Efficacy and Safety of HAPC in Barrett's Esophagus – A Multicenter Italian Prospective Study by Davide Massimi, Roberta Maselli, Silvia Pecere, Cristiano Spada, Gianluca Andrisani, Francesco Maria Di Matteo, Antonella La Terra, Franco Coppola, Antonio Capogreco, Roberto De Sire, Ludovico Alfarone, Maddalena Menini, Marco Spadaccini, Cesare Hassan, Alessandro Repici

“…The secondary endpoints were safety in terms of major and minor adverse events (AEs) and tolerability, assessed using pain (0-10) and dysphagia (0-5) scores within 7 days post-ablation. …”
Get full text

Effect of smoking cessation on the likelihood of pancreatitis and pancreatic cancer by Xiao Han, Zouhua Xu, Dongmei Ma, Zhi Ling, Xiaowu Dong, Xuebing Yan, Yong Chen, Guotao Lu, Xudong Yin, Hongwei Xu

“…Introduction Tobacco smoking is a major risk factor for various diseases worldwide, including pancreatic exocrine diseases such as pancreatitis and pancreatic cancer (PC). …”
Get full text

Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis by Vinzenz Fleischer, Tobias Brummer, Muthuraman Muthuraman, Muthuraman Muthuraman, Falk Steffen, Milena Heldt, Maria Protopapa, Muriel Schraad, Gabriel Gonzalez-Escamilla, Sergiu Groppa, Stefan Bittner, Frauke Zipp

“…Finally, predictive causal modeling identified that LV mediates significant parts of the effect of GMV and sNfL on disability progression.ConclusionMultimodal biomarkers, i.e. different major surrogates for pathology derived from MRI, OCT and blood, inform about different parts of the disease pathology leading to clinical progression.…”
Get full text

Bridging incremental to transformative hazard management strategies on the Tule River Indian Reservation by Natalie Herbert, Caroline Beckman, Kerri Vera, Eric Coles, Thomas Kim, Seung-Hyun Cho, Gabrielle Wong-Parodi

“…Using a grounded theory approach to analyze practitioner interviews, our article makes two major contributions. First, we identify a conceptual framework by which practitioners connect people to each other and to place, from place to compounding hazards, and from vulnerabilities to hazard management strategies. …”
Get full text

Augmenting neurocognitive remediation therapy to Preventive Cognitive Therapy for partially remitted depressed patients: protocol of a pragmatic multicentre randomised controlled t... by Huibert Burger, Claudi Bockting, Marlies Brouwer, Gert J Geurtsen, Amanda M Legemaat, Johanne G J van der Stappen, Maria Semkovska, Isidoor O Bergfeld, Nicoline Lous, Damiaan A J P Denys

“…Introduction Major depressive disorder (MDD) affects 163 million people globally every year. …”
Get full text

Genotyping of extended-spectrum beta-lactamase-producing Escherichia coli isolated from wastewater of dairy farms in East Java, Indonesia by Fidi Nur Aini Eka Puji Dameanti, Sheila Marty Yanestria, Mustofa Helmi Effendi, Hani Plumeriastuti, Wiwiek Tyasningsih, Emmanuel Nnabuike Ugbo, Rahayu Sutrisno, Muhammad Ali Akramsyah Safri

“…Materials and Methods: Wastewater samples (n = 342) were collected from six major dairy regions in East Java: Pasuruan, Malang, Tulungagung, Blitar, Batu, and Kediri. …”
Get full text

Incidence of constrained condylar and hinged knee implants and mid- to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA) by Jake von Hintze, Ville Ponkilainen, Annette W-Dahl, Nils P Hailer, Ove Furnes, Anne M Fenstad, Mona Badawy, Alma B Pedersen, Martin Lindberg-Larsen, Mika J Niemeläinen, Keijo Mäkelä, Antti Eskelinen

“…Both designs showed consistent 15-year revision risks of 11–14%, with no major differences between them. The higher revision risk compared with MS TKAs may reflect the complexity of the surgeries. …”
Get full text

Robotic Versus Laparoscopic Liver Resection: A Nationwide Propensity Score Matched Analysis by Gabriela Pilz da Cunha, MD, Jasper P. Sijberden, MD, PhD, Susan van Dieren, PhD, Paul Gobardhan, MD, PhD, Daan J. Lips, MD, PhD, Türkan Terkivatan, MD, PhD, Hendrik A. Marsman, MD, PhD, Gijs A. Patijn, MD, PhD, Wouter K. G. Leclercq, MD, PhD, Koop Bosscha, MD, PhD, J. Sven D. Mieog, MD, PhD, Peter B. van den Boezem, MD, PhD, Maarten Vermaas, MD, PhD, Niels F. M. Kok, MD, PhD, Eric J. T. Belt, MD, PhD, Marieke T. de Boer, MD, PhD, Wouter J. M. Derksen, MD, PhD, Hans Torrenga, MD, PhD, Paul M. Verheijen, MD, PhD, Steven J. Oosterling, MD, PhD, Arjen M. Rijken, MD, PhD, Marielle M. E. Coolsen, MD, PhD, Mike S. L. Liem, MD, PhD, T.C. Khé Tran, MD, PhD, Michael F. Gerhards, MD, PhD, Vincent Nieuwenhuijs, MD, PhD, Mohammad Abu Hilal, MD, PhD, Marc G. Besselink, MD, PhD, Ronald M. van Dam, MD, PhD, Jeroen Hagendoorn, MD, PhD, Rutger-Jan Swijnenburg, MD, PhD, for the Dutch Hepatobiliary Audit Group

“…After PSM (781 RLR vs 781 LLR), RLR was associated with less blood loss (median: 100 mL [interquartile range (IQR): 50–300] vs 200 mL [IQR: 50–500], P = 0.002), less major blood loss (≥500 mL,18.6% vs 25.2%, P = 0.011), less conversions (4.9% vs 12.8%, P < 0.001), and shorter hospital stay (median: 3 days [IQR: 2–5] vs 4 days [IQR: 2–6], P < 0.001), compared with LLR. …”
Get full text

Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal) by Nuwadatta Subedi, Sunita Ranabhat, Sanjib Mani Regmi, Mukesh Mallik, Dela Singh, Shree Krishna Shrestha, Bandana Gurung, Arjun Bhattarai, Madan Prasad Baral, Sudhir Raman Parajuli, Ramchandra Bastola, Junu Shrestha, Sahisnuta Basnet, Eva Gauchan, Sabita Paudel

“…Although the perinatal and neonatal death rates have decreased recently, it still poses a major challenge to the health system of Nepal. The objective of the study is to determine the causes of perinatal deaths by integrating Minimally Invasive Tissue Sampling (MITS) in hospital perinatal deaths and incorporating verbal autopsy in community deaths in Kaski district of Nepal. …”
Get full text

A20 as a Potential Therapeutic Target for COVID‐19 by Yongyao Wu, Lilan He, Rong Li, Jiuxuan Li, Qing Zhao, Bin Shao

“…ABSTRACT Background Coronavirus disease 2019 (COVID‐19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is a major concern due to its astonishing prevalence and high fatality rate, especially among elderly people. …”
Get full text

Automatic Segmentation of Asphalt Cracks on Highways After Large-Scale and Severe Earthquakes Using Deep Learning-Based Approaches by Mehmet Yilmaz, Erkut Yalcin, Fatih Demir, Ahmet Munir Ozdemir, Muhammed Atar, Aysegul Gunes, Beyza Furtana Yalcin, Ertugrul Cambay

“…To achieve this, pixel-based labels were created by experts in the construction field by analyzing each pixel value. Following two major earthquakes, a unique dataset for segmenting roadway deterioration was created through intensive and detailed studies. …”
Get full text

Formation Characteristics of PCDD/Fs in the Co-combustion and Pyrolysis Process of Coal and Sewage Sludge by Mumin Rao, Xiangbo Zou, Ji Ye, Yunfeng Ma, Tieying Mao, Xiaoqing Lin, Xiaodong Li, Jianhua Yan, Shiwei Qin, Cao Kuang

“…The de novo synthesis should be the major formation pathway of PCDD/Fs in the co-combustion process of coal and SS. …”
Get full text

Multicriteria assessment of recently implemented conservation agriculture cropping systems across farmers’ plots in northwestern Cambodia by Sambo Pheap, Alexis Thoumazeau, Jun Murase, Vang Seng, Jean-Pierre Sarthou, Veng Sar, Linda Kimbo, Soklin Kheam, Pheakdey Chan, Pao Srean, Samrith Leang, Lyda Hok, Florent Tivet

“…Soil fertility depletion is a major challenge for annual rainfed cropping systems in the northwestern region of Cambodia which has recently undergone rapid agrarian changes. …”
Get full text

Optimization, characterization and biosafety of oregano, rosemary and mint oil mixture against Penicillium digitatum in citrus using L-optimal mixture design by Rahaf Khaled, Sara Mohamed, Amira Mohamed, Aya Khairy, Hesham Elhariry, Ashraf Bakry, Neima K. Elsenosy, Naglaa Ebeed, Salem S. Salem, Thanaa ElNoby, Samah H. Abu-Hussien

“…GC-MS analysis identified major compounds like cavarcol, caryophyllene, eucalyptol, phenols and levomenthol in oregano oil, contributing to its bioactivities. …”
Get full text

Effects of the physical form of starter feed on the intake, performance, and health of female Holstein calves by Í.R.R. Castro, G.B.C. Leite, I.F. Carrari, L.N.C. Silva, J.C.C. Chagas, D.D. More, M.I. Marcondes

“…Coincidently, PSF-fed animals sorted for small particles in the same sieve sizes. No major changes in blood profile were found (P > 0.05). …”
Get full text

Enhanced recovery pathway in adult patients with spinal deformity undergoing open thoracolumbar surgery by Qingyang Huang, Lang Xiao, Shuaikang Wang, Peng Cui, Di Han, Peng Wang, Shibao Lu

“…Abstract Purpose The poor prognosis of adult patients with spinal deformity following long-segment spinal fusion surgery remains a major concern. Our study aims to investigate the impact of an Enhanced Recovery After Surgery (ERAS) protocol on the prognosis of adult patients with spinal deformity. …”
Get full text

Design and Construction of an Aquaponics System: A Sustainable Approach to Enhancing Local Food Security in Offa, Nigeria by Rofiat Bunmi Mudashiru, Maryam Yusuf-Olawuyi, Aliyu Tijani, Lateef Umar, Francis Okeke, Oluwabunmi Adeyemi, Ismaila Amototo, Fatai Salaudeen

“… The design of an aquaponics system is a major drive in achieving a sustainable agricultural practice, tackling environmental problems, and food security. …”
Get full text

Dataset of microscale atmospheric flow and pollutant concentration large-eddy simulations for varying mesoscale meteorological forcing in an idealized urban environmentZenodo by Eliott Lumet, Thomas Jaravel, Mélanie C. Rochoux

“…First, the perturbed-parameter ensemble of LES enables to quantify and understand the effects of the mesoscale meteorological forcing and the internal variability of the atmospheric boundary layer, which has been identified as a major challenge in predicting atmospheric flow and pollutant dispersion in urban environments. …”
Get full text

Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…By more strict estimation at multifactorial analysis major risk factors were determined: age 30 to 59 years (p&lt;0,001), intake of alcoholic beverages in harmful dozes (over 16 points of AUDIT questionnaire, p=0,04), hypercholesterolemia (p=0,016). …”
Get full text

Clinical Characteristics of 31 Patients with Chest Pain Variant Asthma by Mao W, Gao Y, Sun W, Li J, Wang J, Wang Z, Zhang L, Huang K

“…Wenping Mao,1 Yanli Gao,2 Wanlu Sun,1 Jie Li,1 Jing Wang,1 Zhaomei Wang,1 Liming Zhang,1 Kewu Huang1 1Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Kewu Huang, Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China, Tel +86-010-85231167, Email kewuhuang@126.comPurpose: Asthma is a major public health challenge in China. Although chest pain variant asthma (CPVA) is not common in clinical practice, there are still a few people who only or mainly manifest as chest pain. …”
Get full text