An optimized data analytics pipeline for improving healthcare diagnosis using ensemble learning by Lomat Haider Chowdhury, Shaira Tabassum, Swakkhar Shatabda, Ashir Ahmed

“…Healthcare diagnosis is a process physicians follow before prescribing the patients. The medical doctors may make an early prediction by observing the physical signs and symptoms. …”
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Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

“…Xiaoxia Ding,1,* Zicheng Bai,2,* Wenwen Wang,2 Yu Gu,3 Zhiming Li,2 Yibin Fan1 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Dermatology and Venereology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Dermatology, The First People’s Hospital of Aksu Prefecture, Aksu, XinJiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yibin Fan, Email fanyibin@hmc.edu.cn; Zhiming Li, Email zhi-mingli@wmu.edu.comBackground: Prior studies have suggested a significant connection between fasting insulin (FI) and androgenetic alopecia (AGA), but the exact cause of this connection and underlying molecular mechanism has not been clarified. …”
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High Healthcare Utilization in Adolescents with Sickle Cell Disease Prior to Transition to Adult Care: A Retrospective Study by Julie Kanter, Menaka Bhor, Xin Li, Frank Li, Jincy Paulose

“…Pulmonary disease (31.1%, n=369) was the most frequent complication; blood transfusions (mean: 8.4 [SD:7.0]) and iron-chelating therapies (mean: 8.6 [SD:10]) were the most common interventions and medications, respectively. In the 16 to 18 year old group, patients with SCD had 2.0 (SD = 2.3) hospital admissions, 3.4 (SD = 4.0) ER visits, and 5.0 (SD = 4.2) office visits. …”
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Comparison of Learning Curves and Clinical Outcomes in Unilateral Biportal Endoscopic Spinal Surgery Versus Percutaneous Transforaminal Endoscopic Surgery: A Cumulative Sum Analysi... by Yuan S, Chen R, Mei Y, Fan N, Wang T, Wang A, Du P, Xi Y, Zang L

“…Shuo Yuan,* Ruiyuan Chen,* Yuqi Mei,* Ning Fan, Tianyi Wang, Aobo Wang, Peng Du, Yu Xi, Lei Zang Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lei Zang, Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, 5 JingYuan Road, Shijingshan District, Beijing, 100043, People’s Republic of China, Tel +86-10-51718268, Email zanglei@ccmu.edu.cnPurpose: Endoscopic spine surgery has been widely performed to treat degenerative spinal diseases to mitigate the risks and complications associated with traditional open surgery. …”
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Exploring drug utilization patterns, healthcare resource utilization, and epidemiology of rheumatoid arthritis in Colombia: a retrospective claims database study by Daniel G. Fernández-Ávila, Monica Betancur, Amira Kronfly, Edwin Jáuregui

“…The proportion of patients prescribed targeted synthetic DMARDs increased from 0.9% in 2017 to 1.8% in 2021. The rate of medical consultations increased over the study period (from 2,406.6 in 2017 to 3,354.2 per 1,000 patients with RA in 2022). …”
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Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine by Farhang H. Awlqadr, Kithar Rasheed Majeed, Ammar B. Altemimi, Arkan Mohammed Hassan, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Alaa Jabbar Abd Al‐Manhel, Mazin A.A. Najm, Efstathia Tsakali, Jan F.M. Van Impe, Ahmed A. Abd El-Maksoud, Tarek Gamal Abedelmaksoud

“…This review deals with nano-herbal formulations' preparation, applications, and therapeutic capabilities for medical problems and foods like food packaging and preservation. …”
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Evaluation of three novel antigens and costimulatory agents for improvement of M. Tuberculosis specific interferon gamma release assays by Sandra Schwarzlose-Schwarck, Mark Reinwald, Torsten Bauer, Florian Hentschel, Til Kiderlen, Dorinja Zapf, Victor Herbst, Stefan Lüth, David Krieger, Werner Dammermann

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Intrathecal Clonidine versus Dexmedetomidine as Adjuvants to Hyperbaric Ropivacaine in Lower Limb Orthopaedic Surgeries: A Randomised Clinical Study by Priya Kishnani, Aiman Monaf, Kalpesh Pati, Jatin Patel, Sara Mary Thomas

“…Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (SBKS and MIRC), Piparia, Waghodia, Vadodara, Gujarat, India. …”
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Single-nucleotide polymorphisms in dizygotic twin ovine fetuses are associated with discordant responses to antenatal steroid therapy by Erin L. Fee, Haruo Usuda, Sean W. D. Carter, Hideyuki Ikeda, Tsukasa Takahashi, Yuki Takahashi, Yusaku Kumagai, Michael W. Clarke, Demelza J. Ireland, John P. Newnham, Masatoshi Saito, Sebastian E. Illanes, Binny Priya Sesurajan, Liang Shen, Mahesh A. Choolani, Gokce Oguz, Adaikalavan Ramasamy, Sara Ritchie, Andrew Ritchie, Alan H. Jobe, Matthew W. Kemp

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Risk factors associated with degenerative glenohumeral osteoarthritis by Ravi Prakash, Nitin B Jain, Ziyi Chen, Folefac D Atem, Michael S Khazzam, Rashmi Pathak, Daniel Tai, Ursa BezanPetric, Estefanie Garduno Rapp

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Administration of Sex Hormone Preparations as a Risk Factor in the Development of Intrahepatic Cholestasis of Pregnancy and Biliary Sludge in Pregnant Women by Yu. B. Uspenskaya, I. V. Kuznetsova, A. A. Sheptulin, N. V. Goncharenko, A. N. Gerasimov, M. M. Amiraslanova

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Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women und... by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

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Enhancing deep learning methods for brain metastasis detection through cross-technique annotations on SPACE MRI by Tassilo Wald, Benjamin Hamm, Julius C. Holzschuh, Rami El Shafie, Andreas Kudak, Balint Kovacs, Irada Pflüger, Bastian von Nettelbladt, Constantin Ulrich, Michael Anton Baumgartner, Philipp Vollmuth, Jürgen Debus, Klaus H. Maier-Hein, Thomas Welzel

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PLGA-based biocompatible nanoparticles improved anti-breast tumor efficacy of 1,25(OH)2D3 through the SOCS3/STAT3/EMT signaling axis by JinJing Pan, Ping Wang, Linghong Xiong, Wenqing Yang, Jie Li, Kai Yang, Bingyan Li

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Impact of Nutritional Support for Tuberculosis on Intermediate and Terminal Undernutrition and Treatment Outcomes (INSTITUT) study: a protocol for a quasi-experimental study to ass... by Dissou Affolabi, Chelsie Cintron, Madolyn Dauphinais, Attannon Arnauld Fiogbe, Mohammed Fall Dogo, Safiou Ate, Christine Adjonou, Kokou Agossou, Susie Jiaxing Pan, Marius Esse, Benjamin Ade, Komi Séraphin Adjoh, Pranay Sinha, Kobto G Koura

“…We hypothesise that participants receiving nutritional support will experience fewer unfavourable outcomes, faster sputum clearance, improved weight gain and fewer persistent respiratory symptoms.Ethics and dissemination This study has received approval from the Boston University Medical Campus and Boston Medical Center Institutional Review Board (H-43096). …”
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Prognosis of erosions development at gastric metaplasia of esophageal mucosa in patients with gastroesophageal reflux disease by Ye. K. Mastykova, M. R. Konorev, M. E. Matveyenko

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Polymorphism of genes and drug-induced liver injury by P. Ye. Tkachenko, M. V. Mayevskaya, V. T. Ivashkin

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Clinical Usefulness of Atrioventricular Coupling in Cardiovascular Disease by Yang Lan, Li Zhenyi, Chen Ya, Chen Anni, Wang Xinqi, Jin Lin, Li Zhaojun

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Modeling critical dosing strategies for stromal-induced resistance to cancer therapy by Anna K. Kraut, Colleen M. Garvey, Carly Strelez, Shannon M. Mumenthaler, Jasmine Foo

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