Terlipressin at esophageal varicose bleeding at liver cirrhosis with portal hypertension syndrome by B. N. Kotiv, I. I. Dzidzava, D. P. Kashkin, A. V. Smorodsky, A. V. Slobodyanik, S. A. Soldatov, M. V. Koldin

“…After injection of octreotide decrease of main velocity features of portal blood flow was marked as well: linear speed has decreased by 34,1±10,3% (р=0,030), and volume – by 28,6±9,8% (р=0,041). …”
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Sources, Compositions, and Health Risks of PM2.5-bound PAHs at the Rural Area along with the “Coal to Gas” Law by Zhiyong Li, Ziyuan Yue, Wenjia Zhu, Wenquan Liu, Jintao Gao, Jiaqiang Zhang, Ziyi Zhan, Lan Chen, Huiying Gao, Jihong Wei

“…Abstract The “Coal to Gas” (CTG) policy in north China markedly altered the characteristics of polycyclic aromatic hydrocarbons (PAHs) in PM2.5. …”
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Super-twisting sliding mode control of grid-side inverters for wind power generation systems with parameter perturbation by Weiqi Zhang, Yanmin Wang, Muhammad Zeeshan, Fengling Han, Kai Song

“…The results indicate that the proposed method markedly enhances the active/reactive power response and stability of three-phase voltage/current signals under parameter perturbations, attaining a rapid consensus convergence response time of 1.5 ms for power deviations below 4.92 %, with output voltage and current harmonic content reduced by 0.27 % and 5.62 %, respectively, compared to PI control.…”
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Visual, clinical and quality of life outcomes of a new multifocal IOL with optimized diffractive grating: a non-randomized clinical trial by João Marcelo de Almeida Gusmão Lyra, Mariana Silva Gois de Almeida, Lucila de Albuquerque Barbosa Lira, Laís Oliveira dos Santos, Mateus Lins dos Santos, Jorge Artur Peçanha de Miranda Coelho

“…Quality of life, as assessed by the NEI-VFQ 25, showed marked improvement across all domains (p < 0.05), with no significant complications directly attributable to the IOL. …”
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CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1–CXCR2 induced NETs by Yu Liang, Shuang Chen, Zhi Chen, Fang Peng, Qianwen Liu, Gan Xiong, Caihua Zhang, Maosheng Cheng, Rongsong Ling, Demeng Chen, Qimin Zhou

“…In addition, we conducted single-cell RNA sequencing analysis to examine the alterations in tumor microenvironment following CD276 depletion.Results In this study, we elucidate that CD276 is markedly upregulated in ESCC, correlating with poor prognosis. …”
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TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…Notably, HK2 levels were markedly higher in pancreatic cancer tissues compared to adjacent normal tissues. …”
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Association between echocardiographic parameters of cardiac structure and function and mild cognitive impairment by Kai Zhang, Xiaoxia Liu, Siyu Huang, Xinrui Liu, Meiqi Zhao, Chao Xue, Shijun Xia, Jianzeng Dong, Yu Kong, Changsheng Ma

“…Abstract Background Cardiovascular diseases (CVDs) marked with cardiac morphological or hemodynamical abnormalities are associated with mild cognitive impairment (MCI). …”
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Escherichia coli combination with PD-1 blockade synergistically enhances immunotherapy in glioblastoma multiforme by regulating the immune cells by Guochen Li, Haiyan Yang, Tengfei Ke, Na Tan, Xiaolan Du, Xirui Duan, Xinyan Zhou, Guangrong Zheng, Chengde Liao

“…Immunofluorescence staining and flow cytometry results demonstrated that the combination treatment group exhibited a significant upregulation of cytotoxic CD8+ T cells and a marked suppression of regulatory T cells compared to the control group. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

“…Inhibition of S100A8/A9 effectively attenuated NET-mediated neuroinflammation; however, when PAD4 was overexpressed in the brain using adenovirus, leading to an increased formation of NET in the brain, the anti-inflammatory effects of S100A8/A9 inhibition were markedly diminished. Further experiments with PAD4 knockout mice confirmed that the reduction of NETs could substantially alleviate S100A8/A9-driven neuroinflammation. …”
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CAR T-cell detection scoping review: an essential biomarker in critical need of standardization by Naomi Taylor, Nirali N Shah, David P Turicek, Victoria M Giordani, Josquin Moraly

“…Detection time points and the number of evaluated time points also ranged markedly and quantitative data were often not reported. …”
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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

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Epidemiological Changes in Hospitalized Bronchiolitis in Children Under 2 Years of Age in Hangzhou Before and After COVID-19 Restriction Easing by Xu X, Chen X, He J, Su L, Tong X, Sun Y, Huang S, Bai G, Chen Z

“…However, the epidemic trend of HRV presented no significant changes between 2022 and 2023.Conclusion: The findings suggest that bronchiolitis hospitalizations increased markedly after COVID-19 restriction easing, particularly among children aged 12– 18 months. …”
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Realist inquiry into Maternity care @ a Distance (ARM@DA): realist review protocol by Andrew Booth, Catrin Evans, Stephen Timmons, Helen Spiby, Mark Clowes, Nia Jones, Kerry Evans, Benash Nazmeen, Candice Sunney, Georgia Clancy

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Tectonometamorphic evolution of a subduction plate interface at the base of the Mirdita Ophiolite (Bajram Curri, northeastern Albania) by Madeline Richter, Kilian Pollok, Kujtim Onuzi, Kamil Ustaszewski

“…Corresponding microstructures indicate mineral growth at isotropic stresses, suggesting that deformation migrated into structurally lower, frontally accreted non-metamorphic units of the sub-ophiolitic mélange marking the start of obduction onto the passive Adriatic margin. …”
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Lung transplantation for pulmonary chronic graft-versus-host disease: a missed opportunity? by Andrea Zajacova, MD, Hélène Schoemans, MD, PhD, Mark Greer, MD, MRCP, Hildegard Greinix, MD, Peter Jaksch, MD, Osnat Shtraichman, MD, Rayid Abdulqawi, MD, PhD, Are M. Holm, MD, PhD, Robin Vos, MD, PhD, Saskia Bos, MD, PhD

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Return to play following craniotomy for non-traumatic brain lesions by Jovanna A. Tracz, Matthew L. Farmer, Mark Hughes, Debraj Mukherjee, Paul M. Brennan

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Exploration of treatment burden through examination of workload and patient capacity during transition onto kidney replacement therapy: a systematic review of qualitative research by Catrin Jones, Ross Cairns, Heather Walker, Silje Welsh, Benjamin Edgar, Karen Stevenson, Bhautesh D. Jani, Patrick B. Mark, David Kingsmore, Katie I. Gallacher

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Validation of Mortality Data Sources Compared to the National Death Index in the Healthcare Integrated Research Database by Jamal-Allial A, Sponholtz T, Vojjala SK, Paullin M, Papazian A, Eshete B, Mahmoudpour SH, Verpillat P, Beachler DC

“…Aziza Jamal-Allial,1 Todd Sponholtz,1 Shiva K Vojjala,2 Mark Paullin,2 Anahit Papazian,1 Biruk Eshete,2 Seyed Hamidreza Mahmoudpour,3 Patrice Verpillat,3 Daniel C Beachler2 1Safety & Epidemiology, Carelon Research, Newton, MA, USA; 2Safety & Epidemiology, Carelon Research, Wilmington, DE, USA; 3Merck Healthcare KGaA, Darmstadt, GermanyCorrespondence: Daniel C Beachler, Carelon Research, 123 Justison Street, Suite 200, Wilmington, DE, 19801, USA, Email Daniel.beachler@carelon.comBackground: The National Death Index (NDI) is the gold standard for mortality data in the United States (US) but has a time lag and can be operationally intensive. …”
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Peripheral Nerve Blocks Are Associated With Decreased Early Medical Complications, Dislocations, and Opioid Consumption Following Total Hip Arthroplasty by Brian P. McCormick, MD, Sean B. Sequeira, MD, Mark D. Hasenauer, MD, Robert P. McKinstry, MD, Frank R. Ebert, MD, Henry R. Boucher, MD

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On-Site Evaluation and Improvement Strategies of Radiation Occupational Hazard Prevention and Control Effectiveness in Medical Institution Construction Projects by Xie HX, Zhang MQ, Li ZX, Zhao HL

“…Compared to earlier evaluation periods (eg, before the implementation of new DR performance testing standards, where compliance rates were below 60%), there has been a marked improvement in compliance with performance and protection testing, particularly after the introduction of updated evaluation criteria. …”
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