Dire ce qui n’est pas encore là. Le statut logique de l’usage dans les énoncés de conception architecturale by Louis Vitalis

“…The use would thus be simulated by speech acts mimicking normal assertions in the manner of fictional speech. But the pragmatics of design also suggests some distinctions from fiction, notably in its aim of reality. …”
Get full text

Throughput-Optimal Scheduling for Cooperative Communications in Wireless Ad Hoc Networks by Thong Huynh, Won-Joo Hwang, Suk-Hwan Lee

“…In addition, we derive a simple and lightweight framework to implement the proposed policy in distributed manner. The simulation results show that the proposed scheduling policy outperforms the noncooperative policy and multihop relay policy.…”
Get full text

Neurturin Evokes MAPK-Dependent Upregulation of Egr4 and KCC2 in Developing Neurons by Anastasia Ludwig, Pavel Uvarov, Christophe Pellegrino, Judith Thomas-Crusells, Sebastian Schuchmann, Mart Saarma, Matti S. Airaksinen, Claudio Rivera

“…Here we demonstrate that the trophic factor neurturin can also trigger Egr4 expression and upregulate KCC2 in an ERK1/2-dependent manner. These results show that Egr4 is an important component in the mechanism for trophic factor-mediated upregulation of KCC2 in immature neurons involving the activation of specific intracellular pathways common to BDNF and Neurturin.…”
Get full text

Understanding the Mechanisms of Recovery and/or Compensation following Injury by Michael J. Hylin, Abigail L. Kerr, Ryan Holden

“…Research suggests that these changes correspond to each other in a bidirectional manner. Mechanisms surrounding phenomena like neural plasticity may offer an opportunity to explain how variables such as experience can impact improvement and influence the definition of recovery. …”
Get full text

Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination by Mathias Vormehr, Barbara Schrörs, Sebastian Boegel, Martin Löwer, Özlem Türeci, Ugur Sahin

“…Preclinical and early clinical data suggest that synthetic mRNA can serve as potent drug format allowing the cost efficient production of highly efficient vaccines in a timely manner. In this review, we describe a process, which integrates next generation sequencing based cancer mutanome mapping, in silico target selection and prioritization approaches, and mRNA vaccine manufacturing and delivery into a process we refer to as MERIT (mutanome engineered RNA immunotherapy).…”
Get full text

Sound Radiation due to Modal Vibrations of a Spherical Source in an Acoustic Quarterspace by Seyyed M. Hasheminejad, Mahdi Azarpeyvand

“…Radiation of sound from a spherical source, vibrating with an arbitrary, axisymmetric, time-harmonic surface velocity, while positioned within an acoustic quarterspace is analyzed in an exact manner. The formulation utilizes the appropriate wave field expansions along with the translational addition theorem for spherical wave functions in combination with the classical method of images to develop a closed-form solution in form of infinite series. …”
Get full text

Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy by Trond Lamark, Terje Johansen

“…Some proteins aggregate in a regulated manner required for different vital functional processes in the cells whereas other protein aggregates result from misfolding caused by various stressors. …”
Get full text

A model-independent compact dynamical system formulation for exploring bounce and cyclic cosmological evolutions in $$f\, (R)$$ f ( R ) gravity by Saikat Chakraborty, Charlotte Louw, A. S. Agrawal, Peter K. S. Dunsby

“…In particular, our analysis reveals, in a model-independent manner, the problem of achieving such cosmologies when the universe is globally spatially flat and devoid of matter.…”
Get full text

Adverse Immunologically Mediated Oral Mucosal Reactions to Systemic Medication: Lichenoid Tissue Reaction/Interface Dermatitis-Stomatitis, Autoimmune Vesiculobullous Disease, and I... by R. A. G. Khammissa, R. Chandran, A. Masilana, J. Lemmer, L. Feller

“…The type of hypersensitivity immune response generated, whether antibody mediated or T cell mediated, or an immune complex reaction is determined by multiple factors, including the molecular characteristics of the allergen, the route of administration of the medication, the manner of presentation of the allergen by antigen-presenting cells to naïve T cells, the repertoire of the T cell receptors, and the cytokine profile within the microenvironment. …”
Get full text

The CLiGS Textbox: Building and Using Collections of Literary Texts in Romance Languages Encoded in TEI XML by Christof Schöch, José Calvo Tello, Ulrike Henny-Krahmer, Stefanie Popp

“…We describe the rationale for the manner in which the collections of literary texts included in the textbox have been compiled, annotated, and published. …”
Get full text

Enhancing Existing Communication Services with Context Awareness by Bachir Chihani, Emmanuel Bertin, Irsalina Salsabila Suprapto, Julien Zimmermann, Noël Crespi

“…If extensive studies have been driven on context awareness by industrials and researchers from academia, the design of such systems without modifying uses and manners of underlying communication services—while keeping them simple, intuitive, and reactive—remains a challenge. …”
Get full text

Effect of rutin from tartary buckwheat sprout on serum glucose-lowering in animal model of type 2 diabetes by Lee Dong-Gi, Jang Ik Soon, Yang Kyeong Eun, Yoon So-Jung, Baek Sujeong, Lee Joo Yong, Suzuki Tatsuro, Chung Keun-Yook, Woo Sun-Hee, Choi Jong-Soon

“…Rutin down-regulated the expression levels of protein-tyrosine phosphatase 1B; it is negative regulator of insulin pathway, both transcriptionally and translationally in myocyte C2C12 in a dose-dependent manner. In conclusion, rutin can play a critical role in down-regulation of serum glucose level in type 2 diabetes.…”
Get full text

Comprehensive Management of Ectodermal Dysplasia with Interceptive Orthodontics in a Young Boy Who Was Bullied at School by A. A. A. K. Wimalarathna, W. B. M. C. R. D. Weerasekara, E. M. U. C. K. Herath

“…An 11-year-old boy with ED was treated and managed by means of interceptive orthodontic treatment accompanied by direct and indirect restorative methods in a successful manner. The patient was prepared to receive definitive oral rehabilitation with dental implants for the missing teeth when the patient reaches a suitable age. …”
Get full text

Multi-omics unveils strain-specific neuroactive metabolite production linked to inflammation modulation by Bacteroides and their extracellular vesicles by Basit Yousuf, Walid Mottawea, Galal Ali Esmail, Nazila Nazemof, Nour Elhouda Bouhlel, Emmanuel Njoku, Yingxi Li, Xu Zhang, Zoran Minic, Riadh Hammami

“…Using untargeted and targeted metabolomics, we identified key neurotransmitter-related or precursor metabolites, including GABA, l-tryptophan, 5-HTP, normelatonin, kynurenic acid, l-tyrosine, and norepinephrine, in a strain- and media-specific manner, with GABA (1–2 mM) being the most abundant. …”
Get full text

Zmartwychwstanie przez technikę. Problem tożsamości umysłu w koncepcjach rozwoju sztucznej inteligencji. by Olgierd Sroczyński

“…In contemporary popular concepts concerning the development of artificial intelligence, it is assumed that if a program/model provides answers or operates in a manner similar to humans, then it can be considered to have achieved human-level capability. …”
Get full text

Representation of Traumatic Memory in the Film Drishyam: A Barthesian Reading by Srilekha B. P., V. Bharathi Harishankar

“…Its portrayal of diverse emotions and themes often mirrors societal events in a realistic and compelling manner. Enhanced by various cinematographic techniques, the depiction of trauma is magnified within the visual narrative. …”
Get full text

Travailler sur des objets en faisant se confronter les points de vue. Regards croisés sur le langage fou : l’exemple des écrits bruts by Vincent Capt

“…These points of view are then related to the theme of madness, using the notional couple "mania/manner" as a starting point. The specific historicity of the works related to art brut (particularly the written texts that initially came from psychiatric institutions) is thus examined in detail: going from a symptomatology of madness to a poetics of madness, it activated a theory of language and enabled society as a whole to be interpreted.…”
Get full text

An Aggregating Prediction Model for Management Decision Analysis by Jianhong Guo, Che-Jung Chang, Yingyi Huang, Xiaotian Zhang

“…Facing an increasingly competitive market, enterprises need correct decisions to solve operational problems in a timely manner to maintain their competitive advantages. In this context, insufficient information may lead to an overfitting phenomenon in general mathematical modeling methods, making it difficult to ensure good analytical performance. …”
Get full text

De la poésie au collage, du cinéma au graffiti by Sophie Dannenmüller

“…In the Verifax Collages (1964-1976), letters and signs disturb the linear reading of the grids of images placed in the manner of comic strips to depict the contemporary period. …”
Get full text

Philippians 4:10-23 from a rhetorical perspective by A. H. Snyman

“…In analysing the rhetorical strategies and techniques in 4:10-23, the focus is on the manner in which Paul argues, the type of arguments he uses and the rhetorical techniques that could enhance the impact of his communication. …”
Get full text