Temporal trends in guideline-recommended medical therapy after an acute heart failure decompensation event: an observational analysis from Generator Heart Failure DataMart by Antonio Gasbarrini, Giuseppe Patti, Filippo Crea, Giovanni Scambia, Domenico D'Amario, Vincenzo Valentini, Gianluigi Savarese, Alfredo Cesario, Jacopo Lenkowicz, Stefano Patarnello, Renzo Laborante, Agni Delvinioti, Andrada Mihaela Tudor, Chiara Iacomini, Antonio Iaconelli, Donato Antonio Paglianiti, Mattia Galli, Daniele Rodolico, Attilio Restivo, Giuseppe Ciliberti, Gaetano Rizzo, Emiliano Bianchini, Matteo Busti, Luca Sensini

“…Conversely, the prescription of furosemide at discharge (adjusted OR 2.25; 95% CI 95% 1.29 to 3.94; p<0.01) and a previous genitourinary infection (adjusted OR 4.02; 95% CI 1.67 to 9.68; p<0.01) were associated with higher risk of 30-day all-cause death and urgent rehospitalisation.Conclusions In our study, early adoption of guideline-recommended medical therapy is still limited, with a significant rise in SGLT2i prescriptions after January 2022 and a lower risk of the composite of all-cause death and urgent readmissions at 30 days restricted to the use of ACEi/ARB/ARNi.…”
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The Impact of Recent Generic Drug Price Policies on Pharmaceutical Innovation: A Theoretical Rationale and Proposal of a Method Supporting Innovation in Areas of Unmet Medical Need by Pierre-Alexandre Dionne, Farzad Ali, Mendel Grobler

“…In order to promote innovation in therapeutic fields with unmet medical needs, a compromise would be to include the comparator’s patented price in the CEA instead of the generic drug. …”
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Uptake of voluntary medical male circumcision among men with sexually transmitted infections in Lilongwe, Malawi: a protocol for a pre-interventional and post-interventional study by Mina C Hosseinipour, Mitch M Matoga, Sara Jewett, Charles Chasela

“…Introduction Voluntary medical male circumcision (VMMC) is one of the key interventions for HIV prevention. …”
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Temporal trends of the utilization patterns of sedative-hypnotic medications in children, adolescents and young adults: a 21-year population-based study with joinpoint regression analysis by Carltin Chun Ting Kwok, Heidi Ka Ying Lo, Ching Yui Chan, Joe Kwun Nam Chan, Corine Sau Man Wong, Calvin Pak Wing Cheng, Chung Ho, Brian Man Ho Leung, Wilfred Shone Horn Wong, Zoe Hoi Shuen Yu, Edwin Ho Ming Lee, Wing Chung Chang

“…Methods This population-based study identified 60,660 individuals aged 4–24 years who had redeemed ≥ 1 BZRA prescription within 2000–2020, using data from medical-record database of Hong Kong public-healthcare-services. …”
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Introducing 3D printed models of fractures in osteology learning improves clinical reasoning skills among first-year medical students: a pilot study by Abhishek Agarwal, Anne D Souza, B. Jyostna, Ashwija Shetty, Nandini Bhat

“…BMC Medical Education…”
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Integrating Tradition and Modernity: The Gharana System for Effective Mentorship at GAIMS by Ajeet Kumar Khilnani

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Treatment of convulsive status epilepticus in Brazil: a review by Luis Otavio Caboclo

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Resolution of Symposium on scientific medical communication «The issue of GERD with discussion of potential of GerdQ questionnaire as additional tool for GERD diagnostics in clinician’s practice» of 26 June 2013 by article Editorial

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Assessment of caries diagnostic threshold of DMFT, and ICDAS II in the estimation of caries prevalence rate in first permanent molars among students of College of Dentistry-Hawler Medical University. by Razawa Kareem Saeed, Mustafa Isa Omer, Neenor Nazar Hanna, Hallo Khals Ghafour

“…Method: This study was carried out among the students of Hawler medical university/college of dentistry. The total number of samples was (100) samples. …”
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Evaluation of root development of mandibular first molar of children (6-12) years old visiting P.O.P. department College of Dentistry/ Hawler Medical University. by Yara Ismail Ameen, Manal Muhammed Taher, Mahmood Fawzi Abduljabar

“…Method: Dentists in the Paediatric dentistry Department at Hawler Medical University saw all the children in the sample, and they were all in good health condition. …”
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A study on awareness regarding cigarettes and other tobacco products act (COTPA Act) among hospital staff of medical college, Kanpur: A mixed method study by Aradhana Yadav, Sonam, Samarjeet Kaur, Santosh K. Barman, Seema Barman

“…Settings and Design: This study was conducted in GSVM Medical College, and this was a convergent parallel mixed-methods study, with a quantitative component (cross-sectional survey) complemented by a qualitative component (descriptive study). …”
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Effects of Pimobendan on Prolonging Time to Rehospitalization or Frequency of Rehospitalization in Patients with Heart Failure: A Retrospective Cohort Study Using a Medical Administrative Database (PREFER Study) by Kazuhisa Kodama, Tatsunori Murata, Naoki Dohi, Masaaki Nakano, Toshiaki Yokoi, Tomohiro Sakamoto, Koichi Nakao

“…**Objective:** The objective of this study was to investigate the influence of pimobendan on rehospitalization of patients with advanced heart failure using a Japanese medical administrative database. **Methods:** From January 2010 to February 2018, patients hospitalized two or more times for heart failure were selected for analysis. …”
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The role of Pharmaceutical Marketing in Prescribing Decisions in a Developing Country: A Comprehensive Study Exploiting Theory of Planned Behaviour by Mahmoud Al-Areefi, Mohamed Izham Mohamed Ibrahim, Abubakr Abdelraouf Alfadl

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Voices of change: experiences of early women urology residents — a single institution qualitative research study by Aurora J. Grutman

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Associated Factors of the Need for Mechanical Ventilation Following Traumatic Injuries; a Registry-Based Study on 2,708 Cases in Iran by Zahra Ramezani, Vali Baigi, Mohammadreza Zafarghandi, Vafa Rahimi-Movaghar, Reza Farahmand-Rad, Akram Zolfaghari Sadrabad, Seyed-Mohammad Piri, Mahgol Sadat Hassan Zadeh Tabatabaei, Khatereh Naghdi, Payman Salamati

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Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation by A. D. Kaprin, N. S. Sergeeva, S. S. Pirogov, I. I. Alentov, O. К. Yutsevich, V. I. Ryabtseva, G. F. Minibaeva, N. V. Marshutina, T. А. Karmakova

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