. Kashnikov, K. V. Bolikhov, A. V. Vardanyan, I. L. Khalif

“…At total involvement of the large intestine in combination to two and more types of the perianal lesions along with severe metabolic disorders, ileostomy should be applied as the first-line surgical treatment.…”
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Caveolin Gene, a Possible Risk Factor for Metabolic Syndrome in Humans: A Systematic Review and Meta-Analysis by Mohadeseh Arefian, Sadegh Mazaheri-Tehrani, Maryam Yazdi, Roya Kelishadi

“…Background: Studies show that caveolin genes are associated with metabolic disorders, so we aimed to systematically review the association between caveolin genes and metabolic syndrome in human studies. …”
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Disorders of Adipose Tissue and Lipodystrophies: Causes, Consequences, and Treatment Perspectives by Rosińska Kamila Rosińska, Ewelina Justyna Janicka, Julia Natalia Skibicka, Monika Niedźwiedzka, Mateusz Rosiński

“… Lipodystrophies are rare metabolic disorders characterized by the loss of adipose tissue, which can manifest as generalized, partial, or localized. …”
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A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods by Yajun Qiao, Yajun Qiao, Yajun Qiao, Juan Guo, Qi Xiao, Jianv Wang, Jianv Wang, Xingfang Zhang, Xingfang Zhang, Xinxin Liang, Xinxin Liang, Lixin Wei, Lixin Wei, Hongtao Bi, Tingting Gao, Tingting Gao

“…In summary, female mice have stronger stress sensitivity and weaker resilience than male mice, which may be related to differences in bacterial diversity and estrogen metabolism disorders.…”
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Hepatocellular carcinoma: signaling pathways and therapeutic advances by Jiaojiao Zheng, Siying Wang, Lei Xia, Zhen Sun, Kui Ming Chan, René Bernards, Wenxin Qin, Jinhong Chen, Qiang Xia, Haojie Jin

“…Hepatocellular carcinoma (HCC) constitutes around 90% of liver cancer cases and is primarily linked to factors incluidng aflatoxin, hepatitis B (HBV) and C (HCV), and metabolic disorders. There are no obvious symptoms in the early stage of HCC, which often leads to delays in diagnosis. …”
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Functional effects of operations for malignant gastric neoplasms: prevention, diagnosis and treatment of post-gastrectomy disorders by A. V. Chaika, V. M. Khomyakov, A. B. Ryabov

“…Three basic groups of disorders are defined: disorders related to impaired organ anatomy; disorders caused by change in anatomical and physiological interrelations and developing as a compensatory response (mostly of functional origin); metabolic disorders. Development of inflammatory and of fibrotic anastomotic strictures and stenoses, erosions and/or ulcers, as well as obstruction caused by intestinal loop in relation or peritoneal adhesions make conservative treatment ineffective that require endoscopic or open surgical approaches: bougieurage, stenting or surgical reconstruction. …”
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Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis by Xiaoxue Wang, Longhao Cheng, Aijun Liu, Lihong Liu, Lili Gong, Guolin Shen

“…To better understand metabolic disorders and expand the potential targets for MM, we conducted large-scale untargeted metabolomics on plasma samples from MM patients and healthy controls (HC). …”
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Higher gut Bacteroidetes and Actinobacteria population in early pregnancy is associated with lower risk of gestational diabetes in the second trimester by Seyedeh Neda Mousavi, Navid Momeni, Hossein Chiti, Howra Mahmoodnasab, Mohammad Ahmadi, Siamak Heidarzadeh

“…Abstract Background Despite the association between the gut dysbiosis and metabolic disorders, the main bacterial phylum in the first trimester of pregnancy that predisposes mothers to gestational diabetes mellitus (GDM) in the second trimester is not clear around the world. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…In addition, we found the metabolic disorders induced by NEOs were linked to the deterioration of BAT thermogenesis in vivo. …”
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