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16101
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16102
T Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Bone Loss via CD39 and CD73-Mediated ATP Hydrolysis
Published 2025-01-01“…Xiaoshan Yang,1– 3,* Yang Zhou,2,3,* Fuxing Zhou,4,* Lili Bao,2,3 Zhengyan Wang,5 Zihan Li,2,3 Feng Ding,2,3 Huijuan Kuang,6,7 Huan Liu,8 Shenglong Tan,1 Xinyuan Qiu,1 Huan Jing,9 Shiyu Liu,2,3 Dandan Ma1 1Department of Endodontics, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, People’s Republic of China; 2State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Oral Biology, School of Stomatology, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 3State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 4Department of Gynecology and Obstetrics, Xijing Hospital, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 5Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan, 250012, People’s Republic of China; 6Department of Orthopaedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710061, People’s Republic of China; 7State Key Laboratory for Manufacturing System Engineering, Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of China; 8Department of Otolaryngology Head and Neck Surgery, Peking University Third Hospital, Beijing, 100871, People’s Republic of China; 9Department of Endodontics, Guangdong Provincial High-level Clinical Key Specialty, Guangdong Province Engineering Research Center of Oral Disease Diagnosis and Treatment, Peking University Shenzhen Hospital, Shenzhen, 518036, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dandan Ma, Stomatological Hospital, Southern Medical University, S366 Jiangnan Boulevard, Guangzhou, Guangdong, 510280, People’s Republic of China, Tel +86-20-34152996, Email mdd@smu.edu.cn Shiyu Liu, School of Stomatology, The Fourth Military Medical University, No. 145, West Changle Road, Xi’an, Shaanxi, 710032, People’s Republic of China, Tel +86-29-84772645, Email liushiyu@vip.163.comBackground: Osteoporosis is a major public health concern characterized by decreased bone density. …”
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16103
Fálétí’s Philosophical Sensibility
Published 2021-12-01“… Let us begin with an unfortunate fact: Adébáyọ̀ Fálétí is one major writer that is hardly anthologized. The problem could not have been that he wrote in Yorùbá because Fágúnwà is far more anthologized than he is. …”
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16104
Rome à la campagne : les décors en pierre de la villa de la Grande Boussue à Nouvelles (Mons, Belgique)
Published 2023-12-01“…Sawn slabs in Gris des Ardennes and Rance red marble form the major tones of the decoration. They are combined with complex geometric patterns, such as circular shapes in Trier diabase and Rance red marble, and rhombuses in Fior di Pesco and white marble. …”
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16105
The high-resolution global shipping emission inventory by the Shipping Emission Inventory Model (SEIM)
Published 2025-01-01“…In 2021, the ship activity dataset established based on AIS data covered 109 300 vessels globally (101 400 vessels reported by the United Nations Conference on Trade and Development). Concerning the major air pollutants and greenhouse gases, global ships emitted <span class="inline-formula">847.2×10<sup>6</sup></span> t of CO<span class="inline-formula"><sub>2</sub></span>, <span class="inline-formula">2.3×10<sup>6</sup></span> t of SO<span class="inline-formula"><sub>2</sub></span>, <span class="inline-formula">16.1×10<sup>6</sup></span> t of NO<span class="inline-formula"><sub><i>x</i></sub></span>, 791.2 kt of CO, 737.3 kt of HC (hydrocarbon), 415.5 kt of primary PM<span class="inline-formula"><sub>2.5</sub></span>, 61.6 kt of BC (black carbon), 210.3 kt of CH<span class="inline-formula"><sub>4</sub></span>, and 45.1 kt of N<span class="inline-formula"><sub>2</sub></span>O in 2021, accounting for 3.2 % of SO<span class="inline-formula"><sub>2</sub></span>, 14.2 % of NO<span class="inline-formula"><sub><i>x</i></sub></span>, and 2.3 % of CO<span class="inline-formula"><sub>2</sub></span> emissions from all global anthropogenic sources, based on the Community Emissions Data System (CEDS). …”
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16106
Comprehensive epidemiological evaluation of ruminant brucellosis and associated risk factors in some Egyptian Governorates
Published 2025-12-01“…The difficulty in accurately diagnosing all infected animals, particularly carriers, is a major limitation of eradication and control programs. …”
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16107
Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inf...
Published 2025-01-01“…IntroductionCritically ill patients suffer from a wide variety of clinical events, most of them leading to pro-inflammatory states such as sepsis or simply as consequence of major surgery. Many of these patients develop forms of acute kidney injury, heart or acute liver failure during intensive care. …”
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16108
Development, validation, and clinical application of a machine learning model for risk stratification and management of cervical cancer screening based on full-genotyping hrHPV tes...
Published 2025-02-01“…Funding: National Natural Science Foundation of China; Major Scientific Research Program for Young and Middle-aged Health Professionals of Fujian Province, China; Fujian Province Central Government-Guided Local Science and Technology Development Project; Fujian Province's Third Batch of Flexible Introduction of High-Level Medical Talent Teams; Fujian Provincial Natural Science Foundation of China; Fujian Provincial Science and Technology Innovation Joint Fund.…”
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16109
Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis
Published 2025-01-01“…Regarding melatonin in the CSF, indolamine levels did not correlate with its major oxidative-derived metabolite, i.e., AFMK. However, melatonin CSF levels were significantly reduced in AD patients but not in OT. …”
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16110
Révision de l’espèce Homo erectus (Dubois, 1893)
Published 2000-06-01“…When the phylogenetic pattern is reconsidered in a chronostratigraphic frame, it seems that a “boom” of speciation is happened in east Africa triggered by major climato-tectonic shift around 2,8 Ma. to 2,4 Ma. …”
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16111
Activités artisanales sur la rive droite de la Vesle à Reims/Durocortorum
Published 2022-11-01“…Henri-Henrot in Reims, was preceded by a major rescue archaeology excavation in 2008-2009, extending over a surface of 4,000 m2 and descending more than 3 m of stratigraphy. …”
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16112
A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy
Published 2025-01-01“…Background Non-proliferative and proliferative diabetic retinopathy are common complications of diabetes and a major cause of sight loss. Anti-vascular endothelial growth factor drugs represent a treatment option for people with diabetic retinopathy and are routinely used to treat various other eye conditions. …”
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16113
Farmers’ climate change perception, impacts and adaptation strategies in response to drought in the Northwest area of Bangladesh
Published 2025-04-01“…The study mainly examines major climate variables and their trends, farmers perception on climate change and drought, adaptation strategies and the factors affecting choice of those strategies. …”
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16114
Global, regional, and national trends in drug use disorder mortality rates across 73 countries from 1990 to 2021, with projections up to 2040: a global time-series analysis and mod...
Published 2025-01-01“…Summary: Background: Drug use disorder (DUD) poses a major public health crisis globally, necessitating immediate attention to global trends and future projections to develop effective health policies and interventions. …”
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16115
FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregn...
Published 2024-08-01“…For WP2, interviews will be conducted until data saturation and sample variance are achieved, that is, when no new major themes are being discovered. Based on previous similar pilot studies, this is anticipated to be approximately 15–25 interviews in both the parent and clinician groups. …”
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16116
Efficacy and safety of perioperative sintilimab plus platinum-based chemotherapy for potentially resectable stage IIIB non-small cell lung cancer (periSCOPE): an open-label, single...
Published 2025-01-01“…The primary endpoint was major pathological response (MPR). The key secondary endpoints included the objective response rate (ORR), radical resection (R0) rate, pathological complete response (pCR) rate, event-free survival (EFS), disease-free survival (DFS), OS, treatment-related adverse events (TRAEs), surgical complications, and surgery delay rate. …”
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16117
Towards a high-quality in situ observation network for oxygenated volatile organic compounds (OVOCs) in Europe: transferring metrological traceability to the field
Published 2025-01-01“…<p>Volatile organic compounds (VOCs) have a large impact on the oxidising capacity of the troposphere and are major precursors of tropospheric ozone and secondary atmospheric aerosols. …”
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16118
Comparative analysis of C-Reactive protein levels among Non-comorbid, Comorbid, and Multimorbid Hospitalized COVID-19 patients
Published 2025-01-01“…The objective of this study was to evaluate the association of major comorbidities such as ischemic heart diseases, diabetes, chronic kidney disease, hypertension, and lung infections e.g. tuberculosis with serum CRP levels in hospitalized COVID-19 patients. …”
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16119
Contribution à l’histoire de la boulangerie romaine : étude de « pains/galettes » découverts en Gaule
Published 2021-12-01“…These findings differ from the Metal Age specimens previously studied in Europe, which appear to contain a higher frequency of bran and glume remains. The major shift from hulled towards free-threshing cereals was motivated more by technical constraints weighing on the product intended for sale, than by new dietary habits: free-threshing wheat species could be directly processed. …”
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16120
Karel Janeček − a leading figure in Czech Music Theory and Pedagogy: his theoretical writings from the 1930s and 1940s
Published 2021-12-01“…His work as a teacher of players, singers, conductors, music directors and, most notably, composers served Janeček as an empirical testing ground for the premises, concepts, and systemic principles he came to formulate in his major books and essays. Viewed from a historical perspective, his most significant books include Základy moderní harmonie (Modern Harmony, 1949, published 1965), Hudební formy (Musical Forms, 1955), and Tektonika – nauka o stavbě skladeb (Tectonics: A Theory of the Structure of Compositions, 1968). …”
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